相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Therapy-induced mutations drive the genomic landscape of relapsed acute lymphoblastic leukemia
Benshang Li et al.
BLOOD (2020)
Decitabine and Vorinostat with Chemotherapy in Relapsed Pediatric Acute Lymphoblastic Leukemia: A TACL Pilot Study
Michael J. Burke et al.
CLINICAL CANCER RESEARCH (2020)
Glucocorticoids paradoxically facilitate steroid resistance in T cell acute lymphoblastic leukemias and thymocytes
Lauren K. Meyer et al.
JOURNAL OF CLINICAL INVESTIGATION (2020)
Effect of Dasatinib vs Imatinib in the Treatment of Pediatric Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia A Randomized Clinical Trial
Shuhong Shen et al.
JAMA ONCOLOGY (2020)
IKZF1 alterations in acute lymphoblastic leukemia: The good, the bad and the ugly
Stephanie Vairy et al.
BLOOD REVIEWS (2020)
Novel Multiplex Droplet Digital PCR Assays to Monitor Minimal Residual Disease in Chronic Myeloid Leukemia Patients Showing Atypical BCR-ABL1 Transcripts
Jessica Petiti et al.
JOURNAL OF CLINICAL MEDICINE (2020)
HLA alleles associated with asparaginase hypersensitivity in childhood ALL: a report from the DFCI Consortium
Vincent Gagne et al.
PHARMACOGENOMICS (2020)
Detection of Fusion Genes to Determine Minimal Residual Disease in Leukemia Using Next-Generation Sequencing
Eddy N. de Boer et al.
CLINICAL CHEMISTRY (2020)
Novel inhibitors of the histone methyltransferase DOT1L show potent antileukemic activity in patient-derived xenografts
Florian Perner et al.
BLOOD (2020)
Cranial Radiation Can be Eliminated in Most Children with T-Cell Acute Lymphoblastic Leukemia (T-ALL) and Bortezomib Potentially Improves Survival in Children with T-Cell Lymphoblastic Lymphoma (T-LL): Results of Children's Oncology Group (COG) Trial AALL1231
David T. Teachey et al.
BLOOD (2020)
Clinical response to larotrectinib in adult Philadelphia chromosome-like ALL with cryptic ETV6-NTRK3 rearrangement
Valentina Nardi et al.
BLOOD ADVANCES (2020)
Minimal residual disease in acute lymphoblastic leukemia: technical aspects and implications for clinical interpretation
In-Suk Kim
BLOOD RESEARCH (2020)
Unraveling the cellular origin and clinical prognostic markers of infant B-cell acute lymphoblastic leukemia using genome-wide analysis
Antonio Agraz-Doblas et al.
HAEMATOLOGICA (2019)
Comparative features and outcomes between paediatric T-cell and B-cell acute lymphoblastic leukaemia
David T. Teachey et al.
LANCET ONCOLOGY (2019)
Prognostic factors for survival after relapsed acute lymphoblastic leukemia (ALL): A Children's Oncology Group (COG) study.
Susan R. Rheingold et al.
JOURNAL OF CLINICAL ONCOLOGY (2019)
Genome-Wide Association Study of Susceptibility Loci for T-Cell Acute Lymphoblastic Leukemia in Children
Maoxiang Qian et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2019)
Inherited genetic susceptibility to acute lymphoblastic leukemia in Down syndrome
Austin L. Brown et al.
BLOOD (2019)
Genetic defects in hematopoietic transcription factors and predisposition to acute lymphoblastic leukemia
Yoshihiro Gocho et al.
BLOOD (2019)
Outcome of Infants Younger Than 1 Year With Acute Lymphoblastic Leukemia Treated With the Interfant-06 Protocol: Results From an International Phase III Randomized Study
Rob Pieters et al.
JOURNAL OF CLINICAL ONCOLOGY (2019)
Efficacy of tyrosine kinase inhibitors in Ph-like acute lymphoblastic leukemia harboring ABL-class rearrangements
Ilaria Tanasi et al.
BLOOD (2019)
Safety, Efficacy, and PK of the BCL2 Inhibitor Venetoclax in Combination with Chemotherapy in Pediatric and Young Adult Patients with Relapsed/Refractory Acute Myeloid Leukemia and Acute Lymphoblastic Leukemia: Phase 1 Study
Seth E. Karol et al.
BLOOD (2019)
Genes identified through genome-wide association studies of osteonecrosis in childhood acute lymphoblastic leukemia patients
Vincent Gagne et al.
PHARMACOGENOMICS (2019)
A pediatric regimen for older adolescents and young adults with acute lymphoblastic leukemia: results of CALGB 10403
Wendy Stock et al.
BLOOD (2019)
How advanced are we in targeting novel subtypes of ALL?
Charles G. Mullighan
BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY (2019)
A Phase 2 Trial of Inotuzumab Ozogamicin (InO) in Children and Young Adults with Relapsed or Refractory (R/R) CD22+B-Acute Lymphoblastic Leukemia (B-ALL): Results from Children's Oncology Group Protocol AALL1621
Maureen M. O'Brien et al.
BLOOD (2019)
A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia
Andrei V. Krivtsov et al.
CANCER CELL (2019)
Genomic landscape of pediatric B-other acute lymphoblastic leukemia in a consecutive European cohort
Marketa Zaliova et al.
HAEMATOLOGICA (2019)
PAX5-driven subtypes of B-progenitor acute lymphoblastic leukemia
Zhaohui Gu et al.
NATURE GENETICS (2019)
Preclinical efficacy of daratumumab in T-cell acute lymphoblastic leukemia
Karen L. Bride et al.
BLOOD (2018)
The DOT1L inhibitor pinometostat reduces H3K79 methylation and has modest clinical activity in adult acute leukemia
Eytan M. Stein et al.
BLOOD (2018)
Germline Genetic IKZF1 Variation and Predisposition to Childhood Acute Lymphoblastic Leukemia
Michelle L. Churchman et al.
CANCER CELL (2018)
Clinical efficacy of ruxolitinib and chemotherapy in a child with Philadelphia chromosome-like acute lymphoblastic leukemia with GOLGA5-JAK2 fusion and induction failure
Yang Y. Ding et al.
HAEMATOLOGICA (2018)
Dasatinib Plus Intensive Chemotherapy in Children, Adolescents, and Young Adults With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia: Results of Children's Oncology Group Trial AALL0622
William B. Slayton et al.
JOURNAL OF CLINICAL ONCOLOGY (2018)
Clonal evolution mechanisms in NT5C2 mutant/relapsed acute lymphoblastic leukaemia
Gannie Tzoneva et al.
NATURE (2018)
Phase I trial of the mTOR inhibitor everolimus in combination with multi-agent chemotherapy in relapsed childhood acute lymphoblastic leukemia
Andrew E. Place et al.
PEDIATRIC BLOOD & CANCER (2018)
Clinical efficacy of ruxolitinib and chemotherapy in a child with Philadelphia chromosome-like acute lymphoblastic leukemia with GOLGA5-JAK2 fusion and induction failure
Yang Y. Ding et al.
HAEMATOLOGICA (2018)
Transcriptional landscape of B cell precursor acute lymphoblastic leukemia based on an international study of 1,223 cases
Jian-Feng Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Imatinib treatment of paediatric Philadelphia chromosome-positive acute lymphoblastic leukaemia (EsPhALL2010): a prospective, intergroup, open-label, single-arm clinical trial
Andrea Biondi et al.
LANCET HAEMATOLOGY (2018)
Measurable residual disease detection by high-throughput sequencing improves risk stratification for pediatric B-ALL
Brent Wood et al.
BLOOD (2018)
Genomic characterization of paediatric acute lymphoblastic leukaemia: an opportunity for precision medicine therapeutics
Sarah K. Tasian et al.
BRITISH JOURNAL OF HAEMATOLOGY (2017)
An Inherited Genetic Variant in CEP72 Promoter Predisposes to Vincristine-Induced Peripheral Neuropathy in Adults With Acute Lymphoblastic Leukemia
W. Stock et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2017)
HLA-DRB1*07:01-HLA-DQA1*02:01-HLADQB1*02:02 haplotype is associated with a high risk of asparaginase hypersensitivity in acute lymphoblastic leukemia
Nora Kutszegi et al.
HAEMATOLOGICA (2017)
The genomic landscape of pediatric and young adult T-lineage acute lymphoblastic leukemia
Yu Liu et al.
NATURE GENETICS (2017)
HLA-DRB1*07:01-HLA-DQA1*02:01-HLADQB1*02:02 haplotype is associated with a high risk of asparaginase hypersensitivity in acute lymphoblastic leukemia
Nora Kutszegi et al.
HAEMATOLOGICA (2017)
Philadelphia chromosome-like acute lymphoblastic leukemia
Sarah K. Tasian et al.
BLOOD (2017)
A phase 1 trial of temsirolimus and intensive re-induction chemotherapy for 2nd or greater relapse of acute lymphoblastic leukaemia: a Children's Oncology Group study (ADVL1114)
Susan R. Rheingold et al.
BRITISH JOURNAL OF HAEMATOLOGY (2017)
Venetoclax responses of pediatric ALL xenografts reveal sensitivity of MLL-rearranged leukemia
Seong Lin Khaw et al.
BLOOD (2016)
Acute lymphoblastic leukemia and lymphoma in the context of constitutional mismatch repair deficiency syndrome
Tim Ripperger et al.
EUROPEAN JOURNAL OF MEDICAL GENETICS (2016)
Clinical and Genetic Risk Factors for Acute Pancreatitis in Patients With Acute Lymphoblastic Leukemia
Chengcheng Liu et al.
JOURNAL OF CLINICAL ONCOLOGY (2016)
Deregulation of DUX4 and ERG in acute lymphoblastic leukemia
Jinghui Zhang et al.
NATURE GENETICS (2016)
Identification of ETV6-RUNX1-like and DUX4-rearranged subtypes in paediatric B-cell precursor acute lymphoblastic leukaemia
Henrik Lilljebjorn et al.
NATURE COMMUNICATIONS (2016)
Genomic analyses identify recurrent MEF2D fusions in acute lymphoblastic leukaemia
Zhaohui Gu et al.
NATURE COMMUNICATIONS (2016)
Ph-like acute lymphoblastic leukemia
Thai Hoa Tran et al.
HEMATOLOGY-AMERICAN SOCIETY OF HEMATOLOGY EDUCATION PROGRAM (2016)
Prognostic significance of minimal residual disease in high risk B-ALL: a report from Children's Oncology Group study AALL0232
Michael J. Borowitz et al.
BLOOD (2015)
Efficacy of JAK/STAT pathway inhibition in murine xenograft models of early T-cell precursor (ETP) acute lymphoblastic leukemia
Shannon L. Maude et al.
BLOOD (2015)
Inherited genetic variation in childhood acute lymphoblastic leukemia
Takaya Moriyama et al.
BLOOD (2015)
Efficacy of Retinoids in IKZF1-Mutated BCR-ABL1 Acute Lymphoblastic Leukemia
Michelle L. Churchman et al.
CANCER CELL (2015)
Pharmacologic Inhibition of the Menin-MLL Interaction Blocks Progression of MLL Leukemia In Vivo
Dmitry Borkin et al.
CANCER CELL (2015)
BCR-ABL1-like cases in pediatric acute lymphoblastic leukemia: a comparison between DCOG/Erasmus MC and COG/St. Jude signatures
Judith M. Boer et al.
HAEMATOLOGICA (2015)
Association of an Inherited Genetic Variant With Vincristine-Related Peripheral Neuropathy in Children With Acute Lymphoblastic Leukemia
Barthelemy Diouf et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2015)
Inherited NUDT15 Variant Is a Genetic Determinant of Mercaptopurine Intolerance in Children With Acute Lymphoblastic Leukemia
Jun J. Yang et al.
JOURNAL OF CLINICAL ONCOLOGY (2015)
Childhood Acute Lymphoblastic Leukemia: Progress Through Collaboration
Ching-Hon Pui et al.
JOURNAL OF CLINICAL ONCOLOGY (2015)
Germ line ETV6 mutations in familial thrombocytopenia and hematologic malignancy
Michael Y. Zhang et al.
NATURE GENETICS (2015)
The landscape of somatic mutations in infant MLL-rearranged acute lymphoblastic leukemias
Anna K. Andersson et al.
NATURE GENETICS (2015)
Negative feedback-defective PRPS1 mutants drive thiopurine resistance in relapsed childhood ALL
Benshang Li et al.
NATURE MEDICINE (2015)
Acute Lymphoblastic Leukemia in Children
Stephen P. Hunger et al.
NEW ENGLAND JOURNAL OF MEDICINE (2015)
Rise and fall of subclones from diagnosis to relapse in pediatric B-acute lymphoblastic leukaemia
Xiaotu Ma et al.
NATURE COMMUNICATIONS (2015)
MLL-Rearranged Acute Lymphoblastic Leukemias Activate BCL-2 through H3K79 Methylation and Are Sensitive to the BCL-2-Specific Antagonist ABT-199
Juliana M. Benito et al.
CELL REPORTS (2015)
BCR-ABL1-like cases in pediatric acute lymphoblastic leukemia: a comparison between DCOG/Erasmus MC and COG/St. Jude signatures
Judith M. Boer et al.
HAEMATOLOGICA (2015)
Acute lymphoblastic leukemia in children with Down syndrome: a retrospective analysis from the Ponte di Legno study group
Trudy D. Buitenkamp et al.
BLOOD (2014)
HLA-DRB1*07:01 is associated with a higher risk of asparaginase allergies
Christian A. Fernandez et al.
BLOOD (2014)
Ras pathway mutations are prevalent in relapsed childhood acute lymphoblastic leukemia and confer sensitivity to MEK inhibition
Julie Irving et al.
BLOOD (2014)
Declining Childhood and Adolescent Cancer Mortality
Malcolm A. Smith et al.
CANCER (2014)
Outcomes of Children With BCR-ABL1-Like Acute Lymphoblastic Leukemia Treated With Risk-Directed Therapy Based on the Levels of Minimal Residual Disease
Kathryn G. Roberts et al.
JOURNAL OF CLINICAL ONCOLOGY (2014)
Long-term follow-up of imatinib in pediatric Philadelphia chromosome-positive acute lymphoblastic leukemia: Children's Oncology Group Study AALL0031
K. R. Schultz et al.
LEUKEMIA (2014)
Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia
Shannon L. Maude et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
Targetable Kinase-Activating Lesions in Ph-like Acute Lymphoblastic Leukemia
K. G. Roberts et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
Targeting the PI3K/mTOR pathway hematologic malignancies
Sarah K. Tasian et al.
FRONTIERS IN ONCOLOGY (2014)
Tyrosine kinome sequencing of pediatric acute lymphoblastic leukemia: a report from the Children's Oncology Group TARGET Project
Mignon L. Loh et al.
BLOOD (2013)
Potent inhibition of DOT1L as treatment of MLL-fusion leukemia
Scott R. Daigle et al.
BLOOD (2013)
Proteasome inhibitors in acute leukemia
Denise Niewerth et al.
EXPERT REVIEW OF ANTICANCER THERAPY (2013)
Re: Novel Susceptibility Variants at 10p12.31-12.2 for Childhood Acute Lymphoblastic Leukemia in Ethnically Diverse Populations Response
Virginia Perez-Andreu et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2013)
Novel Susceptibility Variants at 10p12.31-12.2 for Childhood Acute Lymphoblastic Leukemia in Ethnically Diverse Populations
Heng Xu et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2013)
The genomic landscape of hypodiploid acute lymphoblastic leukemia
Linda Holmfeldt et al.
NATURE GENETICS (2013)
A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia
Sohela Shah et al.
NATURE GENETICS (2013)
Relapse-specific mutations in NT5C2 in childhood acute lymphoblastic leukemia
Julia A. Meyer et al.
NATURE GENETICS (2013)
Inherited GATA3 variants are associated with Ph-like childhood acute lymphoblastic leukemia and risk of relapse
Virginia Perez-Andreu et al.
NATURE GENETICS (2013)
Treatment of infant leukemias: challenge and promise
Patrick Brown
HEMATOLOGY-AMERICAN SOCIETY OF HEMATOLOGY EDUCATION PROGRAM (2013)
Aberrant STAT5 and PI3K/mTOR pathway signaling occurs in human CRLF2-rearranged B-precursor acute lymphoblastic leukemia
Sarah K. Tasian et al.
BLOOD (2012)
Epigenetic reprogramming reverses the relapse-specific gene expression signature and restores chemosensitivity in childhood B-lymphoblastic leukemia
Teena Bhatla et al.
BLOOD (2012)
Targeting JAK1/2 and mTOR in murine xenograft models of Ph-like acute lymphoblastic leukemia
Shannon L. Maude et al.
BLOOD (2012)
Genetic Alterations Activating Kinase and Cytokine Receptor Signaling in High-Risk Acute Lymphoblastic Leukemia
Kathryn G. Roberts et al.
CANCER CELL (2012)
Rare versus common variants in pharmacogenetics: SLCO1B1 variation and methotrexate disposition
Laura B. Ramsey et al.
GENOME RESEARCH (2012)
ARID5B Genetic Polymorphisms Contribute to Racial Disparities in the Incidence and Treatment Outcome of Childhood Acute Lymphoblastic Leukemia
Heng Xu et al.
JOURNAL OF CLINICAL ONCOLOGY (2012)
Anthracycline-Related Cardiomyopathy After Childhood Cancer: Role of Polymorphisms in Carbonyl Reductase Genes-A Report From the Children's Oncology Group
Javier G. Blanco et al.
JOURNAL OF CLINICAL ONCOLOGY (2012)
Imatinib after induction for treatment of children and adolescents with Philadelphia-chromosome-positive acute lymphoblastic leukaemia (EsPhALL): a randomised, open-label, intergroup study
Andrea Biondi et al.
LANCET ONCOLOGY (2012)
Connectivity mapping identifies HDAC inhibitors for the treatment of t(4;11)-positive infant acute lymphoblastic leukemia
D. J. P. M. Stumpel et al.
LEUKEMIA (2012)
The genetic basis of early T-cell precursor acute lymphoblastic leukaemia
Jinghui Zhang et al.
NATURE (2012)
MLL-Rearranged Leukemia Is Dependent on Aberrant H3K79 Methylation by DOT1L
Kathrin M. Bernt et al.
CANCER CELL (2011)
CREBBP mutations in relapsed acute lymphoblastic leukaemia
Charles G. Mullighan et al.
NATURE (2011)
Down syndrome childhood acute lymphoblastic leukemia has a unique spectrum of sentinel cytogenetic lesions that influences treatment outcome: a report from the Children's Oncology Group
Kelly W. Maloney et al.
BLOOD (2010)
Molecular response to treatment redefines all prognostic factors in children and adolescents with B-cell precursor acute lymphoblastic leukemia: results in 3184 patients of the AIEOP-BFM ALL 2000 study
Valentino Conter et al.
BLOOD (2010)
Promoter hypermethylation in MLL-r infant acute lymphoblastic leukemia: biology and therapeutic targeting
Eric Schafer et al.
BLOOD (2010)
Clinical Outcome of Children With Newly Diagnosed Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia Treated Between 1995 and 2005
Maurizio Arico et al.
JOURNAL OF CLINICAL ONCOLOGY (2010)
Outcomes for Children and Adolescents With Cancer: Challenges for the Twenty-First Century
Malcolm A. Smith et al.
JOURNAL OF CLINICAL ONCOLOGY (2010)
Variation in CDKN2A at 9p21.3 influences childhood acute lymphoblastic leukemia risk
Amy L. Sherborne et al.
NATURE GENETICS (2010)
Specific promoter methylation identifies different subgroups of MLL-rearranged infant acute lymphoblastic leukemia, influences clinical outcome, and provides therapeutic options
Dominique J. P. M. Stumpel et al.
BLOOD (2009)
Potentiating effects of RAD001 (Everolimus) on vincristine therapy in childhood acute lymphoblastic leukemia
Roman Crazzolara et al.
BLOOD (2009)
Improved Early Event-Free Survival With Imatinib in Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia: A Children's Oncology Group Study
Kirk R. Schultz et al.
JOURNAL OF CLINICAL ONCOLOGY (2009)
A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: a genome-wide classification study
Monique L. Den Boer et al.
LANCET ONCOLOGY (2009)
Rearrangement of CRLF2 in B-progenitor- and Down syndrome-associated acute lymphoblastic leukemia
Charles G. Mullighan et al.
NATURE GENETICS (2009)
Germline genomic variants associated with childhood acute lymphoblastic leukemia
Lisa R. Trevino et al.
NATURE GENETICS (2009)
Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia
Elli Papaemmanuil et al.
NATURE GENETICS (2009)
Deletion of IKZF1 and Prognosis in Acute Lymphoblastic Leukemia.
Charles G. Mullighan et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia and its relationship to other prognostic factors: a Children's Oncology Group study
Michael J. Borowitz et al.
BLOOD (2008)
Menin critically links MLL proteins with LEDGE on cancer-associated target genes
Akihiko Yokoyama et al.
CANCER CELL (2008)
A treatment protocol for infants younger than 1 year with acute lymphoblastic leukaemia (Interfant-99): an observational study and a multicentre randomised trial
Rob Pieters et al.
LANCET (2007)
Combined effects of the two reciprocal t(4; II) fusion proteins MLL . AF4 and AF4 . MLL confer resistance to apoptosis, cell cycling capacity and growth transformation
A. Gaussmann et al.
ONCOGENE (2007)
Down syndrome and acute lymphoblastic leukaemia
James A. Whitlock
BRITISH JOURNAL OF HAEMATOLOGY (2006)
Resistance of infant leukemia with MLL rearrangement to tumor necrosis factor-related apoptosis-inducing ligand:: a possible mechanism for poor sensitivity to antitumor immunity
T. Inukai et al.
LEUKEMIA (2006)
Analysis of prognostic factors of acute lymphoblastic leukemia in infants: report on CCG 1953 from the Children's Oncology Group
Joanne M. Hilden et al.
BLOOD (2006)
FLT3 inhibition selectively kills childhood acute lymphoblastic leukemia cells with high levels of FLT3 expression
P Brown et al.
BLOOD (2005)
Standardization and quality control studies of 'real-time' quantitative reverse transcriptase polymerase chain reaction of fusion gene transcripts for residual disease detection in leukemia -: A Europe Against Cancer Program
J Gabert et al.
LEUKEMIA (2003)
Prognostic significance and modalities of flow cytometric minimal residual disease detection in childhood acute lymphoblastic leukemia
MN Dworzak et al.
BLOOD (2002)
Clinical importance of minimal residual disease in childhood acute lymphoblastic leukemia
E Coustan-Smith et al.
BLOOD (2000)
分享论文
