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FRONTIERS IN IMMUNOLOGY (2022)
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JOURNAL OF BIOSCIENCES (2021)
Nucleolar localization of the Notch4 intracellular domain underpins its regulation of the cellular response to genotoxic stressors
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CELL DEATH DISCOVERY (2020)
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BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2019)
Sumoylation of Notch1 represses its target gene expression during cell stress
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Nucleolus as an emerging hub in maintenance of genome stability and cancer pathogenesis
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ONCOGENE (2018)
Acetylation-Dependent Regulation of Notch Signaling in Macrophages by SIRT1 Affects Sepsis Development
Xiaozhi Bai et al.
FRONTIERS IN IMMUNOLOGY (2018)
Reversible Notch1 acetylation tunes proliferative signalling in cardiomyocytes
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CARDIOVASCULAR RESEARCH (2018)
The lysine deacetylase Sirtuin 1 modulates the localization and function of the Notch1 receptor in regulatory T cells
Nimi Marcel et al.
SCIENCE SIGNALING (2017)
The lysine deacetylase Sirtuin 1 modulates the localization and function of the Notch1 receptor in regulatory T cells
Nimi Marcel et al.
SCIENCE SIGNALING (2017)
SIRT1 Enhances the Survival of Human Embryonic Stem Cells by Promoting DNA Repair
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STEM CELL REPORTS (2017)
The Canonical Notch Signaling Pathway: Structural and Biochemical Insights into Shape, Sugar, and Force
Rhett A. Kovall et al.
DEVELOPMENTAL CELL (2017)
Nucleolin and nucleophosmin: nucleolar proteins with multiple functions in DNA repair
Daniel D. Scott et al.
BIOCHEMISTRY AND CELL BIOLOGY (2016)
Nucleolar methyltransferase fibrillarin: Evolution of structure and functions
M. Y. Shubina et al.
BIOCHEMISTRY-MOSCOW (2016)
The Notch intracellular domain integrates signals from Wnt, Hedgehog, TGFβ/BMP and hypoxia pathways
Tilman Borggrefe et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2016)
NOTCH1 Inhibits Activation of ATM by Impairing the Formation of an ATM-FOXO3a-KAT5/Tip60 Complex
Marek Adamowicz et al.
CELL REPORTS (2016)
Phosphorylation-dependent regulation of Notch1 signaling: the fulcrum of Notch1 signaling
Hye-Jin Lee et al.
BMB REPORTS (2015)
Notch is a direct negative regulator of the DNA-damage response
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NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)
Site-specific methylation of Notch1 controls the amplitude and duration of the Notch1 response
Kerstin Hein et al.
SCIENCE SIGNALING (2015)
Mechanisms Regulating Protein Localization
Nicholas C. Bauer et al.
TRAFFIC (2015)
Notch is a direct negative regulator of the DNA-damage response
Jelena Vermezovic et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)
AKT and 14-3-3 Regulate Notch4 Nuclear Localization
Gopalakrishnan Ramakrishnan et al.
SCIENTIFIC REPORTS (2015)
DNA Damage Response in Neonatal and Adult Stromal Cells Compared With Induced Pluripotent Stem Cells
Stefanie Liedtke et al.
STEM CELLS TRANSLATIONAL MEDICINE (2015)
Principles of protein targeting to the nucleolus
Robert M. Martin et al.
NUCLEUS (2015)
Site-specific methylation of Notch1 controls the amplitude and duration of the Notch1 response
Kerstin Hein et al.
SCIENCE SIGNALING (2015)
Principles of protein targeting to the nucleolus
Robert M. Martin et al.
NUCLEUS (2015)
Nucleophosmin modulates stability, activity, and nucleolar accumulation of base excision repair proteins
Mattia Poletto et al.
MOLECULAR BIOLOGY OF THE CELL (2014)
Notch1 Signaling Antagonizes Transforming Growth Factor- b Pathway and Induces Apoptosis in Rabbit Trophoblast Stem Cells
Tao Tan et al.
STEM CELLS AND DEVELOPMENT (2014)
Nucleolin mediates nucleosome disruption critical for DNA double-strand break repair
Michael Goldstein et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Nucleolin Participates in DNA Double-Strand Break-Induced Damage Response through MDC1-Dependent Pathway
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PLOS ONE (2012)
Ubiquitination of Notch1 is regulated by MAML1-mediated p300 acetylation of Notch1
Anita E. Popko-Scibor et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
Notch1 and the activated NOTCH1 intracellular domain are expressed in differentiated trophoblast cells
Didem Pelin Sarikaya et al.
CELL BIOLOGY INTERNATIONAL (2011)
Hierarchical Phosphorylation within the Ankyrin Repeat Domain Defines a Phosphoregulatory Loop That Regulates Notch Transcriptional Activity
Prathibha Ranganathan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Acetylation-dependent regulation of endothelial Notch signalling by the SIRT1 deacetylase
Virginia Guarani et al.
NATURE (2011)
Topoisomerase IIα-dependent induction of a persistent DNA damage response in response to transient etoposide exposure
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MOLECULAR ONCOLOGY (2010)
Nemo-like kinase suppresses Notch signalling by interfering with formation of the Notch active transcriptional complex
Tohru Ishitani et al.
NATURE CELL BIOLOGY (2010)
Post-translational modifications in signal integration
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NATURE STRUCTURAL & MOLECULAR BIOLOGY (2010)
The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism
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CELL (2009)
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Mark E. Fortini
DEVELOPMENTAL CELL (2009)
SIRT1 regulates apoptosis and Nanog expression in mouse embryonic stem cells by controlling p53 subcellular localization
Myung-Kwan Han et al.
CELL STEM CELL (2008)
Down-regulation of Notch-dependent transcription by Akt in vitro
Jieun Song et al.
FEBS LETTERS (2008)
Lysine acetylation: Codified crosstalk with other posttranslational modifications
Xiang-Jiao Yang et al.
MOLECULAR CELL (2008)
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ONCOGENE (2008)
Human embryonic stem cells have enhanced repair of multiple forms of DNA damage
Scott Maynard et al.
STEM CELLS (2008)
Zinc-induced downregulation of Notch signaling is associated with cytoplasmic retention of Notch1-IC and RBP-Jk via PI3k-Akt signaling pathway
Sang-Hyun Baek et al.
CANCER LETTERS (2007)
Asparaginyl hydroxylation of the notch ankyrin repeat domain by factor inhibiting hypoxia-inducible factor
Mathew L. Coleman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
4-nitroquinoline-1-oxide induces the formation of cellular topoisomerase I-DNA cleavage complexes
Ze-Hong Miao et al.
CANCER RESEARCH (2006)
Survival signaling by Notch1: Mammalian target of rapamycin (mTOR)-dependent inhibition of p53
Sathish Kumar Mungamuri et al.
CANCER RESEARCH (2006)
Paradigms of Notch signaling in mammals
A Dumortier et al.
INTERNATIONAL JOURNAL OF HEMATOLOGY (2005)
p300 acts as a transcriptional coactivator for mammalian Notch-1
F Oswald et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
Essential roles for ankyrin repeat and transactivation domains in induction of T-cell leukemia by Notch1
JC Aster et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
Functional interaction between the mouse Notch1 intracellular region and histone acetyltransferases PCAF and GCN5
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JOURNAL OF BIOLOGICAL CHEMISTRY (2000)