4.1 Editorial Material

Current Evidence Demonstrates That Monkeypox Is a Sexually Transmitted Infection

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Article Infectious Diseases

Clinical features and management of human monkeypox: a retrospective observational study in the UK

Hugh Adler et al.

Summary: This study retrospectively observed the clinical course of monkeypox in seven patients in the UK from 2018 to 2021. The study found that prolonged PCR positivity led to isolation of five patients for more than 3 weeks. Three patients treated with brincidofovir developed elevated liver enzymes, leading to termination of the therapy. One patient treated with tecovirimat experienced no adverse effects and had a shorter duration of viral shedding and illness compared to the other six patients.

LANCET INFECTIOUS DISEASES (2022)

Article Medicine, General & Internal

Clinical presentation and virological assessment of confirmed human monkeypox virus cases in Spain: a prospective observational cohort study

Eloy Jose Tarin-Vicente et al.

Summary: This study investigated the clinical and virological characteristics of cases of human monkeypox in Spain. The findings showed that monkeypox caused genital, perianal, and oral lesions and complications including proctitis and tonsillitis. Lesion swabs showed the highest viral loads, suggesting close contact as the dominant transmission route in the current outbreak.

LANCET (2022)

Article Infectious Diseases

Demographic and clinical characteristics of confirmed human monkeypox virus cases in individuals attending a sexual health centre in London, UK: an observational analysis

Nicolo Girometti et al.

Summary: Autochthonous community monkeypox virus transmission is currently observed among MSM in the UK. High proportion of concomitant STIs and frequent anogenital symptoms suggest transmissibility through local inoculation during close skin-to-skin or mucosal contact, during sexual activity. Additional resources are needed to support sexual health and other specialist services in managing this condition. A review of the case definition and better understanding of viral transmission routes are necessary for the development of infection control policies, education and prevention strategies, and contact tracing.

LANCET INFECTIOUS DISEASES (2022)

Editorial Material Medicine, General & Internal

Monkeypox Genital Lesions

Rita Patrocinio-Jesus et al.

Summary: This is a case of genital lesions caused by monkeypox. The patient presented with genital rash, lymphadenopathy, and ulcers.

NEW ENGLAND JOURNAL OF MEDICINE (2022)

Article Medicine, General & Internal

Monkeypox Virus Infection in Humans across 16 Countries - April-June 2022

John P. Thornhill et al.

Summary: This report describes 528 cases of monkeypox in 16 countries. Common clinical findings include rash, mucosal lesions, fever, lethargy, and lymphadenopathy. Few patients required hospitalization.

NEW ENGLAND JOURNAL OF MEDICINE (2022)

Article Public, Environmental & Occupational Health

Epidemiologic and Clinical Characteristics of Monkeypox Cases — United States, May 17–July 22, 2022

David Philpott et al.

MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT (2022)

Review Immunology

Monkeypox: A Contemporary Review for Healthcare Professionals

Boghuma K. Titanji et al.

Summary: Monkeypox is an emerging zoonotic disease of global health concern that has significant epidemic potential. Healthcare professionals worldwide should familiarize themselves with the clinical presentations and management of this viral infection, especially in light of ongoing outbreaks.

OPEN FORUM INFECTIOUS DISEASES (2022)

Article Infectious Diseases

Demographic and clinical characteristics of confirmed human monkeypox virus cases in individuals attending a sexual health centre in London, UK: an observational analysis

Nicole Girometti et al.

Summary: In the UK, monkeypox virus infection is increasingly observed among men who have sex with men, presenting with symptoms such as fatigue, fever, and skin lesions mainly in anogenital areas. Concurrent sexually transmitted infections are common, and there is a need for improved infection control policies and prevention strategies to address this emerging public health concern.

LANCET INFECTIOUS DISEASES (2022)

Article Infectious Diseases

Outbreak of human monkeypox in Nigeria in 2017-18: a clinical and epidemiological report

Adesola Yinka-Ogunleye et al.

LANCET INFECTIOUS DISEASES (2019)

Review Dermatology

Molluscum contagiosum: an update and review of new perspectives in etiology, diagnosis, and treatment

Rodrigo Meza-Romero et al.

CLINICAL COSMETIC AND INVESTIGATIONAL DERMATOLOGY (2019)

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Anti-homosexual legislation and HIV-related stigma in African nations: what has been the role of PEPFAR?

Amy Hagopian et al.

GLOBAL HEALTH ACTION (2017)

Review Public, Environmental & Occupational Health

Syphilis transmission: a review of the current evidence

Juliet E. Stoltey et al.

SEXUAL HEALTH (2015)

Article Infectious Diseases

Acquired Macrolide-Resistant Treponema pallidum After a Human Bite

Robyn Neblett Fanfair et al.

SEXUALLY TRANSMITTED DISEASES (2014)

Article Medicine, General & Internal

Successes and challenges of HIV prevention in men who have sex with men

Patrick S. Sullivan et al.

LANCET (2012)

Article Public, Environmental & Occupational Health

Relationships of stigma and shame to gonorrhea and HIV screening

JD Fortenberry et al.

AMERICAN JOURNAL OF PUBLIC HEALTH (2002)