期刊
TRENDS IN BIOTECHNOLOGY
卷 40, 期 12, 页码 1405-1414出版社
CELL PRESS
DOI: 10.1016/j.tibtech.2022.08.010
关键词
-
资金
- Office of Naval Research [N00014-21-1- 2206]
- US Department of Agriculture [2020-33522-32319]
- US Department of Energy [DE-SC0022003, DE-SC0018324]
- US Environmental Protection Agency [84020501]
- U.S. Department of Energy (DOE) [DE-SC0018324, DE-SC0022003] Funding Source: U.S. Department of Energy (DOE)
This opinion article discusses the future directions and visions of developing microbial consortia as biomanufacturing hosts to address global problems.
The past two decades have witnessed rapid advances in engineering individual microbial strains to produce biochemicals and biomaterials. However, engineering microbial consortia has been relatively slow. Using systems and synthetic biology approaches, researchers have been developing tools for engineering complex microbiota. In this opinion article, I discuss future directions and visions regarding developing microbiota as a biomanufacturing host. Specifically, I propose that we can develop the soil microbial community itself as a huge bioreactor. Ultimately, researchers will provide a generalizable system that enables us to understand a microbial consortium's interaction and metabolism on diverse temporal and spatial scales to address global problems, including the climate crisis, food inequality, the issue of waste, and sustainable bioproduction.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据