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Iodine and Iodine Deficiency: A Comprehensive Review of a Re-Emerging Issue

期刊

NUTRIENTS
卷 14, 期 17, 页码 -

出版社

MDPI
DOI: 10.3390/nu14173474

关键词

iodine deficiency disorders; urinary iodine concentration; thyroid stimulating hormone; iodized salt; supplementation

资金

  1. Department of Defense Center Alliance for Nutrition and Dietary Supplements Research of the Defense Medical Research and Development Program

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This paper reviews recent studies on the re-emerging issue of iodine deficiency and declining intake among populations in developed countries. Iodine nutrition is becoming increasingly important within industrialized countries, but declining dietary patterns and food manufacturing practices have resulted in decreased iodine intake.
Iodine is a mineral nutrient essential for the regulation of a variety of key physiological functions including metabolism and brain development and function in children and adults. As such, iodine intake and status within populations is an area of concern and research focus. This paper will review recently published studies that focus on the re-emerging issue of iodine deficiency as a global concern and declining intake among populations in developed countries. Historically, the implementation of salt-iodization programs worldwide has reduced the incidence of iodine deficiency, but 30% of the world's population is still at risk. Iodine nutrition is a growing issue within industrialized countries including the U.S. as a result of declining iodine intake, in part due to changing dietary patterns and food manufacturing practices. Few countries mandate universal salt iodization policies, and differing agriculture and industry practices and regulations among countries have resulted in inconsistencies in supplementation practices. In the U.S., in spite of salt-iodization policies, mild-to-moderate iodine deficiency is common and appears to be increasing. European countries with the highest incidence of deficiency lack iodization programs. Monitoring the iodine status of at-risk populations and, when appropriate, public health initiatives, appear to be warranted.

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