4.7 Review

Assessing kidney development and disease using kidney organoids and CRISPR engineering

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Cell Biology

Modeling injury and repair in kidney organoids reveals that homologous recombination governs tubular intrinsic repair

Navin Gupta et al.

Summary: Kidneys have the capacity for intrinsic repair, but when overwhelmed, incomplete repair can lead to chronic kidney disease. Limited treatments exist due to the limited predictivity of animal studies. This study used kidney organoids to identify genes and pathways involved in intrinsic repair and discovered a potential therapeutic candidate that can prevent the progression of chronic kidney disease.

SCIENCE TRANSLATIONAL MEDICINE (2022)

Article Biochemistry & Molecular Biology

The Impact of Oxygen Availability and Multilineage Communication on Organoid Maturation

Philipp Woersdoerfer et al.

Summary: Oxygen supply plays a crucial role in embryonic development and organogenesis, essential for growth, differentiation, and maturation of organoids. Studies indicate that hypoxia-induced processes are significant in organoid cultures, and optimal oxygen supply leads to reduced cellular stress and improved tissue maturation.

ANTIOXIDANTS & REDOX SIGNALING (2021)

Review Cell Biology

Kidney Organoids and Tubuloids

Fjodor A. Yousef Yengej et al.

Article Biology

Asynchronous mixing of kidney progenitor cells potentiates nephrogenesis in organoids

Ashwani Kumar Gupta et al.

COMMUNICATIONS BIOLOGY (2020)

Article Urology & Nephrology

PKD1-Dependent Renal Cystogenesis in Human Induced Pluripotent Stem Cell-Derived Ureteric Bud/Collecting Duct Organoids

Shohei Kuraoka et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2020)

Article Biochemical Research Methods

Flow-enhanced vascularization and maturation of kidney organoids in vitro

Kimberly A. Homan et al.

NATURE METHODS (2019)

Article Biochemistry & Molecular Biology

Single-cell transcriptomics reveals gene expression dynamics of human fetal kidney development

Mazene Hochane et al.

PLOS BIOLOGY (2019)

Review Cell Biology

Kidney organoids: accurate models or fortunate accidents

Melissa H. Little et al.

GENES & DEVELOPMENT (2019)

Article Urology & Nephrology

A Toolbox to Characterize Human Induced Pluripotent Stem Cell-Derived Kidney Cell Types and Organoids

Jessica M. Vanslambrouck et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2019)

Article Multidisciplinary Sciences

Single cell census of human kidney organoids shows reproducibility and diminished off-target cells after transplantation

Ayshwarya Subramanian et al.

NATURE COMMUNICATIONS (2019)

Article Biochemical Research Methods

Evaluation of variability in human kidney organoids

Belinda Phipson et al.

NATURE METHODS (2019)

Article Genetics & Heredity

Single-cell analysis reveals congruence between kidney organoids and human fetal kidney

Alexander N. Combes et al.

GENOME MEDICINE (2019)

Review Immunology

The role of the immune system in kidney disease

J. Tecklenborg et al.

CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2018)

Article Developmental Biology

Cross-platform single cell analysis of kidney development shows stromal cells express Gdnf

Bliss Magella et al.

DEVELOPMENTAL BIOLOGY (2018)

Article Urology & Nephrology

Conserved and Divergent Molecular and Anatomic Features of Human and Mouse Nephron Patterning

Nils O. Lindstrom et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2018)

Article Biochemical Research Methods

Simultaneous reprogramming and gene editing of human fibroblasts

Sara E. Howden et al.

NATURE PROTOCOLS (2018)

Article Urology & Nephrology

The ERA-EDTA today and tomorrow: a progress document by the ERA-EDTA Council

Carmine Zoccali et al.

CLINICAL KIDNEY JOURNAL (2018)

Review Medicine, General & Internal

Chronic kidney disease

Angela C. Webster et al.

LANCET (2017)

Article Cell & Tissue Engineering

Gene-Edited Human Kidney Organoids Reveal Mechanisms of Disease in Podocyte Development

Yong Kyun Kim et al.

STEM CELLS (2017)

Article Cell & Tissue Engineering

Higher-Order Kidney Organogenesis from Pluripotent Stem Cells

Atsuhiro Taguchi et al.

CELL STEM CELL (2017)

Article Urology & Nephrology

Human Induced Pluripotent Stem Cell-Derived Podocytes Mature into Vascularized Glomeruli upon Experimental Transplantation

Sazia Sharmin et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2016)

Article Urology & Nephrology

Physiology of the Renal Interstitium

Michael Zeisberg et al.

CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2015)

Article Developmental Biology

Stromal Fat4 acts non-autonomously with Dchs1/2 to restrict the nephron progenitor pool

Mazdak Bagherie-Lachidan et al.

DEVELOPMENT (2015)

Article Cell Biology

A Synthetic Niche for Nephron Progenitor Cells

Aaron C. Brown et al.

DEVELOPMENTAL CELL (2015)

Article Biotechnology & Applied Microbiology

Nephron organoids derived from human pluripotent stem cells model kidney development and injury

Ryuji Morizane et al.

NATURE BIOTECHNOLOGY (2015)

Article Biochemical Research Methods

Highly efficient Cas9-mediated transcriptional programming

Alejandro Chavez et al.

NATURE METHODS (2015)

Review Urology & Nephrology

Early chronic kidney disease: diagnosis, management and models of care

Olivier J. Wouters et al.

NATURE REVIEWS NEPHROLOGY (2015)

Article Multidisciplinary Sciences

Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids

Benjamin S. Freedman et al.

NATURE COMMUNICATIONS (2015)

Review Urology & Nephrology

Lineage-tracing methods and the kidney

Benjamin D. Humphreys et al.

KIDNEY INTERNATIONAL (2014)

Review Urology & Nephrology

Defining the Acute Kidney Injury and Repair Transcriptome

Sanjeev Kumar et al.

SEMINARS IN NEPHROLOGY (2014)

Review Urology & Nephrology

Directed Differentiation of Pluripotent Stem Cells to Kidney Cells

Albert Q. Lam et al.

SEMINARS IN NEPHROLOGY (2014)

Article Biochemistry & Molecular Biology

CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes

Luke A. Gilbert et al.

Editorial Material Urology & Nephrology

What can tubular progenitor cultures teach us about kidney regeneration?

Paola Romagnani et al.

KIDNEY INTERNATIONAL (2013)

Article Urology & Nephrology

Human embryonic stem cells differentiate into functional renal proximal tubular-like cells

Karthikeyan Narayanan et al.

KIDNEY INTERNATIONAL (2013)

Review Urology & Nephrology

Renal progenitors: an evolutionary conserved strategy for kidney regeneration

Paola Romagnani et al.

NATURE REVIEWS NEPHROLOGY (2013)

Article Multidisciplinary Sciences

Monitoring and robust induction of nephrogenic intermediate mesoderm from human pluripotent stem cells

Shin-Ichi Mae et al.

NATURE COMMUNICATIONS (2013)

Review Urology & Nephrology

Reprogramming the kidney: a novel approach for regeneration

Caroline E. Hendry et al.

KIDNEY INTERNATIONAL (2012)

Article Multidisciplinary Sciences

The Directed Differentiation of Human iPS Cells into Kidney Podocytes

Bi Song et al.

PLOS ONE (2012)

Article Physiology

The limitations of renal epithelial cell line HK-2 as a model of drug transporter expression and function in the proximal tubule

Sarah E. Jenkinson et al.

PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2012)

Article Cell Biology

Mammalian Kidney Development: Principles, Progress, and Projections

Melissa H. Little et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2012)

Article Anatomy & Morphology

Expression of Metanephric Nephron-Patterning Genes in Differentiating Mesonephric Tubules

K. M. Georgas et al.

DEVELOPMENTAL DYNAMICS (2011)

Review Pediatrics

Human nephron number: implications for health and disease

John F. Bertram et al.

PEDIATRIC NEPHROLOGY (2011)

Article Developmental Biology

Non-cell-autonomous retinoid signaling is crucial for renal development

Carolina Rosselot et al.

DEVELOPMENT (2010)

Article Urology & Nephrology

Glomerular Structure and Function Require Paracrine, Not Autocrine, VEGF-VEGFR-2 Signaling

Karen Sison et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2010)

Article Transplantation

Glomerular and proximal tubule cysts as early manifestations of Pkd1 deletion

Ali K. Ahrabi et al.

NEPHROLOGY DIALYSIS TRANSPLANTATION (2010)

Article Urology & Nephrology

Podocyte-Specific Loss of Functional MicroRNAs Leads to Rapid Glomerular and Tubular Injury

Jacqueline Ho et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2008)

Article Urology & Nephrology

Podocyte-Selective Deletion of Dicer Induces Proteinuria and Glomerulosclerosis

Shaolin Shi et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2008)

Correction Developmental Biology

A high-resolution anatomical ontology of the developing murine genitourinary tract (vol 7, pg 680, 2007)

Melissa H. Little et al.

GENE EXPRESSION PATTERNS (2007)

Article Biochemistry & Molecular Biology

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

Kazutoshi Takahashi et al.

Review Urology & Nephrology

Podocytes in culture: past, present, and future

S. J. Shankland et al.

KIDNEY INTERNATIONAL (2007)

Article Cell Biology

In vitro differentiation of murine embryonic stem cells toward a renal lineage

Stephen J. Bruce et al.

DIFFERENTIATION (2007)

Article Urology & Nephrology

Mouse embryonic stem cell-derived embryoid bodies generate progenitors that integrate long term into renal proximal tubules in vivo

Cecile Vigneau et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2007)

Article Urology & Nephrology

Nephrogenesis is induced by partial nephrectomy in the elasmobranch Leucoraja erinacea

M Elger et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2003)

Article Urology & Nephrology

Stem cells in the kidney

Q Al-Awqati et al.

KIDNEY INTERNATIONAL (2002)