4.7 Article

Intradermal vaccination of HPV-16 E6 synthetic peptides conjugated to an optimized Toll-like receptor 2 ligand shows safety and potent T cell immunogenicity in patients with HPV-16 positive (pre-)malignant lesions

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

Personal neoantigen vaccines induce persistent memory T cell responses and epitope spreading in patients with melanoma

Zhuting Hu et al.

Summary: Personal neoantigen peptide vaccines induce long-lasting T cell responses in melanoma patients, broadening the spectrum of tumor-specific cytotoxicity and resulting in diverse T cell clones with cytotoxic gene signatures.

NATURE MEDICINE (2021)

Review Oncology

Therapeutic cancer vaccines

Mansi Saxena et al.

Summary: Therapeutic cancer vaccines aim to induce tumor regression, eradicate minimal residual disease, establish lasting anti-tumor memory, and avoid non-specific or adverse reactions. However, challenges arise due to tumor-induced immunosuppression and immunoresistance, hindering the achievement of these goals.

NATURE REVIEWS CANCER (2021)

Article Cell Biology

Strong vaccine responses during chemotherapy are associated with prolonged cancer survival

Cornelis J. M. Melief et al.

SCIENCE TRANSLATIONAL MEDICINE (2020)

Article Chemistry, Medicinal

Self-Adjuvanting Cancer Vaccines from Conjugation-Ready Lipid A Analogues and Synthetic Long Peptides

Niels R. M. Reintjens et al.

JOURNAL OF MEDICINAL CHEMISTRY (2020)

Article Chemistry, Medicinal

Peptides conjugated to 2-alkoxy-8-oxo-adenine as potential synthetic vaccines triggering TLR7

Geoffroy P. P. Gential et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2019)

Article Oncology

Novel TLR2-binding adjuvant induces enhanced T cell responses and tumor eradication

Gijs G. Zom et al.

JOURNAL FOR IMMUNOTHERAPY OF CANCER (2018)

Article Multidisciplinary Sciences

An immunogenic personal neoantigen vaccine for patients with melanoma

Patrick A. Ott et al.

NATURE (2017)

Article Cell Biology

Vaccination during myeloid cell depletion by cancer chemotherapy fosters robust T cell responses

Marij J. Welters et al.

SCIENCE TRANSLATIONAL MEDICINE (2016)

Article Chemistry, Medicinal

N-Tetradecylcarbamyl Lipopeptides as Novel Agonists for Toll-like Receptor 2

Marian M. J. H. P. Willems et al.

JOURNAL OF MEDICINAL CHEMISTRY (2014)

Article Medicine, Research & Experimental

HPV16 synthetic long peptide (HPV16-SLP) vaccination therapy of patients with advanced or recurrent HPV16-induced gynecological carcinoma, a phase II trial

Mariette I. E. van Poelgeest et al.

JOURNAL OF TRANSLATIONAL MEDICINE (2013)

Review Immunology

Therapeutic vaccination against human papilloma virus induced malignancies

Sjoerd H. van der Burg et al.

CURRENT OPINION IN IMMUNOLOGY (2011)

Editorial Material Clinical Neurology

Vaccine provides new hope for patients with deadly brain cancer

[Anonymous]

FUTURE NEUROLOGY (2010)

Article Multidisciplinary Sciences

Success or failure of vaccination for HPV16-positive vulvar lesions correlates with kinetics and phenotype of induced T-cell responses

Marij J. P. Welters et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Medicine, General & Internal

Vaccination against HPV-16 Oncoproteins for Vulvar Intraepithelial Neoplasia.

Gemma G. Kenter et al.

NEW ENGLAND JOURNAL OF MEDICINE (2009)