☆ 4.7 Review

Renal Side Effects of COVID-19 Vaccination

VACCINES (2022)

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Review Medicine, General & Internal

New-onset IgA nephropathy following COVID-19 vaccination

Y. Ma et al.

Summary: The COVID-19 pandemic has caused significant economic and health damage globally, with vaccination being a key strategy to tackle severe illness and death. Recent reports of IgAN following COVID-19 vaccination have raised questions about their relationship. This review summarizes the latest clinical evidence on IgAN post-vaccination and proposes hypotheses for their pathogenesis.

QJM-AN INTERNATIONAL JOURNAL OF MEDICINE (2023)

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Review Clinical Neurology

Neurological side effects of SARS-CoV-2 vaccinations

Josef Finsterer

Summary: This review discusses the neurological side effects of SARS-CoV-2 vaccines, focusing on headache, Guillain-Barre syndrome (GBS), venous sinus thrombosis (VST), and transverse myelitis, which healthcare professionals should be vigilant about.

ACTA NEUROLOGICA SCANDINAVICA (2022)

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Article Urology & Nephrology

De novo or recurrent glomerulonephritis and acute tubulointerstitial nephritis after COVID-19 vaccination: A report of six cases from a single center

Taylor Schaubschlager et al.

Summary: Uncommon renal side effects, including the development or re-activation of various glomerular diseases, have been observed in some patients shortly after receiving COVID-19 vaccinations. Vigilance is necessary regarding these complications, although it is difficult to establish a causal relationship between COVID-19 vaccination and the onset/recurrence of kidney diseases. Importantly, all reported cases responded well to immunosuppressive treatment.

CLINICAL NEPHROLOGY (2022)

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Review Immunology

New-onset autoimmune phenomena post-COVID-19 vaccination

Yue Chen et al.

Summary: Autoimmune manifestations have been reported in response to certain COVID-19 vaccines, but it is still unclear whether there is a causal relationship. These reports can help guide the clinical assessment and management of autoimmune manifestations after vaccination.

IMMUNOLOGY (2022)

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Article Medicine, General & Internal

IgA Nephropathy with Gross Hematuria Following COVID-19 mRNA Vaccination

Yoshihito Nihei et al.

Summary: A case report highlights the development of Immunogloblin A nephropathy (IgAN) after administration of an mRNA vaccine. The biopsy showed mild changes and the symptoms improved without medication. Further studies are needed to investigate the association between mRNA vaccines and IgAN progression.

INTERNAL MEDICINE (2022)

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Letter Urology & Nephrology

New-onset class III lupus nephritis with multi-organ involvement after COVID-19 vaccination

Hyo Jeong Kim et al.

KIDNEY INTERNATIONAL (2022)

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Letter Urology & Nephrology

Relapsed ANCA associated vasculitis following Oxford AstraZeneca ChAdOx1-S COVID-19 vaccination: A case series of two patients

Rachel David et al.

NEPHROLOGY (2022)

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Letter Urology & Nephrology

Gross haematuria after mRNA COVID-19 vaccination in two patients with histological and clinical diagnosis of IgA nephropathy

Wai Kei Lo et al.

NEPHROLOGY (2022)

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Letter Urology & Nephrology

Report of two cases of minimal change disease following vaccination for COVID-19

Krishoban Baskaran et al.

NEPHROLOGY (2022)

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Letter Pediatrics

IgA nephropathy presenting as rapidly progressive glomerulonephritis following first dose of COVID-19 vaccine

Olivier Niel et al.

PEDIATRIC NEPHROLOGY (2022)

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Letter Pediatrics

Minimal change disease and acute interstitial nephritis following SARS-CoV-2 BNT162b2 vaccination

Pondtip Jongvilaikasem et al.

PEDIATRIC NEPHROLOGY (2022)

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Editorial Material Medicine, General & Internal

Newly diagnosed IgA nephropathy with gross haematuria following COVID-19 vaccination

T. Horino et al.

QJM-AN INTERNATIONAL JOURNAL OF MEDICINE (2022)

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Article Immunology

New-Onset Kidney Diseases after COVID-19 Vaccination: A Case Series

Jeong-Hoon Lim et al.

Summary: This study reports the clinical courses and histopathologic findings of new-onset kidney diseases after COVID-19 vaccination. The specific types of kidney diseases identified include IgA nephropathy, minimal change disease, thrombotic microangiopathy, and acute tubulointerstitial nephritis. Individualized treatment improved the outcomes of all patients. Clinicians should consider the possibility of vaccine-induced kidney diseases in patients with renal symptoms.

VACCINES (2022)

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Article Urology & Nephrology

De novo and relapsing necrotizing vasculitis after COVID-19 vaccination

Alexandre Fillon et al.

Summary: Five cases of severe necrotizing vasculitis following SARS-CoV-2 RNA-based vaccine were described, including four cases of relapsing ANCA vasculitis and one case of de novo PAN in a patient with quiescent chronic hepatitis B. Ten additional cases were reported in the French national pharmacovigilance database, with six patients having ANCA-associated vasculitis and four patients having PAN (with first symptoms occurring on average 19 days after vaccination). Five of these 10 patients developed kidney dysfunction. In conclusion, COVID-19 vaccines may be associated with de novo or recurrent ANCA vasculitis or PAN, and attention should be given to patients with known ANCA vasculitis or a history of hepatitis B infection.

CLINICAL KIDNEY JOURNAL (2022)

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Letter Urology & Nephrology

Reactivation of minimal change disease and IgA nephropathy after COVID-19 vaccination

Leanne Ca-Yin Leong et al.

CLINICAL KIDNEY JOURNAL (2022)

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Article Urology & Nephrology

An adolescent girl diagnosed with IgA nephropathy following the first dose of the COVID-19 vaccine

Mari Okada et al.

Summary: There is growing interest in cases of IgA nephropathy flare-up following COVID-19 vaccination. This report describes a 17-year-old girl who developed gross hematuria and proteinuria after receiving the first dose of the Pfizer vaccine. Although most cases occur after the second dose, this patient experienced symptoms even after the first dose.

CEN CASE REPORTS (2022)

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Letter Urology & Nephrology

A young adult with nephrotic syndrome following COVID-19 vaccination

Kei Nagai et al.

CEN CASE REPORTS (2022)

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Review Urology & Nephrology

New-onset pediatric nephrotic syndrome following Pfizer-BioNTech SARS-CoV-2 vaccination: a case report and literature review

Eriko Nakazawa et al.

Summary: New vaccines against SARS-CoV-2 have led to cases of nephrotic syndrome in some individuals, including children. With vaccination of children now underway in Japan, clinicians should be aware of the potential for nephrotic syndrome to develop following SARS-CoV-2 vaccination in both adults and children.

CEN CASE REPORTS (2022)

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Article Urology & Nephrology

Abrupt worsening of occult IgA nephropathy after the first dose of SARS-CoV-2 vaccination

Yoko Fujita et al.

Summary: A case report describes a patient who developed acute hematuria and nephrotic range proteinuria after receiving the first dose of SARS-CoV-2 vaccine, leading to a diagnosis of IgA nephropathy. This highlights the importance of monitoring kidney diseases after SARS-CoV-2 vaccination.

CEN CASE REPORTS (2022)

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Letter Urology & Nephrology

Need for symptom monitoring in IgA nephropathy patients post COVID-19 vaccination

Vinay Srinivasan et al.

CLINICAL NEPHROLOGY (2022)

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Letter Pediatrics

Focal segmental glomerulosclerosis recurrence in a young adult with kidney transplant after mRNA COVID-19 vaccination

Rosanna Fulchiero et al.

PEDIATRIC NEPHROLOGY (2022)

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Letter Pediatrics

Macroscopic hematuria in two children with IgA nephropathy remission following Pfizer COVID-19 vaccination

Tomohiro Udagawa et al.

PEDIATRIC NEPHROLOGY (2022)

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Letter Pediatrics

Two patients presenting IgA nephropathy after COVID-19 vaccination during a follow-up for asymptomatic hematuria

Kazumi Morisawa et al.

PEDIATRIC NEPHROLOGY (2022)

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Editorial Material Medicine, General & Internal

Minimal change glomerulonephritis following the second dose of the Moderna COVID-19 vaccine

H. J. Park et al.

QJM-AN INTERNATIONAL JOURNAL OF MEDICINE (2022)

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Letter Immunology

IgA nephropathy in a pediatric patient after receiving the first dose of Pfizer-BioNTech COVID-19 vaccine

Derar H. Abdel-Qader et al.

VACCINE (2022)

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Article Urology & Nephrology

IgA nephropathy relapse following COVID-19 vaccination treated with corticosteroid therapy: case report

Shota Watanabe et al.

Summary: Flare of IgA nephropathy (IgAN), causing significant acute kidney injury (AKI), has been observed in some cases following COVID-19 vaccination. Steroid therapy may lead to recovery. Close monitoring is needed to understand any adverse effects of the novel vaccine on IgAN relapse after vaccination.

BMC NEPHROLOGY (2022)

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Article Biotechnology & Applied Microbiology

Two adolescent cases of acute tubulointerstitial nephritis after second dose of COVID-19 mRNA vaccine

Jae Hong Choi et al.

Summary: Researchers report two cases of acute kidney injury in adolescents following the second dose of the Pfizer-BioNTech COVID-19 vaccine. These are the first pediatric cases of acute tubulointerstitial nephritis linked to the vaccine.

HUMAN VACCINES & IMMUNOTHERAPEUTICS (2022)

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Article Urology & Nephrology

Adult-onset nephrotic syndrome following coronavirus disease vaccination

Vivek Biradar et al.

Summary: A 22-year-old healthy man developed oedema and nephrotic syndrome 15 days after receiving the COVISHIELD COVID-19 vaccine, but achieved complete remission within 1 week after starting oral prednisolone therapy.

CLINICAL KIDNEY JOURNAL (2022)

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Review Immunology

New-Onset Acute Kidney Disease Post COVID-19 Vaccination

Yebei Li et al.

Summary: The emergence of acute kidney disease (AKD) following COVID-19 vaccination has raised concerns. This review summarizes hypotheses and pathogenesis of AKD caused by COVID-19 vaccines, aiming to assist clinical assessment and management of this condition.

VACCINES (2022)

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Review Immunology

Safety and Efficacy of the Common Vaccines against COVID-19

Ying Liu et al.

Summary: The COVID-19 pandemic has presented a global challenge to human health, and vaccination is crucial in controlling the spread of the disease. Different COVID-19 vaccines have varying levels of safety and efficacy. This article aims to conduct a systematic review to evaluate the safety and effectiveness of COVID-19 vaccines by analyzing clinical data and mass vaccination data. It is found that inactivated vaccines have lower adverse reactions, with an efficacy of approximately 60%, while adenovirus-vectored vaccines have an efficacy of 65%, and mRNA vaccines have an efficacy of 90%. RNA-based vaccines are considered promising and important during a pandemic, but further improvements are required, such as the need for booster doses to maintain immunity and the potential benefits of heterologous prime-boost immunization.

VACCINES (2022)

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Article Urology & Nephrology

IgA nephropathy with glomerular capillary IgA deposition following SARS-CoV-2 mRNA vaccination: a report of three cases

Shinya Yokote et al.

Summary: This study reported three cases of IgA nephropathy with glomerular capillary IgA deposition, which showed acute deterioration of urinalysis findings following SARS-CoV-2 mRNA vaccinations. Kidney biopsy showed severe glomerular lesions, indicating a potentially severe type of IgAN. Therefore, patients with de novo or relapsing IgAN showing significant capillary IgA deposition following SARS-CoV-2 vaccination should be monitored closely.

CEN CASE REPORTS (2022)

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Article Urology & Nephrology

A de novo case of minimal change disease following the first dose of the Moderna mRNA-1273 SARS-CoV-2 vaccine without relapse after the second dose

Reika Ikegami Mochizuki et al.

Summary: In recent times, cases of nephrotic syndrome following COVID-19 vaccination have been reported. A 25-year-old woman developed minimal change disease (MCD) after receiving the Moderna mRNA-1273 vaccine. Treatment with steroids led to complete remission, and she did not experience a relapse after receiving the second dose.

CEN CASE REPORTS (2022)

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Article Urology & Nephrology

De novo Minimal Change Disease in an Adolescent after Pfizer-BioNTech COVID-19 Vaccination: A Case Report

Eva Pella et al.

Summary: This is the first reported case of minimal change disease (MCD) in an adolescent after receiving the BNT162b2 COVID-19 vaccine, with complete remission following steroid treatment. The case provides additional support for the possible correlation between COVID-19 vaccination and the development of de novo and relapsing MCD.

CASE REPORTS IN NEPHROLOGY AND DIALYSIS (2022)

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Article Medicine, General & Internal

Acute interstitial nephritis after COVID-19 vaccination

Felicia S. C. Tan et al.

Summary: This is a case report of a woman in her 70s who developed acute kidney injury after receiving the AstraZeneca COVID-19 vaccine. Renal biopsy confirmed acute tubulointerstitial nephritis, and treatment with oral steroids led to significant improvement in her renal function. This suggests that the COVID-19 vaccine may have adverse effects, including kidney injury.

BMJ CASE REPORTS (2022)

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Article Medicine, General & Internal

Nephrotic syndrome with minimal change disease after the Pfizer-BioNTech COVID-19 vaccine: two cases

James Leon Hartley et al.

Summary: We report two cases of nephrotic syndrome with minimal change disease following Pfizer-BioNTech COVID-19 vaccination. The initial presentation, investigation, and management of these patients are discussed, along with a review of the current evidence base for vaccine-induced nephrotic syndrome.

BMJ CASE REPORTS (2022)

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Letter Surgery

De novo posttransplant membranous nephropathy following BNT162b2 mRNA COVID-19 vaccine in a kidney transplant recipient

Nathalie Chavarot et al.

AMERICAN JOURNAL OF TRANSPLANTATION (2022)

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Article Urology & Nephrology

Sibling cases of gross hematuria and newly diagnosed IgA nephropathy following SARS-CoV-2 vaccination

Yuri Uchiyama et al.

Summary: This study reports the first cases of siblings diagnosed with IgA nephropathy after receiving the second dose of SARS-CoV-2 vaccine, suggesting that the vaccine might trigger de novo IgA nephropathy or stimulate its relapse. It highlights the importance of understanding the immunological responses to the novel mRNA vaccines in patients with kidney diseases.

BMC NEPHROLOGY (2022)

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Article Medicine, General & Internal

De novo podocytopathy following moderna COVID-19 vaccine: A case report and racial disproportionality in adverse effect reports

Li-Yu Hong et al.

Summary: In this study, a case of de novo minimal change disease after the second dose of the Moderna COVID-19 vaccine is reported. The study suggests that ethnic differences may have limited influence on the prevalence, clinical presentation, and treatment outcomes of COVID-19 vaccine-associated glomerulonephritis.

FRONTIERS IN MEDICINE (2022)

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Article Medicine, General & Internal

New-onset crescent IgA nephropathy following the CoronaVac vaccine: A case report

Enrong Ran et al.

Summary: This article reports a case of crescentic immunoglobulin A nephropathy (IgAN) in a patient after receiving the Sinovac COVID-19 vaccine. This highlights the need for close monitoring of patients with glomerular diseases after COVID-19 vaccination.

MEDICINE (2022)

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Article Medicine, General & Internal

A Case Report of MPO-ANCA-Associated Vasculitis Following Heterologous mRNA1273 COVID-19 Booster Vaccination

Beop Chang Kim et al.

Summary: This case report presents a patient who developed new-onset renal-limited ANCA-associated vasculitis after receiving the mRNA 1273 (Moderna) vaccine. The patient was diagnosed with ANCA-associated pauci-immune crescentic glomerulonephritis following a kidney biopsy. Treatment with plasmapheresis, intravenous cyclophosphamide, and steroid pulse therapy resulted in improved renal function and constitutional symptoms.

JOURNAL OF KOREAN MEDICAL SCIENCE (2022)

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Article Medicine, General & Internal

Reactivation of minimal change disease after pfizer vaccine against COVID-19

Sindhu Marampudi et al.

Summary: This case describes the reactivation of minimal change disease (MCD) in a 54-year-old woman after receiving the Pfizer vaccine against COVID-19. The patient had a previous episode of MCD after receiving the influenza vaccine. The case highlights the importance of vigilance in patients with a history of MCD who are receiving the COVID-19 vaccine.

JOURNAL OF OSTEOPATHIC MEDICINE (2022)

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Article Urology & Nephrology

Th1 Cytokines Signature in 2 Cases of IgA Nephropathy Flare after mRNA-Based SARS-CoV-2 Vaccine: Exploring the Pathophysiology

Laura Martinez Valenzuela et al.

Summary: mRNA-based vaccines have been associated with IgA nephropathy flares in two previously diagnosed patients. The flares were more severe post-vaccination and one patient showed increased levels of IL-2 and TNF-alpha. Mechanistic studies are needed to understand the occurrence of these flares.

NEPHRON (2022)

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Article Urology & Nephrology

New Onset Biopsy-Proven Nephropathies after COVID Vaccination

Roberta Fenoglio et al.

Summary: This study analyzed cases of new-onset kidney disease following COVID-19 vaccination. Among the 17 patients, minimal change disease was the most common, followed by acute tubulointerstitial nephritis and membranous nephropathy. Some patients developed acute kidney injury, but renal function recovered after treatment.

AMERICAN JOURNAL OF NEPHROLOGY (2022)

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Letter Urology & Nephrology

Renal side effects of COVID-19 vaccines in patients with immunoglobulin A nephropathy

Jae Seok Park et al.

KIDNEY RESEARCH AND CLINICAL PRACTICE (2022)

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Article Urology & Nephrology

Acute interstitial nephritis after vaccination with BNT162b2

Sonja Rieckmann et al.

JOURNAL OF NEPHROLOGY (2022)

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Editorial Material Urology & Nephrology

Antineutrophil Cytoplasmic Autoantibody-Associated Glomerulonephritis Following the Pfizer-BioNTech COVID-19 Vaccine

Geoffrey K. Dube et al.

KIDNEY INTERNATIONAL REPORTS (2021)

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Letter Urology & Nephrology

Nephrotic Syndrome Following ChAdOx1 nCoV-19 Vaccine Against SARScoV-2

Y. J. Anupama et al.

KIDNEY INTERNATIONAL REPORTS (2021)

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Letter Urology & Nephrology

Report of Three Cases of Minimal Change Disease Following the Second Dose of mRNA SARS-CoV-2 COVID-19 Vaccine

Fadi Salem et al.

KIDNEY INTERNATIONAL REPORTS (2021)

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Letter Cardiac & Cardiovascular Systems

COVID-19 Vaccine and Myocarditis

Husam M. Salah et al.

AMERICAN JOURNAL OF CARDIOLOGY (2021)

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Article Urology & Nephrology

ANCA-Associated Vasculitis Following Pfizer-BioNTech COVID-19 Vaccine

Muhammad Tariq Shakoor et al.

Summary: Severe acute respiratory syndrome coronavirus 2 (SAR S-CoV-2) is still spreading worldwide, driving the largest vaccination campaign in human history. Although the vaccines have been found to be safe and effective, rare side effects continue to arise. A case of new-onset renal-limited ANCA-associated vasculitis (AAV) in a 78-year-old woman post Pfizer-BioNTech COVID-19 vaccination highlights the need for ongoing surveillance for similar complications.

AMERICAN JOURNAL OF KIDNEY DISEASES (2021)

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Article Urology & Nephrology

Minimal Change Disease With Severe Acute Kidney Injury Following the Oxford-AstraZeneca COVID-19 Vaccine: A Case Report

Simon Leclerc et al.

Summary: This case report describes a patient who developed minimal change disease (MCD) and severe acute kidney injury (AKI) following the Oxford-AstraZeneca COVID-19 vaccine. Treatment with glucocorticoids improved kidney function and proteinuria. Further research is needed to determine the association between MCD and COVID-19 vaccination.

AMERICAN JOURNAL OF KIDNEY DISEASES (2021)

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Review Biochemistry & Molecular Biology

Adaptive immunity to SARS-CoV-2 and COVID-19

Alessandro Sette et al.

Summary: The adaptive immune system, consisting of B cells, CD4(+) T cells, and CD8(+) T cells, plays varying roles in different viral infections and vaccines. Studies are showing that CD4(+) T cells, CD8(+) T cells, and neutralizing antibodies all play a part in controlling SARS-CoV-2 in COVID-19 cases, emphasizing the importance of understanding adaptive immunity in combating the disease.

CELL (2021)

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Letter Medicine, General & Internal

Nephrotic Syndrome After Vaccination Against COVID-19: Three New Cases From Germany

Harald Dormann et al.

DEUTSCHES ARZTEBLATT INTERNATIONAL (2021)

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Article Medicine, General & Internal

Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK

Merryn Voysey et al.

Summary: The ChAdOx1 nCoV-19 vaccine has been shown to have an acceptable safety profile and effectiveness against symptomatic COVID-19, with higher efficacy observed in the group that received a low dose followed by a standard dose.

LANCET (2021)

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Letter Urology & Nephrology

A case of ANCA-associated vasculitis after AZD1222 (Oxford-AstraZeneca) SARS-CoV-2 vaccination: casualty or causality?

Miguel Villa et al.

KIDNEY INTERNATIONAL (2021)

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Letter Urology & Nephrology

A case of membranous nephropathy following Pfizer-BioNTech mRNA vaccination against COVID-19

Yi Da et al.

KIDNEY INTERNATIONAL (2021)

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Letter Urology & Nephrology

Relapse of class V lupus nephritis after vaccination with COVID-19 mRNA vaccine

Katharina Tuschen et al.

KIDNEY INTERNATIONAL (2021)

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Letter Urology & Nephrology

Acute kidney injury with gross hematuria and IgA nephropathy after COVID-19 vaccination

Richard Plasse et al.

KIDNEY INTERNATIONAL (2021)

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Article Medicine, General & Internal

Safety and efficacy of an rAd26 and rAd5 vector-based heterologous prime-boost COVID-19 vaccine: an interim analysis of a randomised controlled phase 3 trial in Russia

Denis Y. Logunov et al.

Summary: The Gam-COVID-Vac vaccine showed 91.6% efficacy against COVID-19 in the phase 3 trial, with good safety and tolerability in a large cohort of participants.

LANCET (2021)

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Article Urology & Nephrology

Minimal change disease following the Moderna COVID-19 vaccine: first case report

Shaefiq Thappy et al.

Summary: This study reported the first case of MCD following the Moderna COVID-19 vaccine. The patient developed bilateral lower extremities swelling on day 7 post-vaccine and responded well to oral steroid treatment. Further studies are needed to determine the association between COVID-19 mRNA vaccines and MCD.

BMC NEPHROLOGY (2021)

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Article Urology & Nephrology

Minimal Change Disease Following the Pfizer-BioNTech COVID-19 Vaccine

Larissa Lebedev et al.

Summary: A 50-year-old man developed minimal change disease (MCD) with nephrotic syndrome and acute kidney injury (AKI) shortly after receiving his first dose of the Pfizer-BioNTech COVID-19 vaccine. Treatment with prednisone was initiated and kidney function gradually improved, eventually returning to normal. While the association between the vaccine and MCD is temporal and by exclusion, further reports are needed to evaluate the true incidence of this potential vaccine side effect.

AMERICAN JOURNAL OF KIDNEY DISEASES (2021)

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Letter Urology & Nephrology

An Additional Case of Minimal Change Disease Following the Pfizer-BioNTech COVID-19 Vaccine

Rutger J. Maas et al.

AMERICAN JOURNAL OF KIDNEY DISEASES (2021)

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Article Immunology

Case Report: ANCA-Associated Vasculitis Presenting With Rhabdomyolysis and Pauci-Immune Crescentic Glomerulonephritis After Pfizer-BioNTech COVID-19 mRNA Vaccination

Samy Hakroush et al.

Summary: Continuous monitoring of COVID-19 vaccine safety is crucial as vaccination programs expand worldwide, particularly in detecting rare adverse events associated with vaccination.

FRONTIERS IN IMMUNOLOGY (2021)

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Review Immunology

New-Onset and Relapsed Kidney Histopathology Following COVID-19 Vaccination: A Systematic Review

Henry H. L. Wu et al.

Summary: The systematic review identified various kidney pathologies following COVID-19 vaccination, with minimal change disease being the most frequent. Despite reported cases, there is no mortality and most patients recovered without long-term renal replacement therapy. Early biopsy for new-onset kidney disease and symptom monitoring for potential relapsed disease are recommended.

VACCINES (2021)

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Article Medicine, General & Internal

Case Report: Anti-neutrophil Cytoplasmic Antibody-Associated Vasculitis With Acute Renal Failure and Pulmonary Hemorrhage May Occur After COVID-19 Vaccination

Chien-Chou Chen et al.

Summary: This study describes a case of an elderly woman who developed anti-neutrophil cytoplasmic antibody-associated vasculitis with pulmonary renal syndrome approximately 3 weeks after receiving COVID-19 mRNA vaccination. Treatment with plasma exchange, systemic steroids, and anti-CD20 therapy led to resolution of pulmonary hemorrhage and improvement in renal function. Early examination of urinalysis and renal function may be crucial for identifying glomerulonephritis and acute renal failure in susceptible patients after COVID-19 vaccination.

FRONTIERS IN MEDICINE (2021)

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Letter Dermatology

Improving cultural competency and practicing cultural humility in dermatologic training: Skin of color education and board certification

Trisha Kaundinya et al.

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2021)

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Letter Urology & Nephrology

A case of gross hematuria and IgA nephropathy flare-up following SARS-CoV-2 vaccination

Shab E. Gul Rahim et al.

KIDNEY INTERNATIONAL (2021)

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Letter Urology & Nephrology

Minimal change disease and acute kidney injury following the Pfizer-BioNTech COVID-19 vaccine

Vivette D. D'Agati et al.

KIDNEY INTERNATIONAL (2021)

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Letter Urology & Nephrology

Relapse of primary membranous nephropathy after inactivated SARS-CoV-2 virus vaccination

Mehmet Fethullah Aydin et al.

KIDNEY INTERNATIONAL (2021)

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Letter Urology & Nephrology

Minimal change disease relapse following SARS-CoV-2 mRNA vaccine

Delphine Kervella et al.

KIDNEY INTERNATIONAL (2021)

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Article Urology & Nephrology

COVID-19 Vaccination and Glomerulonephritis

Nattawat Klomjit et al.

Summary: COVID-19 mRNA vaccine may lead to new or relapsing glomerulonephritis cases.

KIDNEY INTERNATIONAL REPORTS (2021)

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Article Medicine, General & Internal

Minimal change nephrotic syndrome four days after the administration of Pfizer-BioNTech COVID-19 vaccine-a new side effect or coincidence?

Mohammed Abdulgayoom et al.

Summary: The potential association between COVID vaccine and hepatic pyogenic abscess in polycystic hydronephrosis is still not fully established, but should be considered in cases post-vaccine administration.

CLINICAL CASE REPORTS (2021)

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Article Multidisciplinary Sciences

Cytotoxic T-lymphocyte elicited vaccine against SARS-CoV-2 employing immunoinformatics framework

Neeraj Kumar et al.

Summary: This study predicted highly efficacious CTL epitopes for a potential vaccine against COVID-19 through advanced immunoinformatics analysis, and molecular docking and dynamics simulation confirmed the strong immune response elicited by the CTL vaccine candidate.

SCIENTIFIC REPORTS (2021)

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Article Urology & Nephrology

A Case of Acute Interstitial Nephritis After Two Doses of the BNT162b2 SARS-CoV-2 Vaccine

Filipe S. Mira et al.

Summary: The development of COVID-19 vaccines has shown positive results, but also brought unexpected side effects. This case study describes a 45-year-old female patient who developed acute kidney injury after receiving the BNT162b2 SARS-CoV 2 vaccine, along with macular rash. Treatment with corticosteroids resulted in clinical improvement and recovery of kidney function, indicating that acute reactions to vaccines can occur. Healthcare providers and patients need to be aware of these potential side effects.

INTERNATIONAL JOURNAL OF NEPHROLOGY AND RENOVASCULAR DISEASE (2021)

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Letter Urology & Nephrology

Relapse of Minimal Change Disease Following the Pfizer-BioNTech COVID-19 Vaccine

Hirotaka Komaba et al.

AMERICAN JOURNAL OF KIDNEY DISEASES (2021)

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Article Urology & Nephrology

Minimal change disease following vaccination for SARS-CoV-2

Nicoletta Mancianti et al.

JOURNAL OF NEPHROLOGY (2021)

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Letter Urology & Nephrology

IgA nephropathy presenting as macroscopic hematuria in 2 pediatric patients after receiving the Pfizer COVID-19 vaccine

Christian Hanna et al.

KIDNEY INTERNATIONAL (2021)

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Letter Urology & Nephrology

Anti-GBM nephritis with mesangial IgA deposits after SARS-CoV-2 mRNA vaccination

Allan Sacker et al.

KIDNEY INTERNATIONAL (2021)

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Letter Urology & Nephrology

Is COVID-19 vaccination unmasking glomerulonephritis?

Hui Zhuan Tan et al.

KIDNEY INTERNATIONAL (2021)

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Letter Urology & Nephrology

Membranous nephropathy following anti-COVID-19 mRNA vaccination

Lorraine Gueguen et al.

KIDNEY INTERNATIONAL (2021)

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Letter Urology & Nephrology

Histologic correlates of gross hematuria following Moderna COVID-19 vaccine in patients with IgA nephropathy

Satoru Kudose et al.

KIDNEY INTERNATIONAL (2021)

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Letter Urology & Nephrology

ANCA glomerulonephritis after the Moderna COVID-19 vaccination

Arjun Sekar et al.

KIDNEY INTERNATIONAL (2021)

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Letter Urology & Nephrology

Gross hematuria following vaccination for severe acute respiratory syndrome coronavirus 2 in 2 patients with IgA nephropathy

Lavinia Negrea et al.

KIDNEY INTERNATIONAL (2021)

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Letter Urology & Nephrology

De novo vasculitis after mRNA-1273 (Moderna) vaccination

Manuel A. Anderegg et al.

KIDNEY INTERNATIONAL (2021)

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Letter Urology & Nephrology

Minimal change disease following the Moderna mRNA-1273 SARS-CoV-2 vaccine

Amy Holzworth et al.

KIDNEY INTERNATIONAL (2021)

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Letter Urology & Nephrology

Granulomatous vasculitis after the AstraZeneca anti-SARS-CoV-2 vaccine

Valentine Gillion et al.

KIDNEY INTERNATIONAL (2021)

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Letter Urology & Nephrology

Gross hematuria following SARS-CoV-2 vaccination in patients with IgA nephropathy

Peggy Perrin et al.

KIDNEY INTERNATIONAL (2021)

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Letter Urology & Nephrology

Relapse of minimal change disease following the AstraZeneca COVID-19 vaccine

Clare Morlidge et al.

KIDNEY INTERNATIONAL (2021)

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Letter Urology & Nephrology

New-onset systemic lupus erythematosus beginning as class V lupus nephritis after COVID-19 vaccination

Maria Fernanda Zavala-Miranda et al.

KIDNEY INTERNATIONAL (2021)

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Letter Urology & Nephrology

Letter regarding Minimal change disease relapse following SARS-CoV-2 mRNA vaccine

Nora Schwotzer et al.

KIDNEY INTERNATIONAL (2021)

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Letter Urology & Nephrology

Post-vaccinal minimal change disease

Jari Weijers et al.

KIDNEY INTERNATIONAL (2021)

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Article Multidisciplinary Sciences

Systems vaccinology of the BNT162b2 mRNA vaccine in humans

Prabhu S. Arunachalam et al.

Summary: The study found that vaccination with the Pfizer-BioNTech mRNA vaccine can induce immune responses against neutralizing antibodies and CD4, CD8 T cells of SARS-CoV-2. Booster vaccines can significantly enhance innate immune responses, and different innate pathways associated with CD8 T cells and neutralizing antibodies have been identified.

NATURE (2021)

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Article Multidisciplinary Sciences

Human IgG and IgA responses to COVID-19 mRNA vaccines

Adam Wisnewski et al.

Summary: Study on 4 subjects showed that COVID-19 mRNA vaccines effectively induce spike antigen-specific IgG and IgA, but there are marked differences in their persistence in serum.

PLOS ONE (2021)

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Editorial Material Medicine, General & Internal

IgA nephropathy flare-up following SARS-CoV-2 vaccination

T. Horino

QJM-AN INTERNATIONAL JOURNAL OF MEDICINE (2021)

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Article Urology & Nephrology

Nephrotic syndrome and acute kidney injury following CoronaVac anti-SARS-CoV-2 vaccine

Suat Unver et al.

Summary: This case study describes a 67-year-old female with Type 2 diabetes mellitus who developed nephrotic syndrome after receiving the CoronaVac vaccine. Treatment included antiproteinuric therapy and steroids, leading to improvement in kidney function.

CLINICAL KIDNEY JOURNAL (2021)

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Letter Urology & Nephrology

Minimal change disease following vaccination with CoronaVac

Ahmet Burak Dirim et al.

CLINICAL KIDNEY JOURNAL (2021)

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Article Urology & Nephrology

Minimal change disease soon after Pfizer-BioNTech COVID-19 vaccination

Seiji Kobayashi et al.

Summary: This case report describes the onset of minimal change disease (MCD) in a patient after receiving the second dose of the Pfizer-BioNTech mRNA vaccine for COVID-19. The patient achieved complete remission after treatment. While the definite causality between the vaccine and MCD is unclear, awareness of potential adverse effects of mRNA vaccines is crucial for determining their true incidence and frequency.

CLINICAL KIDNEY JOURNAL (2021)

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Review Urology & Nephrology

Minimal Change Disease After First Dose of Pfizer-BioNTech COVID-19 Vaccine: A Case Report and Review of Minimal Change Disease Related to COVID-19 Vaccine

Jessica Hanna et al.

Summary: Although severe complications are rare with COVID-19 vaccine, cases of nephrotic syndrome and acute kidney injury have been reported post-vaccination. Minimal change disease with acute tubular injury is a potential rare complication associated with Pfizer-BioNTech COVID-19 vaccine, which can be effectively managed with appropriate interventions.

CANADIAN JOURNAL OF KIDNEY HEALTH AND DISEASE (2021)

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Article Medicine, General & Internal

De-Novo Antineutrophil Cytoplasmic Antibody- Associated Vasculitis Following the mRNA-1273 (Moderna) Vaccine for COVID-19

Elio Junior Feghali et al.

Summary: The third case of ANCA-associated glomerulonephritis after receiving the mRNA-1273 COVID-19 vaccine was reported, showing acute kidney injury and sub nephrotic proteinuria. The patient achieved remission after successful treatment.

CUREUS JOURNAL OF MEDICAL SCIENCE (2021)

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Article Urology & Nephrology

IgA Nephropathy After SARS-CoV-2 Vaccination

Matthew Abramson et al.

Summary: This case report presents the first diagnosed case of IgA nephropathy following SARS-CoV-2 vaccination, suggesting a potential immunological mechanism and emphasizing the importance of understanding and monitoring immune responses.

KIDNEY MEDICINE (2021)

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Review Medicine, General & Internal

New-onset Nephrotic Syndrome after Janssen COVID-19 Vaccination: a Case Report and Literature Review

Jeong Hoon Lim et al.

Summary: A 51-year-old man developed nephrotic syndrome secondary to minimal change disease after receiving the Ad26.COV.2 (Janssen) vaccine. Clinicians should be cautious about potential renal effects of COVID-19 vaccines.

JOURNAL OF KOREAN MEDICAL SCIENCE (2021)

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Letter Rheumatology

Autoantibodies related to systemic autoimmune rheumatic diseases in severely ill patients with COVID-19

Panayiotis G. Vlachoyiannopoulos et al.

ANNALS OF THE RHEUMATIC DISEASES (2020)

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Letter Urology & Nephrology

Anti-glomerular basement membrane disease during the COVID-19 pandemic

Maria Prendecki et al.

KIDNEY INTERNATIONAL (2020)

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Article Multidisciplinary Sciences

COVID-19 vaccine BNT162b1 elicits human antibody and TH1 T cell responses

Ugur Sahin et al.

NATURE (2020)

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Review Immunology

Adenoviral Vector-Based Vaccine Platforms for Developing the Next Generation of Influenza Vaccines

Ekramy E. Sayedahmed et al.

VACCINES (2020)

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Editorial Material Urology & Nephrology

De Novo ANCA-Associated Vasculitis With Glomerulonephritis in COVID-19

Nupur N. Uppal et al.

KIDNEY INTERNATIONAL REPORTS (2020)

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Article Pediatrics

Tubulointerstitial Nephritis

Rebecca L. Ruebner et al.

PEDIATRIC CLINICS OF NORTH AMERICA (2019)

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Review Urology & Nephrology

Vaccine-Associated Kidney Diseases: A Narrative Review of the Literature

Chinmay Patel et al.

SAUDI JOURNAL OF KIDNEY DISEASES AND TRANSPLANTATION (2019)

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Review Immunology

Vaccine-induced autoimmunity: the role of molecular mimicry and immune crossreaction

Yahel Segal et al.

CELLULAR & MOLECULAR IMMUNOLOGY (2018)

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Review Biotechnology & Applied Microbiology

mRNA vaccines - a new era in vaccinology

Norbert Pardi et al.

NATURE REVIEWS DRUG DISCOVERY (2018)

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Review Urology & Nephrology

Epidemiology of IgA Nephropathy: A Global Perspective

Francesco Paolo Schena et al.

SEMINARS IN NEPHROLOGY (2018)

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Article Urology & Nephrology

Minimal Change Disease

Marina Vivarelli et al.

CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2017)

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Article Rheumatology

Viral RNA in the influenza vaccine may have contributed to the development of ANCA-associated vasculitis in a patient following immunisation

Lisa S. Jeffs et al.

CLINICAL RHEUMATOLOGY (2016)

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Article Medicine, General & Internal

IgA nephropathy

Kar Neng Lai et al.

NATURE REVIEWS DISEASE PRIMERS (2016)

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Review Urology & Nephrology

Pathogenesis of IgA nephropathy

Kar Neng Lai

NATURE REVIEWS NEPHROLOGY (2012)

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Article Rheumatology

Toll-like Receptor 2 Induces Th17 Myeloperoxidase Autoimmunity While Toll-like Receptor 9 Drives Th1 Autoimmunity in Murine Vasculitis

Shaun A. Summers et al.

ARTHRITIS AND RHEUMATISM (2011)

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