4.7 Article

Berberine prevents lethal EV71 neurological infection in newborn mice

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Pharmacology & Pharmacy

Berberine: A Promising Treatment for Neurodegenerative Diseases

Ziqian Cheng et al.

Summary: Berberine, a natural alkaloid compound, has been studied for its effects on neurodegenerative diseases such as Alzheimer's, Parkinson's, and Huntington's. Current evidence shows that it can inhibit neuroinflammation, oxidative stress, and endoplasmic reticulum stress, reducing neuron damage and apoptosis. Further research is needed to fully understand the specific mechanisms involved.

FRONTIERS IN PHARMACOLOGY (2022)

Editorial Material Infectious Diseases

Protecting the most vulnerable from hand, foot, and mouth disease

Yong Wah Tan et al.

LANCET INFECTIOUS DISEASES (2021)

Article Pharmacology & Pharmacy

Cathelicidin antimicrobial peptides suppress EV71 infection via regulating antiviral response and inhibiting viral binding

Jie Yu et al.

Summary: LL-37 and CRAMP exhibit antiviral potential against non-enveloped Enterovirus 71 (EV71) infection by regulating antiviral immune response and inhibiting viral binding, providing promising candidates for peptide drug development against EV71.

ANTIVIRAL RESEARCH (2021)

Article Virology

Berberine and Obatoclax Inhibit SARS-Cov-2 Replication in Primary Human Nasal Epithelial Cells In Vitro

Finny S. Varghese et al.

Summary: The study demonstrated that berberine and obatoclax are effective against multiple isolates of SARS-CoV-2, with berberine acting on the late stage of the virus life cycle and obatoclax acting at the early stage of infection. Both compounds inhibited viral replication in primary human nasal epithelial cells, suggesting their potential as antiviral drugs against SARS-CoV-2.

VIRUSES-BASEL (2021)

Article Microbiology

Pathogenesis Study of Enterovirus 71 Using a Novel Human SCARB2 Knock-In Mouse Model

Yuefei Jin et al.

Summary: The study introduced a novel hSCARB2 knock-in mouse model using CRISPR/Cas9 system to investigate the pathogenesis of EV71 infection. The experiment showed that the KI mice exhibited neurological symptoms and pathological features similar to human EV71 encephalomyelitis, making it a valuable tool for studying the disease and developing antiviral drugs and vaccines.

MSPHERE (2021)

Article Neurosciences

Piezo1 regulates calcium oscillations and cytokine release from astrocytes

Maria Velasco-Estevez et al.

Article Medicine, Research & Experimental

Berberine increases glucose uptake and intracellular ROS levels by promoting Sirtuin 3 ubiquitination

Wei Li et al.

BIOMEDICINE & PHARMACOTHERAPY (2020)

Article Biochemistry & Molecular Biology

EV71 infection induces cell apoptosis through ROS generation and SIRT1 activation

Hongyan Li et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2020)

Review Virology

Antiviral activity of berberine

Alicja Warowicka et al.

ARCHIVES OF VIROLOGY (2020)

Article Medicine, Research & Experimental

Resveratrol-loaded nanoparticles inhibit enterovirus 71 replication through the oxidative stress-mediated ERS/autophagy pathway

Na Du et al.

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2019)

Review Biochemistry & Molecular Biology

Enterovirus-Associated Hand-Foot and Mouth Disease and Neurological Complications in Japan and the Rest of the World

Gabriel Gonzalez et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Article Immunology

Enterovirus A71 Phenotypes Causing Hand, Foot and Mouth Disease, Vietnam

Hoang Minh Tu Van et al.

EMERGING INFECTIOUS DISEASES (2019)

Review Medicine, Research & Experimental

Berberine in Cardiovascular and Metabolic Diseases: From Mechanisms to Therapeutics

Xiaojun Feng et al.

THERANOSTICS (2019)

Review Biochemistry & Molecular Biology

13 reasons why the brain is susceptible to oxidative stress

James Nathan Cobley et al.

REDOX BIOLOGY (2018)

Article Medicine, General & Internal

Hand, Foot, and Mouth Disease

Brittany Cox et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2018)

Article Pharmacology & Pharmacy

Antiviral effects of Retro-2cycl and Retro-2.1 against Enterovirus 71 in vitro and in vivo

Wenwen Dai et al.

ANTIVIRAL RESEARCH (2017)

Article Immunology

The Preferential Infection of Astrocytes by Enterovirus 71 Plays a Key Role in the Viral Neurogenic Pathogenesis

Min Feng et al.

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2016)

Article Immunology

Development of antiviral agents toward enterovirus 71 infection

Hamid Reza Pourianfar et al.

JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION (2015)

Article Infectious Diseases

Hand, foot, and mouth disease in China, 2008-12: an epidemiological study

Weijia Xing et al.

LANCET INFECTIOUS DISEASES (2014)

Article Virology

Update on enterovirus 71 infection

Peng-Nien Huang et al.

CURRENT OPINION IN VIROLOGY (2014)

Review Cell Biology

Recent developments in antiviral agents against enterovirus 71 infection

Chee Wah Tan et al.

JOURNAL OF BIOMEDICAL SCIENCE (2014)

Review Pharmacology & Pharmacy

Antiviral drug discovery for the treatment of enterovirus 71 infections

Luqing Shang et al.

ANTIVIRAL RESEARCH (2013)

Review Virology

Strategies to develop antivirals against enterovirus 71

Rei-Lin Kuo et al.

VIROLOGY JOURNAL (2013)

Review Infectious Diseases

Virology, epidemiology, pathogenesis, and control of enterovirus 71

Tom Solomon et al.

LANCET INFECTIOUS DISEASES (2010)

Review Clinical Neurology

Clinical features, diagnosis, and management of enterovirus 71

Mong How Ooi et al.

LANCET NEUROLOGY (2010)

Review Chemistry, Medicinal

Berberine: A Plant Alkaloid with Therapeutic Potential for Central Nervous System Disorders

S. K. Kulkarni et al.

PHYTOTHERAPY RESEARCH (2010)

Article Immunology

Ribavirin reduces mortality in enterovirus 71-infected mice by decreasing viral replication

Zhao-Hong Li et al.

JOURNAL OF INFECTIOUS DISEASES (2008)

Article Chemistry, Medicinal

Antiviral activity of berberine and related compounds against human cytomegalovirus

Kyoko Hayashi et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2007)