4.7 Article

Iatrogenic influence on prognosis of radiation-induced contrast enhancements in patients with glioma WHO 1-3 following photon and proton radiotherapy

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Oncology

Radiation induced contrast enhancement after proton beam therapy in patients with low grade glioma - How safe are protons?

Semi B. Harrabi et al.

Summary: This study aimed to evaluate the clinical outcomes of proton beam therapy for low-grade glioma patients, with a focus on morphologic features on MRI. The results showed that proton irradiation led to significantly improved overall survival and progression-free survival for patients. However, the incidence of radiation-induced contrast-enhancing lesions was higher than expected, and these lesions were mainly observed at the distal end of the proton beam. The average linear energy transfer (LET) inside the contrast-enhancing lesions was significantly increased compared to dose-matched voxels outside the lesions. These findings provide clinical evidence to support the hypothesis that the relative biological effectiveness of protons is variable.

RADIOTHERAPY AND ONCOLOGY (2022)

Article Oncology

Radiation-induced contrast enhancement following proton radiotherapy for low-grade glioma depends on tumor characteristics and is rarer in children than adults

Tanja Eichkorn et al.

Summary: This study analyzed the outcomes of proton beam radiotherapy in 227 patients with low-grade glioma. The results showed that proton beam radiotherapy was effective in treating LGG in both children and adults. The incidence of radiation-induced contrast enhancements was higher in adults compared to children, and was associated with WHO grading.

RADIOTHERAPY AND ONCOLOGY (2022)

Article Oncology

Brain Necrosis in Adult Patients After Proton Therapy: Is There Evidence for Dependency on Linear Energy Transfer?

Andrzej Niemierko et al.

Summary: The study aimed to investigate the correlation between radiographic imaging changes, specifically necrosis, and regions with elevated LET in proton therapy treatments. The results did not find an association between LET adjusted for dose and the risk of brain necrosis. Difficulties in voxel-based analysis of brain necrosis include uncertainties in necrosis origin, timing of imaging, variability in patient specific radiosensitivity, and the simultaneous effect of dose and LET.

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2021)

Article Radiology, Nuclear Medicine & Medical Imaging

How can scanned proton beam treatment planning for low-grade glioma cope with increased distal RBE and locally increased radiosensitivity for late MR-detected brain lesions?

Julia Bauer et al.

Summary: A novel risk model for late contrast-enhancing brain lesions (CEBLs) after proton irradiation of low-grade glioma (LGG) patients has shown a strong dependence on dose-weighted linear-energy transfer (LETd effect) and increased radiosensitivity of the ventricular proximity. Multiple-field treatment plans can reduce normal tissue complication probability (NTCP) in low-risk groups but not in high-risk groups. Advanced biologically guided treatment planning approaches are crucial for minimizing risks in proton therapy of LGG, especially in high-risk patients.

MEDICAL PHYSICS (2021)

Article Oncology

Adjuvant and concurrent temozolomide for 1p/19q non-co-deleted anaplastic glioma (CATNON; EORTC study 26053-22054): second interim analysis of a randomised, open-label, phase 3 study

Martin J. van den Bent et al.

Summary: The CATNON trial investigated the role of temozolomide in combination with radiotherapy for patients with 1p/19q non-co-deleted anaplastic gliomas. Adjuvant temozolomide was found to improve overall survival, while concurrent temozolomide showed no benefit.

LANCET ONCOLOGY (2021)

Article Clinical Neurology

Proton therapy for newly diagnosed pediatric diffuse intrinsic pontine glioma

Ai Muroi et al.

CHILDS NERVOUS SYSTEM (2020)

Article Oncology

Outcomes Following Proton Therapy for Pediatric Low-Grade Glioma

Daniel J. Indelicato et al.

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2019)

Review Biochemistry & Molecular Biology

Bevacizumab treatment for radiation brain necrosis: mechanism, efficacy and issues

Hongqing Zhuang et al.

MOLECULAR CANCER (2019)

Article Radiology, Nuclear Medicine & Medical Imaging

Imaging Glioblastoma Posttreatment Progression, Pseudoprogression, Pseudoresponse, Radiation Necrosis

Sara B. Strauss et al.

RADIOLOGIC CLINICS OF NORTH AMERICA (2019)

Article Oncology

Radiation Necrosis and White Matter Lesions in Pediatric Patients With Brain Tumors Treated With Pencil Beam Scanning Proton Therapy

Beat Bojaxhiu et al.

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2018)

Article Oncology

Bevacizumab Monotherapy Reduces Radiation-induced Brain Necrosis in Nasopharyngeal Carcinoma Patients: A Randomized Controlled Trial

Yongteng Xu et al.

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2018)

Review Oncology

Diagnosis and Management of Radiation Necrosis in Patients With Brain Metastases

Balamurugan Vellayappan et al.

FRONTIERS IN ONCOLOGY (2018)

Review Radiology, Nuclear Medicine & Medical Imaging

Radiation Necrosis, Pseudoprogression, Pseudoresponse, and Tumor Recurrence: Imaging Challenges for the Evaluation of Treated Gliomas

Anastasia Zikou et al.

CONTRAST MEDIA & MOLECULAR IMAGING (2018)

Article Medicine, General & Internal

The 2016 World Health Organization classification of tumours of the central nervous system

Chiara Villa et al.

PRESSE MEDICALE (2018)

Article Clinical Neurology

Radiation Necrosis in Pediatric Patients with Brain Tumors Treated with Proton Radiotherapy

S. F. Kralik et al.

AMERICAN JOURNAL OF NEURORADIOLOGY (2015)

Article Radiology, Nuclear Medicine & Medical Imaging

Diagnosis of pseudoprogression in patients with glioblastoma using O-(2-[18F]fluoroethyl)-L-tyrosine PET

Norbert Galldiks et al.

EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2015)

Article Oncology

Low-Grade Gliomas

Deborah A. Forst et al.

ONCOLOGIST (2014)

Article Clinical Neurology

Diagnostic Accuracy of PET for Recurrent Glioma Diagnosis: A Meta-Analysis

T. Nihashi et al.

AMERICAN JOURNAL OF NEURORADIOLOGY (2013)

Article Radiology, Nuclear Medicine & Medical Imaging

18F-FDOPA PET/CT for detection of recurrence in patients with glioma: prospective comparison with 18F-FDG PET/CT

Sellam Karunanithi et al.

EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2013)

Article Neurosciences

Radiation-induced blood-brain barrier damages: An in vitro study

William Fauquette et al.

BRAIN RESEARCH (2012)

Article Oncology

RANDOMIZED DOUBLE-BLIND PLACEBO-CONTROLLED TRIAL OF BEVACIZUMAB THERAPY FOR RADIATION NECROSIS OF THE CENTRAL NERVOUS SYSTEM

Victor A. Levin et al.

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2011)

Article Clinical Neurology

Pseudoprogression and pseudoresponse in the treatment of gliomas

Dieta Brandsma et al.

CURRENT OPINION IN NEUROLOGY (2009)

Review Medicine, General & Internal

CNS complications of radiotherapy and chemotherapy

Carole Soussain et al.

LANCET (2009)

Article Radiology, Nuclear Medicine & Medical Imaging

Diagnostic accuracy of 11C-methionine PET for differentiation of recurrent brain tumors from radiation necrosis after radiotherapy

Yuzo Terakawa et al.

JOURNAL OF NUCLEAR MEDICINE (2008)

Article Oncology

Molecular targets in radiation-induced blood-brain barrier disruption

RA Nordal et al.

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2005)