4.6 Review

Neural consequences of chronic sleep disruption

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Behavioral Sciences

Effect of chronic sleep deprivation and sleep recovery on hippocampal CA3 neurons, spatial memory and anxiety-like behavior in rats

Suresh Konakanchi et al.

Summary: Sleep deprivation-induced degenerative changes in the brain can lead to memory impairment, anxiety, and decreased quality of life. Studies have shown that chronic sleep deprivation can negatively affect dendritic arborization of CA3 neurons in the hippocampus, increase anxiety-like behavior and oxidative stress. Sleep recovery partially improves these effects.

NEUROBIOLOGY OF LEARNING AND MEMORY (2022)

Article Cell Biology

Slow-wave sleep affects synucleinopathy and regulates proteostatic processes in mouse models of Parkinson's disease

Marta M. Morawska et al.

Summary: Enhancing slow-wave sleep in murine models of Parkinson's disease reduces pathological alpha-synuclein accumulation and may improve disease progression through mechanisms such as promoting glymphatic clearance.

SCIENCE TRANSLATIONAL MEDICINE (2021)

Article Cell Biology

Topological reorganizations of mitochondria isolated from rat brain after 72 hours of paradoxical sleep deprivation, revealed by electron cryo-tomography

Zhuoyang Lu et al.

Summary: Sleep deprivation affects the structure and respiratory function of mitochondria, with more significant changes observed in the hippocampus. Quantifying these structural reorganizations using morphometric parameters can provide insights into the effects of sleep deprivation on mitochondrial inner membrane architecture and respiratory functions in different brain regions.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2021)

Article Endocrinology & Metabolism

Neurobehavioral alterations in a mouse model of chronic partial sleep deprivation

Shiyana Arora et al.

Summary: The study explored the impact of chronic partial sleep deprivation (CPSD) induced by the night shift paradigm on female Swiss albino mice. Results showed that CPSD led to hyperactive behavioral profile, decreased mitochondrial enzyme activity and serotonin levels, as well as increased oxidative stress and inflammatory markers in the brain tissue. These findings suggest a potential link between CPSD and hyperactive behavioral symptoms resembling mania and psychosis.

METABOLIC BRAIN DISEASE (2021)

Article Clinical Neurology

Late-in-life neurodegeneration after chronic sleep loss in young adult mice

Jessica E. Owen et al.

Summary: Short-term sleep loss impacts A beta and tau levels, while sleep disturbances predict cognitive decline. Chronic short sleep exposure leads to late-life neurodegeneration and disrupts amyloid and tau homeostasis.
Review Neurosciences

Mitochondria: new players in homeostatic regulation of firing rate set points

Antonella Ruggiero et al.

Summary: Neural circuit functions are stabilized through a process called firing rate homeostasis, in which mitochondria seem to play a central role. While mitochondria are known to regulate certain neuronal variables, the specific mitochondrial signaling pathways essential for firing rate homeostasis remain largely unknown.

TRENDS IN NEUROSCIENCES (2021)

Article Multidisciplinary Sciences

Net decrease in spine-surface GluA1-containing AMPA receptors after post-learning sleep in the adult mouse cortex

Daisuke Miyamoto et al.

Summary: The study indicates that sleep helps strengthen synapses after learning, and molecular changes in spines during sleep are related to performance after sleep. Sleep assists in enhancing the effects of learning on synapses, while also weakening remaining spines.

NATURE COMMUNICATIONS (2021)

Article Medicine, Research & Experimental

β-adrenergic Receptor Activity in the Hippocampal Dentate Gyrus Participates in Spatial Learning and Memory Impairment in Sleep-deprived Rats

Huan-Jun Lu et al.

Summary: Sleep deprivation can lead to cognitive impairment, specifically affecting hippocampus-dependent learning and memory. Studies have shown that beta-adrenergic signaling plays a crucial role in regulating spatial learning and memory, with activation of beta-AR improving memory deficits in sleep-deprived rats.

EXPERIMENTAL NEUROBIOLOGY (2021)

Article Behavioral Sciences

Chronic sleep deprivation exacerbates cognitive and synaptic plasticity impairments in APP/PS1 transgenic mice

Chun Wang et al.

Summary: The study found that chronic sleep deprivation significantly exacerbated cognitive impairments in APP/PS1 mice by accelerating the development of AD pathologies, reducing the expression of PSD95, and aggravating LTP suppression in the hippocampus. At the same time, chronic sleep deprivation also impaired cognitive functions and synaptic plasticity in wild type mice by down-regulating the level of PSD95 and activating microglia. These findings clarify the electrophysiological and molecular mechanisms of exacerbated cognitive deficits in AD caused by chronic sleep deprivation.

BEHAVIOURAL BRAIN RESEARCH (2021)

Article Neurosciences

Melatonin ameliorates anxiety-like behaviors induced by sleep deprivation in mice: Role of oxidative stress, neuroinflammation, autophagy and apoptosis

Xintong Wang et al.

Summary: The study suggests a link between anxiety disorders and sleep deprivation, with melatonin supplementation showing potential in ameliorating the effects. Melatonin was found to attenuate anxiety-like behaviors induced by sleep deprivation by improving oxidative stress, NF-kappa B pathway activation, neuroinflammation, apoptosis, and excessive autophagy.

BRAIN RESEARCH BULLETIN (2021)

Article Neurosciences

No loss of orexin/hypocretin, melanin-concentrating hormone or locus coeruleus noradrenergic neurons in a rat model of chronic sleep restriction

Samuel Deurveilher et al.

Summary: The study did not find significant differences in the numbers of orexin and locus coeruleus noradrenergic neurons in rats following one or four cycles of a sleep restriction protocol. Sleep restriction also did not affect the densities of orexin axon terminals and noradrenergic dendrites in the brain cortex.

EUROPEAN JOURNAL OF NEUROSCIENCE (2021)

Article Multidisciplinary Sciences

Observing changes in human functioning during induced sleep deficiency and recovery periods

Jeremi K. Ochab et al.

Summary: Prolonged periods of sleep restriction have negative impacts on circadian rhythmicity, waking alertness, and cognitive function. Despite a week of recovery, the effects of chronic sleep loss on various measures in the human body are not fully reversed.

PLOS ONE (2021)

Article Cell Biology

Differential effect of sleep deprivation on place cell representations, sleep architecture, and memory in young and old mice

Robin K. Yuan et al.

Summary: Poor sleep quality is associated with age-related cognitive decline, but the possibility of reversing these changes is unknown. This study suggests that sleep deprivation may help ameliorate age-related memory deficits and allow hippocampal representations to adapt to changing environments. Successful memory performance is correlated with specific cellular phenotypes and spindle counts.

CELL REPORTS (2021)

Article Neurosciences

Phagocytic elimination of synapses by microglia during sleep

Mohammed E. Choudhury et al.

Article Medicine, Research & Experimental

Norepinephrine metabolite DOPEGAL activates AEP and pathological Tau aggregation in locus coeruleus

Seong Su Kang et al.

JOURNAL OF CLINICAL INVESTIGATION (2020)

Article Behavioral Sciences

Immediate and Long-Lasting Cognitive Consequences of Adolescent Chronic Sleep Restriction

Kerry A. Howard et al.

BEHAVIORAL NEUROSCIENCE (2019)

Article Multidisciplinary Sciences

The sleep-wake cycle regulates brain interstitial fluid tau in mice and CSF tau in humans

Jerrah K. Holth et al.

SCIENCE (2019)

Article Neurosciences

Early Life Sleep Deprivation: Role of Oxido-Inflammatory Processes

Fatin Atrooz et al.

NEUROSCIENCE (2019)

Article Biochemistry & Molecular Biology

The ameliorative effect of fluoxetine on neuroinflammation induced by sleep deprivation

Maosheng Xia et al.

JOURNAL OF NEUROCHEMISTRY (2018)

Article Clinical Neurology

Myelin modifications after chronic sleep loss in adolescent mice

Michele Bellesi et al.

Article Multidisciplinary Sciences

Microglia remodel synapses by presynaptic trogocytosis and spine head filopodia induction

Laetitia Weinhard et al.

NATURE COMMUNICATIONS (2018)

Article Clinical Neurology

Myelin modifications after chronic sleep loss in adolescent mice

Michele Bellesi et al.

Article Multidisciplinary Sciences

Ultrastructural evidence for synaptic scaling across the wake/sleep cycle

Luisa de Vivo et al.

SCIENCE (2017)

Article Multidisciplinary Sciences

Homer1a drives homeostatic scaling-down of excitatory synapses during sleep

Graham H. Diering et al.

SCIENCE (2017)

Article Clinical Neurology

Degeneration in arousal neurons in chronic sleep disruption modeling sleep apnea

Yan Zhu et al.

FRONTIERS IN NEUROLOGY (2015)

Article Neurosciences

Mitochondrial oxidant stress in locus coeruleus is regulated by activity and nitric oxide synthase

Javier Sanchez-Padilla et al.

NATURE NEUROSCIENCE (2014)

Article Multidisciplinary Sciences

A Critical Period of Sleep for Development of Courtship Circuitry and Behavior in Drosophila

Matthew S. Kayser et al.

SCIENCE (2014)

Article Endocrinology & Metabolism

Effects of recovery sleep after one work week of mild sleep restriction on interleukin-6 and cortisol secretion and daytime sleepiness and performance

Slobodanka Pejovic et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2013)

Article Behavioral Sciences

Social and environmental contexts modulate sleep deprivation-induced c-Fos activation in rats

Samuel Deurveilher et al.

BEHAVIOURAL BRAIN RESEARCH (2013)

Article Biochemistry & Molecular Biology

Microglia are the major source of TNF-α and TGF-β1 in postnatal glial cultures; regulation by cytokines, lipopolysaccharide, and vitronectin

Jennifer V. Welser-Alves et al.

NEUROCHEMISTRY INTERNATIONAL (2013)

Article Neurosciences

Synapse Loss Induced by Interleukin-1β Requires Pre- and Post-synaptic Mechanisms

Anjuli Mishra et al.

JOURNAL OF NEUROIMMUNE PHARMACOLOGY (2012)

Review Neurosciences

Synaptic Energy Use and Supply

Julia J. Harris et al.

NEURON (2012)

Article Clinical Neurology

Selective Rapid Eye Movement Sleep Deprivation Affects Cell Size and Number in Kitten Locus Coeruleus

James P. Shaffery et al.

Frontiers in Neurology (2012)

Article Biochemical Research Methods

A new automated method for rat sleep deprivation with minimal confounding effects on corticosterone and locomotor activity

Cathalijn H. C. Leenaars et al.

JOURNAL OF NEUROSCIENCE METHODS (2011)

Article Neurosciences

Locus Ceruleus and Anterior Cingulate Cortex Sustain Wakefulness in a Novel Environment

Heinrich S. Gompf et al.

JOURNAL OF NEUROSCIENCE (2010)

Article Biochemical Research Methods

Validation of a novel method to interrupt sleep in the mouse

Christopher M. Sinton et al.

JOURNAL OF NEUROSCIENCE METHODS (2009)

Article Multidisciplinary Sciences

Amyloid-β Dynamics Are Regulated by Orexin and the Sleep-Wake Cycle

Jae-Eun Kang et al.

SCIENCE (2009)

Review Neurosciences

Purinergic signalling in inflammation of the central nervous system

Francesco Di Virgilio et al.

TRENDS IN NEUROSCIENCES (2009)

Review Neurosciences

Nitric oxide in the central nervous system: neuroprotection versus neurotoxicity

Vittorio Calabrese et al.

NATURE REVIEWS NEUROSCIENCE (2007)

Article Neurosciences

Hippocampal neurogenesis is reduced by sleep fragmentation in the adult rat

R. Guzman-Marin et al.

NEUROSCIENCE (2007)

Article Multidisciplinary Sciences

Sleep deprivation inhibits adult neurogenesis in the hippocampus by elevating glucocorticoids

Christian Mirescu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Neurosciences

REM sleep deprivation inhibits LTP in vivo in area CA1 of rat hippocampus

EY Kim et al.

NEUROSCIENCE LETTERS (2005)

Article Neurosciences

Sleep deprivation suppresses neurogenesis in the adult hippocampus of rats

R Guzman-Marin et al.

EUROPEAN JOURNAL OF NEUROSCIENCE (2005)

Article Neurosciences

Dopamine and noradrenaline control distinct functions in rodent microglial cells

K Färber et al.

MOLECULAR AND CELLULAR NEUROSCIENCE (2005)

Article Biochemistry & Molecular Biology

Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

O Micheau et al.

Article Neurosciences

Sleep deprivation reduces proliferation of cells in the dentate gyrus of the hippocampus in rats

R Guzmán-Marín et al.

JOURNAL OF PHYSIOLOGY-LONDON (2003)

Review Endocrinology & Metabolism

An energy budget for signaling in the grey matter of the brain

D Attwell et al.

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2001)