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JOURNAL OF CELL BIOLOGY (2010)
Src Signaling in Cancer Invasion
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Filamin A regulates focal adhesion disassembly and suppresses breast cancer cell migration and invasion
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JOURNAL OF EXPERIMENTAL MEDICINE (2010)
Proteomics of Hepatocellular Carcinoma: Serum Vimentin As a Surrogate Marker for Small Tumors (<= 2 cm)
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Migrastatin analogues target fascin to block tumour metastasis
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NATURE (2010)
Microtubule-binding agents: a dynamic field of cancer therapeutics
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NATURE REVIEWS DRUG DISCOVERY (2010)
Doxorubicin in Combination with a Small TGFβ Inhibitor: A Potential Novel Therapy for Metastatic Breast Cancer in Mouse Models
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PLOS ONE (2010)
Silencing or Fueling Metastasis with VEGF Inhibitors: Antiangiogenesis Revisited
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CANCER CELL (2009)
Accelerated Metastasis after Short-Term Treatment with a Potent Inhibitor of Tumor Angiogenesis
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Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis
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EphA2 Reexpression Prompts Invasion of Melanoma Cells Shifting from Mesenchymal to Amoeboid-like Motility Style
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CANCER RESEARCH (2009)
Novel anti-filamin-A antibody detects a secreted variant of filamin-A in plasma from patients with breast carcinoma and high-grade astrocytoma
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CANCER SCIENCE (2009)
New approaches to targeting the actin cytoskeleton for chemotherapy
Teresa T. Bonello et al.
FUTURE MEDICINAL CHEMISTRY (2009)
Loss of PIP5KIγ, unlike other PIP5KI isoforms, impairs the integrity of the membrane cytoskeleton in murine megakaryocytes (vol 119, pg 421, 2009)
Yanfeng Wang et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
Actinin-4 gene amplification in ovarian cancer: a candidate oncogene associated with poor patient prognosis and tumor chemoresistance
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MODERN PATHOLOGY (2009)
Role of cortical tension in bleb growth
Jean-Yves Tinevez et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits
Kornelia Polyak et al.
NATURE REVIEWS CANCER (2009)
Interference with actin dynamics is superior to disturbance of microtubule function in the inhibition of human ovarian cancer cell motility
Marcel N. A. Bijman et al.
BIOCHEMICAL PHARMACOLOGY (2008)
Expression and gene amplification of actinin-4 in invasive ductal carcinoma of the pancreas
Satoru Kikuchi et al.
CLINICAL CANCER RESEARCH (2008)
Progress in the development of matrix metalloproteinase inhibitors
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CURRENT MEDICINAL CHEMISTRY (2008)
Imaging amoeboid cancer cell motility in vivo
S. Pinner et al.
JOURNAL OF MICROSCOPY (2008)
Arp2/3 complex is important for filopodia formation, growth cone motility, and neuritogenesis in neuronal cells
Farida Korobova et al.
MOLECULAR BIOLOGY OF THE CELL (2008)
Up-regulation of Rho/ROCK signaling in sarcoma cells drives invasion and increased generation of protrusive forces
Daniel Roesel et al.
MOLECULAR CANCER RESEARCH (2008)
Direct regulation of TWIST by HIF-1α promotes metastasis
Muh-Hwa Yang et al.
NATURE CELL BIOLOGY (2008)
Tropomyosin-based regulation of the actin cytoskeleton in time and space
Peter Gunning et al.
PHYSIOLOGICAL REVIEWS (2008)
Free Brick1 Is a Trimeric Precursor in the Assembly of a Functional Wave Complex
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PLOS ONE (2008)
Markers of epithelial-mesenchymal transition and epithelial differentiation in sarcomatoid carcinoma: Utility in the differential diagnosis with sarcoma
Justin M. M. Cates et al.
APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY (2008)
Fascin expression in human embryonic, fetal, and normal adult tissue
Fa-Ren Zhang et al.
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2008)
Loss of PIP5KIγ, unlike other PIP5KI isoforms, impairs the integrity of the membrane cytoskeleton in murine megakaryocytes
Yanfeng Wang et al.
JOURNAL OF CLINICAL INVESTIGATION (2008)
On the development of models in mice of advanced visceral metastatic disease for anti-cancer drug testing
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CANCER AND METASTASIS REVIEWS (2007)
Hypoxia and cancer
M. Christiane Brahimi-Horn et al.
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Effects of Vitaxin®, a novel therapeutic in trial for metastatic bone tumors, on osteoclast functions in vitro
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JOURNAL OF CELLULAR BIOCHEMISTRY (2007)
Correlation between liver metastasis of the colocalization of actin-related protein 2 and 3 complex and WAVE2 in colorectal carcinoma
Keiichi Iwaya et al.
CANCER SCIENCE (2007)
Novel functions of vimentin in cell adhesion, migration, and signaling
Johanna Ivaska et al.
EXPERIMENTAL CELL RESEARCH (2007)
Hypoxia-driven selection of the metastatic phenotype
Richard Sullivan et al.
CANCER AND METASTASIS REVIEWS (2007)
Vimentin and epithelial-mesenchymal transition in human breast cancer - Observations in vitro and in vivo
Maria I. Kokkinos et al.
CELLS TISSUES ORGANS (2007)
Opinion - Angiogenesis: an organizing principle for drug discovery?
Judah Folkman
NATURE REVIEWS DRUG DISCOVERY (2007)
Podoplanin binds ERM proteins to activate RhoA and promote epithelial-mesenchymal transition
Ester Martin-Villar et al.
JOURNAL OF CELL SCIENCE (2006)
Meta-analysis and meta-review of thyroid cancer gene expression profiling studies identifies important diagnostic biomarkers
Obi L. Griffith et al.
JOURNAL OF CLINICAL ONCOLOGY (2006)
Calpain 2 and Src dependence distinguishes mesenchymal and amoeboid modes of tumour cell invasion: a link to integrin function
N. O. Carragher et al.
ONCOGENE (2006)
Dissection of amoeboid movement into two mechanically distinct modes
Kunito Yoshida et al.
JOURNAL OF CELL SCIENCE (2006)
Role of fascin in filopodial protrusion
Danijela Vignjevic et al.
JOURNAL OF CELL BIOLOGY (2006)
ROCK- and myosin-dependent matrix deformation enables protease-independent tumor-cell invasion in vivo
Jeffrey B. Wyckoff et al.
CURRENT BIOLOGY (2006)
Coexpression of actin-related protein 2 and Wiskott-Aldrich syndrome family verproline-homologous protein 2 in adenocarcinoma of the lung
S Semba et al.
CLINICAL CANCER RESEARCH (2006)
Tumour microenvironment - Opinion - Validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy
CM Overall et al.
NATURE REVIEWS CANCER (2006)
Radiation enhances the invasive potential of primary glioblastoma cells via activation of the rho signaling pathway
GG Zhai et al.
JOURNAL OF NEURO-ONCOLOGY (2006)
Inhibition of Rho-kinase affects astrocytoma morphology, motility, and invasion through activation of Rac1
B Salhia et al.
CANCER RESEARCH (2005)
Actinin-4 increases cell motility and promotes lymph node metastasis of colorectal cancer
K Honda et al.
GASTROENTEROLOGY (2005)
Roles of fascin in human carcinoma motility and signaling: Prospects for a novel biomarker?
Y Hashimoto et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2005)
Involvement of Arp2/3 complex in the process of colorectal carcinogenesis
T Otsubo et al.
MODERN PATHOLOGY (2004)
Tumor hypoxia correlates with metastatic tumor growth of pancreatic cancer in an orthotopic murine model
P Büchler et al.
JOURNAL OF SURGICAL RESEARCH (2004)
Actin and microtubules in cell motility: Which one is in control?
S Etienne-Manneville
TRAFFIC (2004)
The vimentin cytoskeleton regulates focal contact size and adhesion of endothelial cells subjected to shear stress
D Tsuruta et al.
JOURNAL OF CELL SCIENCE (2003)
Intravital imaging of cell movement in tumours
J Condeelis et al.
NATURE REVIEWS CANCER (2003)
Hypoxia attenuates the expression of E-cadherin via up-regulation of SNAIL in ovarian carcinoma cells
T Imai et al.
AMERICAN JOURNAL OF PATHOLOGY (2003)
Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis
E Sahai et al.
NATURE CELL BIOLOGY (2003)
Conserved microtubule-actin interactions in cell movement and morphogenesis
OC Rodriguez et al.
NATURE CELL BIOLOGY (2003)
Tumour-cell invasion and migration: Diversity and escape mechanisms
P Friedl et al.
NATURE REVIEWS CANCER (2003)
Mechanism of filopodia initiation by reorganization of a dendritic network
TM Svitkina et al.
JOURNAL OF CELL BIOLOGY (2003)
Compensation mechanism in tumor cell migration:: mesenchymal-amoeboid transition after blocking of pericellular proteolysis
K Wolf et al.
JOURNAL OF CELL BIOLOGY (2003)
Amoeboid shape change and contact guidance: T-lymphocyte crawling through fibrillar collagen is independent of matrix remodeling by MMPs and other proteases
K Wolf et al.
BLOOD (2003)
Small-molecule inhibitors of actin dynamics and cell motility
G Fenteany et al.
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2003)
Strategies for MMP inhibition in cancer:: Innovations for the post-trial era
CM Overall et al.
NATURE REVIEWS CANCER (2002)
Nucleotide exchange factor GEF-H1 mediates cross-talk between microtubules and the actin cytoskeleton
M Krendel et al.
NATURE CELL BIOLOGY (2002)
Cancer therapy - Matrix metalloproteinase inhibitors and cancer: Trials and tribulations
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SCIENCE (2002)
New functions for the matrix metalloproteinases in cancer progression
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NATURE REVIEWS CANCER (2002)
Marimastat as first-line therapy for patients with unresectable pancreatic cancer: A randomized trial
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Tamoxifen therapy for primary breast cancer and risk of contralateral breast cancer
CI Li et al.
JOURNAL OF THE NATIONAL CANCER INSTITUTE (2001)
A pilot trial of vitaxin, a humanized anti-vitronectin receptor (anti αvβ3) antibody in patients with metastatic cancer
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CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS (2001)
Development of matrix metalloproteinase inhibitors in cancer therapy
M Hidalgo et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2001)
Critical appraisal of the use of matrix metalloproteinase inhibitors in cancer treatment
S Zucker et al.
ONCOGENE (2000)