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Translating diagnostics and drug delivery technologies to low-resource settings

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SCIENCE TRANSLATIONAL MEDICINE
卷 14, 期 666, 页码 -

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AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/scitranslmed.abm1732

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  1. National Institutes of Health [R03EB031495, K22AI146215]

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This article discusses the clinical success factors for diagnostics and drug delivery systems in low-resource settings and provides recommendations for the clinical translation of future medical technologies.
Diagnostics and drug delivery technologies engineered for low-resource settings aim to meet their technical design specifications using strategies that are compatible with limited equipment, infrastructure, and operator training. Despite many preclinical successes, very few of these devices have been translated to the clinic. Here, we identify factors that contribute to the clinical success of diagnostics and drug delivery systems for low-resource settings, including the need to engage key stakeholders at an early stage, and provide recommendations for the clinical translation of future medical technologies.

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