4.7 Article

Transplanted hair follicle mesenchymal stem cells alleviated small intestinal ischemia-reperfusion injury via intrinsic and paracrine mechanisms in a rat model

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Medicine, Research & Experimental

Novel biomarkers for acute respiratory distress syndrome: genetics, epigenetics and transcriptomics

Fei Zheng et al.

Summary: Acute respiratory distress syndrome (ARDS) is a severe lung injury disease caused by multiple clinical factors. Recent research suggests that genomic-based and transcriptomic-based biomarkers may predict the risk and outcomes of ARDS, and provide new therapeutic targets.

BIOMARKERS IN MEDICINE (2022)

Review Medicine, General & Internal

Oxidative Stress in Intestinal Ischemia-Reperfusion

Guangyao Li et al.

Summary: Intestinal ischemia-reperfusion (II/R) injury not only affects the intestine itself, but can also lead to damage of distant tissues and organs. Oxidative stress plays a crucial role in the pathogenesis of II/R injury, and various signaling pathways have different effects on II/R injury.

FRONTIERS IN MEDICINE (2022)

Review Cell & Tissue Engineering

Aging of intestinal stem cells

Kodandaramireddy Nalapareddy et al.

Summary: The intestine relies on stem cell function for maintaining tissue homeostasis. Aging results in changes to the intestinal architecture and a decline in the regenerative capacity of the intestine, mainly due to a decline in intestinal stem cell function. This review summarizes the mechanisms of aging in intestinal stem cells and their connection to extrinsic factors, and introduces recent approaches to attenuate or revert the aging process.

STEM CELL REPORTS (2022)

Article Microbiology

Lactobacillus murinus alleviate intestinal ischemia/reperfusion injury through promoting the release of interleukin-10 from M2 macrophages via Toll-like receptor 2 signaling

Jingjuan Hu et al.

Summary: This study investigated the relationship between the gut microbiome and intestinal ischemia/reperfusion (I/R) injury. It found that Lactobacillus murinus can alleviate intestinal I/R injury in mice through macrophages, and this effect may be achieved by promoting the release of IL-10 from macrophages through TLR2. This study revealed a novel mechanism of intestinal I/R injury and provided a new therapeutic strategy for clinical practice.

MICROBIOME (2022)

Review Biochemistry & Molecular Biology

Characteristics and regulation of mesenchymal stem cell plasticity by the microenvironment - specific factors involved in the regulation of MSC plasticity

Liping Tan et al.

Summary: Mesenchymal stem cells (MSCs) have been extensively studied in the field of regenerative medicine and cell therapy due to their self-renewal, multilineage differentiation, and immune regulation capacities. This review summarizes the plasticity of MSCs in different diseases and tissue sources, as well as the microenvironmental factors and molecular mechanisms that regulate their plasticity.

GENES & DISEASES (2022)

Article Cardiac & Cardiovascular Systems

The Exosomal lncRNA KLF3-AS1 From Ischemic Cardiomyocytes Mediates IGF-1 Secretion by MSCs to Rescue Myocardial Ischemia-Reperfusion Injury

Gecai Chen et al.

Summary: The study demonstrated that exosomes derived from H/R-treated H9c2 cells induced MSCs to secrete IGF-1 to inhibit myocardial cell injury. Moreover, the exosomal lncRNA KLF3-AS1 was found to promote the secretion of IGF-1 from MSCs and increase cell viability. Additionally, the lncRNA KLF3-AS1 upregulated STAT5B expression to rescue myocardial cell injury in vivo and in vitro, suggesting a potential new direction for the treatment of myocardial I/R injury.

FRONTIERS IN CARDIOVASCULAR MEDICINE (2021)

Review Engineering, Biomedical

Effects of Mesenchymal Stem Cell-Derived Paracrine Signals and Their Delivery Strategies

Calvin Chang et al.

Summary: This review focuses on the bioactivity and secretome of mesenchymal stem cells, as well as the engineering approaches to tune the MSC secretome. It also discusses the recent advances in biomaterials-based therapeutic strategies for delivering MSCs and MSC-derived secretome in extracellular vesicles, along with their advantages and challenges.

ADVANCED HEALTHCARE MATERIALS (2021)

Review Cell & Tissue Engineering

Applications of Umbilical Cord Derived Mesenchymal Stem Cells in Au-toimmune and Immunological Disorders: From Literature to Clinical Practice

Bahareh Abbaspanah et al.

Summary: With the increasing demand for MSCs, alternative sources are being sought, with umbilical cord MSCs emerging as a potentially valuable option with fewer ethical issues.

CURRENT STEM CELL RESEARCH & THERAPY (2021)

Article Cell Biology

Administration of Nrf-2-Modified Hair-Follicle MSCs Ameliorates DSS-Induced Ulcerative Colitis in Rats

Lin Zhou et al.

Summary: The study found that Nrf-2 expressing HF-MSCs had a significant therapeutic effect in treating ulcerative colitis, providing a new potential treatment option for this disease.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2021)

Article Pediatrics

Cell death induction (extrinsic versus intrinsic apoptotic pathway) by intestinal ischemia-reperfusion injury in rats is time-depended

Yoav Ben-Shahar et al.

Summary: This study investigated the mechanism of intestinal cell apoptosis in a rat model of intestinal ischemia-reperfusion (IR). Short-term reperfusion (24 hours) resulted in increased cell apoptosis, while long-term reperfusion (48 hours) led to increased cell proliferation. Short-term reperfusion primarily regulated cell apoptosis through intrinsic apoptotic pathways, while long-term reperfusion mainly induced cell apoptosis through extrinsic apoptotic pathways.

PEDIATRIC SURGERY INTERNATIONAL (2021)

Article Medicine, General & Internal

The Angiogenic Potential of Mesenchymal Stem Cells from the Hair Follicle Outer Root Sheath

Vuk Savkovic et al.

Summary: Neovascularization is essential for successful tissue grafting, and mesenchymal stem cells from hair follicle outer root sheath (MSCORS) exhibit strong angiogenic potential for future applications in tissue engineering. Compared to adipose mesenchymal stem cells, MSCORS show higher differentiation efficiency and greater angiogenic potential in endothelial derivatives.

JOURNAL OF CLINICAL MEDICINE (2021)

Article Biochemistry & Molecular Biology

Translational Application of Fluorescent Molecular Probes for the Detection of Reactive Oxygen and Nitrogen Species Associated with Intestinal Reperfusion Injury

Gustavo Sampaio de Holanda et al.

Summary: Acute mesenteric ischemia and reperfusion injury is a complex and lethal mechanism involving disruption of cellular microcirculation and mitochondrial damage. Fluorescent molecular probes have been shown to be highly efficient in monitoring the concentrations and locations of ROS and RNS.

METABOLITES (2021)

Article Oncology

Remote ischemic post-conditioning alleviates ischemia/reperfusion-induced intestinal injury via the ERK signaling pathway-mediated RAGE/HMGB axis

Lei Mi et al.

Summary: The study demonstrated that remote ischemic post-conditioning (RIPOC) can attenuate the histopathological features of intestinal mucosa in intestinal I/R injury mouse models through the ERK pathway. RIPOC also showed significant antioxidant and anti-inflammatory effects mediated via the ERK pathway, while suppressing the NF-kappa B (p65)/NLRP3 inflammatory pathways in the intestinal I/R injury mouse models.

MOLECULAR MEDICINE REPORTS (2021)

Article Biochemistry & Molecular Biology

Antioxidant-Based Therapy Reduces Early-Stage Intestinal Ischemia-Reperfusion Injury in Rats

Gaizka Gutierrez-Sanchez et al.

Summary: The study found that nitroindazole has a preventive/protective effect against intestinal tissue damage in the early stages of intestinal ischemia-reperfusion injury (i-IRI), reducing the extent of damage, and showing significant effects in both 1 and 2-hour ischemia periods. More research is needed to better understand the molecular mechanisms underlying this phenomenon.

ANTIOXIDANTS (2021)

Review Biochemistry & Molecular Biology

Hopes and Limits of Adipose-Derived Stem Cells (ADSCs) and Mesenchymal Stem Cells (MSCs) in Wound Healing

Loubna Mazini et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Review Cell & Tissue Engineering

Human hair follicle-derived mesenchymal stem cells: Isolation, expansion, and differentiation

Bo Wang et al.

WORLD JOURNAL OF STEM CELLS (2020)

Article Cell & Tissue Engineering

Stem cell homing: From physiology to therapeutics

Jane L. Liesveld et al.

STEM CELLS (2020)

Review Biotechnology & Applied Microbiology

Therapeutic targeting of the angiopoietin-TIE pathway

Pipsa Saharinen et al.

NATURE REVIEWS DRUG DISCOVERY (2017)

Review Cell & Tissue Engineering

Concise Review: MSC Adhesion Cascade-Insights into Homing and Transendothelial Migration

Franziska Nitzsche et al.

STEM CELLS (2017)

Article Physiology

Ischemia/Reperfusion

Theodore Kalogeris et al.

COMPREHENSIVE PHYSIOLOGY (2017)

Review Gastroenterology & Hepatology

Life and death at the mucosal-luminal interface: New perspectives on human intestinal ischemia-reperfusion

Joep Grootjans et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2016)

Article Gastroenterology & Hepatology

Animal models of ischemia-reperfusion-induced intestinal injury: progress and promise for translational research

Liara M. Gonzalez et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2015)

Review Cell Biology

Unraveling intestinal stem cell behavior with models of crypt dynamics

Alexis J. Carulli et al.

INTEGRATIVE BIOLOGY (2014)

Article Cell & Tissue Engineering

Induced Pluripotent Stem Cells from Human Hair Follicle Mesenchymal Stem Cells

Yimei Wang et al.

STEM CELL REVIEWS AND REPORTS (2013)

Article Gastroenterology & Hepatology

Activation of two distinct Sox9-EGFP-expressing intestinal stem cell populations during crypt regeneration after irradiation

Laurianne Van Landeghem et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2012)

Review Gastroenterology & Hepatology

Insulin-like growth factor 1: common mediator of multiple enterotrophic hormones and growth factors

Sarah F. Bortvedt et al.

CURRENT OPINION IN GASTROENTEROLOGY (2012)

Article Gastroenterology & Hepatology

Sox9 expression marks a subset of CD24-expressing small intestine epithelial stem cells that form organoids in vitro

Adam D. Gracz et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2010)