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Arnaud Bourdin et al.
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J. A. Kroes et al.
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J. Mark FitzGerald et al.
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Stephanie Chen et al.
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Hart S. Dengler et al.
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Sarah H. Ross et al.
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Th9 and other IL-9-producing cells in allergic asthma
Sonja Koch et al.
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Brian D. Hondowicz et al.
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Sally Wenzel et al.
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Stephen T. Holgate et al.
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Shigeru Ashino et al.
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Kristof Raemdonck et al.
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DongYoub Lee et al.
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Identification of Asthma Phenotypes Using Cluster Analysis in the Severe Asthma Research Program
Wendy C. Moore et al.
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Hubert Chen et al.
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DJ Hele et al.
BRITISH JOURNAL OF PHARMACOLOGY (2001)