4.7 Article

Blood flow restriction accelerates aerobic training-induced adaptation of (V) over dotO2 kinetics at the onset of moderate-intensity exercise

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SCIENTIFIC REPORTS
卷 12, 期 1, 页码 -

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NATURE PORTFOLIO
DOI: 10.1038/s41598-022-22852-3

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  1. JSPS KAKENHI [23700788]
  2. Kozuki Foundation for Sports and Education
  3. Science Research Promotion Fund from the Promotion and Mutual Aid Corporation for Private Schools of Japan
  4. Mitsui Life Social Welfare Foundation

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This study aimed to investigate whether blood flow restriction (BFR) during moderate-intensity aerobic training can accelerate the adaptation of the time constant (tau) of phase II oxygen uptake (<(V) over dot>O-2) kinetics in the moderate-intensity exercise domain. The results showed that tau significantly decreased in the BFR group at the mid-point of training, while the CON group showed a decrease at the end of training. The BFR group had significantly lower tau than the CON group at the mid-point, but there was no significant difference between the two groups at the end of training.
It is unclear whether blood flow restriction (BFR) accelerates the adaptation of the time constant (tau) of phase II oxygen uptake (<(V) over dot>O-2) kinetics in the moderate-intensity exercise domain via moderate-intensity aerobic training. Therefore, healthy participants underwent moderate-intensity [45-60% <(V) over dot>O-2 Reserve] aerobic cycle training with or without BFR (BFR group, n=9; CON group, n = 9) for 8 weeks to evaluate O-2 kinetics during moderate-intensity cycle exercise before (Pre) and after 4 (Mid) and 8 (Post) weeks of training. Both groups trained for 30 min, 3 days weekly. BFR was performed for 5 min every 10 min by applying cuffs to the upper thighs. The tau significantly decreased by Mid in the BFR group (23.7 +/- 2.9 s [Pre], 15.3 +/- 1.8s [Mid], 15.5 +/- 1.4s [Post], P < 0.01) and by Post in the CON group (27.5 +/- 2.0 s [Pre], 22.1 +/- 0.7 s [Mid], 18.5 +/- 1.9 s [Post], P < 0.01). Notably, the BFR group's tau was significantly lower than that of the CON group at Mid (P < 0.01) but not at Post. In conclusion, BFR accelerates the adaptation of the <(V) over dot>O-2 kinetics of phase II by moderate-intensity aerobic training.

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