New endoscopic tools in inflammatory bowel disease

Endoscopic remission is now considered the ultimate long-term goal for treating inflammatory bowel disease (IBD). Recent advances in endoscopic techniques have progressively added new tools to the armamentarium of endoscopists for a deeper assessment and characterisation of the intestinal mucosa. Virtual Electronic chromoendoscopy is widely available in the endoscopic units, leading to a more accurate evaluation of the vascular and mucosal architecture of the colon, reducing the gap with histology, which is considered a favourable long-term measure. In addition, advanced, sophisticated techniques such as endocytoscope and confocal laser endomicroscopy provide insights into individualised and personalised IBD therapy. Finally, high expectations are placed on the advent of Artificial Intelligence (AI) with promising applications that have the potential to revolutionise IBD diagnosis and management. Here, we discuss state-of-the-art of endoscopic techniques and their applicability to accurate assess endoscopic and histological remission, predict response to therapy and detect, characterise and guide treatment of colonic dysplastic lesions. We are seeing the dawn of a new era wherein the applications of these new endoscopic tools, hand in hand with AI, offer the most incredible opportunity to deliver precision medicine to patients with IBD.

Automated summary

Endoscopic remission is considered the ultimate long-term goal for treating inflammatory bowel disease. Advances in endoscopic techniques, such as virtual electronic chromoendoscopy, endocytoscope, and confocal laser endomicroscopy, provide more accurate assessments of the intestinal mucosa. Artificial Intelligence (AI) shows promise in revolutionizing IBD diagnosis and management. These new endoscopic tools, combined with AI, offer incredible opportunities for precision medicine in patients with IBD.