Overcoming the blood-brain barrier for the therapy of malignant brain tumor: current status and prospects of drug delivery approaches

Article Chemistry, Multidisciplinary

Liposome delivery to the brain with rapid short-pulses of focused ultrasound and microbubbles

Sophie Morse et al.

Summary: The study investigates a noninvasive method of using ultrasound pulses to deliver liposomes across the blood-brain barrier for efficient drug delivery to the brain.

JOURNAL OF CONTROLLED RELEASE (2022)

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Review Engineering, Biomedical

Intranasal Delivery of Functionalized Polymeric Nanomaterials to the Brain

Shuai Zha et al.

Summary: Intranasal delivery of nanoparticles offers a non-invasive and effective method for delivering therapeutic agents to the brain, bypassing the blood-brain barrier.

ADVANCED HEALTHCARE MATERIALS (2022)

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Article Polymer Science

Polymeric Composite of Magnetite Iron Oxide Nanoparticles and Their Application in Biomedicine: A Review

Moises Bustamante-Torres et al.

Summary: In recent years, a wide range of nanomaterials, including magnetic nanoparticles, have been extensively studied for various purposes. Iron oxide nanoparticles and superparamagnetic iron oxide nanoparticles have attracted significant attention due to their physicochemical and magnetic properties, as well as their compatibility with organic or inorganic compounds. The incorporation of these nanoparticles into hydrogels has garnered interest in the field of biomedicine. This review discusses various synthesis methods for magnetite nanoparticles and introduces different processing techniques for magnetite-based nanocomposites in hydrogels. The characterization techniques commonly used to study magnetic nanoparticles and magnetic gels are also discussed.

POLYMERS (2022)

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Article Materials Science, Biomaterials

Blood-brain barrier penetrating liposomes with synergistic chemotherapy for glioblastoma treatment

Ying Zhang et al.

Summary: A glucose-functionalized liposome was developed to co-load temozolomide and pro-apoptotic peptide for the treatment of aggressive and malignant glioblastoma, showing significant anti-tumor efficacy and promising potential for future anti-GBM formulations.

BIOMATERIALS SCIENCE (2022)

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Review Chemistry, Physical

Integrated therapy platform of exosomal system: hybrid inorganic/organic nanoparticles with exosomes for cancer treatment

Ming-Hsien Chan et al.

Summary: This review article focuses on the potential of using biomimetic nanoparticles derived from exosomes as drug carriers in cancer therapy, highlighting their targeting capabilities and biocompatibility. Challenges in exosome research include inefficient separation methods, difficulties in characterization/tracking, and a lack of specific biomarkers.

NANOSCALE HORIZONS (2022)

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Review Biochemistry & Molecular Biology

Crossing the Blood-Brain Barrier: Advances in Nanoparticle Technology for Drug Delivery in Neuro-Oncology

Andrew M. Hersh et al.

Summary: This article provides a review of the potential of nanoparticles (NPs) in improving drug delivery to brain tumors. The unique physical and chemical properties of NPs and the mechanisms of NP transport across the blood-brain barrier are discussed, along with the major types of NPs investigated for brain tumor treatment. In addition, the use of NPs as imaging contrast agents and their conjugation with imaging probes for visualization and treatment monitoring are explored. Finally, the limitations of NPs for brain tumor treatment are discussed.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

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Article Chemistry, Multidisciplinary

Blood-brain barrier crossing using magnetic stimulated nanoparticles

Jingfan Chen et al.

Summary: Due to the low permeability and high selectivity of the blood-brain barrier, traditional drug delivery to the brain is limited. Magnetic nanoparticles have shown potential for efficient blood-brain barrier crossing under a static magnetic field. In this study, a physiologically based pharmacokinetic model was developed to simulate the in vivo dynamics of superparamagnetic iron oxide nanoparticles in mice. The model was validated through in vivo experiments and showed good agreement with the results. This study is important for future research on non-invasive targeted drug delivery to the brain.

JOURNAL OF CONTROLLED RELEASE (2022)

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Article Pharmacology & Pharmacy

Hyaluronic acid conjugated albumin nanoparticles for efficient receptor mediated brain targeted delivery of temozolomide

Ritu R. Kudarha et al.

Summary: The study demonstrated that the HA-TNPs have potential for targeted delivery to brain tumors with improved cellular uptake and enhanced antitumor activity compared to pure TMZ.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2021)

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Review Pharmacology & Pharmacy

Targeting the blood-brain barrier for the delivery of stroke therapies

Anisha D'Souza et al.

Summary: This study discusses the viable strategy of targeting endothelial cells for drug delivery to facilitate neuroprotective effects, using BDNF as an example. It emphasizes the advances in cell-derived EVs for CNS targeting and drug delivery, as well as the potential of engineered EVs as an effective strategy to deliver drugs to the ischemic brain.

ADVANCED DRUG DELIVERY REVIEWS (2021)

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Article Biochemistry & Molecular Biology

Angiopep-2 modi fi ed lipid-coated mesoporous silica nanoparticles for glioma targeting therapy overcoming BBB

Jingjing Zhu et al.

Summary: This study developed a novel nanomedicine for treating glioma, which achieved better drug targeting effect and showed significant improvement in treatment efficacy and survival time in animal experiments.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2021)

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Article Biochemistry & Molecular Biology

Biotin and glucose co-modified multi-targeting liposomes for efficient delivery of chemotherapeutics for the treatment of glioma

Qijun Liu et al.

Summary: In this study, multi-targeting liposomes based on glucose and biotin were constructed for the first time, showing promising efficacy in targeting glioma. The results indicated that the multi-targeting liposomes had satisfactory glioma-targeting ability in vitro and could be a potential formulation for glioma treatment, consistent with the in vivo imaging results.

BIOORGANIC & MEDICINAL CHEMISTRY (2021)

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Review Pharmacology & Pharmacy

Liposomal doxorubicin as targeted delivery platform: Current trends in surface functionalization

Vivek Makwana et al.

Summary: Liposomal delivery systems have greatly improved the efficacy and safety of chemotherapeutic agents, particularly in the case of doxorubicin. Surface modification of liposomes, such as pegylation, can prolong drug circulation time and enhance drug accumulation in tumor tissue through passive targeting. Active targeting using biological ligands on the liposome surface shows potential for further improving tumor targeting efficiency in drug delivery systems.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2021)

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Article Chemistry, Multidisciplinary

Multifunctionalized Gold Sub-Nanometer Particles for Sensitizing Radiotherapy against Glioblastoma

Cheng-Yuan Dong et al.

Summary: The study demonstrates the potential advantages of the integrated pharmaceutics D-iGSNPs in treating glioblastoma, enhancing sensitivity to radiotherapy and achieving almost the same therapeutic effect as high-dose radiotherapy.

SMALL (2021)

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Review Biotechnology & Applied Microbiology

Virus-like particles: preparation, immunogenicity and their roles as nanovaccines and drug nanocarriers

Saghi Nooraei et al.

Summary: Virus-like particles (VLPs) are virus-derived structures without genetic material, able to self-assemble and mimic viruses, utilized in candidate vaccines and successful applications in targeted drug delivery and gene therapy. Modifying the surface of VLPs for increased specificity and longevity in specific cells or tissues may enhance their future use.

JOURNAL OF NANOBIOTECHNOLOGY (2021)

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Article Chemistry, Multidisciplinary

Exosome-Coated 10B Carbon Dots for Precise Boron Neutron Capture Therapy in a Mouse Model of Glioma In Situ

Juan Li et al.

Summary: Novel boron-containing carbon dots (BCDs) were designed and prepared for boron neutron capture therapy (BNCT), encapsulated in exosomes (Exos) from macrophages to form BCD-Exos, achieving excellent therapeutic effects on brain glioma in mice models with 100% survival rate. Adjusted biodistribution of boron, enhanced T/N ratios, and precise match between boron and neutron exposure at the tumor site in vivo with fluorescence imaging of BCD-Exos contributed to the success of the treatment.

ADVANCED FUNCTIONAL MATERIALS (2021)

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Article Chemistry, Multidisciplinary

Influence of Coating and Size of Magnetic Nanoparticles on Cellular Uptake for In Vitro MRI

Belen Cortes-Llanos et al.

Summary: Research on IONPs with different coatings and core sizes has provided insights for their application as negative contrast agents in clinical settings. The study found that specific core size and coating combinations yield the best results for MRI contrast enhancement.

NANOMATERIALS (2021)

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Review Infectious Diseases

Nanomaterials as drug delivery systems with antibacterial properties: current trends and future priorities

Khatereh Khorsandi et al.

Summary: This review highlights the mechanisms of action of nanoparticles in killing bacteria and their potential in overcoming multidrug-resistant bacteria. It discusses the characteristics and applications of organic and inorganic nanoparticles, emphasizing the role of nanotechnology in enhancing drug absorption, targeted drug delivery, and reducing side effects.

EXPERT REVIEW OF ANTI-INFECTIVE THERAPY (2021)

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Editorial Material Nanoscience & Nanotechnology

Clinical translation of silica nanoparticles

Taskeen Iqbal Janjua et al.

Summary: Silica nanoparticles have shown promising safety, efficacy, and viability in clinical trials for various biomedical applications such as oral drug delivery, diagnostics, and therapy, indicating their potential in the field.

NATURE REVIEWS MATERIALS (2021)

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Review Nanoscience & Nanotechnology

The Influence of Size and Chemical Composition of Silver and Gold Nanoparticles on in vivo Toxicity with Potential Applications to Central Nervous System Diseases

Daniela F. Baez et al.

Summary: This review summarizes the in vivo studies on the diagnosis and treatment of brain diseases using SNPs and GNPs from the past ten years, with a focus on addressing toxicity as a crucial topic. The research highlights the impact of nanoparticle size and chemical composition on in vivo toxicity.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2021)

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Review Pharmacology & Pharmacy

Design of liposomes as drug delivery system for therapeutic applications

Diana Guimaraes et al.

Summary: Liposomes are effective drug delivery systems that improve therapeutic efficacy, being nontoxic and biodegradable. Key aspects such as design, production techniques, drug loading, and characterization for in vitro and in vivo performance are essential for successful liposomal formulations. Other topics explored include functionalization, targeting strategies, stability, limitations, and current market applications of liposomes in various therapeutic fields.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2021)

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Review Pharmacology & Pharmacy

Blood-Brain Barrier Dysfunction in CNS Disorders and Putative Therapeutic Targets: An Overview

Sabrina Rahman Archie et al.

Summary: The blood-brain barrier is a crucial component of the central nervous system, maintaining brain homeostasis by controlling passage of substances. Regulated by a multicellular system, including endothelial cells, astrocytes, pericytes, and neurons, the BBB plays a role in the onset and progression of various neurological disorders.

PHARMACEUTICS (2021)

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Article Biotechnology & Applied Microbiology

RGD Peptide-Conjugated Selenium Nanocomposite Inhibits Human Glioma Growth by Triggering Mitochondrial Dysfunction and ROS-Dependent MAPKs Activation

Wenjian Liu et al.

Summary: The study demonstrated that Ag@Se@RGD NPs had stable particle size and morphology in physiological conditions and induced significant integrin-targeted intracellular uptake. In vitro experiments showed that Ag@Se@RGD NPs dose-dependently inhibited U251 human glioma cell growth by inducing cell apoptosis through triggering mitochondrial dysfunction and ROS-dependent MAPKs activation. In vivo administration of Ag@Se@RGD NPs effectively inhibited U251 tumor xenograft growth by inducing apoptosis through regulation of MAPKs activation.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2021)

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Review Oncology

Breaching the Blood-Brain Tumor Barrier for Tumor Therapy

Fabrizio Marcucci et al.

Summary: The blood-brain tumor barrier (BBTB) is a major obstacle for delivering anticancer drugs to central nervous system tumors. Recent advances in various conjugates and drug delivery technologies have shown promising results in breaching the BBTB and increasing drug delivery to brain tumors, without significant adverse events.

CANCERS (2021)

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Article Robotics

Dual-responsive biohybrid neutrobots for active target delivery

Hongyue Zhang et al.

Summary: Neutrophil-based microrobots, constructed by phagocytosis of drug-loaded magnetic nanogels enveloped in Escherichia coli membrane, exhibit controllable intravascular movement and can autonomously aggregate in the brain by positive chemotactic motion along the gradient of inflammatory factors. These dual-responsive neutrobots show promise for targeted drug delivery to inhibit tumor cell proliferation compared to traditional drug injection, leveraging the biological characteristics of natural neutrophils that artificial microrobots cannot replicate.

SCIENCE ROBOTICS (2021)

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Review Biology

In Vitro Assembly of Virus-Like Particles and Their Applications

Dinh To Le et al.

Summary: Virus-like particles (VLPs) are increasingly being used in vaccine development and drug delivery. Assembly of VLPs from purified monomers in a chemically defined reaction has advantages over in vivo assembly, as it avoids encapsulating host-derived components. The uses of in vitro produced VLPs as vaccines and for therapeutic delivery are also reported.

LIFE-BASEL (2021)

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Article Engineering, Biomedical

Inflammatory tumor microenvironment responsive neutrophil exosomes-based drug delivery system for targeted glioma therapy

Jun Wang et al.

Summary: NEs-Exos system exhibits neutrophil-like chemotactic function and BBB penetration capability, efficiently suppressing tumor growth and prolonging survival time in a glioma mouse model.

BIOMATERIALS (2021)

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Article Pharmacology & Pharmacy

From blood to brain: blood cell-based biomimetic drug delivery systems

Yong-Jiang Li et al.

Summary: Biomimetic drug delivery systems based on blood cells for brain drug delivery have rapidly grown, showcasing their engineering feasibility and versatile delivery ability, but face translational challenges in the future.

DRUG DELIVERY (2021)

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Review Nanoscience & Nanotechnology

Carbon Dots: A Future Blood-Brain Barrier Penetrating Nanomedicine and Drug Nanocarrier

Wei Zhang et al.

Summary: Nanoparticles, especially carbon dots, show unprecedented potential for drug delivery across the blood-brain barrier, offering hope for treating central nervous system diseases. With abundant functional groups on their surface, they can conjugate with diverse drugs to form versatile drug nanocarriers.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2021)

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Review Chemistry, Multidisciplinary

Biomimetic and cell-based nanocarriers-New strategies for brain tumor targeting

D. Mendanha et al.

Summary: In the last two decades, significant advances in the treatment of the most common and malignant types of brain tumors have not been achieved, primarily due to difficulties in drug delivery to the central nervous system and associated severe side effects. Research on cell-based nanocarriers is exploring the potential for crossing biological barriers and targeting brain tumors with higher selectivity, offering new hope for safe and effective treatments.

JOURNAL OF CONTROLLED RELEASE (2021)

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Review Medicine, Research & Experimental

Targeting receptor-ligand chemistry for drug delivery across blood-brain barrier in brain diseases

Danielle Paige Anthony et al.

Summary: The blood-brain barrier is a complex structure composed of endothelial cells with tight junctions and regulated by various cells like astrocytes and neurons. While traditional drug delivery methods pose challenges for treating brain diseases, receptor-mediated drug delivery is considered an efficient and safe strategy that exploits the internalization of ligands by specific receptors on the blood-brain barrier.

LIFE SCIENCES (2021)

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Article Chemistry, Multidisciplinary

Virus-inspired nanosystems for drug delivery

Zhihuan Liao et al.

Summary: Viruses have evolved over millions of years to efficiently infect cells using their unique structures, inspiring the design of drug delivery processes to maximize therapeutic effects. Nanocarriers must navigate through the immune system, barriers, and cells to release drugs. Virus-like nanosystems have been designed for drug delivery, emphasizing their novel design principles.

NANOSCALE (2021)

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Article Materials Science, Multidisciplinary

Targeted Photoacoustic Imaging of Brain Tumor Mediated by Neutrophils Engineered with Lipid-Based Molecular Probe

Xingang Liu et al.

Summary: The study developed a lipid-decorated molecular photoacoustic contrast agent TFML, which effectively labeled live neutrophils for targeted brain tumor imaging in mice glioblastoma multiforme detection. This approach presents a promising prospect for neutrophil-based nanotherapeutics research.

ACS MATERIALS LETTERS (2021)

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Article Multidisciplinary Sciences

Incidence, mortality and survival in multiple myeloma compared to other hematopoietic neoplasms in Sweden up to year 2016

Kari Hemminki et al.

Summary: Survival in multiple myeloma (MM) has shown favorable development in the past few decades, with the improvement mainly concentrated in the first year rather than the fifth year when compared to other hematopoietic neoplasms. The linear increase in 5-year survival for female patients may be attributed to multiple small improvements in the first year of care.

SCIENTIFIC REPORTS (2021)

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Review Materials Science, Biomaterials

Near infrared photothermal conversion materials: mechanism, preparation, and photothermal cancer therapy applications

Jie Li et al.

Summary: This review summarizes the application of photothermal materials in cancer therapy, including inorganic materials, organic materials, and organic-inorganic composite materials. The final therapeutic effect of photothermal therapy depends on the photothermal conversion efficiency, biocompatibility, and photothermal stability of the materials. The perspectives and obstacles in the further development of photothermal materials are overviewed.

JOURNAL OF MATERIALS CHEMISTRY B (2021)

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Article Oncology

Long-term relative survival from melanoma in Germany 1997-2013

Alicia Brunssen et al.

MELANOMA RESEARCH (2020)

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Review Biotechnology & Applied Microbiology

Viral vector: potential therapeutic for glioblastoma multiforme

Ceera Manikandan et al.

CANCER GENE THERAPY (2020)

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Article Oncology

Ultrasmall Core-Shell Silica Nanoparticles for Precision Drug Delivery in a High-Grade Malignant Brain Tumor Model

Rupa Juthani et al.

CLINICAL CANCER RESEARCH (2020)

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Review Nanoscience & Nanotechnology

Virus-like particles for vaccination against cancer

Mona O. Mohsen et al.

WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY (2020)

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Article Chemistry, Physical

Multifaceted applications of green carbon dots synthesized from renewable sources

Neeraj Tejwan et al.

ADVANCES IN COLLOID AND INTERFACE SCIENCE (2020)

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Article Oncology

Localized Metabolomic Gradients in Patient-Derived Xenograft Models of Glioblastoma

Elizabeth C. Randall et al.

CANCER RESEARCH (2020)

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Review Pharmacology & Pharmacy

Nose-to-brain delivery of antiglioblastoma drugs embedded into lipid nanocarrier systems: status quo and outlook

Fakhara Sabir et al.

DRUG DISCOVERY TODAY (2020)

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Review Instruments & Instrumentation

Delivery across the blood-brain barrier: nanomedicine for glioblastoma multiforme

Lynn Jena et al.

DRUG DELIVERY AND TRANSLATIONAL RESEARCH (2020)

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Article Nanoscience & Nanotechnology

Protein-Carbon Dot Nanohybrid-Based Early Blood-Brain Barrier Damage Theranostics

Yuefang Niu et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

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Review Pharmacology & Pharmacy

Intrathecal drug delivery in the era of nanomedicine

M. J. Fowler et al.

ADVANCED DRUG DELIVERY REVIEWS (2020)

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Review Engineering, Biomedical

Microphysiological systems for recapitulating physiology and function of blood-brain barrier

Suyeong Seo et al.

BIOMATERIALS (2020)

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Article Oncology

Local Intracerebral Immunomodulation Using Interleukin-Expressing Mesenchymal Stem Cells in Glioblastoma

Malte Mohme et al.

CLINICAL CANCER RESEARCH (2020)

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Article Pharmacology & Pharmacy

Combination of Paclitaxel and R-flurbiprofen loaded PLGA nanoparticles suppresses glioblastoma growth on systemic administration

Secil Caban-Toktas et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2020)

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Review Biochemistry & Molecular Biology

SLC22A5 (OCTN2) Carnitine Transporter-Indispensable for Cell Metabolism, a Jekyll and Hyde of Human Cancer

Barbara Juraszek et al.

MOLECULES (2020)

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Article Neurosciences

Selenium nanoparticles reduce glucose metabolism and promote apoptosis of glioma cells through reactive oxygen species-dependent manner

Binchu Xu et al.

NEUROREPORT (2020)

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Article Engineering, Environmental

Mesenchymal stem cells transporting black phosphorus-based biocompatible nanospheres: Active trojan horse for enhanced photothermal cancer therapy

Miaomiao Luo et al.

CHEMICAL ENGINEERING JOURNAL (2020)

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Article Biochemistry & Molecular Biology

Locoregional delivery of CAR T cells to the cerebrospinal fluid for treatment of metastatic medulloblastoma and ependymoma

Laura K. Donovan et al.

NATURE MEDICINE (2020)

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Review Chemistry, Multidisciplinary

Silica-Based Nanoparticles for Biomedical Applications: From Nanocarriers to Biomodulators

Yannan Yang et al.

ACCOUNTS OF CHEMICAL RESEARCH (2020)

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Review Neurosciences

Revisiting the blood-brain barrier: A hard nut to crack in the transportation of drug molecules

Seetha Harilal et al.

BRAIN RESEARCH BULLETIN (2020)

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Article Pharmacology & Pharmacy

Intranasal Delivery of Targeted Nanoparticles Loaded With miR-132 to Brain for the Treatment of Neurodegenerative Diseases

Yu Su et al.

FRONTIERS IN PHARMACOLOGY (2020)

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Review Chemistry, Multidisciplinary

Surface Modification of Iron Oxide-Based Magnetic Nanoparticles for Cerebral Theranostics: Application and Prospection

Yanyue Wu et al.

NANOMATERIALS (2020)

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Article Nanoscience & Nanotechnology

ICG-Loaded PEGylated BSA-Silver Nanoparticles for Effective Photothermal Cancer Therapy

Taehoon Park et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2020)

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Review Cell Biology

Endocytosis: A Turnover Mechanism Controlling Ion Channel Function

Irene Estadella et al.

CELLS (2020)

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Article Biotechnology & Applied Microbiology

Nanoparticle-based co-delivery of siRNA and paclitaxel for dual-targeting of glioblastoma

Jun Yang et al.

NANOMEDICINE (2020)

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Article Biotechnology & Applied Microbiology

Trojan horse monocyte-mediated delivery of conjugated polymer nanoparticles for improved photodynamic therapy of glioblastoma

Luis E. Ibarra et al.

NANOMEDICINE (2020)

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Review Pharmacology & Pharmacy

Gold Nanoparticles in Glioma Theranostics

Mohammad Norouzi

PHARMACOLOGICAL RESEARCH (2020)

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Article Medicine, Research & Experimental

Paclitaxel/methotrexate co-loaded PLGA nanoparticles in glioblastoma treatment: Formulation development and in vitro antitumor activity evaluation

Fatemeh Madani et al.

LIFE SCIENCES (2020)

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Article Oncology

Dual-Target Peptide-Modified Erythrocyte Membrane-Enveloped PLGA Nanoparticles for the Treatment of Glioma

Yuexin Cui et al.

FRONTIERS IN ONCOLOGY (2020)

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Article Oncology

Local intracerebral inhibition of IRE1 by MKC8866 sensitizes glioblastoma to irradiation/chemotherapy in vivo

Pierre Jean Le Reste et al.

CANCER LETTERS (2020)

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Article Oncology

Head and neck cutaneous melanoma: 5-year survival analysis in a Serbian university center

Aleksandar Visnjic et al.

WORLD JOURNAL OF SURGICAL ONCOLOGY (2020)

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Review Neurosciences

A blood-brain barrier overview on structure, function, impairment, and biomarkers of integrity

Hossam Kadry et al.

FLUIDS AND BARRIERS OF THE CNS (2020)

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Article Multidisciplinary Sciences

Systemic brain tumor delivery of synthetic protein nanoparticles for glioblastoma therapy

Jason V. Gregory et al.

NATURE COMMUNICATIONS (2020)

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Review Pharmacology & Pharmacy

Large-Scale Production of Lentiviral Vectors: Current Perspectives and Challenges

Eduardo Martinez-Molina et al.

PHARMACEUTICS (2020)

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Review Engineering, Biomedical

Overcoming the delivery problem for therapeutic genome editing: Current status and perspective of non-viral methods

Tatiana Mashel et al.

BIOMATERIALS (2020)

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Review Medicine, Research & Experimental

Nanocarrier-based drug combination therapy for glioblastoma

Mengnan Zhao et al.

THERANOSTICS (2020)

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Article Materials Science, Biomaterials

Biomimetic drug delivery platforms based on mesenchymal stem cells impregnated with light-responsive submicron sized carriers

Albert R. Muslimov et al.

BIOMATERIALS SCIENCE (2020)

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Review Nanoscience & Nanotechnology

Optically responsive delivery platforms: from the design considerations to biomedical applications

Irina Koryakina et al.

NANOPHOTONICS (2020)

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Review Medicine, Research & Experimental

Silver nanoparticles: Synthesis, medical applications and biosafety

Li Xu et al.

THERANOSTICS (2020)

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Review Oncology

Targeting the Warburg effect for cancer treatment: Ketogenic diets for Check for management of glioma

Angela Poff et al.

SEMINARS IN CANCER BIOLOGY (2019)

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Article Nanoscience & Nanotechnology

L-DOPA functionalized, multi-branched gold nanoparticles as brain-targeted nano-vehicles

Daniel A. Gonzalez-Carter et al.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2019)

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Article Chemistry, Multidisciplinary

Chemotherapy sensitization of glioblastoma by focused ultrasound-mediated delivery of therapeutic liposomes

Alexandros Papachristodoulou et al.

JOURNAL OF CONTROLLED RELEASE (2019)

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Article Neurosciences

Human Brain/Cloud Interface

Nuno R. B. Martins et al.

FRONTIERS IN NEUROSCIENCE (2019)

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Article Chemistry, Multidisciplinary

Ligand-Modified Cell Membrane Enables the Targeted Delivery of Drug Nanocrystals to Glioma

Zhilan Chai et al.

ACS NANO (2019)

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Article Engineering, Biomedical

Brain and bone cancer targeting by a ferrofluid composed of superparamagnetic iron-oxide/silica/carbon nanoparticles (earthicles)

Victoria M. Wu et al.

ACTA BIOMATERIALIA (2019)

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Article Engineering, Biomedical

Nanoparticle-mediated intratumoral inhibition of miR-21 for improved survival in glioblastoma

Young-Eun Seo et al.

BIOMATERIALS (2019)

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Article Oncology

Engineered human mesenchymal stem cells for neuroblastoma therapeutics

Valentina Nieddu et al.

ONCOLOGY REPORTS (2019)

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Review Immunology

CAR T cells for brain tumors: Lessons learned and road ahead

David Akhavan et al.

IMMUNOLOGICAL REVIEWS (2019)

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Review Nanoscience & Nanotechnology

Recent expansions of novel strategies towards the drug targeting into the brain

Amit Alexander et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2019)

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Review Clinical Neurology

Genetic and molecular epidemiology of adult diffuse glioma

Annette M. Molinaro et al.

NATURE REVIEWS NEUROLOGY (2019)

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Article Chemistry, Multidisciplinary

Far-Red to Near-Infrared Carbon Dots: Preparation and Applications in Biotechnology

Xinxin Shi et al.

SMALL (2019)

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Review Nanoscience & Nanotechnology

Nanovaccines for cancer immunotherapy

Yu Zhang et al.

WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY (2019)

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Article Materials Science, Multidisciplinary

Menthol-modified BSA nanoparticles for glioma targeting therapy using an energy restriction strategy

Jianming Liang et al.

NPG ASIA MATERIALS (2019)

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Review Clinical Neurology

Dysembryoplastic Neuroepithelial Tumors: What You Need to Know

Sabino Luzzi et al.

WORLD NEUROSURGERY (2019)

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Review Oncology

Optimizing Neuro-Oncology Imaging: A Review of Deep Learning Approaches for Glioma Imaging

Madeleine M. Shaver et al.

CANCERS (2019)

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Article Chemistry, Multidisciplinary

Dual functionalized liposomes for efficient co-delivery of anti-cancer chemotherapeutics for the treatment of glioblastoma

Sushant Lakkadwala et al.

JOURNAL OF CONTROLLED RELEASE (2019)

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Article Biochemistry & Molecular Biology

Cell-Penetrating Peptide and Transferrin Co-Modified Liposomes for Targeted Therapy of Glioma

Xi Wang et al.

MOLECULES (2019)

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Article Multidisciplinary Sciences

Accessing neuroinflammation sites: Monocyte/neutrophil-mediated drug delivery for cerebral ischemia

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Review Pharmacology & Pharmacy

A Role for Nanoparticles in Treating Traumatic Brain Injury

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PHARMACEUTICS (2019)

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Confining Iron Oxide Nanocubes inside Submicrometric Cavities as a Key Strategy To Preserve Magnetic Heat Losses in an Intracellular Environment

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ACS APPLIED MATERIALS & INTERFACES (2019)

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Article Nanoscience & Nanotechnology

Blood-Brain Barrier- and Blood-Brain Tumor Barrier-Penetrating Peptide-Derived Targeted Therapeutics for Glioma and Malignant Tumor Brain Metastases

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ACS APPLIED MATERIALS & INTERFACES (2019)

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Article Pharmacology & Pharmacy

Development of dual drug loaded PLGA based mesoporous silica nanoparticles and their conjugation with Angiopep-2 to treat glioma

Geetha B. Heggannavar et al.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2019)

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CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2012-2016

Quinn T. Ostrom et al.

NEURO-ONCOLOGY (2019)

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Article Multidisciplinary Sciences

Blood-brain barrier permeable nano immunoconjugates induce local immune responses for glioma therapy

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NATURE COMMUNICATIONS (2019)

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Article Nanoscience & Nanotechnology

Dual-Modified Novel Biomimetic Nanocarriers Improve Targeting and Therapeutic Efficacy in Glioma

Shiyao Fu et al.

ACS APPLIED MATERIALS & INTERFACES (2019)

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Article Chemistry, Medicinal

Liposomes actively recognizing the glucose transporter GLUT1 and integrin αvβ3 for dual-targeting of glioma

Qiuyi Fu et al.

ARCHIV DER PHARMAZIE (2019)

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Article Biochemical Research Methods

Carbon Nitride Dots: A Selective Bioimaging Nanomaterial

Piumi Y. Liyanage et al.

BIOCONJUGATE CHEMISTRY (2019)

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Review Engineering, Biomedical

Nanomaterial-based blood-brain-barrier (BBB) crossing strategies

Jinbing Xie et al.

BIOMATERIALS (2019)

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18F-DOPA PET/CT in brain tumors: impact on multidisciplinary brain tumor board decisions

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EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2019)

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Article Chemistry, Medicinal

Development of Nanoparticles for Drug Delivery to Brain Tumor: The Effect of Surface Materials on Penetration Into Brain Tissue

Chenlu Lei et al.

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Article Nanoscience & Nanotechnology

Safe and Effective Delivery of Antitumor Drug Using Mesenchymal Stem Cells Impregnated with Submicron Carriers

Alexander S. Timin et al.

ACS APPLIED MATERIALS & INTERFACES (2019)

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Neurosurgical treatment and outcome patterns of meningioma in Sweden: a nationwide registry-based study

Alba Corell et al.

ACTA NEUROCHIRURGICA (2019)

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Article Chemistry, Multidisciplinary

Systemic Delivery of Monoclonal Antibodies to the Central Nervous System for Brain Tumor Therapy

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ADVANCED MATERIALS (2019)

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Convection-Enhanced Delivery of a Virus-Like Nanotherapeutic Agent with Dual-Modal Imaging for Besiegement and Eradication of Brain Tumors

Hao-Han Pang et al.

THERANOSTICS (2019)

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Delivery of drugs into brain tumors using multicomponent silica nanoparticles

O. Turan et al.

NANOSCALE (2019)

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I6P7 peptide modified superparamagnetic iron oxide nanoparticles for magnetic resonance imaging detection of low-grade brain gliomas

Junyi Tan et al.

JOURNAL OF MATERIALS CHEMISTRY B (2019)

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Article Chemistry, Multidisciplinary

Triple conjugated carbon dots as a nano-drug delivery model for glioblastoma brain tumors

Sajini D. Hettiarachchi et al.

NANOSCALE (2019)

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Review Pharmacology & Pharmacy

Overcoming the Blood-Brain Barrier. Challenges and Tricks for CNS Drug Delivery

Luca Anna Bors et al.

SCIENTIA PHARMACEUTICA (2019)

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Review Oncology

Organic Nanoparticles as Drug Delivery Systems and Their Potential Role in the Treatment of Chronic Myeloid Leukemia

Mohammed Hussein Kamareddine et al.

TECHNOLOGY IN CANCER RESEARCH & TREATMENT (2019)

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Review Oncology

Nanomedicine review: clinical developments in liposomal applications

Esteban Beltran-Gracia et al.

CANCER NANOTECHNOLOGY (2019)

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Review Chemistry, Multidisciplinary

Recent development of carbon quantum dots regarding their optical properties, photoluminescence mechanism, and core structure

Keenan J. Mintz et al.

NANOSCALE (2019)

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Review Pharmacology & Pharmacy

A comprehensive review in improving delivery of small-molecule chemotherapeutic agents overcoming the blood-brain/brain tumor barriers for glioblastoma treatment

Da Wang et al.

DRUG DELIVERY (2019)

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Review Pharmacology & Pharmacy

Emerging therapeutic targets in myeloproliferative neoplasms and peripheral T-cell leukemia and lymphomas

Anna Orlova et al.

EXPERT OPINION ON THERAPEUTIC TARGETS (2018)

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Review Biochemistry & Molecular Biology

Dopamine and Levodopa Prodrugs for the Treatment of Parkinson's Disease

Fatma Haddad et al.

MOLECULES (2018)

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Review Nanoscience & Nanotechnology

Nanotherapeutic systems for local treatment of brain tumors

Rami Walid Chakroun et al.

WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY (2018)

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Article Engineering, Biomedical

Cell-Based Drug Delivery and Use of Nano- and Microcarriers for Cell Functionalization

Alexander S. Timin et al.

ADVANCED HEALTHCARE MATERIALS (2018)

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Article Biotechnology & Applied Microbiology

L-Carnitine-conjugated nanoparticles to promote permeation across blood-brain barrier and to target glioma cells for drug delivery via the novel organic cation/carnitine transporter OCTN2

Longfa Kou et al.

ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY (2018)

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Article Oncology

Differences in Breast Cancer Survival by Molecular Subtypes in the United States

Nadia Howlader et al.

CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2018)

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Review Clinical Neurology

Current treatment options for meningioma

Caroline Apra et al.

EXPERT REVIEW OF NEUROTHERAPEUTICS (2018)

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Transferrin-targeted, resveratrol-loaded liposomes for the treatment of glioblastoma

Aditi Jhaveri et al.

JOURNAL OF CONTROLLED RELEASE (2018)

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Review Medicine, Research & Experimental

Mechanism of intranasal drug delivery directly to the brain

Tyler P. Crowe et al.

LIFE SCIENCES (2018)

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Exploring the optimal ratio of D-glucose/L-aspartic acid for targeting carbon dots toward brain tumor cells

Lihong Qiao et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2018)

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Article Biotechnology & Applied Microbiology

Optimization of IL13Rα2-Targeted Chimeric Antigen Receptor T Cells for Improved Anti-tumor Efficacy against Glioblastoma

Christine E. Brown et al.

MOLECULAR THERAPY (2018)

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Review Biochemistry & Molecular Biology

Strategies for Enhancing the Permeation of CNS-Active Drugs through the Blood-Brain Barrier: A Review

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MOLECULES (2018)

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Article Nanoscience & Nanotechnology

Enhancing glioblastoma treatment using cisplatin-gold-nanoparticle conjugates and targeted delivery with magnetic resonance-guided focused ultrasound

Daniel Coluccia et al.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2018)

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Review Oncology

Current state of immunotherapy for glioblastoma

Michael Lim et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2018)

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Review Cell Biology

Mechanisms of clathrin-mediated endocytosis

Marko Kaksonen et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2018)

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Article Chemistry, Multidisciplinary

Tailored surface silica nanoparticles for blood-brain barrier penetration: Preparation and in vivo investigation

B. I. Tamba et al.

ARABIAN JOURNAL OF CHEMISTRY (2018)

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Review Medicine, Research & Experimental

Current Strategies for Brain Drug Delivery

Xiaowei Dong

THERANOSTICS (2018)

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Review Medicine, Research & Experimental

Applications of gold nanoparticles in virus detection

Mohamed Shehata Draz et al.

THERANOSTICS (2018)

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Review Clinical Neurology

Current treatment options for meningioma

Caroline Apra et al.

EXPERT REVIEW OF NEUROTHERAPEUTICS (2018)

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Overcoming blood-brain barrier by HER2-targeted nanosystem to suppress glioblastoma cell migration, invasion and tumor growth

Zhenhuan Song et al.

JOURNAL OF MATERIALS CHEMISTRY B (2018)

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Review Cell & Tissue Engineering

Cancer Stem Cells (CSCs) in Drug Resistance and their Therapeutic Implications in Cancer Treatment

Lan Thi Hanh Phi et al.

STEM CELLS INTERNATIONAL (2018)

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Review Clinical Neurology

Gold Nanoparticles for Brain tumor imaging: a Systematic Review

Antonio Meola et al.

FRONTIERS IN NEUROLOGY (2018)

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Article Clinical Neurology

Bupivacaine in alginate and chitosan nanoparticles: an in vivo evaluation of efficacy, pharmacokinetics, and local toxicity

Cintia Maria Saia Cereda et al.

JOURNAL OF PAIN RESEARCH (2018)

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Article Oncology

Adult Glioma Incidence and Survival by Race or Ethnicity in the United States From 2000 to 2014

Quinn T. Ostrom et al.

JAMA ONCOLOGY (2018)

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Review Oncology

Beyond the Blood: Brain Barrier: The Importance of Central Nervous System (CNS) Pharmacokinetics for the Treatment of CNS Tumors, Including Diffuse Intrinsic Pontine Glioma

Katherine Elizabeth Warren

FRONTIERS IN ONCOLOGY (2018)

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Article Oncology

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

Freddie Bray et al.

CA-A CANCER JOURNAL FOR CLINICIANS (2018)

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Article Nanoscience & Nanotechnology

Magnetic targeting of paclitaxel-loaded poly(lactic-co-glycolic acid)-based nanoparticles for the treatment of glioblastoma

Lakshmi Pallavi Ganipineni et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2018)

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Article Chemistry, Multidisciplinary

Dopamine-loaded blood exosomes targeted to brain for better treatment of Parkinson's disease

Mengke Qu et al.

JOURNAL OF CONTROLLED RELEASE (2018)

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Article Microbiology

Treatment of Human Glioblastoma with a Live Attenuated Zika Virus Vaccine Candidate

Qi Chen et al.

MBIO (2018)

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Review Chemistry, Medicinal

Nanodelivery systems for overcoming limited transportation of therapeutic molecules through the blood-brain barrier

Ki-Taek Kim et al.

FUTURE MEDICINAL CHEMISTRY (2018)

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Review Medicine, General & Internal

Impact of Nanoparticles on Brain Health: An Up to Date Overview

Daniel Mihai Teleanu et al.

JOURNAL OF CLINICAL MEDICINE (2018)

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Article Pharmacology & Pharmacy

Efficient Overcoming of Blood-Brain Barrier by Functionalized Selenium Nanoparticles to Treat Glioma

Mengqi Chen et al.

ADVANCED THERAPEUTICS (2018)

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Article Pharmacology & Pharmacy

Primary M1 macrophages as multifunctional carrier combined with PLGA nanoparticle delivering anticancer drug for efficient glioma therapy

Liang Pang et al.

DRUG DELIVERY (2018)

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Article Chemistry, Analytical

Consistency of Continuous Ambulatory Interstitial Glucose Monitoring Sensors

Pei T. Wu et al.

BIOSENSORS-BASEL (2018)

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Review Neurosciences

Elimination of substances from the brain parenchyma: efflux via perivascular pathways and via the blood-brain barrier

Stephen B. Hladky et al.

FLUIDS AND BARRIERS OF THE CNS (2018)

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Article Chemistry, Multidisciplinary

Targeted delivery of paclitaxel by functionalized selenium nanoparticles for anticancer therapy through ROS-mediated signaling pathways

Guifang Gong et al.

RSC ADVANCES (2018)

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Review Pharmacology & Pharmacy

Peptides as a therapeutic avenue for nanocarrier-aided targeting of glioma

Mrunal Vitthal Wanjale et al.

EXPERT OPINION ON DRUG DELIVERY (2017)

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Review Pharmacology & Pharmacy

Advances of blood cell-based drug delivery systems

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EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2017)

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Article Engineering, Biomedical

Transferrin-conjugated magnetic dextran-spermine nanoparticles for targeted drug transport across blood-brain barrier

Maryam Ghadiri et al.

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A (2017)

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Article Oncology

Basic Facts of Breast Cancer in Korea in 2014:The 10-Year Overall Survival Progress

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JOURNAL OF BREAST CANCER (2017)

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A facile approach to functionalizing cell membrane-coated nanoparticles with neurotoxin-derived peptide for brain-targeted drug delivery

Zhilan Chai et al.

JOURNAL OF CONTROLLED RELEASE (2017)

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Review Chemistry, Multidisciplinary

Progress in brain targeting drug delivery system by nasal route

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JOURNAL OF CONTROLLED RELEASE (2017)

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Article Nanoscience & Nanotechnology

AgNPs and Ag/C225 Exert Anticancerous Effects via Cell Cycle Regulation and Cytotoxicity Enhancement

Yan Zhang et al.

JOURNAL OF NANOMATERIALS (2017)

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Review Materials Science, Biomaterials

Non-invasive approaches for drug delivery to the brain based on the receptor mediated transport

Fei Fang et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2017)

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Article Medicine, Research & Experimental

Large Amino Acid Transporter 1 Selective Liposomes of L-DOPA Functionalized Amphiphile for Combating Glioblastoma

Sukanya Bhunia et al.

MOLECULAR PHARMACEUTICS (2017)

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Article Nanoscience & Nanotechnology

Neutrophil-mediated anticancer drug delivery for suppression of postoperative malignant glioma recurrence

Jingwei Xue et al.

NATURE NANOTECHNOLOGY (2017)

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Review Oncology

Antibody-drug conjugates in glioblastoma therapy: the right drugs to the right cells

Hui K. Gan et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2017)

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Review Clinical Neurology

Intracerebroventricular Delivery as a Safe, Long-Term Route of Drug Administration

Jessica L. Cohen-Pfeffer et al.

PEDIATRIC NEUROLOGY (2017)

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Article Multidisciplinary Sciences

Magnetic forces enable controlled drug delivery by disrupting endothelial cell-cell junctions

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NATURE COMMUNICATIONS (2017)

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Article Biotechnology & Applied Microbiology

Biogenic selenium nanoparticles induce ROS-mediated necroptosis in PC-3 cancer cells through TNF activation

Praveen Sonkusre et al.

JOURNAL OF NANOBIOTECHNOLOGY (2017)

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Review Immunology

Targeting Malignant Brain Tumors with Antibodies

Rok Razpotnik et al.

FRONTIERS IN IMMUNOLOGY (2017)

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Designing nanomedicine for immuno-oncology

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NATURE BIOMEDICAL ENGINEERING (2017)

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Review Cell Biology

Metabolic Reprogramming in Glioma

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FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2017)

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Review Cell Biology

In vitro Culture of Naive Human Bone Marrow Mesenchymal Stem Cells: A Stemness Based Approach

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FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2017)

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Review Oncology

Delivery of Biologics Across the Blood-Brain Barrier with Molecular Trojan Horse Technology

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BIODRUGS (2017)

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Article Biophysics

Curcumin-loaded Poly (D, L-lactide-co-glycolide) nanovesicles induce antinociceptive effects and reduce pronociceptive cytokine and BDNF release in spinal cord after acute administration in mice

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COLLOIDS AND SURFACES B-BIOINTERFACES (2017)

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Article Nanoscience & Nanotechnology

Action of Gold Nanospikes-Based Nanoradiosensitizers: Cellular Internalization, Radiotherapy, and Autophagy

Ningning Ma et al.

ACS APPLIED MATERIALS & INTERFACES (2017)

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Review Biochemistry & Molecular Biology

Blood-brain barrier peptide shuttles

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CURRENT OPINION IN CHEMICAL BIOLOGY (2017)

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Review Oncology

Rabies virus vaccine as an immune adjuvant against cancers and glioblastoma: new studies may resurrect a neglected potential

M. A. Altinoz et al.

CLINICAL & TRANSLATIONAL ONCOLOGY (2017)

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Review Pharmacology & Pharmacy

Gold nanoparticles for applications in cancer radiotherapy: Mechanisms and recent advancements

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ADVANCED DRUG DELIVERY REVIEWS (2017)

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Brain tumor-targeted delivery and therapy by focused ultrasound introduced doxorubicin-loaded cationic liposomes

Qian Lin et al.

CANCER CHEMOTHERAPY AND PHARMACOLOGY (2016)

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Article Nanoscience & Nanotechnology

Superparamagnetic Iron Oxide Nanoparticles Modified with Tween 80 Pass through the Intact Blood-Brain Barrier in Rats under Magnetic Field

Yinping Huang et al.

ACS APPLIED MATERIALS & INTERFACES (2016)

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Article Chemistry, Multidisciplinary

Blood-Brain-Barrier-Penetrating Albumin Nanoparticles for Biomimetic Drug Delivery via Albumin-Binding Protein Pathways for Antiglioma Therapy

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ACS NANO (2016)

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Article Engineering, Biomedical

Synergistic targeting tenascin C and neuropilin-1 for specific penetration of nanoparticles for anti-glioblastoma treatment

Ting Kang et al.

BIOMATERIALS (2016)

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Review Medicine, Research & Experimental

Nanoparticles: Novel vehicles in treatment of Glioblastoma

Fatemeh Pourgholi et al.

BIOMEDICINE & PHARMACOTHERAPY (2016)

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Article Biophysics

Large amino acid transporter 1 mediated glutamate modified docetaxel-loaded liposomes for glioma targeting

Lin Li et al.

COLLOIDS AND SURFACES B-BIOINTERFACES (2016)

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Review Biochemistry & Molecular Biology

Drug-metabolizing Enzymes and Efflux Transporters in Nasal Epithelium: Influence on the Bioavailability of Intranasally Administered Drugs

Paula Oliveira et al.

CURRENT DRUG METABOLISM (2016)

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Review Clinical Neurology

Nitrosoureas in the Management of Malignant Gliomas

Alba A. Brandes et al.

CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS (2016)

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Review Pharmacology & Pharmacy

CSF, blood-brain barrier, and brain drug delivery

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EXPERT OPINION ON DRUG DELIVERY (2016)

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Plant virus nanoparticles: new applications and new benefits

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FUTURE VIROLOGY (2016)

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Article Nanoscience & Nanotechnology

Silver nanoparticles inhibit the function of hypoxia-inducible factor-1 and target genes: insight into the cytotoxicity and antiangiogenesis

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INTERNATIONAL JOURNAL OF NANOMEDICINE (2016)

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Article Nanoscience & Nanotechnology

Hydrothermal synthesis of nitrogen-doped carbon dots with real-time live-cell imaging and blood-brain barrier penetration capabilities

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INTERNATIONAL JOURNAL OF NANOMEDICINE (2016)

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Article Chemistry, Multidisciplinary

Camelid single-domain antibodies: A versatile tool for in vivo imaging of extracellular and intracellular brain targets

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JOURNAL OF CONTROLLED RELEASE (2016)

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Article Chemistry, Multidisciplinary

Biocompatibility selenium nanoparticles with an intrinsic oxidase-like activity

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JOURNAL OF NANOPARTICLE RESEARCH (2016)

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Article Oncology

Superselective intraarterial cerebral infusion of cetuximab after osmotic blood/brain barrier disruption for recurrent malignant glioma: phase I study

Shamik Chakraborty et al.

JOURNAL OF NEURO-ONCOLOGY (2016)

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Article Chemistry, Medicinal

Novel Antitransferrin Receptor Antibodies Improve the Blood-Brain Barrier Crossing Efficacy of Immunoliposomes

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JOURNAL OF PHARMACEUTICAL SCIENCES (2016)

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Review Chemistry, Multidisciplinary

Application of iron oxide nanoparticles in glioma imaging and therapy: from bench to bedside

Heng Liu et al.

NANOSCALE (2016)

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Review Oncology

Gliadel wafer implantation combined with standard radiotherapy and concurrent followed by adjuvant temozolomide for treatment of newly diagnosed high-grade glioma: a systematic literature review

Lynn S. Ashby et al.

WORLD JOURNAL OF SURGICAL ONCOLOGY (2016)

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Review Endocrinology & Metabolism

Vasoactive intestinal peptide/pituitary adenylate cyclase activating polypeptide, and their receptors and cancer

Terry W. Moody et al.

CURRENT OPINION IN ENDOCRINOLOGY DIABETES AND OBESITY (2016)

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Exploiting macrophages as targeted carrier to guide nanoparticles into glioma

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ONCOTARGET (2016)

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Review Pharmacology & Pharmacy

Near-infrared light-responsive inorganic nanomaterials for photothermal therapy

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ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES (2016)

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Article Pharmacology & Pharmacy

Peri-tumoral leakage during intra-tumoral convection-enhanced delivery has implications for efficacy of peri-tumoral infusion before removal of tumor

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DRUG DELIVERY (2016)

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Article Multidisciplinary Sciences

Monocyte Trafficking, Engraftment, and Delivery of Nanoparticles and an Exogenous Gene into the Acutely Inflamed Brain Tissue - Evaluations on Monocyte-Based Delivery System for the Central Nervous System

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PLOS ONE (2016)

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Review Pharmacology & Pharmacy

Targeting Therapeutics Across the Blood Brain Barrier (BBB), Prerequisite Towards Thrombolytic Therapy for Cerebrovascular Disorders-an Overview and Advancements

K. K. Pulicherla et al.

AAPS PHARMSCITECH (2015)

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Article Nutrition & Dietetics

Carnitine supplementation alleviates lipid metabolism derangements and protects against oxidative stress in non-obese hereditary hypertriglyceridemic rats

Monika Cahova et al.

APPLIED PHYSIOLOGY NUTRITION AND METABOLISM (2015)

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Article Engineering, Biomedical

Enhanced blood-brain barrier penetration and glioma therapy mediated by a new peptide modified gene delivery system

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BIOMATERIALS (2015)

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Article Nanoscience & Nanotechnology

Silver nanoparticles induce tight junction disruption and astrocyte neurotoxicity in a rat blood-brain barrier primary triple coculture model

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INTERNATIONAL JOURNAL OF NANOMEDICINE (2015)

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Article Nanoscience & Nanotechnology

Poly(n-butylcyanoacrylate) nanoparticles for oral delivery of quercetin: preparation, characterization, and pharmacokinetics and biodistribution studies in Wistar rats

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INTERNATIONAL JOURNAL OF NANOMEDICINE (2015)

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Article Chemistry, Multidisciplinary

Remote control of the permeability of the blood-brain barrier by magnetic heating of nanoparticles: A proof of concept for brain drug delivery

Seyed Nasrollah Tabatabaei et al.

JOURNAL OF CONTROLLED RELEASE (2015)

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Review Pharmacology & Pharmacy

Current strategies for targeted delivery of bio-active drug molecules in the treatment of brain tumor

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JOURNAL OF DRUG TARGETING (2015)

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Article Immunology

T-bet Is Required for the Rapid Clearance of Attenuated Rabies Virus from Central Nervous System Tissue

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JOURNAL OF IMMUNOLOGY (2015)

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Article Chemistry, Medicinal

Modulation of Intercellular Junctions by Cyclic-ADT Peptides as a Method to Reversibly Increase Blood-Brain Barrier Permeability

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JOURNAL OF PHARMACEUTICAL SCIENCES (2015)

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Article Medicine, General & Internal

40-year trends in an index of survival for all cancers combined and survival adjusted for age and sex for each cancer in England and Wales, 1971-2011: a population-based study

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LANCET (2015)

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Review Biotechnology & Applied Microbiology

Gold nanoparticles as contrast agents in x-ray imaging and computed tomography

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NANOMEDICINE (2015)

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Review Nanoscience & Nanotechnology

Size, surface charge, and shape determine therapeutic effects of nanoparticles on brain and retinal diseases

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NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2015)

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Assessing sequence plasticity of a virus-like nanoparticle by evolution toward a versatile scaffold for vaccines and drug delivery

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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

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Article Nanoscience & Nanotechnology

The effect of silver nanoparticles (AgNPs) on proliferation and apoptosis of in ovo cultured glioblastoma multiforme (GBM) cells

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NANOSCALE RESEARCH LETTERS (2015)

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Article Surgery

Effects of combination therapy of docetaxel with selenium on the human breast cancer cell lines MDA-MB-231 and MCF-7

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ANNALS OF SURGICAL TREATMENT AND RESEARCH (2015)

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Outer brain barriers in rat and human development

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FRONTIERS IN NEUROSCIENCE (2015)

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Design Strategies and Applications of Circulating Cell-Mediated Drug Delivery Systems

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ACS BIOMATERIALS SCIENCE & ENGINEERING (2015)

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Theranostic USPIO-Loaded Microbubbles for Mediating and Monitoring Blood-Brain Barrier Permeation

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Engineering protein self-assembling in protein-based nanomedicines for drug delivery and gene therapy

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CRITICAL REVIEWS IN BIOTECHNOLOGY (2015)

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Acetyl-L-carnitine and oxaloacetate in post-treatment against LTP impairment in a rat ischemia model. An in vitro electrophysiological study

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Targeted drug delivery to the brain using magnetic nanoparticles

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THERAPEUTIC DELIVERY (2015)

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Article Biochemistry & Molecular Biology

RVG-Peptide-Linked Trimethylated Chitosan for Delivery of siRNA to the Brain

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Article Engineering, Biomedical

Nanoparticles of 2-deoxy-D-glucose functionalized poly(ethylene glycol)-co-poly(trimethylene carbonate) for dual-targeted drug delivery in glioma treatment

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NDRG2 as a marker protein for brain astrocytes

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Approaches to erythrocyte-mediated drug delivery

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EXPERT OPINION ON DRUG DELIVERY (2014)

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EXPERT REVIEW OF NEUROTHERAPEUTICS (2014)

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Selenium-dependent antitumor immunomodulating activity of polysaccharides from roots of A-membranaceus

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Polyethylene glycol-polylactic acid nanoparticles modified with cysteine-arginine-glutamic acid-lysine-alanine fibrin-homing peptide for glioblastoma therapy by enhanced retention effect

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Current approaches to enhance CNS delivery of drugs across the brain barriers

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INTERNATIONAL JOURNAL OF NANOMEDICINE (2014)

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Design, synthesis and biological evaluation for docetaxel- loaded brain targeting liposome with lock-in'' function

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Toxicity of polymeric nanoparticles in vivo and in vitro

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Synergistic Dual-Ligand Doxorubicin Liposomes Improve Targeting and Therapeutic Efficacy of Brain Glioma in Animals

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Transport of nanoparticles through the blood-brain barrier for imaging and therapeutic applications

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NANOSCALE (2014)

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CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2007-2011

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ONCOLOGIST (2014)

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Alpha synuclein is transported into and out of the brain by the blood-brain barrier

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Delivery of an enzyme-IGFII fusion protein to the mouse brain is therapeutic for mucopolysaccharidosis type IIIB

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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

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SCIENTIFIC AMERICAN (2014)

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Angiopep-pluronic F127-conjugated superparamagnetic iron oxide nanoparticles as nanotheranostic agents for BBB targeting

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Hemophilia A: an ideal disease to correct in utero

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FRONTIERS IN PHARMACOLOGY (2014)

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Sequential administration of carbon nanotubes and near-infrared radiation for the treatment of gliomas

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FRONTIERS IN ONCOLOGY (2014)

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Pericytes: brain-immune interface modulators

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FRONTIERS IN INTEGRATIVE NEUROSCIENCE (2014)

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Surface engineering of inorganic nanoparticles for imaging and therapy

Jutaek Nam et al.

ADVANCED DRUG DELIVERY REVIEWS (2013)

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Pharmacokinetics and brain uptake in the rhesus monkey of a fusion protein of arylsulfatase a and a monoclonal antibody against the human insulin receptor

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Article Immunology

IL-17 Promotes Neutrophil Entry into Tumor-Draining Lymph Nodes following Induction of Sterile Inflammation

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JOURNAL OF NEUROIMMUNE PHARMACOLOGY (2013)

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Review Biotechnology & Applied Microbiology

Nanoparticles for imaging and treating brain cancer

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NANOMEDICINE (2013)

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The Ketogenic Diet and Hyperbaric Oxygen Therapy Prolong Survival in Mice with Systemic Metastatic Cancer

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PLOS ONE (2013)

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Structure-based ligand discovery for the Large-neutral Amino Acid Transporter 1, LAT-1

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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

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Receptor-Mediated Delivery of Magnetic Nanoparticles across the Blood-Brain Barrier

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The blood-brain barrier in health and disease

Richard Daneman

ANNALS OF NEUROLOGY (2012)

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Imaging Amyloid Plaque in Alzheimer's Disease Brain with a Biotinylated Aβ Peptide Radiopharmaceutical Conjugated to an IgG-Avidin Fusion Protein

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Effects of the implantation of Ommaya reservoir in children with tuberculous meningitis hydrocephalus: a preliminary study

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CHILDS NERVOUS SYSTEM (2012)

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Going further than Lipinski's rule in drug design

W. Patrick Walters

EXPERT OPINION ON DRUG DISCOVERY (2012)

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Neuroprotective Effects of Pre-Treament with L-Carnitine and Acetyl-L-Carnitine on Ischemic Injury In Vivo and In Vitro

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Review Nanoscience & Nanotechnology

Superparamagnetic iron oxide nanoparticles: magnetic nanoplatforms as drug carriers

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INTERNATIONAL JOURNAL OF NANOMEDICINE (2012)

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p38MAPK, ERK and PI3K Signaling Pathways Are Involved in C5a-Primed Neutrophils for ANCA-Mediated Activation

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PLOS ONE (2012)

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Preparation, Characterization of 2-Deoxy-D-Glucose Functionalized Dimercaptosuccinic Acid-Coated Maghemite Nanoparticles for Targeting Tumor Cells

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PHARMACEUTICAL RESEARCH (2012)

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Article Behavioral Sciences

Acetyl-L-carnitine and alpha-lipoic acid affect rotenone-induced damage in nigral dopaminergic neurons of rat brain, implication for Parkinson's disease therapy

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PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2012)

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Carnitine-induced senescence in glioblastoma cells

Shuichi Yamada et al.

EXPERIMENTAL AND THERAPEUTIC MEDICINE (2012)

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Intra-Arterial Delivery of Bevacizumab after Blood-Brain Barrier Disruption for the Treatment of Recurrent Glioblastoma: Progression-Free Survival and Overall Survival

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WORLD NEUROSURGERY (2012)

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Brain microvascular pericytes in health and disease

Turgay Dalkara et al.

ACTA NEUROPATHOLOGICA (2011)

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Acetyl-L-Carnitine Modulates TP53 and IL10 Gene Expression Induced by 3-NPA Evoked Toxicity in PC12 Cells

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CURRENT NEUROPHARMACOLOGY (2011)

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Cell-mediated drug delivery

Elena V. Batrakova et al.

EXPERT OPINION ON DRUG DELIVERY (2011)

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Therapeutic immune clearance of rabies virus from the CNS

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Current concepts of blood-brain barrier development

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INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY (2011)

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Inorganic nanoparticles for cancer imaging and therapy

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Article Clinical Neurology

Safety and maximum tolerated dose of superselective intraarterial cerebral infusion of bevacizumab after osmotic blood-brain barrier disruption for recurrent malignant glioma Clinical article

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Article Radiology, Nuclear Medicine & Medical Imaging

PET Imaging of Glutaminolysis in Tumors by 18F-(2S,4R)4-Fluoroglutamine

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Article Medicine, Research & Experimental

Large Amino Acid Transporter 1 (LAT1) Prodrugs of Valproic Acid: New Prodrug Design Ideas for Central Nervous System Delivery

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MOLECULAR PHARMACEUTICS (2011)

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Review Medicine, Research & Experimental

Monoclonal antibodies in neuro-oncology Getting past the blood-brain barrier

Lois A. Lampson

MABS (2011)

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Review Neurosciences

Central nervous system pericytes in health and disease

Ethan A. Winkler et al.

NATURE NEUROSCIENCE (2011)

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Review Nutrition & Dietetics

Pharmacological effects and clinical applications of propionyl-L-carnitine

Carmen Mingorance et al.

NUTRITION REVIEWS (2011)

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Article Acoustics

FOCUSED-ULTRASOUND DISRUPTION OF THE BLOOD-BRAIN BARRIER USING CLOSELY-TIMED SHORT PULSES: INFLUENCE OF SONICATION PARAMETERS AND INJECTION RATE

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ULTRASOUND IN MEDICINE AND BIOLOGY (2011)

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Review Nanoscience & Nanotechnology

Viral nanoparticles and virus-like particles: platforms for contemporary vaccine design

Emily M. Plummer et al.

WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY (2011)

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Anatomy and physiology of cerebrospinal fluid

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EUROPEAN ANNALS OF OTORHINOLARYNGOLOGY-HEAD AND NECK DISEASES (2011)

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Mesenchymal stem cells as cellular vehicles for delivery of nanoparticles to brain tumors

Mathilde Roger et al.

BIOMATERIALS (2010)

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Article Developmental Biology

Neuroprotection by Acetyl-L-Carnitine after Traumatic Injury to the Immature Rat Brain

Susanna Scafidi et al.

DEVELOPMENTAL NEUROSCIENCE (2010)

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Article Oncology

Temozolomide Versus Procarbazine, Lomustine, and Vincristine in Recurrent High-Grade Glioma

Michael Brada et al.

JOURNAL OF CLINICAL ONCOLOGY (2010)

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Article Chemistry, Multidisciplinary

Dual-targeting daunorubicin liposomes improve the therapeutic efficacy of brain glioma in animals

Xue Ying et al.

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Article Biochemical Research Methods

Advances in viral transneuronal tracing

Gabriella Ugolini

JOURNAL OF NEUROSCIENCE METHODS (2010)

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Intranasal Delivery to the Central Nervous System: Mechanisms and Experimental Considerations

Shyeilla V. Dhuria et al.

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Article Medicine, Research & Experimental

The Pharmacokinetics of Cell-Penetrating Peptides

Dikran Sarko et al.

MOLECULAR PHARMACEUTICS (2010)

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The role of the blood-CNS barrier in CNS disorders and their treatment

Alan M. Palmer

NEUROBIOLOGY OF DISEASE (2010)

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Review Neurosciences

The blood-brain barrier and immune function and dysfunction

William A. Banks et al.

NEUROBIOLOGY OF DISEASE (2010)

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Review Neurosciences

Approaches to transport therapeutic drugs across the blood-brain barrier to treat brain diseases

Reinhard Gabathuler

NEUROBIOLOGY OF DISEASE (2010)

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Review Neurosciences

Structure and function of the blood-brain barrier

N. Joan Abbott et al.

NEUROBIOLOGY OF DISEASE (2010)

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Stem cell paracrine actions and tissue regeneration

Priya R. Baraniak et al.

REGENERATIVE MEDICINE (2010)

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Review Biochemistry & Molecular Biology

Acylcarnitines: Role in brain

Lauren L. Jones et al.

PROGRESS IN LIPID RESEARCH (2010)

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Review Biochemistry & Molecular Biology

Inorganic nanoparticle-based contrast agents for molecular imaging

Eun Chul Cho et al.

TRENDS IN MOLECULAR MEDICINE (2010)

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Article Chemistry, Inorganic & Nuclear

Boronophenylalanine uptake in C6 glioma model is dramatically increased by L-DOPA preloading

S. Capuani et al.

APPLIED RADIATION AND ISOTOPES (2009)

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Article Oncology

RNOP-09: Pegylated liposomal doxorubicine and prolonged temozolomide in addition to radiotherapy in newly diagnosed glioblastoma - a phase II study

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BMC CANCER (2009)

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Anti-proliferative activity of silver nanoparticles

P. V. AshaRani et al.

BMC CELL BIOLOGY (2009)

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Modulation of blood-brain barrier permeability by neutrophils: in vitro and in vivo studies

Shannon L. Joice et al.

BRAIN RESEARCH (2009)

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Development and characterization of liposomes containing glycols as carriers for diclofenac

M. Manconi et al.

COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS (2009)

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Review Oncology

Experience with irinotecan for the treatment of malignant glioma

James J. Vredenburgh et al.

NEURO-ONCOLOGY (2009)

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Article Biochemistry & Molecular Biology

Blood-Brain Barrier Efflux Transport of Pyrimidine Nucleosides and Nucleobases in the Rat

Zoran B. Redzic et al.

NEUROCHEMICAL RESEARCH (2009)

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Review Pharmacology & Pharmacy

Drug interactions at the blood-brain barrier: Fact or fantasy?

Sara Eyal et al.

PHARMACOLOGY & THERAPEUTICS (2009)

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Review Immunology

The blood-brain and the blood-cerebrospinal fluid barriers: function and dysfunction

Britta Engelhardt et al.

SEMINARS IN IMMUNOPATHOLOGY (2009)

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Review Pharmacology & Pharmacy

Magnetic nanoparticles in MR imaging and drug delivery

Conroy Sun et al.

ADVANCED DRUG DELIVERY REVIEWS (2008)

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Review Neurosciences

Intranasal delivery bypasses the blood-brain barrier to target therapeutic agents to the central nervous system and treat neurodegenerative disease

Leah R. Hanson et al.

BMC NEUROSCIENCE (2008)

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Article Pharmacology & Pharmacy

Antitumour activity of ANG1005, a conjugate between paclitaxel and the new brain delivery vector Angiopep-2

A. Regina et al.

BRITISH JOURNAL OF PHARMACOLOGY (2008)

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Article Chemistry, Medicinal

The first step into the brain: Uptake of NIO-PBCA nanoparticles by endothelial cells in vitro and in vivo, and direct evidence for their blood-brain barrier permeation

Clemens K. Weiss et al.

CHEMMEDCHEM (2008)

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Article Oncology

Molecular targeting and treatment of composite EGFR and EGFRvIII-positive gliomas using boronated monoclonal antibodies

Weilian Yang et al.

CLINICAL CANCER RESEARCH (2008)

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Review Clinical Neurology

A review on the impact of P-glycoprotein on the penetration of drugs into the brain. Focus on psychotropic drugs

Kristian Linnet et al.

EUROPEAN NEUROPSYCHOPHARMACOLOGY (2008)

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Article Pharmacology & Pharmacy

Peptide ligand-mediated liposome distribution and targeting to EGFR expressing tumor in vivo

Shuxian Song et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2008)

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Article Biochemistry & Molecular Biology

Involvement of the low-density lipoprotein receptor-related protein in the transcytosis of the brain delivery vector Angiopep-2

Michel Demeule et al.

JOURNAL OF NEUROCHEMISTRY (2008)

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Review Radiology, Nuclear Medicine & Medical Imaging

Causes and consequences of increased glucose metabolism of cancers

Robert J. Gillies et al.

JOURNAL OF NUCLEAR MEDICINE (2008)

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Article Chemistry, Multidisciplinary

Targeted Gold Nanoparticles Enable Molecular CT Imaging of Cancer

Rachela Popovtzer et al.

NANO LETTERS (2008)

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Review Clinical Neurology

Epidemiology of brain tumors

James L. Fisher et al.

NEUROLOGIC CLINICS (2007)

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Article Anesthesiology

Prolongation of intrathecal and sciatic nerve blocks using a complex of levobupivacaine with maltosyl-β-cyclodextrin in rats

Ken Karashima et al.

ANESTHESIA AND ANALGESIA (2007)

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Review Pharmacology & Pharmacy

Blood-brain barrier delivery

William M. Pardridge

DRUG DISCOVERY TODAY (2007)

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Article Acoustics

Noninvasive, transcranial and localized opening of the blood-brain barrier using focused ultrasound in mice

James J. Choi et al.

ULTRASOUND IN MEDICINE AND BIOLOGY (2007)

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Review Chemistry, Multidisciplinary

Contribution of carrier-mediated transport systems to the blood-brain barrier as a supporting and protecting interface for the brain; Importance for CNS drug discovery and development

Sumio Ohtsuki et al.

PHARMACEUTICAL RESEARCH (2007)

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Review Chemistry, Multidisciplinary

Blood-brain barrier transport of therapeutics via receptor-mediation

Angela R. Jones et al.

PHARMACEUTICAL RESEARCH (2007)

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Article Oncology

Neurospheres enriched in cancer stem-like cells are highly effective in eliciting a dendritic cell-mediated immune response against malignant gliomas

Serena Pellegatta et al.

CANCER RESEARCH (2006)

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Article Pharmacology & Pharmacy

Molecular Trojan horses for blood-brain barrier drug delivery

William M. Pardridge

CURRENT OPINION IN PHARMACOLOGY (2006)

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Review Pharmacology & Pharmacy

Endocytosis at the blood-brain barrier: From basic understanding to drug delivery strategies

Mathew W. Smith et al.

JOURNAL OF DRUG TARGETING (2006)

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Article Biochemical Research Methods

Quantitative production of macrophages or neutrophils ex vivo using conditional Hoxb8

GG Wang et al.

NATURE METHODS (2006)

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Article Clinical Neurology

Carnitine treatment inhibits increases in cerebral carnitine esters and glutamate detected by mass spectrometry after hypoxia-ischemia in newborn rats

MS Wainwright et al.

STROKE (2006)

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Review Neurosciences

Astrocyte-endothelial interactions at the blood-brain barrier

NJ Abbott et al.

NATURE REVIEWS NEUROSCIENCE (2006)

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Article Cardiac & Cardiovascular Systems

Tissue-type plasminogen activator crosses the intact blood-brain barrier by low-density lipoprotein receptor-related protein-mediated transcytosis

K Benchenane et al.

CIRCULATION (2005)

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Article Chemistry, Multidisciplinary

Gold nanocages: Bioconjugation and their potential use as optical imaging contrast agents

J Chen et al.

NANO LETTERS (2005)

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Review Pharmacology & Pharmacy

The use of cell-penetrating peptides for drug delivery

J Temsamani et al.

DRUG DISCOVERY TODAY (2004)

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Article Neurosciences

Neuronal expression of the drug efflux transporter P-glycoprotein in the rat hippocampus after limbic seizures

HA Volk et al.

NEUROSCIENCE (2004)

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Review Neurosciences

The blood-brain barrier: an overview - Structure, regulation, and clinical implications

P Ballabh et al.

NEUROBIOLOGY OF DISEASE (2004)

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Article Biochemical Research Methods

In vitro cytotoxicity and in vivo distribution after direct delivery of PEG-camptothecin conjugates to the rat brain

AB Fleming et al.

BIOCONJUGATE CHEMISTRY (2004)

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Review Medicine, General & Internal

Meningiomas

IR Whittle et al.

LANCET (2004)

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Article Biophysics

Charge-dependent translocation of the Trojan peptide penetratin across lipid membranes

H Binder et al.

BIOPHYSICAL JOURNAL (2003)

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Review Pharmacology & Pharmacy

Pluronic® block copolymers as modulators of drug efflux transporter activity in the blood-brain barrier

AV Kabanov et al.

ADVANCED DRUG DELIVERY REVIEWS (2003)

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Review Biochemistry & Molecular Biology

Structure and function of RGD peptides involved in bone biology

P Schaffner et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2003)

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Article Chemistry, Medicinal

Contributions of saturable active secretion, passive transcellular, and paracellular diffusion to the overall transport of furosemide across adenocarcinoma (Caco-2) cells

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