4.6 Article

Humidity-induced direct modification of the optical response of plasmonic nanorod metamaterials

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Summary: Plasmonic sensing based on nanostructures is a powerful tool for ultrasensitive label-free biomolecule detection in clinical diagnostics and biomedical research. In this study, we fabricated and characterized gold nanorod hyperbolic metamaterials (NHMMs) and demonstrated their high sensitivity for bulk refractive index and label-free biomolecular detection. By integrating the sensor in microfluidics, we achieved a bulk sensitivity of 41,600 nm/RIU and a figure of merit of 416 RIU-1. By bio-functionalizing the sensor surface, we successfully monitored the binding of streptavidin at low concentrations in real time. The developed plasmonic NHMM sensor shows great potential for highly sensitive detection of bulk solutions and biomolecules.

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