4.6 Article

Performance of QuantiFERON-TB Gold Plus assays in paediatric tuberculosis: a multicentre PTBNET study

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Summary: In a cross-sectional study of 284 children and adolescents suspected of tuberculosis in a low-endemic country, the QuantiFERON-TB Gold Plus assay showed a specificity of 91.5%, sensitivity of 87.3%, positive predictive value of 86.4%, and negative predictive value of 91.2%, performing better than tuberculin skin tests but similar to previous-generation interferon-gamma release assays.

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