4.7 Article

Fucoxanthin prevents breast cancer metastasis by interrupting circulating tumor cells adhesion and transendothelial migration

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Plant Sciences

A new discovery: Total Bupleurum saponin extracts can inhibit the proliferation and induce apoptosis of colon cancer cells by regulating the PI3K/Akt/mTOR pathway

Xiaojing Zhang et al.

Summary: TBSE activates the Bax/Bcl2 and caspase-9/caspase-3 cascade to induce apoptosis of human colon cancer cells in a dose-dependent manner, which is closely linked to the inhibition of the PI3K/Akt/mTOR signaling pathway.

JOURNAL OF ETHNOPHARMACOLOGY (2022)

Article Plant Sciences

Fucoxanthin extracted from Laminaria Japonica inhibits metastasis and enhances the sensitivity of lung cancer to Gefitinib

Jia Xiong Ming et al.

Summary: The active component Fucoxanthin extracted from Laminaria japonica shows significant inhibition of lung cancer cell migration and invasion. It also enhances sensitivity to Gefitinib and may work through inhibition of epithelial-to-mesenchymal transition and the PI3K/AKT/NF-kappa B pathway.

JOURNAL OF ETHNOPHARMACOLOGY (2021)

Article Oncology

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

Hyuna Sung et al.

Summary: The global cancer burden in 2020 saw an estimated 19.3 million new cancer cases and almost 10.0 million cancer deaths. Female breast cancer surpassed lung cancer as the most commonly diagnosed cancer, while lung cancer remained the leading cause of cancer death. These trends are expected to rise in 2040, with transitioning countries experiencing a larger increase compared to transitioned countries due to demographic changes and risk factors associated with globalization and a growing economy. Efforts to improve cancer prevention measures and provision of cancer care in transitioning countries will be crucial for global cancer control.

CA-A CANCER JOURNAL FOR CLINICIANS (2021)

Article Oncology

Anti-angiogenic agents - overcoming tumour endothelial cell anergy and improving immunotherapy outcomes

Zowi R. Huinen et al.

Summary: Anti-angiogenic therapy has the potential to enhance antitumor immunity by inhibiting immunosuppressive features of angiogenesis. Combinations of anti-angiogenic agents and immunotherapy have shown success in clinical trials and have been approved by the FDA. The article discusses the impact of angiogenesis on antitumor immunity, the role of endothelial cells, and the progress in combining anti-angiogenic agents with immune checkpoint inhibitors.

NATURE REVIEWS CLINICAL ONCOLOGY (2021)

Article Oncology

The ever-increasing importance of cancer as a leading cause of premature death worldwide

Freddie Bray et al.

Summary: CVD and cancer are now leading causes of premature death in 127 countries with cancer poised to overtake CVD in most countries over the course of this century. Governments must consider these transitions in disease profiles when developing cancer policies at the local level.

CANCER (2021)

Article Cell Biology

Tumour cell CD99 regulates transendothelial migration via CDC42 and actin remodelling

Aarren J. Mannion et al.

Summary: CD99 plays a complex role in tumor progression, by promoting adhesion between tumor cells and endothelial cells while inhibiting invasion and migratory activity. It negatively regulates CDC42 and cell migration, demonstrating its dual pro- and anti-tumor activities, with implications in inhibiting metastatic progression in breast cancer.

JOURNAL OF CELL SCIENCE (2021)

Article Multidisciplinary Sciences

ICAM1 initiates CTC cluster formation and trans-endothelial migration in lung metastasis of breast cancer

Rokana Taftaf et al.

Summary: CTC clusters are more efficient in mediating metastasis and ICAM1 may be a novel therapeutic target for the initiation of TNBC metastasis.

NATURE COMMUNICATIONS (2021)

Review Pharmacology & Pharmacy

Effects of Pharmacist-Led Clinical Pathway/Order Sets on Cancer Patients: A Systematic Review

Zhiyuan Tan et al.

Summary: Pharmacist-led clinical pathways/order sets (PLCOs) have positive effects on medication effectiveness, safety, and economic outcomes, including reducing hospital length of stay, decreasing medication error incidence, and increasing physicians' adherence rate. However, further optimization and expansion to other clinical areas are needed.

FRONTIERS IN PHARMACOLOGY (2021)

Review Biochemistry & Molecular Biology

Fucoxanthin, a Marine-Derived Carotenoid from Brown Seaweeds and Microalgae: A Promising Bioactive Compound for Cancer Therapy

Sarah Meresse et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Review Engineering, Biomedical

In vitro Studies of Transendothelial Migration for Biological and Drug Discovery

Alec T. Salminen et al.

FRONTIERS IN MEDICAL TECHNOLOGY (2020)

Letter Biochemistry & Molecular Biology

Achyranthes bidentata polysaccharide can safely prevent NSCLC metastasis via targeting EGFR and EMT

Chunlian Zhong et al.

SIGNAL TRANSDUCTION AND TARGETED THERAPY (2020)

Review Biotechnology & Applied Microbiology

Checkpoint CD47 Function On Tumor Metastasis And Immune Therapy

Shu Lian et al.

ONCOTARGETS AND THERAPY (2019)

Article Medicine, Research & Experimental

ZMYND8 acetylation mediates HIF-dependent breast cancer progression and metastasis

Yan Chen et al.

JOURNAL OF CLINICAL INVESTIGATION (2018)

Review Cell Biology

Molecular mechanisms of epithelial-mesenchymal transition

Samy Lamouille et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)

Review Oncology

PKB/Akt-Dependent Regulation of Cell Motility

Gongda Xue et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2013)

Review Biochemistry & Molecular Biology

The complexity of NF-κB signaling in inflammation and cancer

Bastian Hoesel et al.

MOLECULAR CANCER (2013)

Review Chemistry, Medicinal

Fucoxanthin: A Marine Carotenoid Exerting Anti-Cancer Effects by Affecting Multiple Mechanisms

Sangeetha Ravi Kumar et al.

MARINE DRUGS (2013)

Review Oncology

Crossing the endothelial barrier during metastasis

Nicolas Reymond et al.

NATURE REVIEWS CANCER (2013)

Article Cell Biology

Cdc42 promotes transendothelial migration of cancer cells through β1 integrin

Nicolas Reymond et al.

JOURNAL OF CELL BIOLOGY (2012)

Review Biochemistry & Molecular Biology

Epithelial-Mesenchymal Transitions in Development and Disease

Jean Paul Thiery et al.

Article Biochemistry & Molecular Biology

The epithelial-mesenchymal transition generates cells with properties of stem cells

Sendurai A. Mani et al.

Review Biochemistry & Molecular Biology

Shared principles in NF-κB signaling

Matthew S. Hayden et al.

Article Biochemistry & Molecular Biology

Structural basis for the autoinhibition of focal adhesion kinase

Daniel Lietha et al.

Review Cell Biology

Complex networks orchestrate epithelial-mesenchymal transitions

JP Thiery et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2006)

Article Oncology

Circulating tumor cells in patients with breast cancer dormancy

SD Meng et al.

CLINICAL CANCER RESEARCH (2004)