4.6 Article

Defects of microtubule cytoskeletal organization in NOA human testes

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

Human obstructive (postvasectomy) and nonobstructive azoospermia - Insights from scRNA-Seq and transcriptome analysis

Shitao Chen et al.

Summary: By analyzing testis biopsy samples using single-cell RNA sequencing, this study revealed transcriptional changes in Sertoli cells in response to a loss of interactions with germ cells in patients with obstructive azoospermia and nonobstructive azoospermia. Additionally, a discrepancy in germ cell populations was observed between an obstructive azoospermia patient and a healthy individual.

GENES & DISEASES (2022)

Article Endocrinology & Metabolism

KIF15 supports spermatogenesis via its effects on Sertoli cell microtubule, actin, vimentin, and septin cytoskeletons

Siwen Wu et al.

Summary: This study investigated the role of MT-dependent and microtubule plus end-directed motor protein kinesin 15 (KIF15) in the testis. KIF15 showed stage-specific expression and association with MTs in the seminiferous epithelium, playing a crucial role in supporting spermatid transport. Knockdown of KIF15 in Sertoli cells disrupted the barrier function and cytoskeletal organization, indicating that KIF15 regulates cellular functions beyond microtubules.

ENDOCRINOLOGY (2021)

Review Medicine, General & Internal

Differential Diagnosis of Azoospermia in Men with Infertility

Danilo L. Andrade et al.

Summary: The differential diagnosis between obstructive and nonobstructive azoospermia involves a comprehensive evaluation including medical history, physical examination, semen analysis, hormonal assessment, genetic tests, and imaging studies. Testicular biopsy may be necessary in cases of doubt, and should be combined with sperm extraction for sperm cryopreservation. A multidisciplinary approach involving reproductive urologists/andrologists, geneticists, pathologists, and embryologists is crucial for the best diagnostic path for men with azoospermia.

JOURNAL OF CLINICAL MEDICINE (2021)

Article Urology & Nephrology

Transcriptome Analysis to Identify Human Spermatogonial Cells from Sertoli Cell-Only Testes

Koji Shiraishi et al.

JOURNAL OF UROLOGY (2020)

Article Cell & Tissue Engineering

The Dynamic Transcriptional Cell Atlas of Testis Development during Human Puberty

Jingtao Guo et al.

CELL STEM CELL (2020)

Review Toxicology

Microtubule Cytoskeleton and Spermatogenesis-Lesson From Studies of Toxicant Models

Lingling Wang et al.

TOXICOLOGICAL SCIENCES (2020)

Review Biochemistry & Molecular Biology

Seminal Plasma Transcriptome and Proteome: Towards a Molecular Approach in the Diagnosis of Idiopathic Male Infertility

Rossella Cannarella et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Article Reproductive Biology

Actin binding proteins, actin cytoskeleton and spermatogenesis - Lesson from toxicant models

Lingling Wang et al.

REPRODUCTIVE TOXICOLOGY (2020)

Article Multidisciplinary Sciences

Single-cell analysis of developing and azoospermia human testicles reveals central role of Sertoli cells

LiangYu Zhao et al.

NATURE COMMUNICATIONS (2020)

Article Biochemistry & Molecular Biology

Identification of Premeiotic, Meiotic, and Postmeiotic Cells in Testicular Biopsies Without Sperm from Sertoli Cell-Only Syndrome Patients

Maram Abofoul-Azab et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Review Developmental Biology

The cytoskeleton in spermatogenesis

Jessica E. M. Dunleavy et al.

REPRODUCTION (2019)

Review Cell Biology

Microtubule-Asssociated Proteins: Structuring the Cytoskeleton

Satish Bodakuntla et al.

TRENDS IN CELL BIOLOGY (2019)

Article Endocrinology & Metabolism

mTORC1/rpS6 regulates blood-testis barrier dynamics and spermatogenetic function in the testis in vivo

Stephen Y. T. Li et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2018)

Article Endocrinology & Metabolism

Dynein 1 supports spermatid transport and spermiation during spermatogenesis in the rat testis

Qing Wen et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2018)

Article Biotechnology & Applied Microbiology

Integrating single-cell transcriptomic data across different conditions, technologies, and species

Andrew Butler et al.

NATURE BIOTECHNOLOGY (2018)

Editorial Material Anatomy & Morphology

An Introduction to Actin Actin-Rich Structures

A. Wayne Vogl et al.

ANATOMICAL RECORD-ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY (2018)

Article Cell Biology

The adult human testis transcriptional cell atlas

Jingtao Guo et al.

CELL RESEARCH (2018)

Article Andrology

Expression of hOvol2 in the XY body of human spermatocytes

H. Taniguchi et al.

ANDROLOGIA (2017)

Article Endocrinology & Metabolism

Concepts in diagnosis and therapy for male reproductive impairment

Herman Tournaye et al.

LANCET DIABETES & ENDOCRINOLOGY (2017)

Article Endocrinology & Metabolism

Novel concepts in the aetiology of male reproductive impairment

Herman Tournaye et al.

LANCET DIABETES & ENDOCRINOLOGY (2017)

Article Obstetrics & Gynecology

Genetic diagnostics of male infertility in clinical practice

Ryan Flannigan et al.

BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY (2017)

Review Cell Biology

Regulation of microtubule (MT)-based cytoskeleton in the seminiferous epithelium during spermatogenesis

Elizabeth I. Tang et al.

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2016)

Review Biochemistry & Molecular Biology

How Dynein Moves Along Microtubules

Gira Bhabha et al.

TRENDS IN BIOCHEMICAL SCIENCES (2016)

Review Andrology

Clinical management of infertile men with nonobstructive azoospermia

Sandro C. Esteves

ASIAN JOURNAL OF ANDROLOGY (2015)

Editorial Material Urology & Nephrology

CUA Guideline: The workup and management of azoospermic males

Keith Jarvi et al.

CUAJ-CANADIAN UROLOGICAL ASSOCIATION JOURNAL (2015)

Article Biotechnology & Applied Microbiology

Spatial reconstruction of single-cell gene expression data

Rahul Satija et al.

NATURE BIOTECHNOLOGY (2015)

Review Cell Biology

Control of microtubule organization and dynamics: two ends in the limelight

Anna Akhmanova et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2015)

Article Multidisciplinary Sciences

Periodic retinoic acid-STRA8 signaling intersects with periodic germ-cell competencies to regulate spermatogenesis

Tsutomu Endo et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Article Endocrinology & Metabolism

Peritubular Myoid Cells Participate in Male Mouse Spermatogonial Stem Cell Maintenance

Liang-Yu Chen et al.

ENDOCRINOLOGY (2014)

Review Cell Biology

Microtubules and spermatogenesis

Liza O'Donnell et al.

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2014)

Review Cell Biology

Novel clathrin/actin-based endocytic machinery associated with junction turnover in the seminiferous epithelium

A. Wayne Vogl et al.

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2014)

Article Reproductive Biology

Novel Stage Classification of Human Spermatogenesis Based on Acrosome Development

Barbara Muciaccia et al.

BIOLOGY OF REPRODUCTION (2013)

Review Medicine, General & Internal

Medical management of non-obstructive azoospermia

Rajeev Kumar

CLINICS (2013)

Review Endocrinology & Metabolism

MAP/microtubule affinity-regulating kinases, microtubule dynamics, and spermatogenesis

Elizabeth I. Tang et al.

JOURNAL OF ENDOCRINOLOGY (2013)

Review Immunology

Phenotypic and functional heterogeneity of the testicular macrophage population: a new regulatory model

Wendy R. Winnall et al.

JOURNAL OF REPRODUCTIVE IMMUNOLOGY (2013)

Review Andrology

Mouse models in male fertility research

Duangporn Jamsai et al.

ASIAN JOURNAL OF ANDROLOGY (2011)

Editorial Material Urology & Nephrology

CUA Guideline: The workup of azoospermic males

Keith Jarvi et al.

CUAJ-CANADIAN UROLOGICAL ASSOCIATION JOURNAL (2010)

Review Cell Biology

Kinesin superfamily motor proteins and intracellular transport

Nobutaka Hirokawa et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2009)

Review Cell Biology

Tracking the ends: a dynamic protein network controls the fate of microtubule tips

Anna Akhmanova et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)

Review Obstetrics & Gynecology

Which is the best sperm retrieval technique for non-obstructive azoospermia? A systematic review

P. Donoso et al.

HUMAN REPRODUCTION UPDATE (2007)

Article Urology & Nephrology

The role of testicular biopsy in the modern management of male infertility

RA Schoor et al.

JOURNAL OF UROLOGY (2002)

Review Cell Biology

Unique and multifunctional adhesion junctions in the testis: Ectoplasmic specializations

AW Vogl et al.

ARCHIVES OF HISTOLOGY AND CYTOLOGY (2000)