期刊
NANOMATERIALS
卷 12, 期 21, 页码 -出版社
MDPI
DOI: 10.3390/nano12213842
关键词
nanogaps; adhesion lithography; nanospheres lithography; surface-enhanced Raman spectroscopy; glucose; sensors
类别
资金
- NTNU [81771118]
- Norwegian Micro and Nano-Fabrication Facility, Norfab [245963/F50]
- Research Council of Norway [221860/F60]
This patterning method based on nanosphere lithography and adhesion lithography enables large-scale fabrication of 10 nm annular gap arrays on large areas with excellent reproducibility and high SERS performance. The technique also showcases an effective wearable SERS contact lens for glucose detection.
Applicable surface-enhanced Raman scattering (SERS) active substrates typically require low-cost patterning methodology, high reproducibility, and a high enhancement factor (EF) over a large area. However, the lack of reproducible, reliable fabrication for large area SERS substrates in a low-cost manner remains a challenge. Here, a patterning method based on nanosphere lithography and adhesion lithography is reported that allows massively parallel fabrication of 10-nm annular gap arrays on large areas. The arrays exhibit excellent reproducibility and high SERS performance, with an EF of up to 10(7). An effective wearable SERS contact lens for glucose detection is further demonstrated. The technique described here extends the range of SERS-active substrates that can be fabricated over large areas, and holds exciting potential for SERS-based chemical and biomedical detection.
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