Small and large intestinal cancer in patients with Crohn's disease studied by surgeons

Purpose The current study summarized the clinical course and treatment outcomes of intestinal cancer in CD seen in our department and explored the steps to take in the future. Methods Subjects were patients who had been diagnosed with CD at our hospital and who underwent surgery in our department from 1985 to 2020. Results Thirty-one patients had CD and intestinal cancer, including 6 with cancer of the small intestine and 25 with cancer of the large intestine. In all six patients with cancer of the small intestine, the site where cancer or a tumor developed was at or near the site of the anastomosis made at a previous surgery. Of the 25 patients with cancer of the large intestine, 22 developed cancer in the rectum or anal region. Conclusion Many of the patients with cancer of the small intestine had previously undergone surgery, and the cancer developed at or near the site of the anastomosis. In patients who have previously undergone resection of the small intestine, the small intestine needs to be examined regularly. Cancer of the large intestine often developed in the rectum or anal region of our patients, so a detailed examination of the same site needs to be performed.

Automated summary

The current study summarized the clinical course and treatment outcomes of intestinal cancer in CD patients in our department and highlighted the importance of regular examination of the small intestine and detailed examination of the rectum or anal region during treatment.