4.7 Review

Gold-Nanoparticle Hybrid Nanostructures for Multimodal Cancer Therapy

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Pharmacology & Pharmacy

Factors affecting the dynamics and heterogeneity of the EPR effect: pathophysiological and pathoanatomic features, drug formulations and physicochemical factors

Rayhanul Islam et al.

Summary: The EPR effect is crucial for anticancer nanomedicine design, but its efficacy varies depending on factors such as vascular mediators, tumor blood flow, and physicochemical properties of nanomedicines. Restoring obstructed tumor blood flow and improving tumor vascular permeability are key strategies for overcoming barriers to the EPR effect.

EXPERT OPINION ON DRUG DELIVERY (2022)

Article Engineering, Biomedical

Fe3O4@Au core-shell hybrid nanocomposite for MRI-guided magnetic targeted photo-chemotherapy

Tahereh Khani et al.

Summary: In this study, researchers successfully constructed iron oxide-gold core-shell hybrid nanocomposites that can be detected through MRI and targeted towards tumors using an external magnetic field. The gold shell can respond to near-infrared light, generating localized heating for photothermal therapy. Experiments showed that this nanocomposite can effectively combine chemotherapy and photothermal therapy, resulting in superior therapeutic outcome.

LASERS IN MEDICAL SCIENCE (2022)

Article Multidisciplinary Sciences

Radiation dose enhancement using gold nanoparticles with a diamond linear accelerator target: a multiple cell type analysis

Olivia Piccolo et al.

Summary: Radiotherapy is an effective cancer treatment, but it can cause damage to healthy tissues. Using gold nanoparticles to enhance radiotherapy has been shown to be effective. A new study demonstrates that using a diamond target beam along with gold nanoparticles can increase the radiation dose and improve the killing effect on head and neck cancer cells.

SCIENTIFIC REPORTS (2022)

Article Polymer Science

Drug Delivery from Stimuli-Responsive Poly(N-isopropylacrylamide-co-N-isopropylmethacrylamide)/Chitosan Core/Shell Nanohydrogels

Andres Ortega-Garcia et al.

Summary: This paper reports the synthesis of stimulus-responsive polymer nanohydrogels with a core/shell structure using batch emulsion polymerization in the presence of chitosan micelles. The nanohydrogels were loaded with the drug doxycycline hyclate and showed a higher release amount at acidic pH. Mathematical models were used to fit the experimental drug release data.

POLYMERS (2022)

Article Engineering, Biomedical

Facile one-step synthesis of NIR-Responsive siRNA-Inorganic hybrid nanoplatform for imaging-guided photothermal and gene synergistic therapy

Xiuna Jia et al.

Summary: Diagnosis-guided synergistic treatment based on innovative nanomaterials is important for the development of anti-cancer therapies. This study developed a smart carrier named LPAR, which can selectively deliver and release genes using near-infrared light and convert the light into heat for photothermal synergistic therapy. LPAR also possesses the capability of triple-modal imaging.

BIOMATERIALS (2022)

Article Pharmacology & Pharmacy

pH-temperature dual-sensitive nucleolipid-containing stealth liposomes anchored with PEGylated AuNPs for triggering delivery of doxorubicin

Monica C. Garcia et al.

Summary: This study reports the development of pH/thermo-sensitive liposomes using nucleolipids and modified with gold nanoparticles. The results demonstrate that these liposomes can efficiently release anticancer drugs and exhibit significant toxicity against cancer cells.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2022)

Article Multidisciplinary Sciences

Multimodal bioimaging using nanodiamond and gold hybrid nanoparticles

Yu-Chung Lin et al.

Summary: Hybrid core-shell nanodiamond-gold nanoparticles with tunable and tailored properties have been synthesized, providing new options for optical labeling, imaging, sensing, drug delivery, and targeted treatment in biomedical applications. The combination of nanostructured gold and nanodiamond properties offers various bioimaging modalities and potential theranostic functionalities.

SCIENTIFIC REPORTS (2022)

Article Polymer Science

pH-Responsive Nanocarriers in Cancer Therapy

Nour M. AlSawaftah et al.

Summary: Stimuli-responsive nanoparticles have shown promising potential in overcoming the limitations of conventional chemotherapy. pH-sensitive nanoparticles, in particular, have proven to be highly efficient in delivering drugs to tumors compared to conventional nanoparticles. This review summarizes the different strategies used to develop pH-sensitive nanoparticles for cancer therapy.

POLYMERS (2022)

Article Materials Science, Biomaterials

A Three-Dimensional Printable Hydrogel Formulation for the Local Delivery of Therapeutic Nanoparticles to Cervical Cancer

Mariia Kiseleva et al.

Summary: This study demonstrates the potential of Pluronic F127-alginate hydrogel in the topical administration of NP-releasing gels applied to vaginal wall therapy. The hydrogel formulation has good mucoadhesive properties and nanoparticle release performance, and can be personalized through 3D printing.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2022)

Review Biotechnology & Applied Microbiology

Next-generation engineered nanogold for multimodal cancer therapy and imaging: a clinical perspectives

Madhusudhan Alle et al.

Summary: Cancer remains a significant threat to human life with current treatment options unable to prevent millions of deaths each year. Nanoparticles, particularly nanogold (AuNPs), offer a promising approach for effective cancer treatment through modulation of their size, shape, and attachment of targeting agents. This review focuses on recent advancements in functionalizing AuNPs-based nanoconstructs for cancer imaging and therapy using combinatorial multimodal approaches, including photothermal therapy, photodynamic therapy, chemotherapy, radiotherapy, and immunotherapy.

JOURNAL OF NANOBIOTECHNOLOGY (2022)

Review Chemistry, Multidisciplinary

Ultrasound Triggering of Liposomal Nanodrugs for Cancer Therapy: A Review

Wafa N. Bahutair et al.

Summary: Smart drug delivery systems utilizing nanoparticles as drug carriers have shown great potential in enhancing the targetability of anticancer agents and limiting their side effects. Liposomes, as one of the most investigated nanoplatforms, have the capability of encapsulating different types of drugs and good biocompatibility. Liposomal nanodrug systems can release drugs at targeted diseased sites, sparing normal cells from undesired cytotoxic effects. Ultrasound-triggered liposomal nanodrug systems have proven to be effective in spatially and temporally controlling and stimulating drug release in cancer therapy.

NANOMATERIALS (2022)

Review Nanoscience & Nanotechnology

Bioresponsive nanogels for protein delivery

Xiao Xu et al.

Summary: Protein drugs have high specificity and efficacy, but their poor stability, plasma degradation, inferior cell membrane permeability, and immunogenicity limit their in vivo application. Bioresponsive nanogels can increase the stability and decrease the immunogenicity of protein drugs, and programmatically release them at target sites with distinct biosignals, showing potential to improve therapeutic efficacy and reduce adverse effects.
Article Green & Sustainable Science & Technology

Shape effects of gold nanoparticles in photothermal cancer therapy

W. Yang et al.

Summary: Gold nanoparticles based Plasmonic Photothermal Therapy (PPTT) shows potential in cancer treatment by inducing local hyperthermia in cancer cells or tissues. Among three commonly studied gold nanostructures, gold nanostars (AuNSTs) demonstrate the highest photo-thermal conversion efficiency, making them the most promising agent for PTT therapy.

MATERIALS TODAY SUSTAINABILITY (2021)

Article Materials Science, Biomaterials

Gold liposomes for brain-targeted drug delivery: Formulation and brain distribution kinetics

Roshan Sonkar et al.

Summary: This study successfully formulated transferrin receptor targeted gold-based liposomes containing docetaxel and glutathione reduced gold nanoparticles for brain-targeted drug delivery; the sustained drug release and in-vivo results demonstrated that targeted gold liposomes can deliver docetaxel to the brain more effectively than marketed products.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2021)

Article Nanoscience & Nanotechnology

In Situ Nanotransformable Hydrogel for Chemo-Photothermal Therapy of Localized Tumors and Targeted Therapy of Highly Metastatic Tumors

Syed Baseeruddin Alvi et al.

Summary: The study developed a smart nanotransforming hydrogel that transformed in situ into polymeric nanoparticles capable of targeting primary and secondary metastatic tumors. The nanoparticles exhibited pH-responsive drug release and demonstrated efficient inhibition of lung metastases in vivo, compared to chemotherapy.

ACS APPLIED MATERIALS & INTERFACES (2021)

Article Engineering, Biomedical

NIR irradiation-controlled drug release utilizing injectable hydrogels containing gold-labeled liposomes for the treatment of melanoma cancer

Ji Eun Won et al.

Summary: A new injectable hydrogel system for sustained drug release at the tumor site has been developed in this study. The combined therapeutic efficacy of the hydrogel system and a nanoparticle-based immunotherapeutic vaccine for melanoma cancer was demonstrated, showing a potential combination approach for chemo- and immunotherapies for cancer treatment.

ACTA BIOMATERIALIA (2021)

Article Chemistry, Applied

A novel bioreducible and pH-responsive magnetic nanohydrogel based on β-cyclodextrin for chemo/hyperthermia therapy of cancer

Khadijeh Soleimani et al.

Summary: A new strategy for designing and developing a magnetic smart drug delivery system based on beta-cyclodextrin and poly(2-ethyl-2-oxazoline) was reported. The developed system showed high drug loading value, slow and stimuli-triggered drug release behavior, and acceptable magnetic properties, making it a potential efficient and smart drug delivery system for cancer therapy and diagnosis.

CARBOHYDRATE POLYMERS (2021)

Article Medicine, Research & Experimental

Composite phospholipid-gold nanoparticles with targeted fragment for tumor imaging

M. A. Sanzhakov et al.

Summary: The study focused on constructing composite phospholipid-gold nanoparticles using soy phosphatidylcholine and a targeted ligand to enhance specific delivery into tumor cells and visualization of malignant neoplasms. In vitro and in vivo experiments demonstrated a significant increase in accumulation of the nanoparticles with a targeted fragment, showing promising potential for early diagnosis and treatment of various types of tumors.

BIOMEDICINE & PHARMACOTHERAPY (2021)

Article Chemistry, Physical

Gold nanoparticle-coated thermosensitive liposomes for the triggered release of doxorubicin, and photothermal therapy using a near-infrared laser

Kento Koga et al.

Summary: The study developed gold nanoparticle-coated liposome/doxorubicin for controlled drug release and photothermal effect, showing synergistic therapeutic efficacy on lung cancer cells compared to monotherapy. This approach holds promise for cancer treatment with the use of near-infrared laser irradiation.

COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS (2021)

Review Biochemistry & Molecular Biology

Safe Nanoparticles: Are We There Yet?

Wided Najahi-Missaoui et al.

Summary: The field of nanotechnology has rapidly grown over the past two decades, leading to the emergence of nanoparticles as promising tools in various applications. However, questions about the toxicity and safety of nanoparticles remain unanswered, despite efforts to understand them. Several approaches to minimize and prevent nanoparticle toxicity have been identified through research.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Article Chemistry, Multidisciplinary

Stimuli-Responsive, Plasmonic Nanogel for Dual Delivery of Curcumin and Photothermal Therapy for Cancer Treatment

Fadak Howaili et al.

Summary: In this study, a dual-responsive nanogel system with the incorporation of gold nanoparticles for drug delivery and photothermal therapy was synthesized. Characterization of the nanogel and evaluation of its cytocompatibility were conducted, showing promising potential for cancer therapy.

FRONTIERS IN CHEMISTRY (2021)

Article Polymer Science

Fluorescence Modulation of Conjugated Polymer Nanoparticles Embedded in Poly(N-Isopropylacrylamide) Hydrogel

Ho Namgung et al.

Summary: A series of conjugated polymers emitting red, green, and blue fluorescence were synthesized via the Suzuki coupling polymerization and fabricated into a thermoresponsive polymer hydrogel, which could provide thermally reversible fluorescence changes with potential applications.

POLYMERS (2021)

Article Biotechnology & Applied Microbiology

Petal-like size-tunable gold wrapped immunoliposome to enhance tumor deep penetration for multimodal guided two-step strategy

Yanan Li et al.

Summary: The HER2-modified thermosensitive liposome designed in this study effectively releases anti-tumor drugs, accelerates the renal metabolism of gold clusters through degradation of the gold nanoclusters, and exhibits good photothermal conversion ability and tumor targeting. Furthermore, this carrier can be used for multimodal imaging and combination therapy.

JOURNAL OF NANOBIOTECHNOLOGY (2021)

Article Oncology

Cancer statistics for the year 2020: An overview

Jacques Ferlay et al.

Summary: The study briefly reviews the methods and data sources used in compiling the IARC GLOBOCAN cancer statistics for 2020 and summarizes the main results. It estimated that there were nearly 19.3 million new cancer cases and almost 10 million cancer deaths worldwide in 2020, with the most commonly diagnosed cancers being female breast cancer and lung cancer, and the most common causes of cancer death being lung cancer and liver cancer.

INTERNATIONAL JOURNAL OF CANCER (2021)

Review Chemistry, Multidisciplinary

Polymeric micelles in drug delivery: An insight of the techniques for their characterization and assessment in biorelevant conditions

M. Ghezzi et al.

Summary: Polymeric micelles, innovative aggregation colloids formed by self-assembling of amphiphilic polymers in solution, offer advantages in drug administration but also face challenges such as lower stability and complex characterization. Understanding their interaction with the biological environment is crucial, and a combination of different characterization techniques can provide a deeper insight into their in vivo behavior.

JOURNAL OF CONTROLLED RELEASE (2021)

Review Oncology

Recent Development of Gold Nanoparticles as Contrast Agents for Cancer Diagnosis

Dong Luo et al.

Summary: The development of nanotechnology has revolutionized the diagnosis and therapy of diseases, with gold nanoparticles being extensively researched for their excellent performance in this field. Gold nanoparticles have multiple functions and high efficiency, making them ideal for both therapeutic delivery and imaging diagnostics in cancer therapies and other biomedical applications.

CANCERS (2021)

Article Chemistry, Multidisciplinary

Near-infrared light-responsive liposomes for protein delivery: Towards bleeding-free photothermally-assisted thrombolysis

Ahmed Refaat et al.

Summary: Smart drug delivery systems utilizing near-infrared light-responsive liposomal gold nanorods show potential for targeted therapy of cancer and cardiovascular diseases with minimal adverse effects. This novel platform combines light-triggered protein release with photothermal thrombolytic effects for site-specific thrombolysis, offering a promising approach for advanced medical treatment.

JOURNAL OF CONTROLLED RELEASE (2021)

Review Biochemistry & Molecular Biology

Functionalization of Metal and Carbon Nanoparticles with Potential in Cancer Theranostics

Nicolo Mauro et al.

Summary: Cancer theranostics is a novel medical concept that aims to integrate diagnosis, monitoring, and therapy on a unique nanoplatform in a non-invasive manner to eliminate solid tumors. Surface functionalization of nanoplatforms is a useful protocol for tuning their structures and properties, making it more reliable and amenable to adjustments for specific applications.

MOLECULES (2021)

Article Biotechnology & Applied Microbiology

Development of theranostic dual-layered Au-liposome for effective tumor targeting and photothermal therapy

Miyeon Jeon et al.

Summary: The novel dual-layered nanomaterial LAL, with the addition of a liposomal layer and PEG functionalization, shows improved in vivo stability and tumor-targeting ability. Cu-64-LAL demonstrates good blood circulation and tumor targeting capabilities in PET imaging.

JOURNAL OF NANOBIOTECHNOLOGY (2021)

Review Chemistry, Multidisciplinary

Recent Advances in Hollow Gold Nanostructures for Biomedical Applications

Jeong-Min Park et al.

Summary: Hollow gold nanostructures have significant advantages such as absorbing near-infrared light, anti-corrosiveness, and large surface area, making them suitable for biomedical applications. They can be used for drug delivery, biosensing, bioimaging, and photothermal therapy.

FRONTIERS IN CHEMISTRY (2021)

Review Nanoscience & Nanotechnology

Multifunctional Gold Nanoparticles for Improved Diagnostic and Therapeutic Applications: A Review

Nicole Remaliah Samantha Sibuyi et al.

Summary: The medical properties of metals have been explored for centuries and metal nanoparticles like AuNPs have shown great potential in various medical applications. They have unique properties compared to their bulk counterparts and are used in drug delivery, photothermal therapy, contrast agents, therapeutic agents, radiosensitizers, and gene transfection agents in medicine. AuNP-based systems have shown promise in improving efficacy in disease diagnosis and therapy, and strategies to improve their biocompatibility are being explored.

NANOSCALE RESEARCH LETTERS (2021)

Review Medicine, General & Internal

New approaches and procedures for cancer treatment: Current perspectives

Dejene Tolossa Debela et al.

Summary: Cancer is a global health problem causing one in six deaths worldwide. Recent advances in cancer therapy, such as stem cell therapy, targeted therapy, ablation therapy, and nanoparticles, show promising efficacy in treating cancer with less harm to healthy cells. Ongoing research is focused on developing safe and efficient cancer nanomedicines.

SAGE OPEN MEDICINE (2021)

Article Public, Environmental & Occupational Health

The incurable metastatic breast cancer experience through metaphors: the fight and the unveiling

Alexandra Guite-Verret et al.

Summary: This study analyzed the metaphors used by four women with incurable metastatic breast cancer in their personal blogs to gain a better understanding of their experiences. The results show that the war and unveiling metaphors played significant roles in the women's experiences, highlighting the difficulties of fighting cancer and the eventual collapse in battle, as well as the development of a renewed perspective on life. The bloggers' efforts to lift the veil on the complex experience emphasize the importance of women with metastatic breast cancer being able to share their experiences in a supportive context.

INTERNATIONAL JOURNAL OF QUALITATIVE STUDIES ON HEALTH AND WELL-BEING (2021)

Article Biotechnology & Applied Microbiology

Triggered drug release from hybrid thermoresponsive nanoparticles using near infrared light

Isabel Ortiz de Solorzano et al.

NANOMEDICINE (2020)

Article Chemistry, Multidisciplinary

A Neutrophil-Inspired Supramolecular Nanogel for Magnetocaloric-Enzymatic Tandem Therapy

Qi Zhang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

Article Pharmacology & Pharmacy

Gold nanoparticles promote a multimodal synergistic cancer therapy strategy by co-delivery of thermo-chemo-radio therapy

Zahra Alamzadeh et al.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2020)

Review Biochemistry & Molecular Biology

Mechanisms of Multidrug Resistance in Cancer Chemotherapy

Karol Bukowski et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Article Nanoscience & Nanotechnology

Brain Targeted Gold Liposomes Improve RNAi Delivery for Glioblastoma

Nilmary Grafals-Ruiz et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2020)

Article Instruments & Instrumentation

Challenges in nanomedicine clinical translation

Josbert M. Metselaar et al.

DRUG DELIVERY AND TRANSLATIONAL RESEARCH (2020)

Review Pharmacology & Pharmacy

Hyperthermia can alter tumor physiology and improve chemo- and radio-therapy efficacy

Michael Dunne et al.

ADVANCED DRUG DELIVERY REVIEWS (2020)

Review Biotechnology & Applied Microbiology

Multifunctional Gold Nanoparticles: A Novel Nanomaterial for Various Medical Applications and Biological Activities

Xiaopei Hu et al.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2020)

Article Chemistry, Multidisciplinary

Smart gold nanocages for mild heat -triggered drug release and breaking chemoresistance

Huamei He et al.

JOURNAL OF CONTROLLED RELEASE (2020)

Article Biochemistry & Molecular Biology

Triple combination of heat, drug and radiation using alginate hydrogel co-loaded with gold nanoparticles and cisplatin for locally synergistic cancer therapy

Mehri Mirrahimi et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

Article Biotechnology & Applied Microbiology

Dual-responsive doxorubicin-loaded nanomicelles for enhanced cancer therapy

Xinyi Zhang et al.

JOURNAL OF NANOBIOTECHNOLOGY (2020)

Review Materials Science, Multidisciplinary

Polymer-Based Nanomaterials for Noninvasive Cancer Photothermal Therapy

Chanchan Yu et al.

ACS APPLIED POLYMER MATERIALS (2020)

Review Materials Science, Biomaterials

The regulation of nanomaterials and nanomedicines for clinical application: current and future perspectives

Rachel Foulkes et al.

BIOMATERIALS SCIENCE (2020)

Review Medicine, Research & Experimental

Ultrasmall gold nanoparticles in cancer diagnosis and therapy

Miao Fan et al.

THERANOSTICS (2020)

Review Multidisciplinary Sciences

Smart nanocarrier-based drug delivery systems for cancer therapy and toxicity studies: A review

Sarwar Hossen et al.

JOURNAL OF ADVANCED RESEARCH (2019)

Article Engineering, Biomedical

Enhancement of chemoradiation by co-incorporation of gold nanoparticles and cisplatin into alginate hydrogel

Mehri Mirrahimi et al.

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS (2019)

Article Biochemistry & Molecular Biology

Ultrastructural and optical characteristics of cancer cells treated by a nanotechnology based chemo-photothermal therapy method

Zahra Alamzadeh et al.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY (2019)

Review Biochemistry & Molecular Biology

Hydrogels and Their Applications in Targeted Drug Delivery

Radhika Narayanaswamy et al.

MOLECULES (2019)

Review Engineering, Biomedical

Stimulus-responsive polymeric nanogels as smart drug delivery systems

Sakineh Hajebi et al.

ACTA BIOMATERIALIA (2019)

Review Chemistry, Multidisciplinary

Gold Nanoparticles for Photothermal Cancer Therapy

Jeremy B. Vines et al.

FRONTIERS IN CHEMISTRY (2019)

Review Chemistry, Multidisciplinary

Crossing biological barriers with nanogels to improve drug delivery performance

Julio Cesar Cuggino et al.

JOURNAL OF CONTROLLED RELEASE (2019)

Article Biotechnology & Applied Microbiology

Hollow gold nanoshells-incorporated injectable genetically engineered hydrogel for sustained chemo-photothermal therapy of tumor

RuiMei Jin et al.

JOURNAL OF NANOBIOTECHNOLOGY (2019)

Review Chemistry, Multidisciplinary

Gold Nanoparticles and Nanorods in Nuclear Medicine: A Mini Review

Daria Maccora et al.

APPLIED SCIENCES-BASEL (2019)

Review Pharmacology & Pharmacy

Thermoresponsive polymer nanocarriers for biomedical applications

Alexandre Bordat et al.

ADVANCED DRUG DELIVERY REVIEWS (2019)

Article Pharmacology & Pharmacy

Recalcitrant Issues and New Frontiers in Nano-Pharmacology

Vinay Bhardwaj et al.

FRONTIERS IN PHARMACOLOGY (2019)

Review Chemistry, Physical

Recent progress of polymeric nanogels for gene delivery

Rima Kandil et al.

CURRENT OPINION IN COLLOID & INTERFACE SCIENCE (2019)

Article Chemistry, Multidisciplinary

Redox/pH dual-stimuli responsive camptothecin prodrug nanogels for on-demand drug delivery

Ying Qu et al.

JOURNAL OF CONTROLLED RELEASE (2019)

Review Medicine, Research & Experimental

Gold Nanoparticles in Cancer Treatment

Krzysztof Sztandera et al.

MOLECULAR PHARMACEUTICS (2019)

Article Nanoscience & Nanotechnology

Gold-nanobranched-shell based drug vehicles with ultrahigh photothermal efficiency for chemo-photothermal therapy

Yanping Liu et al.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2019)

Review Cardiac & Cardiovascular Systems

Effect on Platelet Function of Metal-Based Nanoparticles Developed for Medical Applications

Nadhim Kamil Hante et al.

FRONTIERS IN CARDIOVASCULAR MEDICINE (2019)

Article Biochemistry & Molecular Biology

NIR triggered liposome gold nanoparticles entrapping curcumin as in situ adjuvant for photothermal treatment of skin cancer

Surya Prakash Singh et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2018)

Review Nanoscience & Nanotechnology

Stimuli-responsive polymeric micelles for drug delivery and cancer therapy

Qing Zhou et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2018)

Article Engineering, Biomedical

Alginate hydrogel co-loaded with cisplatin and gold nanoparticles for computed tomography image-guided chemotherapy

Marzieh Keshavarz et al.

JOURNAL OF BIOMATERIALS APPLICATIONS (2018)

Article Materials Science, Biomaterials

A novel multi stimuli-responsive PEGylated hybrid gold/nanogels for co-delivery of doxorubicin and 6-mercaptopurine

Marjan Ghorbani et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2018)

Article Biochemistry & Molecular Biology

Dendrimers for Drug Delivery

Abhay Singh Chauhan

MOLECULES (2018)

Review Biochemistry & Molecular Biology

Liposomal Drug Delivery Systems and Anticancer Drugs

Temidayo O. B. Olusanya et al.

MOLECULES (2018)

Article Multidisciplinary Sciences

Controlled gene and drug release from a liposomal delivery platform triggered by X-ray radiation

Wei Deng et al.

NATURE COMMUNICATIONS (2018)

Review Nanoscience & Nanotechnology

Epitaxial growth of hybrid nanostructures

Chaoliang Tan et al.

NATURE REVIEWS MATERIALS (2018)

Article Multidisciplinary Sciences

Large T1 contrast enhancement using superparamagnetic nanoparticles in ultra-low field MRI

Xiaolu Yin et al.

SCIENTIFIC REPORTS (2018)

Article Nanoscience & Nanotechnology

Magnetic DNA Nanogels for Targeting Delivery and Multistimuli-Triggered Release of Anticancer Drugs

Chi Yao et al.

ACS APPLIED BIO MATERIALS (2018)

Article Biochemical Research Methods

Disintegrable NIR Light Triggered Gold Nanorods Supported Liposomal Nanohybrids for Cancer Theranostics

Deepak S. Chauhan et al.

BIOCONJUGATE CHEMISTRY (2018)

Review Oncology

Cure in metastatic breast cancer

Theresa Westphal et al.

MEMO-MAGAZINE OF EUROPEAN MEDICAL ONCOLOGY (2018)

Review Medicine, Research & Experimental

Factors associated with clinical trials that fail and opportunities for improving the likelihood of success: A review

David B. Fogel

CONTEMPORARY CLINICAL TRIALS COMMUNICATIONS (2018)

Review Physiology

Polymeric Nanogels as Drug Delivery Systems

J. Kousalova et al.

PHYSIOLOGICAL RESEARCH (2018)

Article Radiology, Nuclear Medicine & Medical Imaging

Preparation of liposomes encapsulated Epirubicin-gold nanoparticles for Tumor specific delivery and release

Selvaraj Kunjiappan et al.

BIOMEDICAL PHYSICS & ENGINEERING EXPRESS (2018)

Review Biochemistry & Molecular Biology

Magnetic stimuli-responsive chitosan-based drug delivery biocomposite for multiple triggered release

Michael Harris et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2017)

Editorial Material Biochemistry & Molecular Biology

Tumor Microenvironment and Metabolism

Li V. Yang

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)

Article Nanoscience & Nanotechnology

Multifunctional gold nanorods and docetaxel-encapsulated liposomes for combined thermo- and chemotherapy

Haiying Hua et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2017)

Article Pharmacology & Pharmacy

Bubble-generating nano-lipid carriers for ultrasound/CT imaging-guided efficient tumor therapy

Nan Zhang et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2017)

Review Biochemistry & Molecular Biology

Unique Roles of Gold Nanoparticles in Drug Delivery, Targeting and Imaging Applications

Fen-Ying Kong et al.

MOLECULES (2017)

Article Nanoscience & Nanotechnology

Gold nanoshell-based betulinic acid liposomes for synergistic chemo-photothermal therapy

Yanping Liu et al.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2017)

Article Chemistry, Multidisciplinary

One-Step in Situ Synthesis of Polypeptide-Gold Nanoparticles Hybrid Nanogels and Their Application in Targeted Photoacoustic Imaging

Rui-Mei Jin et al.

ACS SUSTAINABLE CHEMISTRY & ENGINEERING (2017)

Review Pharmacology & Pharmacy

Impact of Dendrimers on Solubility of Hydrophobic Drug Molecules

Sonam Choudhary et al.

FRONTIERS IN PHARMACOLOGY (2017)

Review Chemistry, Multidisciplinary

Magnetic targeting with superparamagnetic iron oxide nanoparticles for in vivo glioma

Marina Fontes de Paula Aguiar et al.

NANOTECHNOLOGY REVIEWS (2017)

Article Biochemistry & Molecular Biology

Gold nanorod embedded reduction responsive block copolymer micelle-triggered drug delivery combined with photothermal ablation for targeted cancer therapy

Sheetal Parida et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2017)

Review Chemistry, Multidisciplinary

The in vitro and in vivo toxicity of gold nanoparticles

Yan-Peng Jia et al.

CHINESE CHEMICAL LETTERS (2017)

Article Engineering, Biomedical

Nanoparticle-Hydrogel: A Hybrid Biomaterial System for Localized Drug Delivery

Weiwei Gao et al.

ANNALS OF BIOMEDICAL ENGINEERING (2016)

Review Chemistry, Multidisciplinary

Nanotechnology in hyperthermia cancer therapy: From fundamental principles to advanced applications

Jaber Beik et al.

JOURNAL OF CONTROLLED RELEASE (2016)

Review Oncology

Patient-derived xenografts: a relevant preclinical model for drug development

Luca Pompili et al.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2016)

Editorial Material Polymer Science

Stimuli-Responsive Polymers: Design, Synthesis, Characterization, and Applications

Dong Wang et al.

INTERNATIONAL JOURNAL OF POLYMER SCIENCE (2016)

Review Materials Science, Biomaterials

Stimuli-responsive dendrimers in drug delivery

Hui Wang et al.

BIOMATERIALS SCIENCE (2016)

Article Nanoscience & Nanotechnology

Lipid-coated gold nanocomposites for enhanced cancer therapy

Ji Hee Kang et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2015)

Article Nanoscience & Nanotechnology

One-Step Green Synthesis of Gold Nanoparticles Using Black Cardamom and Effect of pH on Its Synthesis

Ashwani Kumar Singh et al.

NANOSCALE RESEARCH LETTERS (2015)

Article Multidisciplinary Sciences

Amplification of oxidative stress by a dual stimuli-responsive hybrid drug enhances cancer cell death

Joungyoun Noh et al.

NATURE COMMUNICATIONS (2015)

Article Engineering, Biomedical

Mild Hyperthermia Enhances Transport of Liposomal Gemcitabine and Improves In Vivo Therapeutic Response

Dickson K. Kirui et al.

ADVANCED HEALTHCARE MATERIALS (2015)

Article Materials Science, Biomaterials

Light-responsible DNA hydrogel-gold nanoparticle assembly for synergistic cancer therapy

Jaejung Song et al.

JOURNAL OF MATERIALS CHEMISTRY B (2015)

Article Nanoscience & Nanotechnology

One-Step Green Synthesis of Gold Nanoparticles Using Black Cardamom and Effect of pH on Its Synthesis

Ashwani Kumar Singh et al.

NANOSCALE RESEARCH LETTERS (2015)

Review Pharmacology & Pharmacy

Advances and Challenges of Liposome Assisted Drug Delivery

Lisa Sercombe et al.

FRONTIERS IN PHARMACOLOGY (2015)

Review Polymer Science

Magnetic Gel Composites for Hyperthermia Cancer Therapy

Marleen Haering et al.

Article Nanoscience & Nanotechnology

Gold Nanorod Enhanced Two-Photon Excitation Fluorescence of Photosensitizers for Two-Photon Imaging and Photodynamic Therapy

Tingting Zhao et al.

ACS APPLIED MATERIALS & INTERFACES (2014)

Review Chemistry, Multidisciplinary

Perturbation of physiological systems by nanoparticles

Yi Zhang et al.

CHEMICAL SOCIETY REVIEWS (2014)

Review Nanoscience & Nanotechnology

Thermosensitive liposomal drug delivery systems: state of the art review

Barbara Kneidl et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2014)

Article Medicine, Research & Experimental

Gold Nanocage-Photosensitizer Conjugates for Dual-Modal Image-Guided Enhanced Photodynamic Therapy

Avinash Srivatsan et al.

THERANOSTICS (2014)

Review Pharmacology & Pharmacy

Multifunctional polymeric micelles for delivery of drugs and siRNA

Aditi M. Jhaveri et al.

FRONTIERS IN PHARMACOLOGY (2014)

Article Oncology

Magnetic nanoparticle hyperthermia enhancement of cisplatin chemotherapy cancer treatment

Alicia A. Petryk et al.

INTERNATIONAL JOURNAL OF HYPERTHERMIA (2013)

Review Pharmacology & Pharmacy

Polymer nanogels: A versatile nanoscopic drug delivery platform

Reuben T. Chacko et al.

ADVANCED DRUG DELIVERY REVIEWS (2012)

Review Pharmacology & Pharmacy

Thermosensitive sol-gel reversible hydrogels

Byeongmoon Jeong et al.

ADVANCED DRUG DELIVERY REVIEWS (2012)

Editorial Material Multidisciplinary Sciences

Raise standards for preclinical cancer research

C. Glenn Begley et al.

NATURE (2012)

Review Polymer Science

Alginate: Properties and biomedical applications

Kuen Yong Lee et al.

PROGRESS IN POLYMER SCIENCE (2012)

Article Chemistry, Physical

Polyrotaxane/gold nanoparticle hybrid nanomaterials as anticancer drug delivery systems

Mohsen Adeli et al.

JOURNAL OF MATERIALS CHEMISTRY (2011)

Review Chemistry, Multidisciplinary

Functionalized Gold Nanoparticles and Their Biomedical Applications

Pooja M. Tiwari et al.

NANOMATERIALS (2011)

Article Engineering, Biomedical

Gold nanoparticles enhance the radiation therapy of a murine squamous cell carcinoma

James F. Hainfeld et al.

PHYSICS IN MEDICINE AND BIOLOGY (2010)

Review Multidisciplinary Sciences

Gold nanoparticles: Optical properties and implementations in cancer diagnosis and photothermal therapy

Xiaohua Huang et al.

JOURNAL OF ADVANCED RESEARCH (2010)

Article Chemistry, Multidisciplinary

Multifunctional Nanoparticles for Combined Doxorubicin and Photothermal Treatments

Huiyul Park et al.

ACS NANO (2009)

Article Chemistry, Physical

Gold nanocages covered by smart polymers for controlled release with near-infrared light

Mustafa S. Yavuz et al.

NATURE MATERIALS (2009)

Article Chemistry, Multidisciplinary

Targeted Gold Nanoparticles Enable Molecular CT Imaging of Cancer

Rachela Popovtzer et al.

NANO LETTERS (2008)

Review Polymer Science

Hydrogels in drug delivery: Progress and challenges

Todd R. Hoare et al.

POLYMER (2008)

Review Polymer Science

Revie - Hydrogels as smart biomaterials

Jindrich Kopecek et al.

POLYMER INTERNATIONAL (2007)

Article Chemistry, Multidisciplinary

Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells

BD Chithrani et al.

NANO LETTERS (2006)