4.7 Article

Microfluidic-Based Formulation of Essential Oils-Loaded Chitosan Coated PLGA Particles Enhances Their Bioavailability and Nematocidal Activity

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Chemistry, Applied

Geographical variation of the chemical composition in essential oils extracted from SardinianSalvia verbenaca

Alberto Mannu et al.

Summary: The study found significant differences in the chemical composition of Salvia verbenaca grown in different geographical locations, with variations being attributed to geography and altitude. The chemical composition of the plants was mainly concentrated in oxygenated monoterpenes, monoterpene hydrocarbons, sesquiterpenes, and other compounds, which were affected by sampling site.

NATURAL PRODUCT RESEARCH (2022)

Article Nanoscience & Nanotechnology

Microfluidic mixing system for precise PLGA-PEG nanoparticles size control

Sara Gimondi et al.

Summary: Polymeric nanoparticles with well-controlled sizes were produced using a microfluidic device. The study explored the influence of several parameters on the synthesis process and evaluated the cytocompatibility and drug carrier efficacy of the nanoparticles. The results demonstrated the importance of nanoparticle size in drug encapsulation, release, and overall biological efficacy.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2022)

Article Biotechnology & Applied Microbiology

Research on the fate of polymeric nanoparticles in the process of the intestinal absorption based on model nanoparticles with various characteristics: size, surface charge and pro-hydrophobics

Shiqi Guo et al.

Summary: This study investigated the absorption of intestinal nanoparticles through different stages and found that the behavior of NPs in each stage varied due to differences in particle properties. Results showed that small size, low negative charge, and moderate hydrophilicity facilitated NPs passing through the small intestinal mucus layer, while appropriate size, positive surface charge, and hydrophobic properties helped NPs complete the process of transintestinal epithelial cell transport.

JOURNAL OF NANOBIOTECHNOLOGY (2021)

Review Pharmacology & Pharmacy

Essential Oils: Pharmaceutical Applications and Encapsulation Strategies into Lipid-Based Delivery Systems

Cinzia Cimino et al.

Summary: Essential oils have been studied for over 60 years, with a growing interest in recent decades due to a renewed focus on natural remedies. These oils have therapeutic properties that have been utilized for thousands of years, but their main limitations include poor hydrophobicity, high volatility, and potential toxicity risks. Strategies such as encapsulation within delivery systems have been successful in enhancing the bioavailability and stability of essential oils. Among these platforms, lipid-based delivery systems such as micro- and nanoemulsions, liposomes, solid lipid nanoparticles, and nanostructured lipid carriers are particularly promising.

PHARMACEUTICS (2021)

Editorial Material Infectious Diseases

Toward a New Future for Essential Oils

Edoardo Napoli et al.

ANTIBIOTICS-BASEL (2021)

Article Parasitology

Essential oil of Mentha pulegium induces anthelmintic effects and reduces parasite-associated oxidative stress in rodent model

Essia Sebai et al.

Summary: The study evaluated the anthelmintic and antioxidant properties of the volatile constituents of Mentha pulegium through in vitro and in vivo assays. The results showed significant nematicidal effects against Haemonchus contortus and antioxidant potential. Mentha pulegium oil demonstrated inhibition of egg hatch and paralysis of adult worms, as well as reduction in worm count and oxidative stress in mice infected with Heligmosomoides polygyrus. The plant also exhibited high antioxidant capacity in various in vitro assays.

EXPERIMENTAL PARASITOLOGY (2021)

Article Parasitology

Carvacryl acetate nanoencapsulated with chitosan/chicha gum exhibits reduced toxicity in mice and decreases the fecal egg count of sheep infected with gastrointestinal nematodes

Weibson P. P. Andre et al.

Summary: The study evaluated the efficacy of carvacryl acetate nanoencapsulated with biopolymers (nCVA) for controlling sheep gastrointestinal nematodes. The results showed that nCVA had a good control effect on sheep gastrointestinal nematodes with low toxicity.

PARASITOLOGY (2021)

Article Multidisciplinary Sciences

Investigating PLGA microparticle swelling behavior reveals an interplay of expansive intermolecular forces

Crystal E. Rapier et al.

Summary: This study analyzes the swelling behavior of unmodified PLGA microparticles in a high-throughput manner, providing insights into key factors influencing swelling and serving as a basis for predictive modeling.

SCIENTIFIC REPORTS (2021)

Article Immunology

The Development of Ovine Gastric and Intestinal Organoids for Studying Ruminant Host-Pathogen Interactions

David Smith et al.

Summary: The development of ovine epithelial organoids provides a valuable tool for studying interactions between pathogens and epithelial cells in sheep gastrointestinal infections. These organoids exhibit stable transcript profiles and can be cryopreserved, reducing the need for animal experimentation. Furthermore, they can be used for pathogen co-culture experiments, showcasing their potential utility in pathogen research.

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2021)

Article Pharmacology & Pharmacy

Nano-in-Micro-Particles Consisting of PLGA Nanoparticles Embedded in Chitosan Microparticles via Spray-Drying Enhances Their Uptake in the Olfactory Mucosa

Lena Marie Spindler et al.

Summary: The study demonstrates the potential of PLGA nanoparticles and chitosan NiMPs to utilize all three prominent intranasal delivery pathways to the brain and the CNS: transcellular, intracellular via neuronal cells, and paracellular transport. The findings suggest that these nanoparticles and microparticles hold promise for the treatment of neurological diseases.

FRONTIERS IN PHARMACOLOGY (2021)

Article Chemistry, Multidisciplinary

Synthesis and Functionalisation of Superparamagnetic Nano-Rods towards the Treatment of Glioblastoma Brain Tumours

Kinana Habra et al.

Summary: Complete removal of glioblastoma brain tumors is difficult, but embedding carnosine in an externally triggered nano-carrier has shown potential in inhibiting proliferation and activity of tumor cells, with possible implications for inhibiting metastasis and post-surgery monitoring via MRI.

NANOMATERIALS (2021)

Article Veterinary Sciences

The ATP bioluminescence assay: a new application and optimization for viability testing in the parasitic nematode Haemonchus contortus

Linh Thuy Nguyen et al.

Summary: The parasitic gastrointestinal nematode Haemonchus contortus causes economic losses in small ruminant livestock, and new therapies are needed. A novel viability testing method for adults and exsheathed third-stage larvae of H. contortus has been developed, which could serve as a complementary assay for screening new compounds with potential antinematode activity.

VETERINARY RESEARCH (2021)

Review Engineering, Biomedical

Recent advances in the formulation of PLGA microparticles for controlled drug delivery

Elena Lagreca et al.

PROGRESS IN BIOMATERIALS (2020)

Article Chemistry, Multidisciplinary

PLGA nanoparticle preparations by emulsification and nanoprecipitation techniques: effects of formulation parameters

Karol Yesenia Hernandez-Giottonini et al.

RSC ADVANCES (2020)

Article Biochemistry & Molecular Biology

In Vitro and In Vivo Effectiveness of Carvacrol, Thymol and Linalool against Leishmania infantum

Mohammad Reza Youssefi et al.

MOLECULES (2019)

Article Nanoscience & Nanotechnology

Preferential uptake of chitosan-coated PLGA nanoparticles by primary human antigen presenting cells

Veronica Duran et al.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2019)

Article Biochemistry & Molecular Biology

Profiles of the Essential Oils and Headspace Analysis of Volatiles from Mandragora autumnalis Growing Wild in Tunisia

Feten Arbia et al.

CHEMISTRY & BIODIVERSITY (2019)

Article Nanoscience & Nanotechnology

In vitro-in vivo evaluation of chitosan-PLGA nanoparticles for potentiated gastric retention and anti-ulcer activity of diosmin

Walaa Ebrahim Abd El Hady et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2019)

Article Food Science & Technology

Preparation, characterization, and antimicrobial activity of nanoemulsions incorporating citral essential oil

Wen-Chien Lu et al.

JOURNAL OF FOOD AND DRUG ANALYSIS (2018)

Article Biotechnology & Applied Microbiology

Mucoadhesive chitosan-coated PLGA nanoparticles for oral delivery of ferulic acid

Isabela Angeli de Lima et al.

ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY (2018)

Article Medicine, Research & Experimental

Novel docetaxel chitosan-coated PLGA/PCL nanoparticles with magnified cytotoxicity and bioavailability

Mohammad M. Badran et al.

BIOMEDICINE & PHARMACOTHERAPY (2018)

Article Chemistry, Medicinal

In vitro activity of the essential oil from Hesperozygis myrtoides on Rhipicephalus (Boophilus) microplus and Haemonchus contortus

Caroline V. V. Castilho et al.

REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY (2017)

Article Parasitology

Anthelmintic effect of thymol and thymol acetate on sheep gastrointestinal nematodes and their toxicity in mice

Weibson Paz Pinheiro Andre et al.

REVISTA BRASILEIRA DE PARASITOLOGIA VETERINARIA (2017)

Article Chemistry, Medicinal

In vitro activity of the essential oil from Hesperozygis myrtoides on Rhipicephalus (Boophilus) microplus and Haemonchus contortus

Caroline V. V. Castilho et al.

REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY (2017)

Review Pharmacology & Pharmacy

Pharmacological and Toxicological Properties of Eugenol

Solmaz Mohammadi Nejad et al.

TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES (2017)

Article Instruments & Instrumentation

Improved mucoadhesion and cell uptake of chitosan and chitosan oligosaccharide surface-modified polymer nanoparticles for mucosal delivery of proteins

Sathish Dyawanapelly et al.

DRUG DELIVERY AND TRANSLATIONAL RESEARCH (2016)

Article Engineering, Biomedical

pH-Responsive PLGA Nanoparticle for Controlled Payload Delivery of Diclofenac Sodium

Shalil Khanal et al.

JOURNAL OF FUNCTIONAL BIOMATERIALS (2016)

Review Food Science & Technology

Essential oils as antimicrobials in food systems - A review

Juliany Rivera Calo et al.

FOOD CONTROL (2015)

Review Chemistry, Multidisciplinary

Essential oil encapsulations: uses, procedures, and trends

Hamid Majeed et al.

RSC ADVANCES (2015)

Article Pharmacology & Pharmacy

Chitosan-Modified PLGA Nanoparticles with Versatile Surface for Improved Drug Delivery

Yichao Wang et al.

AAPS PHARMSCITECH (2013)

Article Parasitology

Activity of chitosan-encapsulated Eucalyptus staigeriana essential oil on Haemonchus contortus

Wesley Lyeverton Correia Ribeiro et al.

EXPERIMENTAL PARASITOLOGY (2013)

Review Biochemistry & Molecular Biology

Antioxidant and Anti-Inflammatory Activities of Essential Oils: A Short Review

Maria Graca Miguel

MOLECULES (2010)

Article Chemistry, Multidisciplinary

Uptake of FITC-chitosan nanoparticles by a549 cells

M Huang et al.

PHARMACEUTICAL RESEARCH (2002)