Bricks out of the wall: polysaccharide extramural functions

Plant polysaccharides are components of plant cell walls and/or store energy. However, this oversimplified classification neglects the fact that some cell wall polysaccharides and glycoproteins can localize outside the relatively sharp boundaries of the apoplastic moiety, where they adopt functions not directly re-lated to the cell wall. Such polysaccharide multifunctionality (or 'moonlighting') is overlooked in current research, and in most cases the underlying mechanisms that give rise to unconventional ex muro trafficking, targeting, and functions of polysaccharides and glycoproteins remain elusive. This review highlights major examples of the extramural occurrence of various glycan cell wall components, discusses the possible significance and implications of these phenomena for plant physiology, and lists exciting open questions to be addressed by future research.

Automated summary

Plant polysaccharides are not only components of plant cell walls and energy storage, but also have functions outside the cell wall. However, the mechanisms underlying the unconventional trafficking, targeting, and functions of these polysaccharides and glycoproteins are not well understood.