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Association of the promoter haplotype in CDK5 gene with schizophrenia in a Korean population

PSYCHIATRY RESEARCH (2022)

Effects of JL13, a pyridobenzoxazepine compound, in dopaminergic and glutamatergic models of antipsychotic activity

Yane C. P. Andrade et al.

Summary: JL13, a novel pyridobenzoxazepine compound, shows potential as an antipsychotic drug by preventing hyperlocomotion induced by dopamine and glutamate modulators in animal models. It also demonstrates efficacy in preventing disruption of PPI caused by MK-801. This compound possesses a favorable pharmacological profile similar to second-generation antipsychotics.

BEHAVIOURAL PHARMACOLOGY (2021)

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Review Biochemistry & Molecular Biology

Decreased Brain pH and Pathophysiology in Schizophrenia

Hae-Jeong Park et al.

Summary: Postmortem studies have shown that schizophrenia patients have lower brain pH levels, with implications for the role of this phenomenon in disease progression being discussed in depth. Changes in mitochondrial morphology and function in schizophrenia patients may contribute to abnormal metabolism. Alterations in pH levels could have effects on neuronal activity and pathophysiology.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

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Article Genetics & Heredity

Novel rare variations in genes that regulate developmental change in N-methyl-D-aspartate receptor in patients with schizophrenia

Akane Yoshikawa et al.

HUMAN GENOME VARIATION (2018)

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Article Multidisciplinary Sciences

Cyclin-dependent Kinase 5: Novel role of gene variants identified in ADHD

Subhamita Maitra et al.

SCIENTIFIC REPORTS (2017)

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Article Clinical Neurology

Cyclin-dependent kinase-5 and p35/p25 activators in schizophrenia and major depression prefrontal cortex: basal contents and effects of psychotropic medications

Alfredo Ramos-Miguel et al.

INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2013)

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Article Clinical Neurology

Schizophrenia is associated with dysregulation of a Cdk5 activator that regulates synaptic protein expression and cognition

Olivia Engmann et al.

BRAIN (2011)

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Article Neurosciences

Both N-methyl-D-aspartate (NMDA) and non-NMDA receptors mediate glutamate-induced cleavage of the cyclin-dependent kinase 5 (cdk5) activator p35 in cultured rat hippocampal neurons

P Kerokoski et al.

NEUROSCIENCE LETTERS (2004)

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Association of the promoter haplotype in CDK5 gene with schizophrenia in a Korean population

相关参考文献

Effects of JL13, a pyridobenzoxazepine compound, in dopaminergic and glutamatergic models of antipsychotic activity

Decreased Brain pH and Pathophysiology in Schizophrenia

Novel rare variations in genes that regulate developmental change in N-methyl-D-aspartate receptor in patients with schizophrenia

Cyclin-dependent Kinase 5: Novel role of gene variants identified in ADHD

Cyclin-dependent kinase-5 and p35/p25 activators in schizophrenia and major depression prefrontal cortex: basal contents and effects of psychotropic medications

Schizophrenia is associated with dysregulation of a Cdk5 activator that regulates synaptic protein expression and cognition

Both N-methyl-D-aspartate (NMDA) and non-NMDA receptors mediate glutamate-induced cleavage of the cyclin-dependent kinase 5 (cdk5) activator p35 in cultured rat hippocampal neurons

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