4.7 Review

Modifications of cellulose-based biomaterials for biomedical applications

出版社

FRONTIERS MEDIA SA
DOI: 10.3389/fbioe.2022.993711

关键词

cellulose; nanocellulose; hydrogel; biomaterial; biomedicine

资金

  1. National Institutes of Health
  2. National Science Foundation
  3. [R15GM140433]
  4. [P20GM139768]
  5. [MCB 1818346]

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This review highlights the advances and future prospects of cellulose as a biomaterial. It focuses on the applications of nanofibrillated, nanocrystalline, and bacterial cellulose as biomaterials in the field of biomedicine.
Cellulose is one of the most abundant organic compounds in nature and is available from diverse sources. Cellulose features tunable properties, making it a promising substrate for biomaterial development. In this review, we highlight advances in the physical processes and chemical modifications of cellulose that enhance its properties for use as a biomaterial. Three cellulosic products are discussed, including nanofibrillated, nanocrystalline, and bacterial cellulose, with a focus on how each may serve as a platform for the development of advanced cellulose-based biomaterials for Biomedical applications. In addition to associating mechanical and chemical properties of cellulosic materials to specific applications, a prospectus is offered for the future development of cellulose-based biomaterials for biomedicine.

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