4.8 Article

Global mortality of snakebite envenoming between 1990 and 2019

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NATURE COMMUNICATIONS
卷 13, 期 1, 页码 -

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NATURE PORTFOLIO
DOI: 10.1038/s41467-022-33627-9

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资金

  1. Bill & Melinda Gates Foundation
  2. Romanian National Authority for Scientific Research and Innovation, CNDS-UEFISCDI [PN-III-P4-ID-PCCF-2016-0084]
  3. Fundacao para a Ciencia e a Tecnologia, I.P. [UIDP/04378/2020, UIDB/04378/2020]
  4. Associate Laboratory Institute for Health and Bioeconomy i4HB [LA/P/0140/2020]
  5. FCT/MCTES (Ministerio da Ciencia, Tecnologia e Ensino Superior) [UIDB/50006/2020]
  6. UGC Centre of Advanced Study (Phase II)
  7. Panama's Secretaria Nacional de Ciencia, Tecnologia e Innovacion (SENACYT)
  8. Egyptian Fulbright Mission Program

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Snakebite envenoming is a significant preventable cause of death. The World Health Organization aims to reduce snakebite mortality by half by 2030. Based on the latest data, it is estimated that 63,400 people died globally from snakebites in 2019, with an age-standardized mortality rate of 0.8 deaths per 100,000 population, representing a 36% decrease since 1990. India had the highest number of snakebite deaths in 2019.
Snakebite envenoming is an important cause of preventable death. The World Health Organization (WHO) set a goal to halve snakebite mortality by 2030. We used verbal autopsy and vital registration data to model the proportion of venomous animal deaths due to snakes by location, age, year, and sex, and applied these proportions to venomous animal contact mortality estimates from the Global Burden of Disease 2019 study. In 2019, 63,400 people (95% uncertainty interval 38,900-78,600) died globally from snakebites, which was equal to an age-standardized mortality rate (ASMR) of 0.8 deaths (0.5-1.0) per 100,000 and represents a 36% (2-49) decrease in ASMR since 1990. India had the greatest number of deaths in 2019, equal to an ASMR of 4.0 per 100,000 (2.3-5.0). We forecast mortality will continue to decline, but not sufficiently to meet WHO's goals. Improved data collection should be prioritized to help target interventions, improve burden estimation, and monitor progress.

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