期刊
NUTRIENTS
卷 14, 期 21, 页码 -出版社
MDPI
DOI: 10.3390/nu14214555
关键词
polycystic ovary syndrome; obesity; overweight; diet; probiotics; synbiotic
PCOS is a common endocrine and metabolic disorder in premenopausal women, closely related to diet and lifestyle. Obesity is linked to PCOS, with abdominal obesity contributing to inflammatory changes. Improving diet, weight loss, and probiotic intake play important roles in managing PCOS patients.
Polycystic ovarian syndrome (PCOS) is one of the most common heterogeneous endocrine and metabolic disorders in premenopausal women. It is a complex multifactorial disorder with strong epigenetic and environmental influences, including factors related to eating habits and lifestyle. There is a close relationship between obesity and PCOS. Weight gain and obesity are often clinical symptoms manifested by biochemical markers. Moreover, abdominal obesity in women with PCOS is involved in the development of inflammatory changes. A significant share of balanced therapies correcting the lifestyle of patients is suggested, e.g., with the implementation of appropriate diets to minimize exposure to inflammatory factors and prevent abnormal immune system stimulation. In the case of obese patients with PCOS, planning a diet program and supporting the motivation to change eating habits play an important role to lose weight and lower BMI. Probiotics/synbiotic supplementation may enhance weight loss during the diet program and additionally positively affect metabolic and inflammatory factors by improving the intestinal microbiome.
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