4.7 Article

Sugar-Triggered Burst Drug Releasing Poly-Lactic Acid (PLA) Microneedles and Its Fabrication Based on Solvent-Casting Approach

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Instruments & Instrumentation

From the laboratory to the end-user: a primary packaging study for microneedle patches containing amoxicillin sodium

Emma McAlister et al.

Summary: This research investigates the integrity of microneedle (MN) patches in different primary packaging under accelerated storage conditions, highlighting the importance of suitable primary packaging to prevent drug degradation.

DRUG DELIVERY AND TRANSLATIONAL RESEARCH (2021)

Article Engineering, Biomedical

Transdermal microneedles for the programmable burst release of multiple vaccine payloads

Khanh T. M. Tran et al.

Summary: The development of transdermal core-shell microneedle patches for preprogrammed release of vaccine payloads offers a potential alternative to reduce costs and improve global immunization campaigns. These patches, fabricated via additive manufacturing of polymer shells with different degradability kinetics, can effectively induce immune responses and provide protection against deadly bacteria over a longer period of time following a single administration.

NATURE BIOMEDICAL ENGINEERING (2021)

Article Chemistry, Multidisciplinary

Nitric Oxide Nanomotor Driving Exosomes-Loaded Microneedles for Achilles Tendinopathy Healing

Anlong Liu et al.

Summary: The detachable microneedle array designed in this study effectively delivered exosomes modified by a nitric oxide nanomotor to the injury site, enhancing the accumulation of exosomes and demonstrating significant potential in treating Achilles tendinopathy.

ACS NANO (2021)

Review Engineering, Biomedical

A systematic review of carbohydrate-based microneedles: current status and future prospects

Rupali S. Bhadale et al.

Summary: Carbohydrates play a crucial role in the fabrication of microneedles, allowing for tunable properties and functionalities for drug delivery and biological detection. This review provides a systematic discussion on various carbohydrates and their potential applications in biomedical devices.

JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE (2021)

Review Polymer Science

A Comprehensive Review of Microneedles: Types, Materials, Processes, Characterizations and Applications

Faisal Khaled Aldawood et al.

Summary: Drug delivery through the skin offers advantages such as avoiding hepatic metabolism and maintaining steady plasma concentration, but only a limited number of drugs with ideal properties can achieve therapeutic concentrations. Microneedles are a promising physical enhancement method to expand the spectrum of drugs for transdermal delivery. Different materials used for microneedles have implications for transdermal drug delivery, but challenges in sustained delivery, efficacy, cost-effective fabrication, and large-scale manufacturing remain. Microneedles have potential impact on drug delivery, vaccine delivery, disease diagnostics, and cosmetics applications.

POLYMERS (2021)

Review Chemistry, Multidisciplinary

Vesicular systems for dermal and transdermal drug delivery

Claire Richard et al.

Summary: Dermal/transdermal drug delivery is increasingly important for enhancing treatment activity and reducing toxicity by avoiding systemic absorption of drugs. This paper reviews the structure of the skin, parameters affecting drug diffusion, and strategies for improving dermal drug delivery, focusing on advanced carriers like vesicular systems. The review presents the state of the art and new trends in the field to optimize cutaneous and transcutaneous drug penetration.

RSC ADVANCES (2021)

Article Chemistry, Multidisciplinary

Built-In Active Microneedle Patch with Enhanced Autonomous Drug Delivery

Miguel Angel Lopez-Ramirez et al.

ADVANCED MATERIALS (2020)

Article Chemistry, Multidisciplinary

Dissolving undercut microneedle arrays for multicomponent cutaneous vaccination

Stephen C. Balmert et al.

JOURNAL OF CONTROLLED RELEASE (2020)

Article Biochemistry & Molecular Biology

Enzymatic Self-Biodegradation of Poly(L-lactic acid) Films by Embedded Heat-Treated and Immobilized Proteinase K

QiuYuan Huang et al.

BIOMACROMOLECULES (2020)

Review Pharmacology & Pharmacy

A review of recent advances in microneedle technology for transdermal drug delivery

Rigved Nagarkar et al.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2020)

Article Pharmacology & Pharmacy

Predicting Transdermal Fentanyl Delivery Using Mechanistic Simulations for Tailored Therapy

Thijs Defraeye et al.

FRONTIERS IN PHARMACOLOGY (2020)

Review Pharmacology & Pharmacy

The Current Status of Clinical Research Involving Microneedles: A Systematic Review

Seung-Yeon Jeong et al.

PHARMACEUTICS (2020)

Article Engineering, Biomedical

Rapidly separable microneedle patch for the sustained release of a contraceptive

Wei Li et al.

NATURE BIOMEDICAL ENGINEERING (2019)

Article Engineering, Environmental

Biocompatibility, biodegradation and excretion of polylactic acid (PLA) in medical implants and theranostic systems

Dana da Silva et al.

CHEMICAL ENGINEERING JOURNAL (2018)

Article Pharmacology & Pharmacy

In vitro and in vivo assessment of polymer microneedles for controlled transdermal drug delivery

Bo Zhi Chen et al.

JOURNAL OF DRUG TARGETING (2018)

Article Pharmacology & Pharmacy

Microneedles as Enhancer of Drug Absorption Through the Skin and Applications in Medicine and Cosmetology

Pablo Serrano-Castaneda et al.

JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES (2018)

Review Surgery

Microneedling: Where do we stand now? A systematic review of the literature

Lisa Ramaut et al.

JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY (2018)

Article Pharmacology & Pharmacy

Touch-actuated microneedle array patch for closed-loop transdermal drug delivery

Jingbo Yang et al.

DRUG DELIVERY (2018)

Review Chemistry, Multidisciplinary

Microneedles in the clinic

Shubhmita Bhatnagar et al.

JOURNAL OF CONTROLLED RELEASE (2017)

Review Nutrition & Dietetics

The Roles of Vitamin C in Skin Health

Juliet M. Pullar et al.

NUTRIENTS (2017)

Review Pharmacology & Pharmacy

Polylactic acid (PLA) controlled delivery carriers for biomedical applications

Betty Tyler et al.

ADVANCED DRUG DELIVERY REVIEWS (2016)

Article Chemistry, Multidisciplinary

Droplet-born air blowing: Novel dissolving microneedle fabrication

Jung Dong Kim et al.

JOURNAL OF CONTROLLED RELEASE (2013)

Review Pharmacology & Pharmacy

Biodegradation and biocompatibility of PLA and PLGA microspheres

James M. Anderson et al.

ADVANCED DRUG DELIVERY REVIEWS (2012)

Article Dermatology

Silicone migration and granuloma formation

Mary D. Altmeyer et al.

JOURNAL OF COSMETIC DERMATOLOGY (2009)

Article Engineering, Biomedical

Dissolving microneedles for transdermal drug delivery

Jeong W. Lee et al.

BIOMATERIALS (2008)

Review Pharmacology & Pharmacy

Microneedles and transdermal applications

Raja K. Sivamani et al.

EXPERT OPINION ON DRUG DELIVERY (2007)

Article Pharmacology & Pharmacy

How porosity and size affect the drug release mechanisms from PLIGA-based microparticles

D. Klose et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2006)

Article Chemistry, Multidisciplinary

Biodegradable polymer microneedles: Fabrication, mechanics and transdermal drug delivery

JH Park et al.

JOURNAL OF CONTROLLED RELEASE (2005)

Article Multidisciplinary Sciences

Microfabricated needles for transdermal delivery of macromolecules and nanoparticles: Fabrication methods and transport studies

DV McAllister et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Article Chemistry, Analytical

Solvent compatibility of poly(dimethylsiloxane)-based microfluidic devices

JN Lee et al.

ANALYTICAL CHEMISTRY (2003)

Article Pharmacology & Pharmacy

Dermal penetration of fentanyl: Inter- and intraindividual variations

RH Larsen et al.

PHARMACOLOGY & TOXICOLOGY (2003)

Review Dermatology

Effects of skin occlusion on percutaneous absorption: An overview

HB Zhai et al.

SKIN PHARMACOLOGY AND APPLIED SKIN PHYSIOLOGY (2001)