Recent Advancement in Palladium-Catalyzed C-C Bond Activation of Strained Ring Systems: Three- and Four-Membered Carbocycles as Prominent C3/C4 Building Blocks

In recent years, transition metal-catalyzed strong C-C bond activation has significantly attracted the attention of synthetic chemists. This protocol enables simultaneous and direct functionalization of two different M-C bonds. Among different types of C-C bond activation strategies, strain-driven C-C bond activation has resulted in various otherwise difficult transformations. In this context, palladium catalyst has been extensively used and studied due to its robust reactivity and selectivity. Herein we have briefly discussed palladium-catalyzed C-C bond activation of three- and four-membered cycloalkane derivatives.

Automated summary

In recent years, the strong C-C bond activation catalyzed by transition metals has gained significant attention in the field of synthetic chemistry. This protocol allows for the simultaneous and direct functionalization of two different M-C bonds. Among various strategies for C-C bond activation, strain-driven C-C bond activation has enabled otherwise challenging transformations. Palladium catalysts have been extensively explored and utilized due to their robust reactivity and selectivity. In this article, we briefly discuss the palladium-catalyzed C-C bond activation of three- and four-membered cycloalkane derivatives.