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Risk Factors for Thoracic Aortic Dissection

GENES (2022)

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Article Cardiac & Cardiovascular Systems

Ciprofloxacin accelerates aortic enlargement and promotes dissection and rupture in Marfan mice

Scott A. LeMaire et al.

Summary: The study found that ciprofloxacin accelerates aortic root enlargement and increases the incidence of aortic dissection and rupture in Marfan mice. This effect is partially due to the suppression of lysyl oxidase expression, further compromising the inherited defect in aortic elastic fibers.

JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY (2022)

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Article Cardiac & Cardiovascular Systems

Combined Cardiovascular Syphilis and Type A Acute Aortic Dissection

William C. Roberts et al.

Summary: The occurrence of acute aortic dissection combined with cardiovascular syphilis is extremely rare, but a recently observed case presented with both conditions. Through operative repair, the entire ascending aorta was examined, revealing classic features of both diseases.

AMERICAN JOURNAL OF CARDIOLOGY (2022)

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Article Cardiac & Cardiovascular Systems

Type A aortic dissection is more aggressive in women

Simone Gasser et al.

Summary: The study found that female patients with acute aortic dissection type A were older and had a more aggressive and complicated preoperative course. They also had impaired neurological outcomes and lower survival rates.

EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY (2022)

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Article Surgery

Sex-Based Outcomes in Surgical Repair of Acute Type A Aortic Dissection:A Meta-Analysis and Meta-Regression

Kyle W. Lawrence et al.

JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY (2022)

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Article Multidisciplinary Sciences

Sex-related differences on the risks of in-hospital and late outcomes after acute aortic dissection: A nationwide population-based cohort study

Fang-Ting Chen et al.

Summary: This study evaluated the sex-related differences in perioperative and late outcomes for adult acute aortic dissection patients. The results showed no significant sex-related difference in in-hospital mortality or accumulative all-cause mortality. However, there were more redo aortic surgeries for males, and more postoperative depression for females.

PLOS ONE (2022)

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Review Cardiac & Cardiovascular Systems

Male-female differences in acute thoracic aortic dissection: a systematic review and meta-analysis

Frederike Meccanici et al.

Summary: This systematic review aimed to examine male-female differences in presentation, management, and outcomes in patients diagnosed with acute thoracic aortic dissection. While differences in patient and treatment characteristics were found, there were comparable early and overall mortality rates, and inconsistent outcome reporting. Further large prospective studies with standardized reporting are needed to improve understanding of these differences and guide individualized care.

INTERACTIVE CARDIOVASCULAR AND THORACIC SURGERY (2022)

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Review Medicine, General & Internal

Unraveling Bicuspid Aortic Valve Enigmas by Multimodality Imaging: Clinical Implications

Arturo Evangelista Masip et al.

Summary: Multimodality imaging is crucial for the diagnosis, follow-up, and surgical management of patients with bicuspid aortic valve (BAV). Transthoracic echocardiography is the first line imaging for BAV diagnosis, while computed tomography and magnetic resonance can improve the accuracy of aorta size measurement and evaluate aortic functional properties and blood flow patterns.

JOURNAL OF CLINICAL MEDICINE (2022)

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Article Cardiac & Cardiovascular Systems

Sex-Based Aortic Dissection Outcomes From the International Registry of Acute Aortic Dissection

Lauren Huckaby et al.

Summary: In-hospital mortality remains higher among women with TAAD but shows improvement in the last decade. Significant differences in presentation were noted in women, including older age and greater evidence of malperfusion. Although no distinctions in 5-year mortality or reintervention were observed, a tailored surgical approach should be considered to reduce sex disparities in early mortality rates for TAAD.

ANNALS OF THORACIC SURGERY (2022)

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Review Emergency Medicine

Misdiagnosis of aortic dissection: A systematic review of the literature

Saul Lovatt et al.

Summary: This article reviews the main reasons for misdiagnosis of aortic dissection. The study found that the misdiagnosis rate of aortic dissection reached 33.8%. Chest pain, back pain, and syncope are common symptoms of aortic dissection. Factors such as pre-existing hypertension, smoking, and coronary artery disease are associated with misdiagnosis. Improving the collection of medical history and using imaging can improve the accuracy of diagnosing aortic dissection.

AMERICAN JOURNAL OF EMERGENCY MEDICINE (2022)

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Article Emergency Medicine

Characteristics, clinical findings and outcomes of acute aortic dissection: A comparison between an Australian emergency department and the International Registry of Acute Aortic Dissection

John Slaven et al.

Summary: This study compared the characteristics and outcomes of patients diagnosed with Acute Aortic Dissection (AAD) at Liverpool Hospital in Australia (LPOOL) with those in the International Registry of Acute Aortic Dissection (IRAD), finding similar clinical features and outcomes. Individual studies identified syncope, weakness or paralysis, elevated lactate, and abnormal chest X-rays as independent predictors of 30-day mortality, while the time from the emergency department to the intensive care unit explained 28% of the variance in survival at 30 days.

EMERGENCY MEDICINE AUSTRALASIA (2022)

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Article Cardiac & Cardiovascular Systems

Impact of ethnicity and race on outcomes after thoracic endovascular aortic repair

Carlos E. Diaz-Castrillon et al.

Summary: This study aimed to describe the racial/ethnic differences in utilization and outcomes of TEVAR. The findings showed differential distribution of thoracic indication and comorbidities among different racial/ethnic groups in TEVAR. However, after adjusting for covariates, racial disparities did not appear to be associated with in-hospital mortality.

JOURNAL OF CARDIAC SURGERY (2022)

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Review Surgery

Current state and future directions of genomic medicine in aortic dissection: A path to prevention and personalized care

Alana C. Cecchi et al.

Summary: Aortic dissection is a high-risk condition with significant impact on mortality, morbidity, and healthcare burden. Integrating genomic information is crucial for stratifying risk and preventing aortic dissection, but implementation barriers need to be addressed. Collaborative efforts are being made to define research priorities and improve patient outcomes in aortic dissection prevention and genomic medicine services.

SEMINARS IN VASCULAR SURGERY (2022)

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Article Hematology

Preventing Cholesterol-Induced Perk (Protein Kinase RNA-Like Endoplasmic Reticulum Kinase) Signaling in Smooth Muscle Cells Blocks Atherosclerotic Plaque Formation

Abhijnan Chattopadhyay et al.

Summary: This study reveals that hypercholesterolemia drives complex phenotypic modulation of vascular smooth muscle cells (SMCs) and leads to atherosclerotic plaque formation. Deficiency of Perk in SMCs reduces plaque formation and prevents migration of SMCs from the medial layer of the aorta.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2022)

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Article Cardiac & Cardiovascular Systems

Delayed sternal closure for intractable bleeding after acute type A aortic dissection repair: outcomes and risk factors analyses

Chun-Yu Lin et al.

Summary: Delayed sternal closure (DSC) is an efficient technique for stabilizing patients with intractable bleeding after acute type A aortic dissection (ATAAD) repair surgery. This retrospective study compared the outcomes and risk factors in patients who underwent DSC versus primary sternal closure (PSC) during ATAAD repair surgery. The study found that the DSC group had higher rates of hemopericardium and preoperative malperfusion, as well as longer cardiopulmonary bypass and aortic clamping times and a higher rate of intraoperative extracorporeal membrane oxygenation (ECMO) support. However, there were no significant differences in in-hospital mortality rates, 5-year survival rates, and freedom from reoperation rates between the DSC and PSC groups. Hemopericardium, preoperative malperfusion, and intraoperative ECMO support were identified as risk factors for implementing DSC.

JOURNAL OF CARDIOTHORACIC SURGERY (2022)

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Article Cardiac & Cardiovascular Systems

Current status of open surgery for acute type A aortic dissection in Japan

Yutaka Okita et al.

Summary: Approximately 30,000 patients with acute aortic dissection underwent open surgery in the past six years according to the nationwide Japanese database. The number of operations has increased, and in-hospital mortality has been stable or decreasing.

JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY (2022)

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Review Cardiac & Cardiovascular Systems

Risk Stratification in Bicuspid Aortic Valve Aortopathy: Emerging Evidence and Future Perspectives

Alessandro Della Corte et al.

Summary: The current management of aortic dilatation associated with congenital bicuspid aortic valve is moving beyond dimensional parameters to investigate phenotypic criteria, flow-related metrics, and circulating biomarkers for risk stratification. Research is focusing on identifying severe root phenotypes and exploring the potential use of four-dimensional-flow magnetic resonance imaging and circulating molecules as predictors for aortopathy. This review highlights the latest progress in understanding the risk stratification of bicuspid aortic valve aortopathy.

CURRENT PROBLEMS IN CARDIOLOGY (2021)

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Article Cardiac & Cardiovascular Systems

Gender-related differences in patients with acute aortic dissection type A

Bartosz Rylski et al.

Summary: Acute aortic dissection type A occurs almost twice as frequently in men compared to women. Women with this condition tend to be older, while men are more commonly diagnosed with visceral and renal malperfusion, and receive aortic root replacements more frequently. Despite differences in presentation and treatment, the outcomes of acute aortic dissection type A are similar in both genders.

JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY (2021)

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Article Surgery

Cause-specific mortality of type B aortic dissection and assessment of competing risks of mortality

Lisa Hysa et al.

Summary: TBAD is associated with high 10-year mortality. Patients with aorta-related and nonaorta-related mortality have different clinical characteristics, and there are variations in causes of death across different age groups.

JOURNAL OF VASCULAR SURGERY (2021)

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Article Cardiac & Cardiovascular Systems

Chronobiological patterns of acute aortic dissection in central China

Liangtao Xia et al.

Summary: The study found significant seasonal, monthly, and circadian patterns in the onset of AAD. Patients with AAD of different Stanford-type dissections, sexes, ages, and hypertension statuses may exhibit different circadian variations. These findings could provide valuable insights into identifying triggers and preventing AAD.

HEART (2021)

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Review Substance Abuse

All-cause and cause-specific mortality among people with regular or problematic cocaine use: a systematic review and meta-analysis

Amy Peacock et al.

Summary: There are elevated rates of mortality among people with regular or problematic cocaine use for traumatic deaths and deaths attributable to infectious disease.

ADDICTION (2021)

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Article Hematology

Cholesterol-Induced Phenotypic Modulation of Smooth Muscle Cells to Macrophage/Fibroblast-like Cells Is Driven by an Unfolded Protein Response

Abhijnan Chattopadhyay et al.

Summary: The study found that vascular smooth muscle cells undergo phenotypic switching and express macrophage and fibroblast markers under cholesterol exposure. This switching is associated with the activation of the endoplasmic reticulum unfolded protein response, and blocking this response prevents the phenotypic transition.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2021)

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Article Cardiac & Cardiovascular Systems

2020 ACC/AHA Guideline for the Management of Patients With Valvular Heart Disease: Executive Summary A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines

Catherine M. Otto et al.

Summary: This executive summary of the valvular heart disease guideline provides recommendations and supporting documentation for clinicians to diagnose and manage valvular heart disease. It includes updated recommendations with newer options for diagnosis and treatment, focusing on diagnostic work-up, the timing and choice of surgical and catheter interventions, and recommendations for medical therapy.

CIRCULATION (2021)

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Review Cardiac & Cardiovascular Systems

Thoracic Aortic Aneurysm A Clinical Review

Ethan M. Senser et al.

CARDIOLOGY CLINICS (2021)

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Article Respiratory System

Obstructive sleep apnoea and the progression of thoracic aortic aneurysm: a prospective cohort study

Thomas Gaisl et al.

Summary: This study found that OSA may be a modest but independent risk factor for faster TAA expansion, potentially contributing to life-threatening complications in aortic disease. There was no association between OSA severity and aortic events in the participants.

EUROPEAN RESPIRATORY JOURNAL (2021)

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Article Cardiac & Cardiovascular Systems

Pregnancy outcome in thoracic aortic disease data from the Registry Of Pregnancy And Cardiac disease

Laurence Campens et al.

Summary: This study analyzed 189 pregnant women with thoracic aortic disease out of 5739 women with pre-existing cardiac disease. The results showed that most pregnant women with thoracic aortic disease had good maternal and fetal outcomes when following current guidelines during pregnancy.

HEART (2021)

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Article Surgery

Black patients have a higher burden of comorbidities but a lower risk of 30-day and 1-year mortality after thoracic endovascular aortic repair

Kanhua Yin et al.

Summary: Despite Black patients having a higher burden of comorbidities, racial disparities in perioperative outcomes and 1-year survival do not persist in TEVAR.

JOURNAL OF VASCULAR SURGERY (2021)

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Editorial Material Urology & Nephrology

Re: Short-term Ciprofloxacin Prophylaxis for Prostate Biopsy and Risk of Aortic Aneurysm. Nationwide, Population-based Cohort Study

Magnus J. Grabe

EUROPEAN UROLOGY (2021)

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Review Cardiac & Cardiovascular Systems

Epidemiology and management of aortic disease: aortic aneurysms and acute aortic syndromes

Eduardo Bossone et al.

Summary: The aorta, as the 'greatest artery', can be affected by a wide range of acute and chronic factors, leading to increased wall stress. Despite advances in diagnostic and therapeutic interventions, the burden of aortic diseases remains high, highlighting the need for preventive strategies.

NATURE REVIEWS CARDIOLOGY (2021)

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Article Surgery

Association of Fluoroquinolone Use With Short-term Risk of Development of Aortic Aneurysm

Emily R. Newton et al.

Summary: This study showed an increased incidence of aortic aneurysm formation in US adults after fluoroquinolone use, particularly in adults aged 35 years or older, regardless of sex and comorbidities, indicating that caution should be taken in the use of fluoroquinolones in all adults.

JAMA SURGERY (2021)

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Review Cardiac & Cardiovascular Systems

Aortitis: recent advances, current concepts and future possibilities

Dan Pugh et al.

Summary: Aortitis refers to inflammation of the aorta, which can have infectious and non-infectious causes, leading to a wide spectrum of disease presentation. Different subtypes of aortitis may require specific management strategies and show distinct outcomes, highlighting the importance of thorough diagnostic workup and individualized patient management.

HEART (2021)

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Article Peripheral Vascular Disease

Clinical Features and Outcomes of Pregnancy-Related Acute Aortic Dissection

A.C. Braverman et al.

JOURNAL OF VASCULAR SURGERY (2021)

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Article Environmental Sciences

Risk of Aortic Aneurysm and Dissection in Patients with Tuberculosis: A Nationwide Population-Based Cohort Study

Ming-Tsung Chen et al.

Summary: This study found that patients with tuberculosis have a higher risk of aortic aneurysm and aortic dissection, especially in cases of shorter duration of illness and different types of tuberculosis. Physicians should consider the development of aortic aneurysm and aortic dissection in tuberculosis patients during treatment.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2021)

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Review Cardiac & Cardiovascular Systems

Update on the genetic risk for thoracic aortic aneurysms and acute aortic dissections: implications for clinical care

Dianna M. Milewicz et al.

Summary: Genetic variation plays a significant role in predisposing individuals to thoracic aortic aneurysms and dissections, with genetic testing now considered an integral part of clinical evaluation for patients with thoracic aortic disease.

JOURNAL OF CARDIOVASCULAR SURGERY (2021)

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Article Cardiac & Cardiovascular Systems

Effects of Fluoroquinolones on Outcomes of Patients With Aortic Dissection or Aneurysm

Shao-Wei Chen et al.

Summary: The use of fluoroquinolones in patients with aortic dissection or aneurysm is associated with a higher risk of adverse outcomes compared to amoxicillin.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2021)

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Editorial Material Cardiac & Cardiovascular Systems

Fluoroquinolones in Patients With Aortic Aneurysms or Dissections Pouring Gasoline on a Fire

Scott A. LeMaire

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2021)

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Article Urology & Nephrology

Short-term ciprofloxacin prophylaxis for prostate biopsy and risk of aortic aneurysm. Nationwide, population-based cohort study

Karl-Johan Lundstrom et al.

Summary: This study examined the risk of aortic aneurysm after short-term ciprofloxacin as prophylaxis for prostate biopsy, and found that short-term ciprofloxacin was not associated with an increased risk of aortic aneurysm. However, an increased risk of aortic aneurysm was observed in men diagnosed with high-risk prostate cancer, likely due to detection bias caused by more commonly performed imaging in these men.

SCANDINAVIAN JOURNAL OF UROLOGY (2021)

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Article Cardiac & Cardiovascular Systems

Implications of abnormal ascending aorta geometry for risk prediction of acute type A aortic dissection

Alessandro Della Corte et al.

Summary: This study identified specific geometric characteristics of the ascending aorta associated with ATAAD, such as the asc-arch angle and total length. Patients with ATAAD showed significantly elongated ascending aortas and uniquely narrower angles, which can help differentiate ATAAD from a normal aorta.

EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY (2021)

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Article Cardiac & Cardiovascular Systems

Pregnancy-Related Aortic Complications in Women With Marfan Syndrome

Nupoor Narula et al.

Summary: The study found that there is an increased risk of aortic dissection during pregnancy in Marfan syndrome patients, especially in those unaware of their diagnosis. Additionally, most patients maintained stable aortic dimensions during pregnancy, leading to favorable pregnancy outcomes.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2021)

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Article Surgery

Characterization of syndromic, nonsyndromic familial, and sporadic type B aortic dissection

Sherene Shalhub et al.

Summary: Genetic factors may influence Type B aortic dissection (TBAD). A study of 389 patients revealed that 27.9% had a heritable cause, with syndromic and nonsyndromic familial TBAD being more common. These patients typically presented symptoms at a younger age and had higher mortality rates during treatment.

JOURNAL OF VASCULAR SURGERY (2021)

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Article Respiratory System

Prevalence of Obstructive Sleep Apnea in Patients with Thoracic Aortic Aneurysm: A Prospective, Parallel Cohort Study

Thomas Gaisl et al.

RESPIRATION (2020)

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Article Cardiac & Cardiovascular Systems

Analysis of Acute Type A Aortic Dissection in Japan Registry of Aortic Dissection (JRAD)

Yosuke Inoue et al.

ANNALS OF THORACIC SURGERY (2020)

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Article Pediatrics

The incidence of collagen-associated adverse events in pediatric population with the use of fluoroquinolones: a nationwide cohort study in Taiwan

Pei-Han Yu et al.

BMC PEDIATRICS (2020)

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Review Cardiac & Cardiovascular Systems

Etiology, Diagnosis and Management of Aortitis

Sanjiv Sharma et al.

CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY (2020)

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Article Cardiac & Cardiovascular Systems

Inherited Thoracic Aortic Disease New Insights and Translational Targets

Alexander J. Fletcher et al.

CIRCULATION (2020)

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Review Surgery

Pregnancy and Aortic Dissection

Carlota F. Prendes et al.

EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY (2020)

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Article Multidisciplinary Sciences

Higher admission rates and in-hospital mortality for acute type A aortic dissection during Influenza season: a single center experience

Carmel Ashur et al.

SCIENTIFIC REPORTS (2020)

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Article Cardiac & Cardiovascular Systems

Progesterone promotes endothelial nitric oxide synthase expression through enhancing nuclear progesterone receptor-SP-1 formation

Yuehua You et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2020)

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Letter Cardiac & Cardiovascular Systems

Long-Term Outcome and Prognosis Factors of Isolated Aortitis

Yasmina Ferfar et al.

CIRCULATION (2020)

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Editorial Material Cardiac & Cardiovascular Systems

Nosology Spectrum of the Bicuspid Aortic Valve Condition Complex-Presentation Valvulo-Aortopathy

Hector I. Michelena et al.

CIRCULATION (2020)

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Article Cardiac & Cardiovascular Systems

Sex differences and temporal trends in aortic dissection: a population-based study of incidence, treatment strategies, and outcome in Swedish patients during 15 years

Christian Smedberg et al.

EUROPEAN HEART JOURNAL (2020)

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Article Cardiac & Cardiovascular Systems

Pregnancy-associated arterial dissections: a nationwide cohort study

Sebastian E. Beyer et al.

EUROPEAN HEART JOURNAL (2020)

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Article Cardiac & Cardiovascular Systems

Sex-specific risk factors for early mortality and survival after surgery of acute aortic dissection type a: a retrospective observational study

Christine Friedrich et al.

JOURNAL OF CARDIOTHORACIC SURGERY (2020)

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Review Cardiac & Cardiovascular Systems

Embryonic development of bicuspid aortic valves

Maria Teresa Soto-Navarrete et al.

PROGRESS IN CARDIOVASCULAR DISEASES (2020)

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Review Cardiac & Cardiovascular Systems

Genetics in bicuspid aortic valve disease: Where are we?

Katia Bravo-Jaimes et al.

PROGRESS IN CARDIOVASCULAR DISEASES (2020)

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Editorial Material Medicine, General & Internal

Observational Study Design Challenges-The Case of Fluoroquinolones and Aortic Disease

Raphaela Lipinsky DeGette et al.

JAMA INTERNAL MEDICINE (2020)

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Article Medicine, General & Internal

Association of Fluoroquinolones With the Risk of Aortic Aneurysm or Aortic Dissection

Chandrasekar Gopalakrishnan et al.

JAMA INTERNAL MEDICINE (2020)

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Article Medicine, General & Internal

Association of Infections and Use of Fluoroquinolones With the Risk of Aortic Aneurysm or Aortic Dissection

Yaa-Hui Dong et al.

JAMA INTERNAL MEDICINE (2020)

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Review Cardiac & Cardiovascular Systems

Cocaine-Related Aortic Dissection: what do we know?

Dustin Greve et al.

BRAZILIAN JOURNAL OF CARDIOVASCULAR SURGERY (2020)

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Article Physiology

A validated mouse model capable of recapitulating the protective effects of female sex hormones on ascending aortic aneurysms and dissections (AADs)

Xiaoyan Qi et al.

PHYSIOLOGICAL REPORTS (2020)

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Article Cardiac & Cardiovascular Systems

Pregnancy-associated arterial dissections: a nationwide cohort study

Sebastian E. Beyer et al.

EUROPEAN HEART JOURNAL (2020)

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Article Cardiac & Cardiovascular Systems

Induction of human aortic myofibroblast-mediated extracellular matrix dysregulation: Apotential mechanism of fluoroquinolone-associated aortopathy

David G. Guzzardi et al.

JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY (2019)

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Article Cardiac & Cardiovascular Systems

Genetics of Thoracic and Abdominal Aortic Diseases Aneurysms, Dissections, and Ruptures

Amelie Pinard et al.

CIRCULATION RESEARCH (2019)

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Article Surgery

Cocaine use is associated with worse outcomes in patients treated with thoracic endovascular repair for type B aortic dissection

Halim Yammine et al.

JOURNAL OF VASCULAR SURGERY (2019)

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Article Rheumatology

Outcomes Among 196 Patients With Noninfectious Proximal Aortitis

Alison H. Clifford et al.

ARTHRITIS & RHEUMATOLOGY (2019)

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Review Radiology, Nuclear Medicine & Medical Imaging

Predictive imaging for thoracic aortic dissection and rupture: moving beyond diameters

Bouke P. Adriaans et al.

EUROPEAN RADIOLOGY (2019)

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Article Multidisciplinary Sciences

High progesterone levels are associated with family history of premature coronary artery disease in young healthy adult men

Tadeusz Osadnik et al.

PLOS ONE (2019)

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Article Genetics & Heredity

Sleep apnea and the impact on cardiovascular risk in patients with Marfan syndrome

Laura Muino-Mosquera et al.

MOLECULAR GENETICS & GENOMIC MEDICINE (2019)

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Review Pharmacology & Pharmacy

An evaluation of reports of ciprofloxacin, levofloxacin, and moxifloxacin-association neuropsychiatric toxicities, long-term disability, and aortic aneurysms/dissections disseminated by the Food and Drug Administration and the European Medicines Agency

Andrew C. Bennett et al.

EXPERT OPINION ON DRUG SAFETY (2019)

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Article Medicine, Research & Experimental

Type 2 diabetes mellitus reduces clinical complications and mortality in Stanford type B aortic dissection after thoracic endovascular aortic repair: A 3-year follow-up study

Hongtao Liu et al.

LIFE SCIENCES (2019)

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Article Critical Care Medicine

Estimation of the global prevalence and burden of obstructive sleep apnoea: a literature-based analysis

Adam V. Benjafield et al.

LANCET RESPIRATORY MEDICINE (2019)

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Article Cardiac & Cardiovascular Systems

Ascending Aortic Length and Risk of Aortic Adverse Events The Neglected Dimension

Jinlin Wu et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2019)

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Review Cardiac & Cardiovascular Systems

Clinical and pathologic findings of aortic dissection at autopsy: Review of 336 cases over nearly 6 decades

Nick Huynh et al.

AMERICAN HEART JOURNAL (2019)

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Article Peripheral Vascular Disease

Prevailing Influenza Activity and Acute Aortic Dissection Seasonality

Harleen Sandhu et al.

EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY (2019)

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Letter Pharmacology & Pharmacy

Ciprofloxacin-Associated Hypoglycemia

Prabhsimranjot Singh et al.

AMERICAN JOURNAL OF THERAPEUTICS (2019)

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Article Biochemistry & Molecular Biology

Obstructive sleep apnea syndrome promotes the progression of aortic dissection via a ROS-HIF-1α-MMPs associated pathway

Wanjun Liu et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2019)

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Article Peripheral Vascular Disease

2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NM CNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines

Paul K. Whelton et al.

HYPERTENSION (2018)

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Article Genetics & Heredity

Variants of Unknown Significance in Genes Associated with Heritable Thoracic Aortic Disease Can Be Low Penetrant Risk Variants

Callie S. Kwartler et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2018)

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Article Cardiac & Cardiovascular Systems

Prevention of Aortic Dissection Suggests a Diameter Shift to a Lower Aortic Size Threshold for Intervention

Ahmed M. Mansour et al.

CARDIOLOGY (2018)

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Article Cardiac & Cardiovascular Systems

Aortic elongation in aortic aneurysm and dissection: the Tubingen Aortic Pathoanatomy (TAIPAN) project

Tobias Krueger et al.

EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY (2018)

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Article Cardiac & Cardiovascular Systems

Aortic elongation part I: the normal aortic ageing process

Bouke P. Adriaans et al.

HEART (2018)

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Article Cardiac & Cardiovascular Systems

Epidemiology and management of thoracic aortic dissections and thoracic aortic aneurysms in Ontario, Canada: A population-based study

R. Scott McClure et al.

JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY (2018)

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Article Cardiac & Cardiovascular Systems

Low rate of reoperations after acute type A aortic dissection repair from The Nordic Consortium Registry

Emily Pan et al.

JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY (2018)

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Article Surgery

Ethnic disparities in outcomes of patients with complicated type B aortic dissection

Halim Yammine et al.

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Article Cardiac & Cardiovascular Systems

Muerte súbita por disección de aorta torácica en jóvenes: estudio multicéntrico forense

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REVISTA ESPANOLA DE CARDIOLOGIA (2018)

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Article Peripheral Vascular Disease

Obstructive sleep apnea and risk of aortic dissection: A meta-analysis of observational studies

Xiushi Zhou et al.

VASCULAR (2018)

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Article Medicine, Legal

Aortic dissection in cocaine abuse: A fatal case

S. D'Errico et al.

JOURNAL OF FORENSIC AND LEGAL MEDICINE (2018)

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Article Medicine, General & Internal

Fluoroquinolone use and risk of aortic aneurysm and dissection: nationwide cohort study

Bjorn Pasternak et al.

BMJ-BRITISH MEDICAL JOURNAL (2018)

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Article Cardiac & Cardiovascular Systems

Clinical differences between men and women undergoing surgery for acute Type A aortic dissection

Tomoaki Suzuki et al.

INTERACTIVE CARDIOVASCULAR AND THORACIC SURGERY (2018)

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Article Medicine, General & Internal

Fluoroquinolone use and risk of aortic aneurysm and dissection: nationwide cohort study

Bjorn Pasternak et al.

BMJ-BRITISH MEDICAL JOURNAL (2018)

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Article Cardiac & Cardiovascular Systems

Insights From the International Registry of Acute Aortic Dissection A 20-Year Experience of Collaborative Clinical Research

Arturo Evangelista et al.

CIRCULATION (2018)

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Article Cardiac & Cardiovascular Systems

2018 ESC Guidelines for the management of cardiovascular diseases during pregnancy

Vera Regitz-Zagrosek et al.

EUROPEAN HEART JOURNAL (2018)

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Article Cardiac & Cardiovascular Systems

Clinical Validity of Genes for Heritable Thoracic Aortic Aneurysm and Dissection

Marjolijn Renard et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2018)

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Article Cardiac & Cardiovascular Systems

Oral Fluoroquinolone and the Risk of Aortic Dissection

Chien-Chang Lee et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2018)

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Article Surgery

Effect of Ciprofloxacin on Susceptibility to Aortic Dissection and Rupture in Mice

Scott A. LeMaire et al.

JAMA SURGERY (2018)

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Article Peripheral Vascular Disease

Negative Association of Diabetes With Thoracic Aortic Dissection and Aneurysm

Hisato Takagi et al.

ANGIOLOGY (2017)

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Article Cardiac & Cardiovascular Systems

Aortic elongation and the risk for dissection: the Tubingen Aortic Pathoanatomy (TAIPAN) project

Tobias Krueger et al.

EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY (2017)

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Review Cardiac & Cardiovascular Systems

Contemporary natural history of bicuspid aortic valve disease: a systematic review

Ahmad Masri et al.

HEART (2017)

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Article Neurosciences

Seasonal Variation in Spontaneous Cervical Artery Dissection: Comparing between UK and Australian Sites

Lucy C. Thomas et al.

JOURNAL OF STROKE & CEREBROVASCULAR DISEASES (2017)

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Cardiovascular operations for Loeys-Dietz syndrome: Intermediate-term results

Nishant D. Patel et al.

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Sex, pregnancy and aortic disease in Marfan syndrome

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PLOS ONE (2017)

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Review Medicine, General & Internal

Acute aortic dissection: pathogenesis, risk factors and diagnosis

Gawinecka Joanna et al.

SWISS MEDICAL WEEKLY (2017)

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A meta-analysis of weekend admission and surgery for aortic rupture and dissection

Hisato Takagi et al.

VASCULAR MEDICINE (2017)

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Article Neurosciences

Seasonal Variation in Spontaneous Cervical Artery Dissection: Comparing between UK and Australian Sites

Lucy C. Thomas et al.

JOURNAL OF STROKE & CEREBROVASCULAR DISEASES (2017)

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Differences in the Thoracic Aorta by Region and Sex in a Murine Model of Marfan Syndrome

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FRONTIERS IN PHYSIOLOGY (2017)

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Article Rehabilitation

Seasonal variation in cervical artery dissection in the Hunter New England region, New South Wales, Australia: A retrospective cohort study

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MUSCULOSKELETAL SCIENCE AND PRACTICE (2017)

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Article Clinical Neurology

The Relative Impact of Obstructive Sleep Apnea and Hypertension on the Structural and Functional Changes of the Thoracic Aorta

Lee Li-Ching et al.

SLEEP (2017)

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Long-Term Outcomes and Prognostic Factors of Complications in Takayasu Arteritis A Multicenter Study of 318 Patients

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CIRCULATION (2017)

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Article Cardiac & Cardiovascular Systems

Aortic Dissection in Pregnancy: Management Strategy and Outcomes

Jun-Ming Zhu et al.

ANNALS OF THORACIC SURGERY (2017)

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Effects of Gender Differences on Short-term Outcomes in Patients with Type B Aortic Dissection

Nathan L. Liang et al.

ANNALS OF VASCULAR SURGERY (2017)

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Article Cardiac & Cardiovascular Systems

Chronobiology of Acute Aortic Dissection in the Marfan Syndrome (from the National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions and the International Registry of Acute Aortic Dissection)

Hasan K. Siddiqi et al.

AMERICAN JOURNAL OF CARDIOLOGY (2017)

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Prevalence of Type A Acute Aortic Dissection in Patients. With Out-Of-Hospital Cardiopulmonary Arrest

Yoshihiro Tanaka et al.

AMERICAN JOURNAL OF CARDIOLOGY (2016)

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Vascular diseases: aortitis, aortic aneurysms, and vascular calcification

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CARDIOVASCULAR PATHOLOGY (2016)

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Recurrent Aortic Dissection Observations From the International Registry of Aortic Dissection

Eric M. Isselbacher et al.

CIRCULATION (2016)

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Pregnancy and the Risk of Aortic Dissection or Rupture A Cohort-Crossover Analysis

Hooman Kamel et al.

CIRCULATION (2016)

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Review Biochemistry & Molecular Biology

So Much Cholesterol: the unrecognized importance of smooth muscle cells in atherosclerotic foam cell formation

Joshua A. Dubland et al.

CURRENT OPINION IN LIPIDOLOGY (2016)

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Article Cardiac & Cardiovascular Systems

Ascending aortic elongation and the risk of dissection

Tobias Krueger et al.

EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY (2016)

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Letter Cardiac & Cardiovascular Systems

Snoring but not sleepiness is associated with increased aortic root diameter in hypertensive patients. The SLEEPART study

Jean-Philippe Baguet et al.

INTERNATIONAL JOURNAL OF CARDIOLOGY (2016)

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Review Medicine, General & Internal

Acute Aortic Dissection and Intramural Hematoma A Systematic Review

Firas F. Mussa et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2016)

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Article Cardiac & Cardiovascular Systems

Risk of Aortic Dissection in the Moderately Dilated Ascending Aorta

Joon Bum Kim et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2016)

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Article Surgery

Natural history and risk factors for rupture of thoracic aortic arch aneurysms

Rachel S. Yiu et al.

JOURNAL OF VASCULAR SURGERY (2016)

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Article Medicine, General & Internal

Sex-Related Differences Between Patients With Symptomatic Acute Aortic Dissection

Buamina Maitusong et al.

MEDICINE (2016)

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Topoisomerase Inhibitors: Fluoroquinolone Mechanisms of Action and Resistance

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COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2016)

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Article Cardiac & Cardiovascular Systems

Aortic Complications Associated With Pregnancy in Marfan Syndrome: The NHLBI National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions (GenTAC)

Mary J. Roman et al.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2016)

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Article Cardiac & Cardiovascular Systems

Syphilis as a Cause of Thoracic Aortic Aneurysm

William C. Roberts et al.

AMERICAN JOURNAL OF CARDIOLOGY (2015)

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Article Cardiac & Cardiovascular Systems

Current Clinical Features of New Patients With Takayasu Arteritis Observed From Cross-Country Research in Japan Age and Sex Specificity

Yoshiko Watanabe et al.

CIRCULATION (2015)

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Article Cardiac & Cardiovascular Systems

Long-Term Risk for Aortic Complications After Aortic Valve Replacement in Patients With Bicuspid Aortic Valve Versus Marfan Syndrome

Shinobu Itagaki et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2015)

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Article Cardiac & Cardiovascular Systems

Presentation, Diagnosis, and Outcomes of Acute Aortic Dissection 17-Year Trends From the International Registry of Acute Aortic Dissection

Linda A. Pape et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2015)

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Article Cardiac & Cardiovascular Systems

Gender differences in patients undergoing surgery for acute type A aortic dissection

Toshihiro Fukui et al.

JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY (2015)

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Article Medicine, General & Internal

Aortic dissection in pregnancy in England: an incidence study using linked national databases

Amitava Banerjee et al.

BMJ OPEN (2015)

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Fluoroquinolones and collagen associated severe adverse events: a longitudinal cohort study

Nick Daneman et al.

BMJ OPEN (2015)

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A deleterious gene-by-environment interaction imposed by calcium channel blockers in Marfan syndrome

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ELIFE (2015)

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Article Cardiac & Cardiovascular Systems

Risk Profiles for Aortic Dissection and Ruptured or Surgically Treated Aneurysms: A Prospective Cohort Study

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JOURNAL OF THE AMERICAN HEART ASSOCIATION (2015)

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Article Medicine, General & Internal

Risk of Aortic Dissection and Aortic Aneurysm in Patients Taking Oral Fluoroquinolone

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JAMA INTERNAL MEDICINE (2015)

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Advanced complicated diabetes mellitus is associated with a reduced risk of thoracic and abdominal aortic aneurysm rupture: a population-based cohort study

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DIABETES-METABOLISM RESEARCH AND REVIEWS (2015)

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Clinical Features and Radiological Findings in Large Vessel Vasculitis: Are Takayasu Arteritis and Giant Cell Arteritis 2 Different Diseases or a Single Entity?

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Inflammatory ascending aortic disease: Perspectives from pathology

Joseph J. Maleszewski

JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY (2014)

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Article Medicine, General & Internal

Cocaine-related Aortic Dissection: Lessons from the International Registry of Acute Aortic Dissection

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AMERICAN JOURNAL OF MEDICINE (2014)

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Acute Aortic Dissection Type A Age-related Management and Outcomes Reported in the German Registry for Acute Aortic Dissection Type A (GERAADA) of Over 2000 Patients

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Article Surgery

Obstructive Sleep Apnea Syndrome: A Risk Factor for Stanford's Type B Aortic Dissection

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ANNALS OF VASCULAR SURGERY (2014)

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The Impact of Weather Factors, Moon Phases, and Seasons on Abdominal Aortic Aneurysm Rupture

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ANNALS OF VASCULAR SURGERY (2014)

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Article Cardiac & Cardiovascular Systems

Contribution of Intimal Smooth Muscle Cells to Cholesterol Accumulation and Macrophage-Like Cells in Human Atherosclerosis

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CIRCULATION (2014)

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Article Cardiac & Cardiovascular Systems

2014 ESC Guidelines on the diagnosis and treatment of aortic diseases

Raimund Erbel et al.

EUROPEAN HEART JOURNAL (2014)

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Article Biochemistry & Molecular Biology

The protective effects of 17beta-estradiol against ischemia-reperfusion injury and its effect on pacing postconditioning protection to the heart

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JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY (2014)

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Article Cardiac & Cardiovascular Systems

How Does the Ascending Aorta Geometry Change When It Dissects?

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JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2014)

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Article Cardiac & Cardiovascular Systems

Clinical features of acute aortic dissection from the Registry of Aortic Dissection in China

Weiguang Wang et al.

JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY (2014)

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Article Cardiac & Cardiovascular Systems

Effect of Statin Drugs on Thoracic Aortic Aneurysms

Louis H. Stein et al.

AMERICAN JOURNAL OF CARDIOLOGY (2013)

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Article Genetics & Heredity

Severe obstructive sleep apnea in loeys-dietz syndrome successfully treated using continuous positive airway pressure

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AMERICAN JOURNAL OF MEDICAL GENETICS PART A (2013)

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Acute Aortic Dissection in Blacks: Insights from the International Registry of Acute Aortic Dissection

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Cocaine and Specific Cocaine Metabolites Induce von Willebrand Factor Release From Endothelial Cells in a Tissue-Specific Manner

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2012 Revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides

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ARTHRITIS AND RHEUMATISM (2013)

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Population-Based Study of Incidence and Outcome of Acute Aortic Dissection and Premorbid Risk Factor Control 10-Year Results From the Oxford Vascular Study

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CIRCULATION (2013)

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Editorial Material Cardiac & Cardiovascular Systems

FDG-PET/CT in the diagnosis of aortitis in fever of unknown origin with severe aortic incompetence

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HEART (2013)

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Article Peripheral Vascular Disease

Seasonal Blood Pressure Changes An Independent Relationship With Temperature and Daylight Hours

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HYPERTENSION (2013)

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18F-fluorodeoxyglucose-positron emission tomography scanning is a useful tool for therapy evaluation of arterial aneurysm in Behcet's disease

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Article Surgery

Racial and ethnic disparities in the treatment of unruptured thoracoabdominal aortic aneurysms in the United States

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Article Surgery

Association of race and socioeconomic status with the use of endovascular repair to treat thoracic aortic diseases

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JOURNAL OF VASCULAR SURGERY (2013)

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The Impact of Obstructive Sleep Apnea on Aortic Disease in Marfan's Syndrome

Malcolm Kohler et al.

RESPIRATION (2013)

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Article Biochemistry & Molecular Biology

Protective actions of progesterone in the cardiovascular system: Potential role of membrane progesterone receptors (mPRs) in mediating rapid effects

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STEROIDS (2013)

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Article Medicine, General & Internal

Impact of Age, Sex, Obesity, and Steroid Use on Quinolone-associated Tendon Disorders

Barton L. Wise et al.

AMERICAN JOURNAL OF MEDICINE (2012)

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Article Cardiac & Cardiovascular Systems

Obstructive sleep apnea as a potential risk factor for aortic disease

Hirokazu Saruhara et al.

HEART AND VESSELS (2012)

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Aortic dissection is associated with intermittent hypoxia and re-oxygenation

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HEART AND VESSELS (2012)

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Higher mortality in patients hospitalized for acute aortic rupture or dissection during weekends

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JOURNAL OF VASCULAR SURGERY (2012)

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Bicuspid Aortic Valve: Inter-Racial Difference in Frequency and Aortic Dimensions

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JACC-CARDIOVASCULAR IMAGING (2012)

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Article Cardiac & Cardiovascular Systems

Diabetes and Reduced Risk for Thoracic Aortic Aneurysms and Dissections: A Nationwide Case-Control Study

Siddharth K. Prakash et al.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2012)

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Article Cardiac & Cardiovascular Systems

Pravastatin Reduces Marfan Aortic Dilation

Darren McLoughlin et al.

CIRCULATION (2011)

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Letter Cardiac & Cardiovascular Systems

Weekend versus weekday hospital admissions for acute heart failure

Massimo Gallerani et al.

INTERNATIONAL JOURNAL OF CARDIOLOGY (2011)

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Article Clinical Neurology

FLUOROQUINOLONES INFLUENCE THE INTRACELLULAR CALCIUM HANDLING IN INDIVIDUALS SUSCEPTIBLE TO MALIGNANT HYPERTHERMIA

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MUSCLE & NERVE (2011)

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Review Cardiac & Cardiovascular Systems

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Scott A. LeMaire et al.

NATURE REVIEWS CARDIOLOGY (2011)

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Article Clinical Neurology

Increased Aortic Root Size is Associated with Nocturnal Hypoxia and Diastolic Blood Pressure in Obstructive Sleep Apnea

Jean-Philippe Baguet et al.

SLEEP (2011)

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Editorial Material Rheumatology

Idiopathic aortitis: an underrecognized vasculitis

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ARTHRITIS RESEARCH & THERAPY (2011)

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Article Medicine, Legal

Aortic dissection and cocaine use

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JOURNAL OF FORENSIC AND LEGAL MEDICINE (2011)

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The American College of Rheumatology 1990 criteria for the classification of giant cell arteritis

Gene G. Hunder et al.

ARTHRITIS AND RHEUMATISM (2010)

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Article Cardiac & Cardiovascular Systems

Influenza virus directly infects, inflames, and resides in the arteries of atherosclerotic and normal mice

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ATHEROSCLEROSIS (2010)

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Article Cardiac & Cardiovascular Systems

2010 ACCF/AHA/AATS/ACR/ASA/SCA/SCAI/SIR/STS/SVM Guidelines for the Diagnosis and Management of Patients With Thoracic Aortic Disease - A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, American Association for Thoracic Surgery, American College of Radiology, American Stroke Association, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, Society of Interventional Radiology, Society of Thoracic Surgeons, and Society for Vascular Medicine

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CIRCULATION (2010)

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Letter Obstetrics & Gynecology

Aortic dissection in pregnancy: the incidence of a life-threatening disease

Josefine Nasiell et al.

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY (2010)

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Review Surgery

Diabetes and the Abdominal Aortic Aneurysm

S. Shantikumar et al.

EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY (2010)

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Article Biochemistry & Molecular Biology

Mitochondrial impairment contributes to cocaine-induced cardiac dysfunction: Prevention by the targeted antioxidant MitoQ

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FREE RADICAL BIOLOGY AND MEDICINE (2010)

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Article Peripheral Vascular Disease

Therapeutic Efficacy of Continuous Positive Airway Pressure in Obstructive Sleep Apnea Patients with Acute Aortic Dissection: a Case Report

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JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS (2010)

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Article Cardiac & Cardiovascular Systems

Natural History of Syphilitic Aortitis

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AMERICAN JOURNAL OF CARDIOLOGY (2009)

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Article Genetics & Heredity

Mutations in Smooth Muscle Alpha-Actin (ACTA2) Cause Coronary Artery Disease, Stroke, and Moyamoya Disease, Along with Thoracic Aortic Disease

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AMERICAN JOURNAL OF HUMAN GENETICS (2009)

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Review Rheumatology

Epidemiology of Giant Cell Arteritis and Polymyalgia Rheumatica

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ARTHRITIS CARE & RESEARCH (2009)

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Article Cardiac & Cardiovascular Systems

Diabetes Mellitus: Is It Protective against Aortic Root Dilatation?

Xiao-Feng Chen et al.

CARDIOLOGY (2009)

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Article Cardiac & Cardiovascular Systems

Outcomes of Patients With Acute Type A Aortic Intramural Hematoma

Jae-Kwan Song et al.

CIRCULATION (2009)

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Article Cardiac & Cardiovascular Systems

Weekend Versus Weekday Admission and Mortality After Acute Pulmonary Embolism

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CIRCULATION (2009)

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Article Cardiac & Cardiovascular Systems

Aortic size in acute type A dissection: implications for preventive ascending aortic replacement

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EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY (2009)

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Article Clinical Neurology

Off-Hour Admission and In-Hospital Stroke Case Fatality in the Get With The Guidelines-Stroke Program

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STROKE (2009)

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Article Respiratory System

The prevalence of obstructive sleep apnoea and its association with aortic dilatation in Marfan's syndrome

M. Kohler et al.

THORAX (2009)

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Correction Cardiac & Cardiovascular Systems

Age-Associated Elongation of the Ascending Aorta in Adults (vol 1, pg 739, 2008)

J. Sugawara et al.

JACC-CARDIOVASCULAR IMAGING (2009)

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Article Anesthesiology

Dihydropiridine calcium-channel blockers and perioperative mortality in aortic aneurysm surgery

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BRITISH JOURNAL OF ANAESTHESIA (2008)

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Article Cardiac & Cardiovascular Systems

Molecular Analysis of Cocaine-Induced Endothelial Dysfunction: Role of Endothelin-1 and Nitric Oxide

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CARDIOVASCULAR TOXICOLOGY (2008)

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Article Cardiac & Cardiovascular Systems

Reduced expansion rate of abdominal aortic aneurysms in patients with diabetes may be related to aberrant monocyte-matrix interactions

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EUROPEAN HEART JOURNAL (2008)

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Article Cardiac & Cardiovascular Systems

Age-Associated Elongation of the Ascending Aorta in Adults

Jun Sugawara et al.

JACC-CARDIOVASCULAR IMAGING (2008)

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Article Cardiac & Cardiovascular Systems

Cocaine-related acute aortic dissection: Patient demographics and clinical outcomes

Sarabjeet Singh et al.

CANADIAN JOURNAL OF CARDIOLOGY (2007)

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Article Cardiac & Cardiovascular Systems

Aortic diameter ≥5.5 cm is not a good predictor of type A aortic dissection -: Observations from the international registry of acute aortic dissection (IRAD)

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CIRCULATION (2007)

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Article Surgery

Acute aortic dissection associated with use of cocaine

Jonathan C. Daniel et al.

JOURNAL OF VASCULAR SURGERY (2007)

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Article Medicine, General & Internal

Weekend versus weekday admission and mortality from myocardial infarction

William J. Kostis et al.

NEW ENGLAND JOURNAL OF MEDICINE (2007)

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Article Cardiac & Cardiovascular Systems

NADPH oxidase inhibition prevents cocaine-induced up-regulation of xanthine oxidoreductase and cardiac dysfunction

Marc Isabelle et al.

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2007)

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Article Cardiac & Cardiovascular Systems

Weight lifting and aortic dissection: More evidence for a connection

I. Hatzaras et al.

CARDIOLOGY (2007)

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Article Microbiology

Calcium signals are affected by ciprofloxacin as a consequence of reduction of mitochondrial DNA content in Jurkat cells

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ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2006)

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Article Multidisciplinary Sciences

Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome

JP Habashi et al.

SCIENCE (2006)

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Review Immunology

Antimicrobial safety: Focus on fluoroquinolones

RC Owens et al.

CLINICAL INFECTIOUS DISEASES (2005)

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Article Cardiac & Cardiovascular Systems

Pregnancy and aortic root growth in the Marfan syndrome: a prospective study

LJ Meijboom et al.

EUROPEAN HEART JOURNAL (2005)

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Article Medicine, General & Internal

Fluoroquinolone prescribing in the United States: 1995 to 2002

JA Linder et al.

AMERICAN JOURNAL OF MEDICINE (2005)

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Article Cardiac & Cardiovascular Systems

Estrogen receptor-β mediates male-female differences in the development of pressure overload hypertrophy

M Skavdahl et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2005)

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Article Biology

Does circadian and seasonal variation in occurrence of acute aortic dissection influence in-hospital outcomes?

RH Mehta et al.

CHRONOBIOLOGY INTERNATIONAL (2005)

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Article Rheumatology

Reappraisal of the epidemiology of giant cell arteritis in Olmsted County, Minnesota, over a fifty-year period

C Salvarani et al.

ARTHRITIS & RHEUMATISM-ARTHRITIS CARE & RESEARCH (2004)

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Review Surgery

Chronobiology of rupture and dissection of aortic aneurysms

R Manfredini et al.

JOURNAL OF VASCULAR SURGERY (2004)

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Article Cardiac & Cardiovascular Systems

Bicuspid aortic valve is heritable

L Cripe et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2004)

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Article Cardiac & Cardiovascular Systems

Gender-related differences in acute aortic dissection

CA Nienaber et al.

CIRCULATION (2004)

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Article Medicine, Legal

Thoracic aortic dissection associated with cocaine abuse

C Palmiere et al.

FORENSIC SCIENCE INTERNATIONAL (2004)

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Article Critical Care Medicine

Obstructive sleep apnea and thoracic aorta dissection

G Sampol et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2003)

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Article Multidisciplinary Sciences

Transdifferentiation of mouse aortic smooth muscle cells to a macrophage-like state after cholesterol loading

JX Rong et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

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Article Cardiac & Cardiovascular Systems

Diabetes and evidence of atherosclerosis are major risk factors for adverse outcome after elective thoracic aortic surgery

C Hagl et al.

JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY (2003)

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Review Cardiac & Cardiovascular Systems

Aortic dissection in pregnancy: Analysis of risk factors and outcome

FF Immer et al.

ANNALS OF THORACIC SURGERY (2003)

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Article Surgery

Surgical mortality in patients with infected aortic aneurysms

AJ Fillmore et al.

JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS (2003)

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Letter Cardiac & Cardiovascular Systems

Variable seasonal peaks for different types of aortic dissection?

R Kobza et al.

HEART (2002)

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Article Health Care Sciences & Services

Day of the week of intensive care admission and patient outcomes - A multisite regional evaluation

MJ Barnett et al.

MEDICAL CARE (2002)

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Article Cardiac & Cardiovascular Systems

Acute aortic dissection related to crack cocaine

PY Hsue et al.

CIRCULATION (2002)

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Article Cardiac & Cardiovascular Systems

Yearly rupture or dissection rates for thoracic aortic aneurysms: Simple prediction based on size

RR Davies et al.

ANNALS OF THORACIC SURGERY (2002)

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Article Cardiac & Cardiovascular Systems

Circadian, weekly, and seasonal variation at the onset of acute aortic dissection

M Sumiyoshi et al.

AMERICAN JOURNAL OF CARDIOLOGY (2002)

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Article Cardiac & Cardiovascular Systems

Iatrogenic aortic dissection

JL Januzzi et al.

AMERICAN JOURNAL OF CARDIOLOGY (2002)

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Article Medicine, General & Internal

Mortality among patients admitted to hospitals on weekends as compared with weekdays

CM Bell et al.

NEW ENGLAND JOURNAL OF MEDICINE (2001)

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Review Medicine, General & Internal

Medical progress - Cardiovascular complications of cocaine use

RA Lange et al.

NEW ENGLAND JOURNAL OF MEDICINE (2001)

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Letter Emergency Medicine

Acute aortic dissection after cocaine and sildenafil abuse

G Famularo et al.

JOURNAL OF EMERGENCY MEDICINE (2001)

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Article Surgery

Human vascular smooth muscle cells of diabetic origin exhibit increased proliferation, adhesion, and migration

PL Faries et al.

JOURNAL OF VASCULAR SURGERY (2001)

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Article Medicine, General & Internal

Association of sleep-disordered breathing, sleep apnea, and hypertension in a large community-based study

FJ Nieto et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2000)

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Article Medicine, General & Internal

The International Registry of Acute Aortic Dissection (IRAD) - New insights into an old disease

PG Hagan et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2000)

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