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Chicken DNA Sensing cGAS-STING Signal Pathway Mediates Broad Spectrum Antiviral Functions
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The emerging role of STING-dependent signaling on cell death
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STING-mediated disruption of calcium homeostasis chronically activates ER stress and primes T cell death
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Structural basis of STING binding with and phosphorylation by TBK1
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Autophagy induced by STING, an unnoticed and primordial function of cGAS
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Inflammatory-dependent Sting activation induces antiviral autophagy to limit zika virus in the Drosophila brain
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STING directly activates autophagy to tune the innate immune response
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Autophagy balances inflammation in innate immunity
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Attenuation of cGAS-STING signaling is mediated by a p62/SQSTM1-dependent autophagy pathway activated by TBK1
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Cutting Edge: Activation of STING in T Cells Induces Type I IFN Responses and Cell Death
Bridget Larkin et al.
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Trafficking-Mediated STING Degradation Requires Sorting to Acidified Endolysosomes and CanBe Targeted to Enhance Anti-tumor Response
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STING Senses Microbial Viability to Orchestrate Stress-Mediated Autophagy of the Endoplasmic Reticulum
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iLIR database: A web resource for LIR motif-containing proteins in eukaryotes
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Agonist-Mediated Activation of STING Induces Apoptosis in Malignant B Cells
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Mycobacterium bovis Induces Endoplasmic Reticulum Stress Mediated-Apoptosis by Activating IRF3 in a Murine Macrophage Cell Line
Yongyong Cui et al.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2016)
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MICROBIAL CELL (2016)
Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation
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TRIM30α Is a Negative-Feedback Regulator of the Intracellular DNA and DNA Virus-Triggered Response by Targeting STING
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Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy
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Cyclic Dinucleotides Trigger ULK1 (ATG1) Phosphorylation of STING to Prevent Sustained Innate Immune Signaling
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CELL (2013)
Host Restriction Factor SAMHD1 Limits Human T Cell Leukemia Virus Type 1 Infection of Monocytes via STING-Mediated Apoptosis
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STING-IRF3 pathway links endoplasmic reticulum stress with hepatocyte apoptosis in early alcoholic liver disease
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STING Specifies IRF3 Phosphorylation by TBK1 in the Cytosolic DNA Signaling Pathway
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SCIENCE SIGNALING (2012)
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CELL (2010)
The Ubiquitin Ligase RNF5 Regulates Antiviral Responses by Mediating Degradation of the Adaptor Protein MITA
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IMMUNITY (2009)