4.8 Article

Ectopic expression of sericin enables efficient production of ancient silk with structural changes in silkworm

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

New insight into the mechanism of in vivo fibroin self-assembly and secretion in the silkworm, Bombyx mori

Zhanzhang Hao et al.

Summary: Silk fibroin of the silkworm consists of different components, each playing distinct roles in silk processing. The hydrophilic NTDs and CTDs are shown to be located differently in micelles, providing electrostatic repulsion and controlling solubility, respectively. This elucidates the underlying mechanisms of silkworm silk processing.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

Article Biochemistry & Molecular Biology

P25 Gene Knockout Contributes to Human Epidermal Growth Factor Production in Transgenic Silkworms

Meiyu Wu et al.

Summary: The expression of human epidermal growth factor (hEGF) in a P25 gene knockout silkworm was reported, where the knockout of the P25 gene increased hEGF production while maintaining similar physical properties of cocoon silks compared to wild type silkworms. This suggests that P25 gene knockout silkworms could be an efficient bioreactor for producing exogenous proteins and protein-containing silk biomaterials.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Article Biochemistry & Molecular Biology

Mutation in Bombyx mori fibrohexamerin (P25) gene causes reorganization of rough endoplasmic reticulum in posterior silk gland cells and alters morphology of fibroin secretory globules in the silk gland lumen

Valeriya Zabelina et al.

Summary: The study reveals that while Fhx is dispensable for silk formation, it contributes to the stability of fibroin complexes and affects the morphology of fibroin secretory globules in the PSG lumen.

INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY (2021)

Review Biochemistry & Molecular Biology

Structure of Silk I (Bombyx mori Silk Fibroin before Spinning) -Type II β-Turn, Not α-Helix-

Tetsuo Asakura

Summary: Scientists are focusing on the structural determinations of Bombyx mori silk fibroin to further develop its applications due to its excellent physical properties. There are discrepancies in the silk I structural model, but the author emphasizes that it should be type II beta-turn structure.

MOLECULES (2021)

Article Biochemical Research Methods

Production of a correctly assembled fibrinogen using transgenic silkworms

Sachi Minagawa et al.

TRANSGENIC RESEARCH (2020)

Article Materials Science, Biomaterials

Photoelectric Silk via Genetic Encoding and Bioassisted Plasmonics

Jung Woo Leem et al.

ADVANCED BIOSYSTEMS (2020)

Article Biochemistry & Molecular Biology

Structural and Mechanical Properties of Silk from Different Instars of Bornbyx mori

Zhangchuan Peng et al.

BIOMACROMOLECULES (2019)

Article Engineering, Biomedical

The Biomedical Use of Silk: Past, Present, Future

Chris Holland et al.

ADVANCED HEALTHCARE MATERIALS (2019)

Article Chemistry, Multidisciplinary

Fibrous Protein Self-Assembly in Biomimetic Materials

Thomas O. Mason et al.

ADVANCED MATERIALS (2018)

Review Chemistry, Multidisciplinary

Silkworm silk-based materials and devices generated using bio-nanotechnology

Wenwen Huang et al.

CHEMICAL SOCIETY REVIEWS (2018)

Article Biochemistry & Molecular Biology

Soft freezing-induced self-assembly of silk fibroin for tunable gelation

Xiufang Li et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2018)

Review Polymer Science

Silk and Silk-Like Supramolecular Materials

Tanner D. Fink et al.

MACROMOLECULAR RAPID COMMUNICATIONS (2018)

Article Multidisciplinary Sciences

Mass spider silk production through targeted gene replacement in Bombyx mori

Jun Xu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Article Multidisciplinary Sciences

Bioengineered silkworms with butterfly cytotoxin-modified silk glands produce sericin cocoons with a utility for a new biomaterial

Ryosuke Otsuki et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Article Biochemistry & Molecular Biology

Tyrosine Templating in the Self-Assembly and Crystallization of Silk Fibroin

Benjamin P. Partlow et al.

BIOMACROMOLECULES (2016)

Review Biochemistry & Molecular Biology

Silk Spinning in Silkworms and Spiders

Marlene Andersson et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)

Article Biochemistry & Molecular Biology

Modulation of Self-Assembly Process of Fibroin: An Insight for Regulating the Conformation of Silk Biomaterials

Priyanka Dubey et al.

BIOMACROMOLECULES (2015)

Article Biochemistry & Molecular Biology

Influence factors analysis on the formation of silk I structure

Jinfa Ming et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2015)

Review Entomology

Advances in Silkworm Studies Accelerated by the Genome Sequencing of Bombyx mori

Qingyou Xia et al.

ANNUAL REVIEW OF ENTOMOLOGY, VOL 59, 2014 (2014)

Article Chemistry, Multidisciplinary

Colored Fluorescent Silk Made by Transgenic Silkworms

Tetsuya Iizuka et al.

ADVANCED FUNCTIONAL MATERIALS (2013)

Article Biochemistry & Molecular Biology

Silk Self-Assembly Mechanisms and Control From Thermodynamics to Kinetics

Qiang Lu et al.

BIOMACROMOLECULES (2012)

Article Multidisciplinary Sciences

Silkworms transformed with chimeric silkworm/spider silk genes spin composite silk fibers with improved mechanical properties

Florence Teule et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Biotechnology & Applied Microbiology

Production of a Non-Triple Helical Collagen α Chain in Transgenic Silkworms and Its Evaluation as a Gelatin Substitute for Cell Culture

Takahiro Adachi et al.

BIOTECHNOLOGY AND BIOENGINEERING (2010)

Article Biochemistry & Molecular Biology

Transgenic silkworms (Bombyx mori) produce recombinant spider dragline silk in cocoons

Hongxiu Wen et al.

MOLECULAR BIOLOGY REPORTS (2010)

Review Multidisciplinary Sciences

New Opportunities for an Ancient Material

Fiorenzo G. Omenetto et al.

SCIENCE (2010)

Article Biochemistry & Molecular Biology

Production of a recombinant mouse monoclonal antibody in transgenic silkworm cocoons

Masashi Iizuka et al.

FEBS JOURNAL (2009)

Article Chemistry, Physical

Comparing the rheology of native spider and silkworm spinning dope

C. Holland et al.

NATURE MATERIALS (2006)

Article Biochemistry & Molecular Biology

A fibroin secretion-deficient silkworm mutants Nd-s(D), provides an efficient system for producing recombinant proteins

S Inoue et al.

INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY (2005)

Article Multidisciplinary Sciences

Mechanism of silk processing in insects and spiders

HJ Jin et al.

NATURE (2003)

Article Biotechnology & Applied Microbiology

Transgenic silkworms produce recombinant human type III procollagen in cocoons

M Tomita et al.

NATURE BIOTECHNOLOGY (2003)

Article Biotechnology & Applied Microbiology

Germline transformation of the silkworm Bombyx mori L-using a piggyBac transposon-derived vector

T Tamura et al.

NATURE BIOTECHNOLOGY (2000)