期刊
VACCINES
卷 10, 期 9, 页码 -出版社
MDPI
DOI: 10.3390/vaccines10091530
关键词
COVID-19; booster vaccination; adverse event; breast cancer; vaccine hesitancy
资金
- Clinical Research Program for West China Hospital, Sichuan University [2022HXFH021]
- National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University [Z20192011]
- Science and Technology Department of Sichuan Province [2021YJ0012]
- National Natural Science Foundation of China [32071284, 31971141]
The study conducted in China on breast cancer patients revealed that 55.2% had received a COVID-19 vaccine, with around 40% experiencing adverse events per dose. Vaccine hesitancy of 61.9% was observed among patients who had not fully received three doses of vaccine or boosters. Time since diagnosis was found to be the only variable associated with vaccine hesitancy.
Background: Patients with cancer show greater susceptibility and vulnerability to severe acute respiratory syndrome coronavirus 2 infection. However, data on the vaccination status among patients with breast cancer and any structured analysis of the factors influencing patients' decisions regarding vaccines are lacking. Methods: This cross-sectional study on patients with breast cancer in China was conducted from 1 June 2022, to 17 June 2022. Every participant completed an online questionnaire about their vaccination status and any adverse reactions, and a scale based on the Health Belief Model (HBM) to assess the vaccination status of respondents and their willingness to receive following doses or boosters. Results: Among the 1132 participants, 55.2% had received a COVID-19 vaccine. The incidence of adverse events per dose was around 40%. Vaccine hesitancy of 61.9% was observed among patients who had not fully received three doses of vaccine or boosters. The only variable found to be associated with vaccine hesitancy was time since diagnosis (p < 0.05). In the HBM scale, vaccine hesitancy was closely related to a low level of perceived susceptibility, a low level of perceived benefit, a high level of perceived barriers and a low level of agreement with doctors' advice. Conclusions: For patients with breast cancer, perceived susceptibility, benefits and barriers should be prioritized, and the advice from authoritative doctors is a vital cue to action.
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