4.7 Article

Oncolytic avian reovirus ΣA-modulated fatty acid metabolism through the PSMB6/Akt/SREBP1/acetyl-CoA carboxylase pathway to increase energy production for virus replication

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Virology

p17-Modulated Hsp90/Cdc37 Complex Governs Oncolytic Avian Reovirus Replication by Chaperoning p17, Which Promotes Viral Protein Synthesis and Accumulation of Viral Proteins σC and σA in Viral Factories

Wei-Ru Huang et al.

Summary: This study determines the essential role of heat shock protein 90 (Hsp90) in avian reovirus (ARV) replication by chaperoning the ARV p17 protein. The Hsp90/Cdc37 chaperone complex protects p17 from degradation and enhances viral protein stability and virus production. Depletion of Hsp90 prevents viral proteins sigma A, sigma C, and p17 from colocalizing with sigma NS in viral factories.

JOURNAL OF VIROLOGY (2022)

Article Microbiology

Molecular chaperone TRiC governs avian reovirus replication by protecting outer-capsid protein ΣC and inner core protein ΣA and non-structural protein ΣNS from ubiquitin- proteasome degradation

Wei-Ru Huang et al.

Summary: This study demonstrates that the eukaryotic chaperonin T-complex protein-1 (TCP-1) ring complex (TRiC) is essential for avian reovirus (ARV) replication by stabilizing outer-capsid protein aC, inner core protein aA, and the non-structural protein aNS of ARV.

VETERINARY MICROBIOLOGY (2022)

Article Medicine, Research & Experimental

The oncolytic efficacy and safety of avian reovirus and its dynamic distribution in infected mice

Ruimin Cai et al.

EXPERIMENTAL BIOLOGY AND MEDICINE (2019)

Review Oncology

Cell membrane modulation as adjuvant in cancer therapy

Sara Zalba et al.

CANCER TREATMENT REVIEWS (2017)

Review Oncology

The multifaceted roles of fatty acid synthesis in cancer

Florian Roehrig et al.

NATURE REVIEWS CANCER (2016)

Review Virology

Viral activation of cellular metabolism

Erica L. Sanchez et al.

VIROLOGY (2015)

Review Cell Biology

Hypoxia, lipids, and cancer: surviving the harsh tumor microenvironment

Daniel Ackerman et al.

TRENDS IN CELL BIOLOGY (2014)

Review Biochemistry & Molecular Biology

Viral effects on metabolism: changes in glucose and glutamine utilization during human cytomegalovirus infection

Yongjun Yu et al.

TRENDS IN MICROBIOLOGY (2011)

Article Biochemistry & Molecular Biology

Sterol Regulatory Element-binding Protein (SREBP)-1-mediated Lipogenesis Is Involved in Cell Senescence

You-Mie Kim et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Review Endocrinology & Metabolism

The Akt-SREBP nexus: cell signaling meets lipid metabolism

James R. Krycer et al.

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2010)

Article Cell Biology

Akt2 Is Required for Hepatic Lipid Accumulation in Models of Insulin Resistance

Karla F. Leavens et al.

CELL METABOLISM (2009)

Article Biochemistry & Molecular Biology

Fatty acid metabolism: target for metabolic syndrome

Salih J. Wakil et al.

JOURNAL OF LIPID RESEARCH (2009)

Article Multidisciplinary Sciences

Visualization of ATP levels inside single living cells with fluorescence resonance energy transfer-based genetically encoded indicators

Hiromi Imamura et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Biochemical Research Methods

Proteasome inhibition reduces avian reovirus replication and apoptosis induction in cultured cells

Yu I. Chen et al.

JOURNAL OF VIROLOGICAL METHODS (2008)

Article Virology

Crystal Structure of the Avian Reovirus Inner Capsid Protein σA

Pablo Guardado-Calvo et al.

JOURNAL OF VIROLOGY (2008)

Article Multidisciplinary Sciences

Continuous fat oxidation in acetyl-CoA carboxylase 2 knockout mice increases total energy expenditure, reduces fat mass, and improves insulin sensitivity

Cheol Soo Choi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Oncology

ATP citrate lyase inhibition can suppress tumor cell growth

G Hatzivassiliou et al.

CANCER CELL (2005)

Article Multidisciplinary Sciences

Acetyl-CoA carboxylase 2 mutant mice are protected against obesity and diabetes induced by high-fat/high-carbohydrate diets

L Abu-Elheiga et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Article Biochemistry & Molecular Biology

Acetyl-CoA carboxylase β gene is regulated by sterol regulatory element-binding protein-1 in liver

SY Oh et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Multidisciplinary Sciences

The subcellular localization of acetyl-CoA carboxylase 2

L Abu-Elheiga et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)