期刊
OPEN FORUM INFECTIOUS DISEASES
卷 9, 期 10, 页码 -出版社
OXFORD UNIV PRESS INC
DOI: 10.1093/ofid/ofac526
关键词
COVID-19; host biomarker; prognosis
资金
- Medecins Sans Frontieres India
- Wellcome Trust [220211, 215604/Z/19/Z]
- Wellcome Trust/Royal Society Sir Henry Dale Fellowship [211182/Z/18/Z]
- Wellcome Trust [215604/Z/19/Z] Funding Source: Wellcome Trust
Efficient resource allocation is crucial for effective pandemic response, and host biomarkers can predict clinical outcomes in patients with COVID-19.
Efficient resource allocation is essential for effective pandemic response. We measured host biomarkers in 420 patients presenting with moderate coronavirus disease 2019 and found that different biomarkers predict distinct clinical outcomes. Interleukin (IL)-1ra, IL-6, IL-10, and IL-8 exhibit dose-response relationships with subsequent disease progression and could potentially be useful for multiple use-cases.
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