4.8 Article

Identification of necroptosis-related subtypes and prognosis model in triple negative breast cancer

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biotechnology & Applied Microbiology

A Novel Necroptosis-Related miRNA Signature for Predicting the Prognosis of Breast Cancer Metastasis

Lin Zheng et al.

Summary: This study identified a prognostic multi-miRNA molecular marker associated with necroptosis, with hsa-miR-331-3p showing strong correlation with patient prognosis. The model established from miRNA data was found to have predictive ability and targeted genes enriched in transcriptional initiation and cell membrane trafficking, shedding light on potential mechanisms for future research on necroptosis-related genes in breast cancer metastasis.

DISEASE MARKERS (2022)

Article Medical Laboratory Technology

Necroptosis-related lncRNA to establish novel prognostic signature and predict the immunotherapy response in breast cancer

Fangyue Chen et al.

Summary: This study investigates the immune landscape in breast cancer by screening necroptosis-related long non-coding RNAs (lncRNAs). The results show that these lncRNAs are related to immune-related pathways and that the risk score is significantly correlated with immune cell infiltration and ESTIMATE score. Furthermore, patients with higher risk scores show better immune checkpoint blockade response.

JOURNAL OF CLINICAL LABORATORY ANALYSIS (2022)

Article Oncology

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

Hyuna Sung et al.

Summary: The global cancer burden in 2020 saw an estimated 19.3 million new cancer cases and almost 10.0 million cancer deaths. Female breast cancer surpassed lung cancer as the most commonly diagnosed cancer, while lung cancer remained the leading cause of cancer death. These trends are expected to rise in 2040, with transitioning countries experiencing a larger increase compared to transitioned countries due to demographic changes and risk factors associated with globalization and a growing economy. Efforts to improve cancer prevention measures and provision of cancer care in transitioning countries will be crucial for global cancer control.

CA-A CANCER JOURNAL FOR CLINICIANS (2021)

Review Oncology

The Role of Breast Cancer Stem Cells in Chemoresistance and Metastasis in Triple-Negative Breast Cancer

Lin He et al.

Summary: Triple negative breast cancer lacks targeted therapies and has poor prognosis. Chemotherapy is the main treatment, but recent advances have shown the importance of breast cancer stem cells in tumor initiation, metastasis, and chemoresistance. Targeting breast cancer stem cells may lead to new therapies that can improve patient survival rates.

CANCERS (2021)

Article Oncology

Necroptosis-Related lncRNAs: Predicting Prognosis and the Distinction between the Cold and Hot Tumors in Gastric Cancer

Zirui Zhao et al.

Summary: This study constructed a model with necroptosis-related lncRNAs to predict prognosis and aid in precision medication for gastric cancer patients. Analysis of IC50 differences between risk groups and clustering helped effectively distinguish between cold and hot tumors, contributing to precise mediation.

JOURNAL OF ONCOLOGY (2021)

Article Immunology

Tumor Mutation Burden and Immune Invasion Characteristics in Triple Negative Breast Cancer: Genome High-Throughput Data Analysis

Chundi Gao et al.

Summary: In this study, it was found that TNBC patients in the high TMB group had a higher survival rate, with differences in immune cell infiltration between the two groups. The FAT3 gene plays an important role in TNBC, not only related to patient prognosis, but also affecting immune cell infiltration.

FRONTIERS IN IMMUNOLOGY (2021)

Review Dermatology

Role of necroptosis in infection-related, immune-mediated, and autoimmune skin diseases

Lulu Liu et al.

Summary: Regulated necrosis, or necroptosis, is a programmed cell death pathway that is distinct from apoptosis, involving factors like tumor necrosis factor and Toll-like receptors. Evidence suggests that necroptosis plays a role in both physiological regulation and the pathogenesis of diseases like septicemia and neurodegenerative diseases. Studies have shown that necroptosis is also implicated in various skin diseases, including infection-related, immune-mediated conditions, and malignant tumors.

JOURNAL OF DERMATOLOGY (2021)

Review Oncology

Molecular Mechanisms Associated with Brain Metastases in HER2-Positive and Triple Negative Breast Cancers

Sarah Bryan et al.

Summary: Breast cancer is the most common malignant tumor among women globally and becomes incurable once it spreads to the brain. Approximately 30% of metastatic breast cancer patients develop brain metastases, with HER2-positive and triple-negative molecular subtypes being associated with an increased risk. Genetic and molecular mechanisms linked to these subtypes influence brain metastasis formation, presenting potential therapeutic strategies to prevent or slow progression.

CANCERS (2021)

Article Oncology

TNFSF9 Is a Prognostic Biomarker and Correlated with Immune Infiltrates in Pancreatic Cancer

Jiao Wu et al.

Summary: The TNFSF9 gene has been found to have increased expression in pancreatic cancer, with high levels associated with poor overall and relapse-free survival. Additionally, high TNFSF9 expression correlates negatively with CD8(+) T cell infiltration and strongly with M1 macrophages in pancreatic cancer. These findings suggest that TNFSF9 may serve as a prognostic biomarker in pancreatic cancer, influencing immune cell infiltration phenotypes.

JOURNAL OF GASTROINTESTINAL CANCER (2021)

Review Oncology

Triple-negative breast cancer therapy: Current and future perspectives (Review)

Kwang-Ai Won et al.

INTERNATIONAL JOURNAL OF ONCOLOGY (2020)

Article Medicine, General & Internal

Multi-omics analysis of tumor mutational burden combined with prognostic assessment in epithelial ovarian cancer based on TCGA database

Jinhui Liu et al.

INTERNATIONAL JOURNAL OF MEDICAL SCIENCES (2020)

News Item Biotechnology & Applied Microbiology

Death by inflammation: drug makers chase the master controller

Cormac Sheridan

NATURE BIOTECHNOLOGY (2019)

Correction Biotechnology & Applied Microbiology

Death by inflammation: drug makers chase the master controller (vol 37, pg 111, 2019)

Cormac Sheridan

NATURE BIOTECHNOLOGY (2019)

Article Multidisciplinary Sciences

RIP1 kinase inhibitor halts the progression of an immune-induced demyelination disease at the stage of monocyte elevation

Sitao Zhang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Review Biochemistry & Molecular Biology

The role of necroptosis in cancer biology and therapy

Yitao Gong et al.

MOLECULAR CANCER (2019)

Article Medicine, Research & Experimental

Titin mutation associated with responsiveness to checkpoint blockades in solid tumors

Qingzhu Jia et al.

JCI INSIGHT (2019)

Article Medicine, General & Internal

Nivolumab plus Ipilimumab in Lung Cancer with a High Tumor Mutational Burden

M. D. Hellmann et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

Review Biochemistry & Molecular Biology

Targeting Breast Cancer Stem Cells to Overcome Treatment Resistance

Sonia Palomeras et al.

MOLECULES (2018)

Article Biochemistry & Molecular Biology

Resistance of primary breast cancer cells with enhanced pluripotency and stem cell activity to sex hormonal stimulation and suppression

Mostafa Nasr et al.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2018)

Article Multidisciplinary Sciences

RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS

Yasushi Ito et al.

SCIENCE (2016)

Article Multidisciplinary Sciences

The clonal and mutational evolution spectrum of primary triple-negative breast cancers

Sohrab P. Shah et al.

NATURE (2012)

Article Multidisciplinary Sciences

Comprehensive molecular portraits of human breast tumours

Daniel C. Koboldt et al.

NATURE (2012)

Review Biochemistry & Molecular Biology

Hallmarks of Cancer: The Next Generation

Douglas Hanahan et al.

Review Biochemistry & Molecular Biology

Immunity, Inflammation, and Cancer

Sergei I. Grivennikov et al.

Article Cell Biology

Necroptosis as an alternative form of programmed cell death

Dana E. Christofferson et al.

CURRENT OPINION IN CELL BIOLOGY (2010)

Review Oncology

Signaling Through OX40 Enhances Antitumor Immunity

Shawn M. Jensen et al.

SEMINARS IN ONCOLOGY (2010)

Article Biochemistry & Molecular Biology

Identification of RIP1 kinase as a specific cellular target of necrostatins

Alexei Degterev et al.

NATURE CHEMICAL BIOLOGY (2008)