4.7 Article

Super-enhancer associated core regulatory circuits mediate susceptibility to retinoic acid in neuroblastoma cells

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

JASPAR 2022: the 9th release of the open-access database of transcription factor binding profiles

Jaime A. Castro-Mondragon et al.

Summary: JASPAR is an open-access database containing manually curated, non-redundant transcription factor binding profiles across six taxonomic groups. The latest release introduces new profiles for plants, vertebrates, urochordates, and insects, as well as new tools for TFBS enrichment analysis and data access. The database can be accessed through various platforms, including the JASPAR website, RESTful API, R/Bioconductor data package, and a new Python package pyJASPAR.

NUCLEIC ACIDS RESEARCH (2022)

Review Oncology

MYCN Function in Neuroblastoma Development

Jorg Otte et al.

Summary: Dysregulated expression of the transcription factor MYCN is frequently detected in nervous system tumors such as childhood neuroblastoma and is a strong predictor of poor prognosis. Increased MYCN expression is an early event in these cancers, leading to a peculiar dysregulation of cells that exhibit embryonal or cancer stem-like qualities.

FRONTIERS IN ONCOLOGY (2021)

Article Multidisciplinary Sciences

Retinoic acid rewires the adrenergic core regulatory circuitry of childhood neuroblastoma

Mark W. Zimmerman et al.

Summary: Retinoids can reprogram enhancer landscape to down-regulate MYCN expression and establish a new retino-sympathetic CRC, causing proliferative arrest and inducing differentiation.

SCIENCE ADVANCES (2021)

Review Health Care Sciences & Services

Differentiating Neuroblastoma: A Systematic Review of the Retinoic Acid, Its Derivatives, and Synergistic Interactions

Nadiya Bayeva et al.

Summary: Neuroblastoma is a common pediatric tumor with challenges in treatment, but vitamin A derivative retinoic acid shows potential efficacy, prompting research on enhancing its anti-NB action and exploring synergy with other drugs.

JOURNAL OF PERSONALIZED MEDICINE (2021)

Article Genetics & Heredity

Genome scans of facial features in East Africans and cross-population comparisons reveal novel associations

Chenxing Liu et al.

Summary: Genetic factors play a crucial role in shaping human facial features, with shared and population-specific genetic contributions to normal-range facial variation observed in Tanzanian children compared to Europeans. 20 genomic regions associated with facial shape were identified in Tanzanian children, 10 of which overlapped with Europeans, indicating some shared genetic basis for human facial shape across populations. Additionally, unique genetic associations and differing shared signals were found, suggesting both common and distinct genetic architecture of facial variation among populations.

PLOS GENETICS (2021)

Review Oncology

Targeting the DNA Damage Response for the Treatment of High Risk Neuroblastoma

Harriet E. D. Southgate et al.

FRONTIERS IN ONCOLOGY (2020)

Review Pharmacology & Pharmacy

Targeting Super-Enhancers as a Therapeutic Strategy for Cancer Treatment

Yi He et al.

FRONTIERS IN PHARMACOLOGY (2019)

Article Multidisciplinary Sciences

A NOTCH feed-forward loop drives reprogramming from adrenergic to mesenchymal state in neuroblastoma

Tim van Groningen et al.

NATURE COMMUNICATIONS (2019)

Article Biochemistry & Molecular Biology

Super-enhancers in transcriptional regulation and genome organization

Xi Wang et al.

NUCLEIC ACIDS RESEARCH (2019)

Review Biochemistry & Molecular Biology

Why Differentiation Therapy Sometimes Fails: Molecular Mechanisms of Resistance to Retinoids

Petr Chlapek et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Review Pediatrics

High-Risk Neuroblastoma Treatment Review

Valeria Smith et al.

CHILDREN-BASEL (2018)

Review Biochemistry & Molecular Biology

WNT signaling, the development of the sympathoadrenal-paraganglionic system and neuroblastoma

Juergen Becker et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2018)

Review Cell Biology

Neuroblastoma pathogenesis: deregulation of embryonic neural crest development

Julie A. Tomolonis et al.

CELL AND TISSUE RESEARCH (2018)

Article Genetics & Heredity

Neuroblastoma is composed of two super-enhancer-associated differentiation states

Tim van Groningen et al.

NATURE GENETICS (2017)

Article Genetics & Heredity

Heterogeneity of neuroblastoma cell identity defined by transcriptional circuitries

Valentina Boeva et al.

NATURE GENETICS (2017)

Article Medicine, General & Internal

Genetic Associations with Gestational Duration and Spontaneous Preterm Birth

G. Zhang et al.

NEW ENGLAND JOURNAL OF MEDICINE (2017)

Article Multidisciplinary Sciences

Combined epigenetic and differentiation-based treatment inhibits neuroblastoma tumor growth and links HIF2α to tumor suppression

Isabelle Westerlund et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Article Cell Biology

TGF-β Family Signaling in Neural and Neuronal Differentiation, Development, and Function

Emily A. Meyers et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2017)

Article Multidisciplinary Sciences

Data Descriptor: Transcriptomic profiling of 39 commonly-used neuroblastoma cell lines

Jo Lynne Harenza et al.

SCIENTIFIC DATA (2017)

Review Oncology

Super-Enhancer-Driven Transcriptional Dependencies in Cancer

Satyaki Sengupta et al.

TRENDS IN CANCER (2017)

Article Biochemistry & Molecular Biology

Models of human core transcriptional regulatory circuitries

Violaine Saint-Andre et al.

GENOME RESEARCH (2016)

Article Multidisciplinary Sciences

Differentiation of the SH-SY5Y Human Neuroblastoma Cell Line

Mackenzie M. Shipley et al.

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2016)

Article Medicine, General & Internal

Neuroblastoma

Katherine K. Matthay et al.

NATURE REVIEWS DISEASE PRIMERS (2016)

Review Medicine, Research & Experimental

Neuroblastoma: Molecular Pathogenesis and Therapy

Chrystal U. Louis et al.

ANNUAL REVIEW OF MEDICINE, VOL 66 (2015)

Review Biochemistry & Molecular Biology

Retinoic acid signaling and neuronal differentiation

Amanda Janesick et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2015)

Article Biochemistry & Molecular Biology

THZ1 Reveals Roles for Cdk7 in Co-transcriptional Capping and Pausing

Kyle A. Nilson et al.

MOLECULAR CELL (2015)

Article Biochemistry & Molecular Biology

CDK7 Inhibition Suppresses Super-Enhancer-Linked Oncogenic Transcription in MYCN-Driven Cancer

Edmond Chipumuro et al.

Article Biochemistry & Molecular Biology

Retinoic Acid and Histone Deacetylases Regulate Epigenetic Changes in Embryonic Stem Cells

Alison M. Urvalek et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2014)

Article Biochemistry & Molecular Biology

A NOTCH 1-driven MYC enhancer promotes T cell development, transformation and acute lymphoblastic leukemia

Daniel Herranz et al.

NATURE MEDICINE (2014)

Article Biotechnology & Applied Microbiology

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

Michael I. Love et al.

GENOME BIOLOGY (2014)

Review Medicine, Research & Experimental

The role of aldehyde dehydrogenase (ALDH) in cancer drug resistance

Radoslaw Januchowski et al.

BIOMEDICINE & PHARMACOTHERAPY (2013)

Article Biochemistry & Molecular Biology

Selective Inhibition of Tumor Oncogenes by Disruption of Super-Enhancers

Jakob Loven et al.

Article Biochemistry & Molecular Biology

Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes

Warren A. Whyte et al.

Article Biochemistry & Molecular Biology

Super-Enhancers in the Control of Cell Identity and Disease

Denes Hnisz et al.

Review Oncology

Neuroblastoma: developmental biology, cancer genomics and immunotherapy

Nai-Kong V. Cheung et al.

NATURE REVIEWS CANCER (2013)

Review Medicine, Research & Experimental

Retinoids in Pediatric Onco-Hematology: the Model of Acute Promyelocytic Leukemia and Neuroblastoma

Riccardo Masetti et al.

ADVANCES IN THERAPY (2012)

Review Biochemistry & Molecular Biology

Physiological insights into all-trans-retinoic acid biosynthesis

Joseph L. Napoli

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2012)

Article Multidisciplinary Sciences

Differential oestrogen receptor binding is associated with clinical outcome in breast cancer

Caryn S. Ross-Innes et al.

NATURE (2012)

Letter Biochemical Research Methods

ChromHMM: automating chromatin-state discovery and characterization

Jason Ernst et al.

NATURE METHODS (2012)

Article Biochemical Research Methods

Fast gapped-read alignment with Bowtie 2

Ben Langmead et al.

NATURE METHODS (2012)

Article Biotechnology & Applied Microbiology

Differential expression analysis for sequence count data

Simon Anders et al.

GENOME BIOLOGY (2010)

Article Cell Biology

Cooperation between the Hic1 and Ptch1 tumor suppressors in medulloblastoma

Kimberly J. Briggs et al.

GENES & DEVELOPMENT (2008)

Article Biotechnology & Applied Microbiology

Model-based Analysis of ChIP-Seq (MACS)

Yong Zhang et al.

GENOME BIOLOGY (2008)

Review Neurosciences

Retinoic acid in the development, regeneration and maintenance of the nervous system

Malcolm Maden

NATURE REVIEWS NEUROSCIENCE (2007)

Article Biochemistry & Molecular Biology

Impaired retinoic acid (RA) signal leads to RARβ2 epigenetic silencing and RA resistance

MQ Ren et al.

MOLECULAR AND CELLULAR BIOLOGY (2005)

Article Biochemistry & Molecular Biology

Core transcriptional regulatory circuitry in human embryonic stem cells

LA Boyer et al.

Article Medicine, Research & Experimental

Neuroblastoma cells with overexpressed MYCN retain their capacity to undergo neuronal differentiation

A Edsjö et al.

LABORATORY INVESTIGATION (2004)

Article Oncology

Cellular retinol-binding protein expression and breast cancer

YS Kuppumbatti et al.

JOURNAL OF THE NATIONAL CANCER INSTITUTE (2000)