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Underlying mechanisms of acupuncture therapy on polycystic ovary syndrome: Evidences from animal and clinical studies

期刊

FRONTIERS IN ENDOCRINOLOGY
卷 13, 期 -, 页码 -

出版社

FRONTIERS MEDIA SA
DOI: 10.3389/fendo.2022.1035929

关键词

acupuncture; animal studies; clinical studies; mechanism; polycystic ovary syndrome; review

资金

  1. Special Grant for Capital Health Research and Development
  2. National Natural Science Foundation of China
  3. Peking University Third Hospital Key Young Talents Training Program
  4. [2022-2-4098]
  5. [82174151]
  6. [BYSYFY2021032]

向作者/读者索取更多资源

PCOS is a common endocrine and metabolic disorder among women, and current treatments have unsatisfactory efficacy. Acupuncture has shown significant effectiveness in regulating hormone levels, promoting ovulation, and attenuating insulin resistance. However, the mechanisms of acupuncture therapy in treating PCOS have not been comprehensively studied and evaluated.
Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder among women of reproductive age. Current standard treatment includes lifestyle change, oral pharmacological agents, and surgical modalities. However, the efficacy of current therapies is less than satisfactory. Clinical evidence has shown that acupuncture is effective for regulating hormone levels, promoting ovulation, and attenuating insulin resistance in patients with PCOS. Acupuncture may affect the production of beta-endorphin, which may lead to gonadotropin-releasing hormone secretion and then affect ovulation, menstrual cycle, and fertility. The mechanism of acupuncture for patients with PCOS has not been comprehensively reviewed so far. Better understanding of the mechanisms of acupuncture would help popularize the use of acupuncture therapy for patients with PCOS. In this narrative review, we aimed to overview the potential mechanisms and evidence-based data of acupuncture on PCOS, and analyze the most frequently used acupoints based on animal and clinical studies. The results of this study will contribute to a better understanding of the current situation in this field.

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