期刊
FRONTIERS IN PHARMACOLOGY
卷 13, 期 -, 页码 -出版社
FRONTIERS MEDIA SA
DOI: 10.3389/fphar.2022.926507
关键词
natural products; COVID-19; SARS-CoV-2; cordycepin; gallinamide A; plitidepsin; telocinobufagin; tylophorine
资金
- Qufu Normal University, China [614901, 615201]
This paper reviews the studies on natural products in the treatment of COVID-19, highlighting their potential applications in vitro and providing essential guidance for the development of anti-SARS-CoV-2 drugs.
The devastating COVID-19 pandemic has caused more than six million deaths worldwide during the last 2 years. Effective therapeutic agents are greatly needed, yet promising magic bullets still do not exist. Numerous natural products (cordycepin, gallinamide A, plitidepsin, telocinobufagin, and tylophorine) have been widely studied and play a potential function in treating COVID-19. In this paper, we reviewed published studies (from May 2021 to April 2022) relating closely to bioactive natural products (isolated from medicinal plants, animals products, and marine organisms) in COVID-19 therapy in vitro to provide some essential guidance for anti-SARS-CoV-2 drug research and development.
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