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CANCERS (2019)
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
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Thomas Grewal et al.
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Dhirendra K. Simanshu et al.
CELL (2017)
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Youtao Liu et al.
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The novel RacE-binding protein GflB sharpens Ras activity at the leading edge of migrating cells
Hiroshi Senoo et al.
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A Model for Direction Sensing in Dictyostelium discoideum: Ras Activity and Symmetry Breaking Driven by a Gβγ-Mediated, Gα2-Ric8-Dependent Signal Transduction Network
Yougan Cheng et al.
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Anne Hennig et al.
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Marianne Strazza et al.
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EBP1 suppresses growth, migration, and invasion of thyroid cancer cells through upregulating RASAL expression
Hongyan Liu et al.
TUMOR BIOLOGY (2015)
Neurofibromin controls macropinocytosis and phagocytosis in Dictyostelium
Gareth Bloomfield et al.
ELIFE (2015)
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Senena Corbalan-Garcia et al.
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Oliver Hoeller et al.
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Akihiko Nakajima et al.
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Annette Mueller-Taubenberger et al.
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Two distinct functions for PI3-kinases in macropinocytosis
Oliver Hoeller et al.
JOURNAL OF CELL SCIENCE (2013)
Ras activation and symmetry breaking during Dictyostelium chemotaxis
Arjan Kortholt et al.
JOURNAL OF CELL SCIENCE (2013)
An excitable signal integrator couples to an idling cytoskeletal oscillator to drive cell migration
Chuan-Hsiang Huang et al.
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Andrew R. Houk et al.
CELL (2012)
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Wouter-Jan Rappel et al.
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Sabine Suire et al.
EMBO JOURNAL (2012)
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Kosuke Takeda et al.
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Yanfeng Dai et al.
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Pascale G. Charest et al.
DEVELOPMENTAL CELL (2010)
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Xuehua Xu et al.
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Wenzhe Ma et al.
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Taeck J. Jeon et al.
DEVELOPMENTAL BIOLOGY (2009)
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Arjan Kortholt et al.
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Sheng Zhang et al.
CURRENT BIOLOGY (2008)
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Parvin Bolourani et al.
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Taeck J. Jeon et al.
JOURNAL OF CELL BIOLOGY (2007)
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Rap1 controls cell adhesion and cell motility through the regulation of myosin II
Taeck J. Jeon et al.
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A chemoattractant-mediated Gi-coupled pathway activates adenylyl cyclase in human neutrophils
Dana C. Mahadeo et al.
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Molecular mechanisms involved in Ras inactivation: the annexin A6-p120GAP complex
Thomas Grewal et al.
BIOESSAYS (2006)
The GAP1 family of GTPase-activating proteins: spatial and temporal regulators of small GTPase signalling
S. Yarwood et al.
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Sabine Suire et al.
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Arjan Kortholt et al.
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To stabilize neutrophil polarity, PIP3 and Cdc42 augment RhoA activity at the back as well as signals at the front
Alexandra Van Keymeulen et al.
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Key role of local regulation in chemosensing revealed by a new molecular interaction-based modeling method
Martin Meier-Schellersheim et al.
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An essential function for the calcium-promoted Ras inactivator in Fcγ receptor-mediated phagocytosis
J Zhang et al.
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CAPRI and RASAL impose different modes of information processing on Ras due to contrasting temporal filtering of Ca2+
Q Liu et al.
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Quantitative imaging of single live cells reveals spatiotemporal dynamics of multistep signaling events of chemoattractant gradient sensing in Dictyostelium
XH Xu et al.
MOLECULAR BIOLOGY OF THE CELL (2005)
The Dictyostelium genome encodes numerous RasGEFs with multiple biological roles
A Wilkins et al.
GENOME BIOLOGY (2005)
Identification of a Ras GTPase-activating protein regulated by receptor-mediated Ca2+ oscillations
SA Walker et al.
EMBO JOURNAL (2004)
Chemotaxis: Signalling the way forward
PJM Van Haastert et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2004)
Chemotaxis: signalling modules join hands at front and tail
M Postma et al.
EMBO REPORTS (2004)
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AT Sasaki et al.
JOURNAL OF CELL BIOLOGY (2004)
Chemoattractant-induced Ras activation during Dictyostelium aggregation
H Kae et al.
EMBO REPORTS (2004)
Eukaryotic chemotaxis: Distinctions between directional sensing and polarization
P Devreotes et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Roles of Gβγ in membrane recruitment and activation of p110γ/p101 phosphoinositide 3-kinase γ
C Brock et al.
JOURNAL OF CELL BIOLOGY (2003)
Temporal and spatial regulation of chemotaxis
M Iijima et al.
DEVELOPMENTAL CELL (2002)
Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis
S Funamoto et al.
CELL (2002)
Tumor suppressor PTEN mediates sensing of chemoattractant gradients
M Iijima et al.
CELL (2002)
CAPRI regulates Ca2+-dependent inactivation of the Ras-MAPK pathway
PJ Lockyer et al.
CURRENT BIOLOGY (2001)
Receptor-mediated activation of heterotrimeric G-proteins in living cells
C Janetopoulos et al.
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Roles of PLC-β2 and -β3 and PI3Kγ in chemoattractant-mediated signal transduction
Z Li et al.
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