4.7 Review

Targeting Oxidative Stress in Intracerebral Hemorrhage: Prospects of the Natural Products Approach

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Pharmacology & Pharmacy

The natural (poly)phenols as modulators of microglia polarization via TLR4/NF-κB pathway exert anti-inflammatory activity in ischemic stroke

Ruoqi Li et al.

Summary: This article discusses the role of inflammation in stroke and the therapeutic approach of modulating microglial phenotypes through the TLR4/NF-kappa B signaling pathway. It is found that dietary (poly)phenols have anti-inflammatory properties and provide protective effects on ischemic stroke.

EUROPEAN JOURNAL OF PHARMACOLOGY (2022)

Review Biochemistry & Molecular Biology

Reconceptualization of Hormetic Responses in the Frame of Redox Toxicology

Zoi Skaperda et al.

Summary: Exposure to low levels of toxic agents or stressful stimuli leads to cellular adaptive mechanisms, displaying hormesis and redox adaptations. The dose, duration of exposure, and the specific cell, tissue or organ exposed play crucial roles in the hormetic effect.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

Article Neurosciences

Cordycepin Ameliorates Intracerebral Hemorrhage Induced Neurological and Cognitive Impairments Through Reducing Anti-Oxidative Stress in a Mouse Model

Qingbao Yan et al.

Summary: Cordycepin treatment can ameliorate neurological deficits, brain edema, anxiety, cognitive impairments, oxidative stress, and antioxidant capacity in ICH mice.

JOURNAL OF STROKE & CEREBROVASCULAR DISEASES (2022)

Review Physiology

(-)-Epicatechin and cardiometabolic risk factors: a focus on potential mechanisms of action

Ezequiel J. Hid et al.

Summary: This review summarizes experimental evidence on the beneficial effects of (-)-epicatechin (EC) attenuating major cardiometabolic risk factors, including dyslipidemias, obesity, hyperglycemia, and hypertension. The assessment of EC metabolism highlights the importance of both host metabolism-derived conjugated-EC metabolites and microbiota-derived species. EC appears to have significant effects on regulating oxidant production, nitric oxide production, and energy homeostasis in processes associated with cardiometabolic diseases.

PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2022)

Article Medicine, Research & Experimental

Neuroprotective Effect of Chrysophanol as a PI3K/AKT/mTOR Signaling Inhibitor in an Experimental Model of Autologous Blood-induced Intracerebral Hemorrhage

Kuldeep Singh Jadaun et al.

Summary: The PI3K/AKT/mTOR pathway inhibitor chrysophanol (CPH) showed neuroprotective effects and improved neurological dysfunctions in rats with intracerebral hemorrhage (ICH). It decreased the expression levels of PI3K, AKT, and mTOR proteins, and modulated apoptotic markers, inflammatory cytokines, and oxidative stress markers in the brain.

CURRENT MEDICAL SCIENCE (2022)

Article Pharmacology & Pharmacy

Dauricine alleviated secondary brain injury after intracerebral hemorrhage by upregulating GPX4 expression and inhibiting ferroptosis of nerve cells

Chiwei Peng et al.

Summary: This study investigates the therapeutic effect of Dauricine on intracerebral hemorrhage by studying the impact of ferroptosis on brain injury. The results demonstrate that Dauricine inhibits ferroptosis and reduces brain damage by upregulating the co-expression of glutathione peroxidase 4 (GPX4) and glutathione reductase (GSR).

EUROPEAN JOURNAL OF PHARMACOLOGY (2022)

Article Neurosciences

Crocin Alleviates Intracerebral Hemorrhage-Induced Neuronal Ferroptosis by Facilitating Nrf2 Nuclear Translocation

Fei Wang et al.

Summary: This study investigated the protective role of crocin in brain injury caused by intracerebral hemorrhage (ICH) and identified its mechanism. The results showed that crocin can alleviate ICH-induced brain edema and neurological deficits and exert its effect by inhibiting ferroptosis.

NEUROTOXICITY RESEARCH (2022)

Article Pharmacology & Pharmacy

Traditional Chinese medicine use in the pathophysiological processes of intracerebral hemorrhage and comparison with conventional therapy

Tian Duan et al.

Summary: This paper summarizes the mechanisms by which traditional Chinese medicine improves cerebral injury after intracerebral hemorrhage (ICH) and compares them with conventional Western medicine. The findings provide clues and references for the clinical application of traditional Chinese medicine in the prevention and treatment of hemorrhagic stroke and the development of new drugs.

PHARMACOLOGICAL RESEARCH (2022)

Article Behavioral Sciences

Artemisinin upregulates neural cell adhesion molecule L1 to attenuate neurological deficits after intracerebral hemorrhage in mice

Jianjiang Wang et al.

Summary: This study investigates the effects of artemisinin (ART) on neurological recovery in a mouse model of intracerebral hemorrhage (ICH) induced by collagenase. The results show that ART can upregulate L1 expression to alleviate brain edema, reduce oxidative stress, and inhibit inflammation, thus improving the neurological outcome in mice with ICH.

BRAIN AND BEHAVIOR (2022)

Review Immunology

Oxidative Stress Following Intracerebral Hemorrhage: From Molecular Mechanisms to Therapeutic Targets

Yan Zhang et al.

Summary: This article discusses the sources and possible molecular mechanisms of oxidative stress in causing brain injury in intracerebral hemorrhage (ICH), as well as anti-oxidative stress strategies to alleviate the devastation of ICH.

FRONTIERS IN IMMUNOLOGY (2022)

Review Biochemistry & Molecular Biology

Review on the Pharmacological Properties of Phillyrin

Chenyu Zhou et al.

Summary: Phillyrin is an effective lignan glycoside extracted from Forsythia suspensa (Thunb.) Vahl, a traditional Chinese medicine. It has various pharmacological effects, such as anti-inflammatory, anti-obesity, and anti-tumor. Studies have shown that phillyrin is highly effective and has low toxicity. However, there are few conclusive reviews on its pharmacological activities, indicating the need for further research.

MOLECULES (2022)

Article Pharmacology & Pharmacy

The neuroprotective effect of phillyrin in intracerebral hemorrhagic mice is produced by activation of the Nrf2 signaling pathway

Xin Guo et al.

Summary: The study reveals the potential therapeutic role of phillyrin in alleviating apoptosis and oxidative stress induced by ICH through activation of the Nrf2 signaling pathway.

EUROPEAN JOURNAL OF PHARMACOLOGY (2021)

Article Nanoscience & Nanotechnology

Curcumin Nanoparticles Inhibiting Ferroptosis for the Enhanced Treatment of Intracerebral Hemorrhage

Cong Yang et al.

Summary: Intracerebral hemorrhage (ICH) is a severe form of stroke with pathology related to ferroptosis, a type of programmed cell death. Curcumin (Cur) has therapeutic potential for ICH but faces challenges due to poor solubility and bioavailability. Encapsulating Cur in nanoparticles (Cur-NPs) improves its delivery to the brain and shows promising therapeutic effects in treating ICH, including suppressing ferroptosis.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2021)

Review Biochemistry & Molecular Biology

A Systematic Review of the Biological Effects of Cordycepin

Masar Radhi et al.

Summary: Cordycepin demonstrates significant effects on cell survival, proliferation, inflammation, and signal transduction, with potential therapeutic benefits on various diseases, especially in reducing tumor growth and suppressing inflammation.

MOLECULES (2021)

Article Cell Biology

Luteolin Confers Cerebroprotection after Subarachnoid Hemorrhage by Suppression of NLPR3 Inflammasome Activation through Nrf2-Dependent Pathway

Zi-Huan Zhang et al.

Summary: Luteolin protects against subarachnoid hemorrhage by inhibiting the NLRP3 inflammasome signaling pathway, which may be modulated by Nrf2 activation.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2021)

Review Pharmacology & Pharmacy

The role of microbiota-gut-brain axis in neuropsychiatric and neurological disorders

Katarzyna Socala et al.

Summary: Emerging evidence suggests that gut microbiota play a crucial role in the bidirectional communication between the gut and brain, influencing neural development, neurotransmission, and behavior. Studies have explored the role of microbiota in various neuropsychiatric and neurological disorders, including depression, anxiety, schizophrenia, autism spectrum disorders, Parkinson's disease, migraine, and epilepsy. This review discusses data from both preclinical experiments and clinical reports, highlighting the effects of probiotic, prebiotic, or antibiotic treatments, as well as fecal microbiota transplantation.

PHARMACOLOGICAL RESEARCH (2021)

Review Cell Biology

Mechanisms of Oxidative Stress and Therapeutic Targets following Intracerebral Hemorrhage

Zhenjia Yao et al.

Summary: This review provides an overview of the pathogenic mechanisms of brain injury following intracerebral hemorrhage and discusses the impact of oxidative stress on brain injury, as well as therapeutic strategies to mitigate brain injury.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2021)

Review Neurosciences

Inflammation and Oxidative Stress: Potential Targets for Improving Prognosis After Subarachnoid Hemorrhage

Fan Wu et al.

Summary: Subarachnoid hemorrhage (SAH) has a high mortality rate and often leads to long-term disability and cognitive impairment in patients. Neuroinflammation and oxidative stress are believed to play a negative role in neurofunctional deficits after SAH, with various cellular and acellular components being involved in the regulation of these processes. This review aims to provide new insights for clinical treatment to improve the prognosis of SAH by exploring the role of different components in secondary inflammation and oxidative stress.

FRONTIERS IN CELLULAR NEUROSCIENCE (2021)

Article Nutrition & Dietetics

Beneficial Effects of Ursolic Acid and Its Derivatives-Focus on Potential Biochemical Mechanisms in Cardiovascular Conditions

Jakub Erdmann et al.

Summary: Ursolic acid (UA) is a natural compound found in various plants with anti-inflammatory and anti-apoptotic properties. Its most beneficial effects appear to be through inhibition of NF-kappa B-mediated inflammatory pathways and scavenging of reactive oxygen species, potentially making it a promising candidate for cardiovascular disease management.

NUTRIENTS (2021)

Article Biochemistry & Molecular Biology

Isorhynchophylline Relieves Ferroptosis-Induced Nerve Damage after Intracerebral Hemorrhage Via miR-122-5p/TP53/SLC7A11 Pathway

Haikang Zhao et al.

Summary: The study shows that IRN can protect neurons from ICH-induced ferroptosis via the miR-122-5p/TP53/SLC7A11 pathway, providing a potential therapeutic mechanism for ICH.

NEUROCHEMICAL RESEARCH (2021)

Article Pharmacology & Pharmacy

Baicalin Inhibits Ferroptosis in Intracerebral Hemorrhage

Lining Duan et al.

Summary: Intracerebral hemorrhage (ICH) is a subtype of stroke with high mortality and disability rates, where ferroptosis plays a dominant role in its pathogenesis. Baicalin, a main active ingredient of Chinese herbal medicine, exhibits neuroprotective effects against ICH-induced brain injury by inhibiting ferroptosis and shows potential as a therapeutic drug for ICH treatment.

FRONTIERS IN PHARMACOLOGY (2021)

Review Neurosciences

The role of complement in brain injury following intracerebral hemorrhage: A review

Katherine Holste et al.

Summary: Intracerebral hemorrhage (ICH) leads to activation of the complement cascade, resulting in brain edema/injury, but inhibition of specific components of the complement cascade can reduce edema and improve functional outcomes. Additionally, complement plays a significant role in neurologic recovery after ICH.

EXPERIMENTAL NEUROLOGY (2021)

Article Cell Biology

Puerarin attenuates intracerebral hemorrhage-induced early brain injury possibly by PI3K/Akt signal activation-mediated suppression of NF-κB pathway

Jun Zeng et al.

Summary: Puerarin (PUE) can significantly reduce neurological deficits and early brain injury (EBI) induced by intracerebral hemorrhage (ICH), possibly by activating the PI3K/Akt signal to inhibit the NF-kappa B pathway and regulate inflammation, oxidative stress, and apoptotic pathways.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2021)

Correction Biotechnology & Applied Microbiology

Targeting oxidative stress in disease: promise and limitations of antioxidant therapy (Jun, 10.1038/s41573-021-00233-1, 2021)

Henry Jay Forman et al.

NATURE REVIEWS DRUG DISCOVERY (2021)

Review Cell Biology

Role of Polyphenols as Antioxidant Supplementation in Ischemic Stroke

Yuan Zhou et al.

Summary: Stroke is the second most common cause of death globally and the leading cause of death in China. Oxidative stress plays a crucial role in the pathogenesis of cerebral ischemia injury, making antioxidants a potential therapeutic target for ischemic stroke. Some polyphenols have been found to have strong antioxidant effects on reactive oxygen species generation and oxidative stress after ischemic stroke.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2021)

Article Biochemistry & Molecular Biology

Peroxiredoxin 2 oxidation reveals hydrogen peroxide generation within erythrocytes during high-dose vitamin C administration

Andree G. Pearson et al.

Summary: Intravenous infusion of high dose vitamin C increases intracellular ascorbate levels in erythrocytes, leading to H2O2 generation and oxidation of Prx2. Further investigation is needed to understand the impact of increased erythrocyte Prx2 oxidation.

REDOX BIOLOGY (2021)

Review Biotechnology & Applied Microbiology

Curcumin, the golden spice in treating cardiovascular diseases

Hong Li et al.

BIOTECHNOLOGY ADVANCES (2020)

Article Chemistry, Medicinal

Parthenolide ameliorates intracerebral hemorrhage-induced brain injury in rats

Jun-an Wang et al.

PHYTOTHERAPY RESEARCH (2020)

Review Pharmacology & Pharmacy

Enhancing the potential preclinical and clinical benefits of quercetin through novel drug delivery systems

Rubiya Khursheed et al.

DRUG DISCOVERY TODAY (2020)

Review Biochemistry & Molecular Biology

Protective effects of polydatin on multiple organ ischemia-reperfusion injury

Zhicheng Sun et al.

BIOORGANIC CHEMISTRY (2020)

Article Neurosciences

Gastrodin Attenuates Neuronal Apoptosis and Neurological Deficits after Experimental Intracerebral Hemorrhage

Xi-chang Liu et al.

JOURNAL OF STROKE & CEREBROVASCULAR DISEASES (2020)

Review Endocrinology & Metabolism

Potential therapeutic targets for intracerebral hemorrhage-associated inflammation: An update

Honglei Ren et al.

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2020)

Article Biochemistry & Molecular Biology

Effect of Polydatin on Neurological Function and the Nrf2 Pathway during Intracerebral Hemorrhage

Xiumin Zhao et al.

JOURNAL OF MOLECULAR NEUROSCIENCE (2020)

Review Clinical Neurology

Intracerebral haemorrhage: from clinical settings to animal models

Qian Bai et al.

STROKE AND VASCULAR NEUROLOGY (2020)

Review Pharmacology & Pharmacy

The birth of artemisinin

Nan Ma et al.

PHARMACOLOGY & THERAPEUTICS (2020)

Article Multidisciplinary Sciences

IL-4/STAT6 signaling facilitates innate hematoma resolution and neurological recovery after hemorrhagic stroke in mice

Jing Xu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Article Food Science & Technology

Therapeutic potentials of crocin in medication of neurological disorders

Salman Ahmed et al.

FOOD AND CHEMICAL TOXICOLOGY (2020)

Review Pharmacology & Pharmacy

Naringenin and naringin in cardiovascular disease prevention: A preclinical review

Reza Heidary Moghaddam et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2020)

Review Biochemistry & Molecular Biology

Advances in chemistry and bioactivity of parthenolide

Robert R. A. Freund et al.

NATURAL PRODUCT REPORTS (2020)

Article Medicine, General & Internal

Neuroprotective effects of quercetin on cerebral vasospasm following experimental subarachnoid haemorrhage in rats

Sanser Gul et al.

TURKISH JOURNAL OF MEDICAL SCIENCES (2020)

Review Biochemistry & Molecular Biology

A Review of Curcumin and Its Derivatives as Anticancer Agents

Mhd Anas Tomeh et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Article Clinical Neurology

Allicin attenuates early brain injury after experimental subarachnoid hemorrhage in rats

Jiang Shao et al.

JOURNAL OF CLINICAL NEUROSCIENCE (2019)

Review Pharmacology & Pharmacy

Bakuchiol: A newly discovered warrior against organ damage

Zhenlong Xin et al.

PHARMACOLOGICAL RESEARCH (2019)

Article Clinical Neurology

Global brain inflammation in stroke

Kaibin Shi et al.

LANCET NEUROLOGY (2019)

Review Pharmacology & Pharmacy

Chrysophanol: a review of its pharmacology, toxicity and pharmacokinetics

Long Xie et al.

JOURNAL OF PHARMACY AND PHARMACOLOGY (2019)

Review Pharmacology & Pharmacy

Pathophysiological Mechanisms and Potential Therapeutic Targets in Intracerebral Hemorrhage

Zhiwei Shao et al.

FRONTIERS IN PHARMACOLOGY (2019)

Article Nanoscience & Nanotechnology

Nanoparticles Mediating the Sustained Puerarin Release Facilitate Improved Brain Delivery to Treat Parkinson's Disease

Tongkai Chen et al.

ACS APPLIED MATERIALS & INTERFACES (2019)

Review Food Science & Technology

Therapeutic potential of naringin in neurological disorders

Salman Ahmed et al.

FOOD AND CHEMICAL TOXICOLOGY (2019)

Review Chemistry, Medicinal

Oleuropein: A natural antioxidant molecule in the treatment of metabolic syndrome

Javed Ahamad et al.

PHYTOTHERAPY RESEARCH (2019)

Review Medicine, General & Internal

Reformulating Pro-Oxidant Microglia in Neurodegeneration

Juan Garcia-Revilla et al.

JOURNAL OF CLINICAL MEDICINE (2019)

Article Cardiac & Cardiovascular Systems

Limitations of Animal Studies for Predicting Toxicity in Clinical Trials Is it Time to Rethink Our Current Approach?

Gail A. Van Norman

JACC-BASIC TO TRANSLATIONAL SCIENCE (2019)

Review Biochemistry & Molecular Biology

The effects of polyphenols and other bioactives on human health

Cesar G. Fraga et al.

FOOD & FUNCTION (2019)

Article Biochemistry & Molecular Biology

The in silico and in vivo evaluation of puerarin against Alzheimer's disease

Song Liu et al.

FOOD & FUNCTION (2019)

Review Medicine, Research & Experimental

Antioxidant effects and mechanism of silymarin in oxidative stress induced cardiovascular diseases

Abdoh Taleb et al.

BIOMEDICINE & PHARMACOTHERAPY (2018)

Article Biochemistry & Molecular Biology

Dietary astaxanthin can accumulate in the brain of rats

Yuki Manabe et al.

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2018)

Article Integrative & Complementary Medicine

Herbal Medicine in Ischemic Stroke: Challenges and Prospective

Bhakta Prasad Gaire

CHINESE JOURNAL OF INTEGRATIVE MEDICINE (2018)

Review Integrative & Complementary Medicine

Herbal medicine for hemorrhage-related hydrocephalus: A systematic review of randomised controlled trials

Bongki Park et al.

COMPLEMENTARY THERAPIES IN MEDICINE (2018)

Review Pharmacology & Pharmacy

Research review on the pharmacological effects of astragaloside IV

Lei Li et al.

FUNDAMENTAL & CLINICAL PHARMACOLOGY (2017)

Article Medicine, Research & Experimental

Luteolin protects mice from severe acute pancreatitis by exerting HO-1-mediated anti-inflammatory and antioxidant effects

Jie Xiong et al.

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2017)

Review Biochemistry & Molecular Biology

Recent Advances in Momordica charantia: Functional Components and Biological Activities

Shuo Jia et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)

Article Multidisciplinary Sciences

Neutrophil polarization by IL-27 as a therapeutic target for intracerebral hemorrhage

Xiurong Zhao et al.

NATURE COMMUNICATIONS (2017)

Article Biochemistry & Molecular Biology

Fungal Cordycepin Biosynthesis Is Coupled with the Production of the Safeguard Molecule Pentostatin

Yongliang Xia et al.

CELL CHEMICAL BIOLOGY (2017)

Article Medicine, Research & Experimental

Silymarin prevents NLRP3 inflammasome activation and protects against intracerebral hemorrhage

Raorao Yuan et al.

BIOMEDICINE & PHARMACOTHERAPY (2017)

Review Pharmacology & Pharmacy

Targeting the Nrf2-Heme Oxygenase-1 Axis after Intracerebral Hemorrhage

Jing Chen-Roetling et al.

CURRENT PHARMACEUTICAL DESIGN (2017)

Review Cell Biology

Oxidative Stress in Intracerebral Hemorrhage: Sources, Mechanisms, and Therapeutic Targets

Xin Hu et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2016)

Article Multidisciplinary Sciences

Pharmacokinetic comparison between quercetin and quercetin 3-O-β-glucuronide in rats by UHPLC-MS/MS

Le-Le Yang et al.

SCIENTIFIC REPORTS (2016)

Review Biotechnology & Applied Microbiology

Biotechnological production and applications of Cordyceps militaris, a valued traditional Chinese medicine

Jian Dong Cui

CRITICAL REVIEWS IN BIOTECHNOLOGY (2015)

Article Biochemistry & Molecular Biology

Protection of Momordica charantia polysaccharide against intracerebral hemorrhage-induced brain injury through JNK3 signaling pathway

Zhen-Zhen Duan et al.

JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION (2015)

Article Clinical Neurology

Microglial and macrophage polarization -new prospects for brain repair

Xiaoming Hu et al.

NATURE REVIEWS NEUROLOGY (2015)

Article Clinical Neurology

NLRP3 inflammasome contributes to inflammation after intracerebral hemorrhage

Qingyi Ma et al.

ANNALS OF NEUROLOGY (2014)

Article Clinical Neurology

Toll-like Receptor 2/4 Heterodimer Mediates Inflammatory Injury in Intracerebral Hemorrhage

Yan-Chun Wang et al.

ANNALS OF NEUROLOGY (2014)

Article Biochemistry & Molecular Biology

Effects of thrombin on the secondary cerebral injury of perihematomal tissues of rats after intracerebral hemorrhage

C. M. Liu et al.

GENETICS AND MOLECULAR RESEARCH (2014)

Article Medicine, General & Internal

Astragaloside IV Alleviates Early Brain Injury Following Experimental Subarachnoid Hemorrhage in Rats

Anwen Shao et al.

INTERNATIONAL JOURNAL OF MEDICAL SCIENCES (2014)

Article Medicine, General & Internal

Protective Effect of Quercetin against Oxidative Stress and Brain Edema in an Experimental Rat Model of Subarachnoid Hemorrhage

Yu-shu Dong et al.

INTERNATIONAL JOURNAL OF MEDICAL SCIENCES (2014)

Review Clinical Neurology

The role of iron in brain ageing and neurodegenerative disorders

Roberta Ward et al.

LANCET NEUROLOGY (2014)

Article Biochemistry & Molecular Biology

Sinomenine inhibits microglia activation and attenuates brain injury in intracerebral hemorrhage

Zhao Yang et al.

MOLECULAR IMMUNOLOGY (2014)

Article Clinical Neurology

(-)-Epicatechin protects hemorrhagic brain via synergistic Nrf2 pathways

Che-Feng Chang et al.

ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY (2014)

Review Biochemistry & Molecular Biology

Oxidative Stress in Ischemic Brain Damage: Mechanisms of Cell Death and Potential Molecular Targets for Neuroprotection

Hai Chen et al.

ANTIOXIDANTS & REDOX SIGNALING (2011)

Review Food Science & Technology

Potential health-promoting effects of astaxanthin: A high-value carotenoid mostly from microalgae

Jian-Ping Yuan et al.

MOLECULAR NUTRITION & FOOD RESEARCH (2011)

Article Endocrinology & Metabolism

Hemoglobin-induced oxidative stress contributes to matrix metalloproteinase activation and blood-brain barrier dysfunction in vivo

Masataka Katsu et al.

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2010)

Article Biochemistry & Molecular Biology

Curcumin Attenuates Vascular Inflammation and Cerebral Vasospasm After Subarachnoid Hemorrhage in Mice

Chandramohan Wakade et al.

ANTIOXIDANTS & REDOX SIGNALING (2009)

Article Chemistry, Analytical

Distribution and metabolism of gastrodin in rat brain

Qiao Wang et al.

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2008)

Article Chemistry, Analytical

Pharmacokinetics of gastrodin and its metabolite p-hydroxybenzyl alcohol in rat blood, brain and bile by microdialysis coupled to LC-MS/MS

Lei-Chwen Lin et al.

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2008)

Article Agriculture, Multidisciplinary

Pharmacokinetics of (-)-epigallocatechin-3-gallate in conscious and freely moving rats and its brain regional distribution

Lei-Chwen Lin et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2007)

Article Integrative & Complementary Medicine

Inhibitory effect of dauricine on inflammatory process following focal cerebral Ischemia/Reperfusion in rats

Xiao-Yan Yang et al.

AMERICAN JOURNAL OF CHINESE MEDICINE (2007)

Review Biochemistry & Molecular Biology

Antioxidant strategies in the treatment of stroke

I Margaill et al.

FREE RADICAL BIOLOGY AND MEDICINE (2005)

Article Neurosciences

Oxidative DNA injury after experimental intracerebral hemorrhage

T Nakamura et al.

BRAIN RESEARCH (2005)

Article Neurosciences

Hemin induces an iron-dependent, oxidative injury to human neuron-like cells

L Goldstein et al.

JOURNAL OF NEUROSCIENCE RESEARCH (2003)

Article Clinical Neurology

Heme oxygenase-1 gene therapy for prevention of vasospasm in rats

S Ono et al.

JOURNAL OF NEUROSURGERY (2002)