☆ 4.7 Article

Design, Characterization, and Anticancer and Antimicrobial Activities of Mucoadhesive Oral Patches Loaded with Usnea barbata (L.) F. H. Wigg Ethanol Extract F-UBE-HPMC

ANTIOXIDANTS (2022)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Plant Sciences

Elemental Analysis and In Vitro Evaluation of Antibacterial and Antifungal Activities of Usnea barbata (L.) Weber ex F.H. Wigg from Calimani Mountains, Romania

Violeta Popovici et al.

Summary: This study analyzed the elemental composition of Usnea barbata lichen from the Calimani Mountains, Romania, and investigated its antibacterial and antifungal potential. The results showed that the lichen contained high levels of calcium and exhibited significant antimicrobial activity.

PLANTS-BASEL (2022)

添加到收藏夹

Review Biochemistry & Molecular Biology

Impact of Oral Microbiome in Periodontal Health and Periodontitis: A Critical Review on Prevention and Treatment

Mattia Di Stefano et al.

Summary: The oral cavity harbors a complex microbial community, which can lead to periodontal damage. Periodontal disease is a common chronic inflammatory condition globally, with diverse clinical manifestations.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

添加到收藏夹

Review Biochemistry & Molecular Biology

Anti-Microbial Peptides: Strategies of Design and Development and Their Promising Wound-Healing Activities

Fariba Fathi et al.

Summary: Antimicrobial peptides (AMPs) have become a focus as potential substitutes for commercial antibiotics, with some clinically approved AMPs showing effective wound-healing activity. Using bioinformatics servers and software, AMPs with wound-healing properties can be designed and developed.

MOLECULAR BIOLOGY REPORTS (2022)

添加到收藏夹

Article Spectroscopy

Usnic acid induced changes in biomolecules and their association with apoptosis in squamous carcinoma (A-431) cells: A flow cytometry, FTIR and DLS spectroscopic study

Madhuree Kumari et al.

Summary: This study demonstrates the cytotoxic potential of usnic acid against squamous carcinoma cells for the first time. Spectroscopic studies reveal changes in cell surface proteins, lipids, and DNA associated with this cytotoxicity. Usnic acid induces oxidative stress, alters protein and DNA structures, and leads to apoptosis in treated cells.

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY (2022)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Design and Characterization of Agarose/HPMC Buccal Films Bearing Ondansetron HCl In Vitro and In Vivo: Enhancement Using Iontophoretic and Chemical Approaches

Umair Jillani et al.

Summary: The study aimed to design and characterize mucoadhesive buccal films containing ondansetron hydrochloride (OND) using agarose (AG), hydroxypropyl methyl cellulose (HPMC), and glycerol. The buccal delivery of OND was enhanced by iontophoresis and chemical penetration enhancers. The effects of different formulation components on various parameters and drug release were investigated. The results showed a linear release profile and the relationship between polymer content and drug release. Physicochemical interactions were analyzed and no chemical interactions were found. Permeation studies revealed enhanced flux with iontophoresis and chemical enhancers. Pharmacokinetic and pharmacological studies in animals showed improved bioavailability and reduced emesis events. Histopathological examinations demonstrated no severe negative effects.

BIOMED RESEARCH INTERNATIONAL (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

Advances in the Characterization of Usnea barbata (L.) Weber ex FH Wigg from Calimani Mountains, Romania

Violeta Popovici et al.

Summary: This study conducted a comparative analysis between different parts of Usnea barbata lichens and found that the medulla-cortex fraction had the highest mineral content and total phenolic content, while the whole dried thallus had the highest antiradical activity. Furthermore, significant color differences and variations in metabolite content were observed among different parts of the lichen thallus.

APPLIED SCIENCES-BASEL (2022)

添加到收藏夹

Review Biochemistry & Molecular Biology

Apitherapy and Periodontal Disease: Insights into In Vitro, In Vivo, and Clinical Studies

Manoj Kumar et al.

Summary: Periodontal diseases, affecting a significant percentage of the global population, can be effectively treated using honeybee products due to their antimicrobial and anti-inflammatory properties. However, more randomized clinical trials are needed to assess their long-term effectiveness.

ANTIOXIDANTS (2022)

添加到收藏夹

Article Plant Sciences

Antioxidant, Cytotoxic, and Rheological Properties of Canola Oil Extract of Usnea barbata (L.) Weber ex F.H. Wigg from Calimani Mountains, Romania

Violeta Popovici et al.

Summary: This study investigated the antioxidant, cytotoxic, and rheological properties of Usnea barbata extract in canola oil. The results showed that the extract had high radical scavenging activity and cytotoxicity, making it suitable for potential pharmaceutical formulations. Additionally, the study suggested a possible synergism between lichen secondary metabolites, minerals, and canola oil phytoconstituents.

PLANTS-BASEL (2022)

添加到收藏夹

Article Infectious Diseases

Antimicrobial Activity of Biogenic Silver Nanoparticles from Syzygium aromaticum against the Five Most Common Microorganisms in the Oral Cavity

Erika Alejandra Jardon-Romero et al.

Summary: In this study, silver nanoparticles (AgNPs) were synthesized using clove extract through a green synthesis method, and their antimicrobial effect on oral microorganisms was evaluated. The results showed that AgNPs effectively inhibited the growth of various microorganisms commonly found in the oral cavity.

ANTIBIOTICS-BASEL (2022)

添加到收藏夹

Article Chemistry, Medicinal

Phenolic Secondary Metabolites and Antiradical and Antibacterial Activities of Different Extracts of Usnea barbata (L.) Weber ex F.H.Wigg from Calimani Mountains, Romania

Violeta Popovici et al.

Summary: Phenolic compounds in Usnea barbata extracts from Calimani Mountains, Romania were identified and quantified. The bioactivities, including antioxidant and antibacterial activities, of the extracts were investigated. The study revealed a positive correlation between the phenolic constituents and bioactivities of the extracts.

PHARMACEUTICALS (2022)

添加到收藏夹

Article Pharmacology & Pharmacy

Formulation and Development of Bioadhesive Oral Films Containing Usnea barbata (L.) FHWigg Dry Ethanol Extract (F-UBE-HPC) with Antimicrobial and Anticancer Properties for Potential Use in Oral Cancer Complementary Therapy

Violeta Popovici et al.

Summary: This study explores the potential use of Usnea barbata extract in oral cancer therapy. The formulated bioadhesive oral films containing the extract show favorable physical and chemical properties and exhibit anticancer activity. In vitro experiments demonstrate the extract's potential to induce apoptosis and inhibit DNA synthesis in oral cancer cells.

PHARMACEUTICS (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

Evaluation of Usnea barbata (L.) Weber ex FH Wigg Extract in Canola Oil Loaded in Bioadhesive Oral Films for Potential Applications in Oral Cavity Infections and Malignancy

Violeta Popovici et al.

Summary: Usnea lichens possess pharmacological effects that can be beneficial in oral medicine. This study explores the use of Usnea barbata extract in canola oil as an oral pharmaceutical formulation. Bioadhesive oral films loaded with the extract were formulated, characterized, and evaluated, demonstrating their potential pharmacological effects. The films showed antimicrobial properties against certain bacteria and fungi, and also exhibited cytotoxic effects on oral cancer cells. These findings suggest that Usnea barbata extract-loaded bioadhesive oral films could be a valuable phytotherapeutic formulation for oral infections and neoplasia.

ANTIOXIDANTS (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

The RP-HPLC method for analysis of usnic acid as potential marker of herbal drugs-based formulations containing Usnea barbata

V. A. N. J. A. TADIC et al.

Summary: This study developed a sensitive RP-HPLC method for the determination of usnic acid, a potential marker substance in a herbal product. The method involved extraction with methanol to separate usnic acid from other compounds. The established suitability, linearity, precision, accuracy, and selectivity/specificity of the method demonstrated its reliability in stability studies.

JOURNAL OF THE SERBIAN CHEMICAL SOCIETY (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

Lichens exerts an anti-proliferative effect on human breast and lung cancer cells through induction of apoptosis

Sule Ozturk et al.

Summary: This study investigated the anti-growth/apoptotic effects of methanol extracts of lichen species on human lung and breast cancer cell lines, with Usnea intermedia showing strong anti-growth activity in a dose-dependent manner. It was particularly cytotoxic against MDA-MB-231 and H1299 cells, with potential as a new alternative in cancer treatment.

DRUG AND CHEMICAL TOXICOLOGY (2021)

添加到收藏夹

Article Chemistry, Applied

Synthesis and cytotoxic evaluation of usnic acid benzylidene derivatives as potential anticancer agents

Van-Kieu Nguyen et al.

Summary: A series of usnic acid benzylidene derivatives were synthesized and evaluated for their anticancer activity, with compound 2e showing potent cytotoxicity against K562 leukemia cells without affecting HEK293 normal cells.

NATURAL PRODUCT RESEARCH (2021)

添加到收藏夹

Review Plant Sciences

Usnic acid: from an ancient lichen derivative to promising biological and nanotechnology applications

D. C. S. Macedo et al.

Summary: Usnic acid, a compound of natural origin, has various pharmacological activities, but it is also toxic. Research is utilizing nanotechnology to overcome obstacles in its pharmacological application and enhance therapeutic efficacy.

PHYTOCHEMISTRY REVIEWS (2021)

添加到收藏夹

Review Nutrition & Dietetics

Polyphenols and Human Health: The Role of Bioavailability

Chiara Di Lorenzo et al.

Summary: Polyphenols are a group of phytochemicals with potential health-promoting effects, classified as flavonoid and non-flavonoid molecules. Their positive effects on health are influenced by factors affecting their bioavailability, and recent studies have shown that their metabolites may have beneficial properties.

NUTRIENTS (2021)

添加到收藏夹

Article Pharmacology & Pharmacy

PHYTOCHEMICAL EVALUATION AND CYTOTOXICITY ASSAY OF LYTHRI HERBA EXTRACTS

Irina Mihaela Iancu et al.

Summary: Lythrum salicaria L., known for its traditional medicinal uses in Europe, exhibits strong antioxidant activity. Although the extract is non-toxic, it can cause cytological effects such as increased intercellular space and cell detachments.

FARMACIA (2021)

添加到收藏夹

Review Cell Biology

Ellagic Acid and Schisandrins: Natural Biaryl Polyphenols with Therapeutic Potential to Overcome Multidrug Resistance in Cancer

Sabesan Yoganathan et al.

Summary: Multidrug resistance, primarily mediated by P-glycoprotein (P-gp), poses a major challenge in cancer treatment. Developing small molecules to modulate P-gp activity can enhance cancer cell sensitivity to anticancer drugs. Natural polyphenols, including ellagic acid and derivatives, have emerged as promising compounds to overcome this mode of drug resistance.

CELLS (2021)

添加到收藏夹

Article Pharmacology & Pharmacy

Development and Characterization of Xanthan Gum and Alginate Based Bioadhesive Film for Pycnogenol Topical Use in Wound Treatment

Cinzia Pagano et al.

Summary: Pycnogenol (PYC) is a concentrate of phenolic compounds derived from French maritime pine, known for its antioxidant, anti-inflammatory, and antibacterial properties, making it suitable for treating open wounds. A bioadhesive film loaded with PYC was prepared, capable of absorbing wound fluid, releasing PYC gradually, and promoting keratinocyte growth, showing potential for topical formulations.

PHARMACEUTICS (2021)

添加到收藏夹

Article Pharmacology & Pharmacy

Formulation and Development of Oral Fast-Dissolving Films Loaded with Nanosuspension to Augment Paroxetine Bioavailability: In Vitro Characterization, Ex Vivo Permeation, and Pharmacokinetic Evaluation in Healthy Human Volunteers

Ahmed Hassen Elshafeey et al.

Summary: The study aimed to develop and optimize palatable oral fast-dissolving films (OFDFs) loaded with a paroxetine nanosuspension to increase the bioavailability of paroxetine. OFDFs offer convenience for patients with mental illness and are suitable for pediatric, elderly, and developmentally disabled patients.

PHARMACEUTICS (2021)

添加到收藏夹

Article Infectious Diseases

Analysis of Plant Origin Antibiotics against Oral Bacterial Infections Using In Vitro and In Silico Techniques and Characterization of Active Constituents

Abdul Rafey et al.

Summary: This study investigated 26 Ayurvedic medicinal plants traditionally used for treatment of oral bacterial infections and identified several plants with significant activities. The findings suggest that eugenol and 2-phenylethylisothiocyanate are major contributors towards inhibition of bacterial biofilms and quorum sensing.

ANTIBIOTICS-BASEL (2021)

添加到收藏夹

Article Medicine, General & Internal

Biomarkers involved in evaluation of platelets function in South-Eastern Romanian patients with hematological malignancies subtypes

Elena Matei et al.

Summary: This study investigates the relationship between the adaptive immune system (T cells) and the coagulation system in patients with AML and BCL, revealing that platelet activation status is associated with different stages of the diseases. The expressions of CD61 and CD42b on platelet membranes play important roles in this process.

MEDICINE (2021)

添加到收藏夹

Article Multidisciplinary Sciences

Hydroxypropylmethyl cellulose (HPMC) crosslinked keratin/hydroxyapatite (HA) scaffold fabrication, characterization and in vitro biocompatibility assessment as a bone graft for alveolar bone regeneration

Sandleen Feroz et al.

Summary: A novel hydroxypropyl methylcellulose (HPMC) crosslinked keratin scaffold containing hydroxyapatite for alveolar bone regeneration was developed using freeze drying technique. The scaffold showed highly porous structure, good in vitro biocompatibility, and potential for successful regeneration of alveolar bone.

HELIYON (2021)

添加到收藏夹

Article Plant Sciences

Antioxidant and Cytotoxic Activities of Usnea barbata (L.) F.H. Wigg. Dry Extracts in Different Solvents

Violeta Popovici et al.

Summary: Lichens, specifically Usnea barbata, are significant sources of antioxidants with high levels of usnic acid, polyphenols, and tannins contributing to their antioxidant properties. Different solvent extracts of Usnea barbata displayed varying levels of usnic acid, polyphenols, tannins, antioxidant activity, and cytotoxicity, with ethyl acetate and methanol extracts showing promising antioxidant effects but also high levels of cytotoxicity. Additionally, a moderate correlation was observed between the content of usnic acid, polyphenols, tannins, antioxidant activity, and cytotoxicity.

PLANTS-BASEL (2021)

添加到收藏夹

Review Microbiology

Lichens-A Potential Source for Nanoparticles Fabrication: A Review on Nanoparticles Biosynthesis and Their Prospective Applications

Reham Samir Hamida et al.

Summary: Green synthesis of nanoparticles using lichen extracts is a promising and cost-effective method to fabricate various types of nanomaterials with potential applications. Lichens have the ability to reduce bulk materials into nanoscale products and have shown promising catalytic and bioactive properties.

JOURNAL OF FUNGI (2021)

添加到收藏夹

Editorial Material Dentistry, Oral Surgery & Medicine

The 2021 WHO Resolution on Oral Health

Ira B. Lamster

INTERNATIONAL DENTAL JOURNAL (2021)

添加到收藏夹

Article Food Science & Technology

Use of natural plant extracts as a novel microbiological quality indicator in raw milk: An alternative for resazurin dye reduction method

Ranga Madushan et al.

Summary: This study introduced a new field-scale analytical tool for rapid screening of microbiological quality in raw milk using aqueous extracts of plant materials, specifically focusing on Hibiscus rosa-sinensis flower extract. The method showed high linearity, accuracy, and repeatability, making it a potential alternative for microbiological quality control in raw milk procurement.

LWT-FOOD SCIENCE AND TECHNOLOGY (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

Anticancer Activity of 2-O-caffeoyl Alphitolic Acid Extracted from the Lichen, Usnea barbata 2017-KL-10

Hae-Jung Chae et al.

Summary: Colorectal cancer is a life-threatening disease with poor prognosis for metastatic patients. Lichens have been identified as sources of bioactive metabolites, including anticancer properties. The study evaluated the anticancer effect of a lichen-derived metabolite, 2OCAA, on colorectal cancer cells, demonstrating its potential as a therapeutic candidate.

MOLECULES (2021)

添加到收藏夹

Article Pharmacology & Pharmacy

Formulation of Chewable Tablets Containing Carbamazepine-β-cyclodextrin Inclusion Complex and F-Melt Disintegration Excipient. The Mathematical Modeling of the Release Kinetics of Carbamazepine

Adina Magdalena Musuc et al.

Summary: This paper presents the synthesis and characterization of a carbamazepine-beta-cyclodextrin inclusion complex, as well as its application in chewable tablets and release kinetics modeling. The study indicates that the addition of super-disintegrant F-Melt can enhance the release rate of carbamazepine and reduce absorption variability by controlling the release mechanism.

PHARMACEUTICS (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

In Vitro Anticancer Activity and Oxidative Stress Biomarkers Status Determined by Usnea barbata (L.) FH Wigg. Dry Extracts

Violeta Popovici et al.

Summary: Lichens are a valuable resource for traditional medicine due to their diverse metabolites, with the study finding that acetone and ethyl acetate extracts of U. barbata showed the most potent anticancer effects against CAL-27 oral squamous carcinoma cells and V79 lung fibroblasts. The research suggests that the anticancer activity of U. barbata extracts may be partially due to an imbalance in antioxidant defense mechanisms leading to oxidative stress.

ANTIOXIDANTS (2021)

添加到收藏夹

Review Biochemistry & Molecular Biology

Beneficial Role of Antioxidant Secondary Metabolites from Medicinal Plants in Maintaining Oral Health

Manoj Kumar et al.

Summary: This review article discusses the safety and effectiveness of antioxidant essential oils extracted from medicinal plants in oral health, and summarizes the applications of essential oils from twenty commonly used medicinal plants in maintaining oral health. The article highlights the connection between oral diseases and oral microbiota, and discusses the role of antioxidant secondary metabolites in oral health.

ANTIOXIDANTS (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

Usnic Acid and Usnea barbata (L.) FH Wigg. Dry Extracts Promote Apoptosis and DNA Damage in Human Blood Cells through Enhancing ROS Levels

Violeta Popovici et al.

Summary: This study evaluated the cytotoxic potential of Usnea barbata and usnic acid on normal blood cells, finding that at high concentrations, both compounds induced apoptosis and DNA damage in human blood cells, along with increased ROS levels.

ANTIOXIDANTS (2021)

添加到收藏夹

Review Biochemistry & Molecular Biology

Plant-Based Antioxidant Extracts and Compounds in the Management of Oral Cancer

Suraj Prakash et al.

Summary: Oral cancer is a major cause of death globally, with a high prevalence in developing countries where chewing tobacco and betel nut is common. Conventional treatments like radiation, chemotherapy, and surgery for oral cancer often result in unwanted side effects, highlighting the need for safer treatment options. Bioactive compounds from medicinal plants have shown potential as therapeutic options for oral cancer by modulating cellular signaling pathways and protecting normal cells while inducing apoptosis in cancer cells.

ANTIOXIDANTS (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

Usnic acid induces apoptosis in human gastric cancer cells through ROS generation and DNA damage and causes up-regulation of DNA-PKcs and γ-H2A.X phosphorylation

Kunal Kumar et al.

CHEMICO-BIOLOGICAL INTERACTIONS (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

(+)-Usnic Acid Induces ROS-dependent Apoptosis via Inhibition of Mitochondria Respiratory Chain Complexes and Nrf2 Expression in Lung Squamous Cell Carcinoma

Wanchen Qi et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

添加到收藏夹

Review Pharmacology & Pharmacy

Nano- and Microcarriers as Drug Delivery Systems for Usnic Acid: Review of Literature

Ana Zugic et al.

PHARMACEUTICS (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Methanol Extract ofUsnea barbataInduces Cell Killing, Apoptosis, and DNA Damage against Oral Cancer Cells through Oxidative Stress

Jen-Yang Tang et al.

ANTIOXIDANTS (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Biomechanochemical Solid-State Synthesis of Silver Nanoparticles with Antibacterial Activity Using Lichens

Matej Balaz et al.

ACS SUSTAINABLE CHEMISTRY & ENGINEERING (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Characterization of Sunflower Oil Extracts from the Lichen Usnea barbata

Shereen Basiouni et al.

METABOLITES (2020)

添加到收藏夹

Article Pharmacology & Pharmacy

Current herbal medicine as an alternative treatment in dentistry: In vitro, in vivo and clinical studies

Ehsan Tafazoli Moghadam et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Investigation of chemical constituents and cytotoxic activity of the lichen Usnea undulata

Nguyen Thi Thu Tram et al.

VIETNAM JOURNAL OF CHEMISTRY (2020)

添加到收藏夹

Review Environmental Sciences

Review: Usnic acid-induced hepatotoxicity and cell death

Sukfan P. Kwong et al.

ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY (2020)

添加到收藏夹

Article Pharmacology & Pharmacy

Heparin appended ADH-anionic polysaccharide nanoparticles for site-specific delivery of usnic acid

Ashish Garg et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2019)

添加到收藏夹

Article Biochemistry & Molecular Biology

Mechanism of action of an old antibiotic revisited: Role of calcium ions in protonophoric activity of usnic acid

Yuri N. Antonenko et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2019)

添加到收藏夹

Article Biochemistry & Molecular Biology

Discovery of novel (+)-Usnic acid derivatives as potential anti-leukemia agents with pan-Pim kinases inhibitory activity

Shuxiang Wang et al.

BIOORGANIC CHEMISTRY (2019)

添加到收藏夹

Article Microbiology

Antibacterial Properties of Polyphenols: Characterization and QSAR (Quantitative Structure Activity Relationship) Models

Lynda Bouarab-Chibane et al.

FRONTIERS IN MICROBIOLOGY (2019)

添加到收藏夹

Review Substance Abuse

Effect of tobacco on periodontal disease and oral cancer

Yixin Zhang et al.

TOBACCO INDUCED DISEASES (2019)

添加到收藏夹

Article Ecology

In vitro antibacterial, antioxidant and cytotoxic activity of methanol-acetone extracts from Antarctic lichens (Usnea antarctica and Usnea aurantiaco-atra)

Pablo Londone-Bailon et al.

POLAR SCIENCE (2019)

添加到收藏夹

Article Surgery

Effect of ethyl acetate extract of usnea longissima on esophagogastric adenocarcinoma in rats

Renad Mammadov et al.

ACTA CIRURGICA BRASILEIRA (2019)

添加到收藏夹

Article Multidisciplinary Sciences

Inhibition of growth of U87MG human glioblastoma cells by Usnea longissima Ach.

Bugrahan Emsen et al.

ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS (2019)

添加到收藏夹

Article Microbiology

Yeast Species in the Oral Cavities of Older People: A Comparison between People Living in Their Own Homes and Those in Rest Homes

Nurulhuda Mohd Thiyahuddin et al.

JOURNAL OF FUNGI (2019)

添加到收藏夹

Article Physics, Applied

SPION@APTES@FA-PEG@Usnic Acid Bionanodrug for Cancer Therapy

L. Alpsoy et al.

JOURNAL OF SUPERCONDUCTIVITY AND NOVEL MAGNETISM (2018)

添加到收藏夹

Article Biochemistry & Molecular Biology

Secondary Metabolite Profiling of Species of the Genus Usnea by UHPLC-ESI-OT-MS-MS

Francisco Salgado et al.

MOLECULES (2018)

添加到收藏夹

Article Pharmacology & Pharmacy

Formulation and Characterization of Fast-Dissolving Sublingual Film of Iloperidone Using Box-Behnken Design for Enhancement of Oral Bioavailability

Vaishali Londhe et al.

AAPS PHARMSCITECH (2018)

添加到收藏夹

Article Education, Scientific Disciplines

The Use of Baker's Yeast in the Resazurin Reduction Test: A Simple, Low-Cost Method for Determining Cell Viability in Proliferation and Cytotoxicity Assays

Jayzon G. Bitacura

JOURNAL OF MICROBIOLOGY & BIOLOGY EDUCATION (2018)

添加到收藏夹

Article Pharmacology & Pharmacy

Usnea filipendula Induces Apoptosis in Human Colon Cancer Cell Lines

C. Disoma et al.

INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES (2018)

添加到收藏夹

Review Chemistry, Analytical

The Use of Hoechst Dyes for DNA Staining and Beyond

Jonas Bucevicius et al.

CHEMOSENSORS (2018)

添加到收藏夹

Article Chemistry, Medicinal

Carbazole alkaloids from Murraya koenigii trigger apoptosis and autophagic flux inhibition in human oral squamous cell carcinoma cells

Tanyarath Utaipan et al.

JOURNAL OF NATURAL MEDICINES (2017)

添加到收藏夹

Review Chemistry, Medicinal

Atranorin - An Interesting Lichen Secondary Metabolite

Elzbieta Studzinska-Sroka et al.

MINI-REVIEWS IN MEDICINAL CHEMISTRY (2017)

添加到收藏夹

Review Plant Sciences

Antioxidant potential of lichen species and their secondary metabolites. A systematic review

Carlos Fernandez-Moriano et al.

PHARMACEUTICAL BIOLOGY (2016)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Resazurin-based 96-well plate microdilution method for the determination of minimum inhibitory concentration of biosurfactants

Mohamed Elshikh et al.

BIOTECHNOLOGY LETTERS (2016)

添加到收藏夹

Article Pharmacology & Pharmacy

In vitro/in vivo evaluation of an optimized fast dissolving oral film containing olanzapine co-amorphous dispersion with selected carboxylic acids

Eman Magdy Maher et al.

DRUG DELIVERY (2016)

添加到收藏夹

Editorial Material Dentistry, Oral Surgery & Medicine

A new definition for oral health developed by the FDI World Dental Federation opens the door to a universal definition of oral health

Michael Glick et al.

INTERNATIONAL DENTAL JOURNAL (2016)

添加到收藏夹

Article Multidisciplinary Sciences

Evaluation of Anticancer and Antioxidant Activity of a Commercially Available CO2 Supercritical Extract of Old Man's Beard (Usnea barbata)

Ana Zugic et al.

PLOS ONE (2016)

添加到收藏夹

Review Pharmacology & Pharmacy

Thin films as an emerging platform for drug delivery

Sandeep Karki et al.

ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES (2016)

添加到收藏夹

Article Oncology

Marine alkaloid Monanchocidin a overcomes drug resistance by induction of autophagy and lysosomal membrane permeabilization

Sergey A. Dyshlovoy et al.

ONCOTARGET (2015)

添加到收藏夹

Article Pharmacology & Pharmacy

Design, development and characterization of buccal bioadhesive films of Doxepin for treatment of odontalgia

H. Castan et al.

DRUG DELIVERY (2015)

添加到收藏夹

Article Chemistry, Medicinal

Formulation and optimization of a novel oral fast dissolving film containing drug nanoparticles by Box-Behnken design-response surface methodology

Chengying Shen et al.

DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY (2014)

添加到收藏夹

Article Biochemistry & Molecular Biology

Bioadhesive okra polymer based buccal patches as platform for controlled drug delivery

Gurpreet Kaur et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2014)

添加到收藏夹

Review Dentistry, Oral Surgery & Medicine

Human Papillomavirus (HPV)-associated Oral Cancers and Treatment Strategies

N. Sathish et al.

JOURNAL OF DENTAL RESEARCH (2014)

添加到收藏夹

Review Biochemistry & Molecular Biology

Antioxidant Activity and Mechanisms of Action of Natural Compounds Isolated from Lichens: A Systematic Review

Pollyanna A. S. White et al.

MOLECULES (2014)

添加到收藏夹

Article Dentistry, Oral Surgery & Medicine

Oral squamous cell carcinoma: clinicopathological features from 346 cases from a single Oral Pathology service during an 8-year period

Fabio Ramoa Pires et al.

JOURNAL OF APPLIED ORAL SCIENCE (2013)

添加到收藏夹

Review Plant Sciences

Lichens: a promising source of antibiotic and anticancer drugs

Gajendra Shrestha et al.

PHYTOCHEMISTRY REVIEWS (2013)

添加到收藏夹

Article Chemistry, Medicinal

Cytotoxic Activity and Antioxidant Capacity of Purified Lichen Metabolites: An In Vitro Study

Fabrizia Brisdelli et al.

PHYTOTHERAPY RESEARCH (2013)

添加到收藏夹

Article Plant Sciences

Brine shrimp lethality assay 'an effective prescreen': Microwave-assisted synthesis, BSL toxicity and 3DQSAR studies-based designing, docking and antitumor evaluation of potent chalcones

Samina Nazir et al.

PHARMACEUTICAL BIOLOGY (2013)

添加到收藏夹

Article Multidisciplinary Sciences

Visualization of caspase-3-like activity in cells using a genetically encoded fluorescent biosensor activated by protein cleavage

Jiao Zhang et al.

NATURE COMMUNICATIONS (2013)

添加到收藏夹

Article Toxicology

Redox characterization of usnic acid and its cytotoxic effect on human neuron-like cells (SH-SY5Y)

Thallita Kelly Rabelo et al.

TOXICOLOGY IN VITRO (2012)

添加到收藏夹

Article Nutrition & Dietetics

Anticancer property of gallic acid in A549, a human lung adenocarcinoma cell line, and possible mechanisms

Dharmendra K. Maurya et al.

JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION (2011)

添加到收藏夹

Article Chemistry, Applied

Effects of various plasticizers on mechanical and water vapor barrier properties of gelatin films

Na Cao et al.

FOOD HYDROCOLLOIDS (2009)

添加到收藏夹

Article Polymer Science

Understanding of the Plasticizing Effects of Glycerol and PEG 400 on Chitosan Films Using Solid-State NMR Spectroscopy

Attila Domjan et al.

MACROMOLECULES (2009)

添加到收藏夹

Article Plant Sciences

A Rapid Method to Quantify Fungicide Sensitivity in the Brown Rot Pathogen Mondinia fructicola

Kerik D. Cox et al.

PLANT DISEASE (2009)

添加到收藏夹

Article Pharmacology & Pharmacy

Preparation and evaluation of buccal bioadhesive films containing clotrimazole

S. Singh et al.

AAPS PHARMSCITECH (2008)

添加到收藏夹

Article Pharmacology & Pharmacy

Formulation and Characterization of Mucoadhesive Buccal Films of Glipizide

Mona Semalty et al.

INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES (2008)

添加到收藏夹

Article Materials Science, Multidisciplinary

Preparation of thermo-responsive acrylic hydrogels useful for the application in transdermal drug delivery systems

Trong-Ming Don et al.

MATERIALS CHEMISTRY AND PHYSICS (2008)

添加到收藏夹

Article Pharmacology & Pharmacy

Nanoencapsulation of usnic acid: An attempt to improve antitumour activity and reduce hepatotoxicity

Noemia Pereira da Silva Santos et al.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2006)

添加到收藏夹

Article Multidisciplinary Sciences

Caspases 3 and 7: Key mediators of mitochondrial events of apoptosis

SA Lakhani et al.

SCIENCE (2006)

添加到收藏夹

Article Chemistry, Applied

Water sorption and mechanical properties of cassava starch films and their relation to plasticizing effect

S Mali et al.

CARBOHYDRATE POLYMERS (2005)

添加到收藏夹

Article Chemistry, Multidisciplinary

Development of mucoadhesive patches for buccal administration of ibuprofen

L Perioli et al.

JOURNAL OF CONTROLLED RELEASE (2004)

添加到收藏夹

Article Pharmacology & Pharmacy

Mucoadhesive buccal patches of miconazole nitrate: in vitro/in vivo performance and effect of ageing

NA Nafee et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2003)

添加到收藏夹

Article Medicine, General & Internal

Severe hepatotoxicity associated with the dietary supplement LipoKinetix

JT Favreau et al.

ANNALS OF INTERNAL MEDICINE (2002)

添加到收藏夹

Article Biochemistry & Molecular Biology

Hydrogen peroxide dose dependent induction of cell death or hypertrophy in cardiomyocytes

QM Chen et al.

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2000)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.