期刊
FRONTIERS IN PHARMACOLOGY
卷 13, 期 -, 页码 -出版社
FRONTIERS MEDIA SA
DOI: 10.3389/fphar.2022.1015966
关键词
tau protein; Chinese herbal medicine; dementia; oxidative stress; inflamation
资金
- Youth Project of National Natural Science Foundation of China [82101602]
- Shandong Medical and Health Technology Development Fund [202103070325]
- Shandong Province Traditional Chinese Medicine Science and Technology Project [M-2022216]
- Nursery Project of the Affiliated Tai'an City Central Hospital of Qingdao University [2022MPM06]
Dementia is a syndrome that impairs learning and memory, and there is currently no effective therapy. Traditional Chinese medicine has shown potential in treating dementia, with the ability to improve memory and cognitive dysfunctions. It has fewer adverse effects and lower costs compared to prescription drugs.
Dementia is a syndrome that impairs learning and memory. To date, there is no effective therapy for dementia. Current prescription drugs, such as cholinesterase inhibitors, fail to improve the condition of dementia and are often accompanied by severe adverse effects. In recent years, the number of studies into the use of traditional Chinese medicine (TCM) for dementia treatment has increased, revealing a formula that could significantly improve memory and cognitive dysfunctions in animal models. TCM showed fewer adverse effects, lower costs, and improved suitability for long-term use compared with currently prescribed drugs. Due to the complexity of ingredients and variations in bioactivity of herbal medicines, the multi-target nature of the traditional Chinese formula affected the outcome of dementia therapy. Innovations in TCM will create a platform for the development of new drugs for the prevention and treatment of dementia, further strengthening and enhancing the current influence of TCM.
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