4.7 Article

Functional Outcomes Following Hip Replacement in Community-Dwelling Older Adults

期刊

JOURNAL OF CLINICAL MEDICINE
卷 11, 期 17, 页码 -

出版社

MDPI
DOI: 10.3390/jcm11175117

关键词

hip replacement; older adults; physical function

资金

  1. National Institute on Aging [U01AG029824, U19AG062682]
  2. National Cancer Institute at the US National Institutes of Health [334047, 1127060]
  3. National Health and Medical Research Council of Australia (NHMRC)
  4. Monash University
  5. Victorian Cancer Agency
  6. NHMRC Translating Research into Practice Fellowship [APP1168185]
  7. Royal Australian College of Physicians Fellows Career Development Fellowship
  8. NHMRC Investigator Grant [APP1194829]

向作者/读者索取更多资源

Hip replacement surgery can significantly improve physical function in older adults, and the degree of preoperative physical impairment is an important indicator for predicting surgical outcomes.
Uncertainty remains regarding the benefit of hip replacement in older adults in the context of age-related decline in physical function. This study aimed to examine the effect of hip replacement on functional outcomes and identify factors associated with clinically important improvement in physical function postoperatively in community-dwelling older adults. This cohort study was performed within the ASPREE trial, with 698 participants receiving hip replacement and 677 age- and sex-matched controls without knee or hip replacement during the trial drawn from 16,703 Australian participants aged >= 70 years. Health status (physical and mental component summary [PCS and MCS]) was assessed annually using the SF-12. Participants receiving hip replacement had significantly lower pre- and post-replacement PCS scores compared with controls (p < 0.0001). There was significant improvement in PCS score following hip replacement (mean change 4.9, 95%CI 4.0-5.7) but no change in controls (0.01, 95%CI -0.7-0.7). Following hip replacement, 46.7% of participants experienced clinically important improvement in PCS score, while 15.5% experienced worsened PCS score. Participants experiencing improved postoperative PCS score had significantly lower PCS and higher MCS scores preoperatively. The degree of preoperative physical function impairment was a significant indicator of older people most likely to benefit from hip replacement surgery.

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