期刊
VIRUS RESEARCH
卷 321, 期 -, 页码 -出版社
ELSEVIER
DOI: 10.1016/j.virusres.2022.198907
关键词
SARS-CoV-2; S; L452R; Mutational scanning; VOC
类别
资金
- Brazilian Coordination for the Improvement of Higher-Level Personnel (CAPES)
- Foundation for Research Support of the State of Rio Grande do Sul (FAPERGS)
- Brazilian National Council for Scientific Development (CNPq)
- initiative of Rede Corona-omica BR MCTI/FINEP affiliated to RedeVirus/MCTI [FINEP =01.20.0029.000462/20, CNPq=404096/2020-4]
- FAPERGS [21/2551-0000081-3]
- IMMUNESHARE - MCTI Trial (SEFEP/MCTI/CNPq) [401558/2021-5]
This study aims to analyze and summarize information about the genetic characteristics, amino acid mutations, and epidemiological data of the SARS-CoV-2 Omicron variant, providing scientific findings to enrich our understanding of this variant.
Recently, SARS-CoV-2 Omicron variant (B.1.1.529) was first identified in Botswana in November 2021. In a short period of time, this highly mutated variant replaced the previous dominant Delta variant, causing an exponential increase in the number of COVID-19 cases, resulting in a new wave of pandemic. This current research article aims to analyze and summarize information about the genetic characteristics, amino acid mutations and epidemiological data providing scientific findings to enrich the SARS-CoV-2 knowledge. More importantly, we describe here, for the first time, the identification of a new Omicron variant of concern: Omicron-L452R in Brazil.
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