期刊
FRONTIERS IN NEUROLOGY
卷 13, 期 -, 页码 -出版社
FRONTIERS MEDIA SA
DOI: 10.3389/fneur.2022.1022944
关键词
Parkinson's disease; cognitive impairment; dementia; high myopia; MRI; neuroimage; the visual system; neuroplasticity
资金
- Equipment Comprehensive Scientific Research Project of China
- [LB20201A010024]
Visual impairment and cognitive impairment are related to high myopia, but the specific pathogenesis and neural structure damage are not well understood.
Dementia and cognitive impairment (CIM) carry high levels of mortality. Visual impairment (VI) is linked with CIM risk. High myopia (HM) is a chronic disease frequently leading to irreversible blindness. Current opinion has shifted from retinal injury as the cause of HM to the condition being considered an eye-brain disease. However, the pathogenesis of this disease and the manner in which neural structures are damaged are poorly understood. This review comprehensively discusses the relationship between HM, the central nervous system, and CIM, together with the novel concept of three visual pathways, and possible research perspectives.
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